Aerobic means utilization of oxygen. So, aerobic exercise or training involves our cardio-respiratory system to produce energy. Here, the amount of oxygen utilized due to respiration is proportionate to energy production.
Here, we will focus on the following topics:
Sources of aerobic energy in our body, Aerobic training methods, Different aerobic exercises, Benefits of aerobic training and
its drawbacks.
Evidence based practice (EBP) in physiotherapy Saurab Sharma
This presentation is the classroom lecture for undergraduate physiotherapy students whom I teach at Kathmandu University School of Medical Sciences in Nepal. This is an introductory lecture. Students carry on with steps of EBP in the years to come during the student life and use it for their presentations and clinical learning placement.
Other students too may benefit. I highly encourage other students, especially in some parts of India where EBP is not taught, and is reserved for Master's degree program. I completely disagree with this concept, as EBP is the pillar of a responsible physiotherapy practice. Early it starts, better it is.
Evidence based practice (EBP) in physiotherapy Saurab Sharma
This presentation is the classroom lecture for undergraduate physiotherapy students whom I teach at Kathmandu University School of Medical Sciences in Nepal. This is an introductory lecture. Students carry on with steps of EBP in the years to come during the student life and use it for their presentations and clinical learning placement.
Other students too may benefit. I highly encourage other students, especially in some parts of India where EBP is not taught, and is reserved for Master's degree program. I completely disagree with this concept, as EBP is the pillar of a responsible physiotherapy practice. Early it starts, better it is.
“To enjoy the glow of good health, you must exercise”
Fitness is a big part of who I am !!!
“Your Health is Our Mission”. Fitness is a big part of who I am !! To keep the body in good health is a duty…..otherwise we shall not be able to keep our mind strong and clear.
In this i have covered the different sports injuries of upper extremities, their causes and their orthotic management.
Helpful for those, who are in the field of P & O.
The biggest benefit of Exercise Stability ball is that they are very effective at targeting muscles & good postures. For more details about Exercise Stability ball visit here at http://www.amazon.com/Exercise-Stability-Ball-Eco-Friendly-Birthing/dp/B00G4UFZS2
Clinical research is quite vital in the field of physiotherapy. Physiotherapists depends on information from researches to enhance the knowledge they have already gained through their university education and with continuous education courses.
“To enjoy the glow of good health, you must exercise”
Fitness is a big part of who I am !!!
“Your Health is Our Mission”. Fitness is a big part of who I am !! To keep the body in good health is a duty…..otherwise we shall not be able to keep our mind strong and clear.
In this i have covered the different sports injuries of upper extremities, their causes and their orthotic management.
Helpful for those, who are in the field of P & O.
The biggest benefit of Exercise Stability ball is that they are very effective at targeting muscles & good postures. For more details about Exercise Stability ball visit here at http://www.amazon.com/Exercise-Stability-Ball-Eco-Friendly-Birthing/dp/B00G4UFZS2
Clinical research is quite vital in the field of physiotherapy. Physiotherapists depends on information from researches to enhance the knowledge they have already gained through their university education and with continuous education courses.
Peak Performance Of A Marathon Runner With A Sub 2 Hr 40 Race TimeCarl Page
In this physiology assignment discusses how the cardio-respiratory systems facilitate the energy systems that are used during a peak performance of a marathon runner with a sub 2 hr 40 race time. Also suggests and justifies a physiological assessment which could be used to help understand the person’s fitness and specific physiological responses to exercise.
Building Elite Cardio for Competative Boxingringsiderising
If you train hard for boxing and your cardio still isn't great, there is a reason. Your training regimen isn't taking energy systems into account. If you aren't training your aerobic system to work with your anaerobic alactic and anaerobic lactic systems, then you may as well be training to not be the best. So if you LIKE losing and gassing out, skip this e-book. For all of those people who want to separate themselves from the mediocre fighters with ok conditioning, this e-book will put you on the right track. You're welcome!
Aerobic means "with oxygen," and anaerobic means "without oxygen." Anaerobic exercise is the type where you get out of breath in just a few moments, like when you lift weights for improving strength, when you sprint, or when you climb a long flight of stairs.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Predicting property prices with machine learning algorithms.pdf
Aerobic training and aerobic energy source
1. 1 / 12
Aerobic training
By Ratnodip Saha
thanks to Swarnali Biswas, Dip Das Chowdhury, Nitika Khan & Arghya Biswas
2. 2 / 12
What is Aerobic training?
●
Aerobic means utilization of oxygen. So,
aerobic exercise or training involves our cardio-
respiratory system to produce energy. Here, the
amount of oxygen utilized due to respiration is
proportionate to energy production.
