Cholera is an acute infectious disease caused by the bacterium Vibrio cholerae characterized by severe watery diarrhea and dehydration. While rare in developed nations, it remains a major public health issue in developing countries, with millions of cases reported annually. Transmission occurs through contaminated food or water. Prevention focuses on proper sanitation, handwashing, and drinking safe water. Nursing care centers around rehydration and electrolyte replacement to treat dehydration and other complications from fluid loss.