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CONCEPT OF DISEASE
CAUSATION AND THEIR
SCREENING
By: Nikita Saliya
1st year M.sc Nursing
CMPCON
Outline
• Introduction and definition of health.
A. Concepts of disease causation
I. Theories of disease
II. Natural history of disease
III. Iceberg phenomenon
B. Disease screening
I. Aims and objectives of screening
II. Uses of screening
III. Types of screening
Definition of health
• According to WHO, “Health is a state of complete physical,
mental, social and spiritual wellbeing and not merely an
absence of diseases or infirmity”
Supernatural theory
• A punishment from God for a sinful behavior.
• e.g. curse of God; an evil eye
Ayurveda
• The disease is due to imbalance of the ‘tridosha’
• Vatta (air), pitta (bile), and kapha (mucus)
Miasma Theory
• The word "miasma" means "pollution".
• Miasma was considered to be a poisonous vapor or mist
filled with particles from decomposed matter (miasmata)
that caused illnesses.
Germ theory
• Health problems were believed to be the product of living
organisms which entered the body through food, water, air or
the bites of insects or animals.
Cont.
• It was believed that each disease has a single and
a specific cause (mono-causal approach).
The result of the Germ Theory:
• Researches were moved from the community to the
laboratory and concentrated on the identification of agents
for a given disease.
Biomedical model
• Disease as a result of malfunctioning of organs or
cells
• For e.g. Diabetes is caused by malfunctioning of
pancreas
Epidemiological triad
• According to this theory,
exposure to an agent
does not necessarily lead
to disease.
• It was believed that
disease is the result of an
interaction between
agent, host and the
environment.
AGENT
Multifactorial causation theory
• Disease is not only caused by an organism but also
predisposed by many factors contributing to its
occurrence
Multifactorial causation theory
LAZARU’S THEORY OF STRESS
RESPONSE
• According to him, in the process of coping, the
individual responds to a stress, which can have an
impact on the client’s resistance to disease.
HOLMES AND RAHE’S THEORY
OF LIFE CHANGES
• They explored the relationship between the amount of change
in a person’s life and subsequent illness.
• The higher a person’s life changes score, the greater is the like
hood that an illness would develop.
Web of causation
• Given by Mac Mohan and Pugh
• According to this concept, disorders are developed through
complex interaction of many factors.
• These factors maybe biophysical, social or psychological.
• Chain which may be a fraction of the whole complex is known
as a web of causation.
Theory of general susceptibility
• It seeks to understand why some social groups seems to
be more susceptible to disease and death in general.
Natural history of disease
• In the absence of any intervention (preventive or treatment), all
diseases follow a natural course of events which refers to
natural history of disease.
• The natural history of disease occurs in two phases pre-
pathogenesis and pathogenesis
Phases
Prepathoge-
nesis phase
Before
onset of
disease
Favourable
environment
& host
Agent
(outside the
host)
Pathogenesis
phase
Incubation
period
Early
pathogenes
is
Late
pathogenes
is
Agent
Biological
agent
Nutrient
agent
Physical
agent
Chemical
agent
Mechanic
al agent
Social
agent
Exogenous
Age and gender
Income
Marital status
Life style
Nutritional status
Occupation & literacy
Ethnicity
HOST
Environmental
risk factor
Biological
environment
Physical
environment
Sociological
environment
Iceberg phenomenon
Screening for disease
• Search for unrecognized disease or
defect by means of rapidly applied test,
examinations or other procedures.
Aims and objectives of screening
• Sort out apparently healthy persons likely to have the
disease
• Bring apparently abnormal under medical supervision
and treatment
Uses of screening
Types of screening
Criteria of test for screening
Evaluations of screening
programmes
concepts of disease causation
concepts of disease causation

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