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The Medical Beast Page 1
CHEST PAIN
Diagnostic Pathophysiology Past history Complains Physical signs ECG Chest X-Ray Treatment
CARDIOVASCULAR
Angina pectoris Temporary
myocardial
ischemia, usually
secondary to
atherosclerosis
Man of > 50
years with
Cardiovascular
risk factors
Retrosternal,
radiating to the
shoulders, arms,
neck, lower jaw
or upper
abdomen
Normal OK IN ANGINA
-hyper acute T
waves(tall and
symmetric)
-ST elevation
-significant Q
waves
(>40msec OR
>1/3 QRS)
-inverted T
waves
NORMAL -General measures
-Antiplatelet
therapy
-B-blockers
-Nitrates
-CCB
-ACE inhibitors
-Invasive strategies
Myocardial
infarction
Prolong ischemia
>30 min
Same as in
angina, but >30
min
Possible
hemodynamic
changes
NORMAL
Pericarditis Irritation of the
parietal pleura
adjacent to the
pericardium
Viral infection,
Autoimmune
disorders, post-
myocardial
infarction
Sharp, knifelike
pain, relieve
when leaning
forward
Pericardial
friction rub
-Diffuse ST
elevation
-PR segment
depression
-upright T
waves
-isoelectric ST,
flat or inverted
T waves
Cardiomegaly,
rounded
cardiac
countour
-treat underlying
disease
-high dose NSAIDs
-colchicine rate of
incessant/recurrent
pericarditis
Aortic
dissection
A splitting within
the layers of the
aortic wall
Hypertension
Marfan
syndrome
tearing chest
pain, radiating
to the neck,
back or
abdomen
Aortic
insufficiency
murmur,
Weak pulses
normal Enlargement of
the aortic arc
Surgery
PULMONARY
The Medical Beast Page 2
Pulmonary
embolism
Lodging of a blood
clot in the
pulmonary
arterial tree
Immobilization
Post-operative
Malignancy
coagulopathy
Sudden
dyspnea, fever,
chest pain
30% calf swelling
And tenderness
-Sinus
tachycardia,
-S1Q3T3
pattern
-Hampton’s
hump
-westermark’s
sign
-atelectasis
-elevation of
hemidiaphram
Oxygen, analgesics,
acute AND long
term
anticoagulation, IV
thrombolytic, ITT,
IVC filter,
thromboprophylaxis
Pleural effusion Liquid in pleural
space
Pneumonia, TB,
CHF, nephrotic
syndrome
Cough,
Dyspnea,
Pleuritic chest
pain
Dullness,
decrease tactile
fremitus/ breath
sounds
Dense
opacification
with concave
meniscus
Thoracocentesis,
Treat underlying
cause
Pneumothorax Air in pleural
space
Previous
trauma,
emphysema
Hyperresonance,
diminished
breath
sounds/tactile
fremitus
Separation of
visceral and
parietal pleura
Small (<20%):
nothing
Large: chest tube
Treat underlying
cause
Pneumonia Lung Infection Dullness,
bronchial breath
sounds, crackles
Lobar
consolidation
or interstitial
pattern
Antibiotics, IV
fluids, O2
GASTROINTESTINAL AND OTHER
Oesophageal
spasm
Muscle
dysfunction of the
esophageal
muscle
Retrosternal
brutal
squeezing pain
Nitrates, CCB,
anticholinergics.
Esophageal
myotomy
Reflux
esophagitis
Inflammation of
the esophageal
mucosa by reflux
of gastric acid
Burning pain,
increased when
bending over,
lying down
Possible Hiatal
hernia
PPIs, antacids,
H2-blockers
Costochondritis variable Stabbing,
sticking local
pain
Sterno-costal
joint tenderness
Possible
erosion of
sterno-costal
joint
NSAIDs

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Chest pain

  • 1. The Medical Beast Page 1 CHEST PAIN Diagnostic Pathophysiology Past history Complains Physical signs ECG Chest X-Ray Treatment CARDIOVASCULAR Angina pectoris Temporary myocardial ischemia, usually secondary to atherosclerosis Man of > 50 years with Cardiovascular risk factors Retrosternal, radiating to the shoulders, arms, neck, lower jaw or upper abdomen Normal OK IN ANGINA -hyper acute T waves(tall and symmetric) -ST elevation -significant Q waves (>40msec OR >1/3 QRS) -inverted T waves NORMAL -General measures -Antiplatelet therapy -B-blockers -Nitrates -CCB -ACE inhibitors -Invasive strategies Myocardial infarction Prolong ischemia >30 min Same as in angina, but >30 min Possible hemodynamic changes NORMAL Pericarditis Irritation of the parietal pleura adjacent to the pericardium Viral infection, Autoimmune disorders, post- myocardial infarction Sharp, knifelike pain, relieve when leaning forward Pericardial friction rub -Diffuse ST elevation -PR segment depression -upright T waves -isoelectric ST, flat or inverted T waves Cardiomegaly, rounded cardiac countour -treat underlying disease -high dose NSAIDs -colchicine rate of incessant/recurrent pericarditis Aortic dissection A splitting within the layers of the aortic wall Hypertension Marfan syndrome tearing chest pain, radiating to the neck, back or abdomen Aortic insufficiency murmur, Weak pulses normal Enlargement of the aortic arc Surgery PULMONARY
  • 2. The Medical Beast Page 2 Pulmonary embolism Lodging of a blood clot in the pulmonary arterial tree Immobilization Post-operative Malignancy coagulopathy Sudden dyspnea, fever, chest pain 30% calf swelling And tenderness -Sinus tachycardia, -S1Q3T3 pattern -Hampton’s hump -westermark’s sign -atelectasis -elevation of hemidiaphram Oxygen, analgesics, acute AND long term anticoagulation, IV thrombolytic, ITT, IVC filter, thromboprophylaxis Pleural effusion Liquid in pleural space Pneumonia, TB, CHF, nephrotic syndrome Cough, Dyspnea, Pleuritic chest pain Dullness, decrease tactile fremitus/ breath sounds Dense opacification with concave meniscus Thoracocentesis, Treat underlying cause Pneumothorax Air in pleural space Previous trauma, emphysema Hyperresonance, diminished breath sounds/tactile fremitus Separation of visceral and parietal pleura Small (<20%): nothing Large: chest tube Treat underlying cause Pneumonia Lung Infection Dullness, bronchial breath sounds, crackles Lobar consolidation or interstitial pattern Antibiotics, IV fluids, O2 GASTROINTESTINAL AND OTHER Oesophageal spasm Muscle dysfunction of the esophageal muscle Retrosternal brutal squeezing pain Nitrates, CCB, anticholinergics. Esophageal myotomy Reflux esophagitis Inflammation of the esophageal mucosa by reflux of gastric acid Burning pain, increased when bending over, lying down Possible Hiatal hernia PPIs, antacids, H2-blockers Costochondritis variable Stabbing, sticking local pain Sterno-costal joint tenderness Possible erosion of sterno-costal joint NSAIDs