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Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Chapter 17
Functional Capacity of the
Cardiovascular System
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Cardiac Output
• Cardiac output (Q) = HR × SV
• Methods of Measuring Q
– Direct Fick
– Indicator dilution
– CO2 rebreathing
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Direct Fick Method
Q = O2 mL · min−1
a- O2 difference
v
V

Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Indicator Dilution Method
Q = Quantity of dye injected
Average dye
concentration blood × Duration of curve
for duration of curve
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
CO2 Rebreathing Method
Q = CO2 × 100
-aCO2 difference
v
V

Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Cardiac Output at Rest
• Values vary depending upon emotional
state.
• Average male ~5 L · min-1
• Average female ~4 L · min-1
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Untrained Characteristics of Q
• HR ~ 70 BPM
• SV ~ 71.4 mL
• Average women ~25% lower due to smaller
size
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Endurance Athletes
• Characteristics of Q
– HR ~ 50 BPM
– SV ~ 100 mL
• Mechanisms
– Increased vagal tone w/decreased sympathetic
drive
– Increased blood volume
– Increased myocardial contractility and
compliance of left ventricle
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Cardiac Output During Exercise
• Q increases rapidly during transition from
rest to exercise.
• Q at max exercise increases up to 4 times.
Q HR SV
Untrained 22 L 195 113 mL
Trained 35 L 195 179 mL
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Stroke Volume: Diastolic Filling vs.
Systole Emptying
• Mechanisms for increased SV with
training
– Increased blood volume – increase diastolic
filling
– Increased preload – Starling’s Law of the
Heart
– Increased Contractility – greater systolic
emptying
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Cardiovascular Drift
• Results from
– Dehydration
– Reduction in SV
• HR drifts upward to maintain same Q
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Cardiac Output Distribution
• Blood flows to tissues in proportion to
their metabolic activity.
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Cardiac Output and Oxygen
Transport
Rest
Q = 5 L · min-1
O2 transport = 1,000 mL – 200 mL/L blood
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Exercise
• Max Q averages ~ 16 L · min-1
• O2 transport = 200 mL/L blood
• Result
– 3200 mL O2
• Training enables Q to increase up to
40 L · min-1, increasing O2 transport
up to 8,000 mL.
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Close Association Between
Max Q and O2max
• An almost proportionate increase in max Q
accompanies increases in O2max with training.
V

V

Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Cardiac Output Differences:
Men, Women, and Children
• Women have a 10% lower hemoglobin level than
men.
• Result is a 5 – 10% increase in Q at any submax
level of O2 consumption
• Children have higher HR
– Result is smaller Q, expanded a- O2
v
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
O2 Extraction: The a- O2 Difference
• O2 consumption increases during exercise.
– Increases Q
– Increases extraction of O2 by tissues
• O2 = Q x a- O2 difference
v
v
V

V

Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
a- O2 Difference during Rest
• 20 mL O2 · dL-1 arterial blood
• 15 mL O2 · dL-1 venous blood
• 5 mL a- O2diff
v
v
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
a- O2 Difference during Exercise
• 20 mL O2 · dL-1 arterial blood
• 5 – 15 mL O2 · dL-1 venous blood
• Up to a threefold increase in O2 extraction
v
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Severe Heart Disease
• Exhibit low ability to improve Q or SV
• Skeletal muscle adaptations allow for
increased O2 extraction.
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Factors Affecting the a- O2
Differences
• Redistribution of flow to active tissues during
exercise
• Increased capillary density due to training increases
surface area and O2 extraction
• Increased number and size of mitochondria
• Increased oxidative enzymes
• Vascular and metabolic improvements
v
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Cardiovascular Adjustments to
Upper-Body Exercise
• Max O2 consumption
– Upper-body exercise results in max O2
consumption ~20 – 30% lower than
lower-body exercise.
• Higher O2 consumption for a given submax
workload
– Lower mechanical efficiency
– Muscular effort to stabilize torso
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Physiologic Response
• Submaximal arm exercise produces
> HR
> Pulmonary ventilations
> RPE
> BP response
than comparable leg exercise
Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy,
Nutrition, and Human Performance, Sixth Edition
Physiologic Response
• Exercise prescription for arm exercise
should not be based on values obtained
from lower-body exercises.

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Chapter17 Functional Capacity of CV System (2).ppt

  • 1. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Chapter 17 Functional Capacity of the Cardiovascular System
  • 2. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Cardiac Output • Cardiac output (Q) = HR × SV • Methods of Measuring Q – Direct Fick – Indicator dilution – CO2 rebreathing
  • 3. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Direct Fick Method Q = O2 mL · min−1 a- O2 difference v V 
  • 4. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition
  • 5. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Indicator Dilution Method Q = Quantity of dye injected Average dye concentration blood × Duration of curve for duration of curve
  • 6. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition CO2 Rebreathing Method Q = CO2 × 100 -aCO2 difference v V 
  • 7. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Cardiac Output at Rest • Values vary depending upon emotional state. • Average male ~5 L · min-1 • Average female ~4 L · min-1
  • 8. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Untrained Characteristics of Q • HR ~ 70 BPM • SV ~ 71.4 mL • Average women ~25% lower due to smaller size
  • 9. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Endurance Athletes • Characteristics of Q – HR ~ 50 BPM – SV ~ 100 mL • Mechanisms – Increased vagal tone w/decreased sympathetic drive – Increased blood volume – Increased myocardial contractility and compliance of left ventricle
  • 10. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Cardiac Output During Exercise • Q increases rapidly during transition from rest to exercise. • Q at max exercise increases up to 4 times. Q HR SV Untrained 22 L 195 113 mL Trained 35 L 195 179 mL
  • 11. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Stroke Volume: Diastolic Filling vs. Systole Emptying • Mechanisms for increased SV with training – Increased blood volume – increase diastolic filling – Increased preload – Starling’s Law of the Heart – Increased Contractility – greater systolic emptying
  • 12. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Cardiovascular Drift • Results from – Dehydration – Reduction in SV • HR drifts upward to maintain same Q
  • 13. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Cardiac Output Distribution • Blood flows to tissues in proportion to their metabolic activity.
  • 14. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition
  • 15. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition
  • 16. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Cardiac Output and Oxygen Transport Rest Q = 5 L · min-1 O2 transport = 1,000 mL – 200 mL/L blood
  • 17. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Exercise • Max Q averages ~ 16 L · min-1 • O2 transport = 200 mL/L blood • Result – 3200 mL O2 • Training enables Q to increase up to 40 L · min-1, increasing O2 transport up to 8,000 mL.
  • 18. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Close Association Between Max Q and O2max • An almost proportionate increase in max Q accompanies increases in O2max with training. V  V 
  • 19. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition
  • 20. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Cardiac Output Differences: Men, Women, and Children • Women have a 10% lower hemoglobin level than men. • Result is a 5 – 10% increase in Q at any submax level of O2 consumption • Children have higher HR – Result is smaller Q, expanded a- O2 v
  • 21. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition O2 Extraction: The a- O2 Difference • O2 consumption increases during exercise. – Increases Q – Increases extraction of O2 by tissues • O2 = Q x a- O2 difference v v V  V 
  • 22. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition a- O2 Difference during Rest • 20 mL O2 · dL-1 arterial blood • 15 mL O2 · dL-1 venous blood • 5 mL a- O2diff v v
  • 23. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition a- O2 Difference during Exercise • 20 mL O2 · dL-1 arterial blood • 5 – 15 mL O2 · dL-1 venous blood • Up to a threefold increase in O2 extraction v
  • 24. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Severe Heart Disease • Exhibit low ability to improve Q or SV • Skeletal muscle adaptations allow for increased O2 extraction.
  • 25. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Factors Affecting the a- O2 Differences • Redistribution of flow to active tissues during exercise • Increased capillary density due to training increases surface area and O2 extraction • Increased number and size of mitochondria • Increased oxidative enzymes • Vascular and metabolic improvements v
  • 26. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Cardiovascular Adjustments to Upper-Body Exercise • Max O2 consumption – Upper-body exercise results in max O2 consumption ~20 – 30% lower than lower-body exercise. • Higher O2 consumption for a given submax workload – Lower mechanical efficiency – Muscular effort to stabilize torso
  • 27. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition
  • 28. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Physiologic Response • Submaximal arm exercise produces > HR > Pulmonary ventilations > RPE > BP response than comparable leg exercise
  • 29. Copyright © 2007 Lippincott Williams & Wilkins. McArdle, Katch, and Katch: Exercise Physiology: Energy, Nutrition, and Human Performance, Sixth Edition Physiologic Response • Exercise prescription for arm exercise should not be based on values obtained from lower-body exercises.