●
Here, we will focus on the following topics:
Sources of aerobic energy in our body,
Aerobic training methods, Different aerobic
exercises, Benefits of aerobic training and
its drawbacks.
3. 3 / 12
Sources of aerobic energy in body
●
In aerobic respiration, food glucose is converted into energy in
presence of oxygen. Here, the derived chemical equation is:
Glucose (C6
H12
O6
) + Oxygen (O2
) Carbon-dioxide 6(CO2
) + Water
6(H2
O) + Energy (ATP)
●
2900 kilo-joule of energy is produced from breakdown of one
glucose molecule and in turn, this energy is used to produce
ATP which is used by various physiological systems of our body.
●
Aerobic energy involves
1. glycolysis
2. oxidative decarboxylation
of pyruvate
3. Krebs cycle
4. oxidative phosphorylation
4. 4 / 12
Sources of aerobic energy in body
1) Glycolysis: Glycolysis is the first stage of aerobic
respiration and occurs in the cytoplasm of the cell. It
involves the splitting of 1 six-carbon sugar molecule
into 2 three-carbon pyruvate molecules. This process
creates two ATP molecules.
C6
H12
O6
+ 2 ADP + 2 PI + 2 NAD+
→ 2 Pyruvate + 2 ATP + 2 NADH + 2 H+
+ 2 H2
O
2) Formation of Acetyl CoA: Pyruvate is transferred into
the mitochondrial matrix via a protein known as pyruvate
translocase. Here, the pyruvate is combined with
Coenzyme A to release a carbon dioxide molecule and
form acetyl-CoA.
2 (Pyruvate–
+ Coenzyme A + NAD+
→ Acetyl CoA + CO2
+ NADH)
5. 5 / 12
Sources of aerobic energy in body
3) Krebs cycle: The third step is the citric acid cycle or
Krebs cycle. In this stage, the oxaloacetate combines
with the acetyl-coenzyme A and produces citric acid.
The citric acid cycle undergoes a series of reactions and
produces 2 molecules of carbon dioxide, 1 molecule
of ATP, and reduced forms of NADH and FADH. This
cycle occurs twice per glucose molecule.
4) Oxidative phosphorylation: In this stage, by means of
oxidative phosphorylation, large amounts of ATP
molecules are produced by transferring the electrons from
NADH and FADH.
34 (ADP + PI + NADH + 1/2 O2
+ 2H+
→ ATP + NAD+
+ 2 H2
O)
Thus, a single molecule of glucose produces 30 molecules of ATP, 6 molecules of
CO2
and 6 molecules of H2
O.
6. 6 / 12
Methods of Aerobic training
A) Continuous training: It is a form of exercise that is
performed at a continuous intensity throughout and doesn’t
involve any rest periods. Continuous training typically involves
aerobic activities such as running, biking, swimming and
rowing. These activities use large muscle groups performing
repetitive movements over a prolonged period of time.
It can be performed at a low, moderate or moderate-high
intensity depending on what an individual wants to achieve
from the training and the current fitness levels.
Rowing
7. 7 / 12
Methods of Aerobic training
B) Interval training: Interval training is defined as high-intensity
intermittent exercise where exercises of high intensity are
practiced involving regular rest intervals. In this type of
training, a person trains at a high exercise intensity with
minimal fatigue that would normally prove exhausting if done
continuously.
Activities like push ups, pull ups, jump ropes etc. are generally
practiced with regular intervals. It improves aerobic capacity
and helps the individual to exercise for longer and at more
intense levels.
Jump rope
8. 8 / 12
Different types of aerobic exercise
Indoor Outdoor Indoor or Outdoor
Elliptical trainer Walking Swimming
Indoor rower Cycling Kickboxing
Stair climbing Running Skipping rope or jump rope
Treadmill Cross-country skiing Circuit training
Aerobic dancing Cross-country running Jumping jacks
Jazzercise Nordic walking Water aerobics
Step aerobics Inline skating Jogging
Skateboarding Stair climbing
Rowing
Source:
Wikipedia
9. 9 / 12
Effects of aerobic exercise in human body
Changes Details
Heart rate (HR) Resting HR decreases with aerobic training and is lower at any given
workload. The maximum HR is unchanged.
Cardiac output (CO) Maximum CO increases, whereas resting CO is stable. Resting SV
increases, with a corresponding decrease in the resting HR.
Maximum oxygen
consumption
With the increase of work rate, oxygen uptake increases linearly.
Above a certain work rate oxygen consumption reaches a plateau (VO2
max). In an average young male, resting oxygen consumption is about
250 ml min−1
and in an athlete oxygen consumption during very high
intensity exercise might reach 5000 ml min−1
.
Stroke volume (SV)
SV increases sharply at exercise onset up to around 40% consequent to
increased blood volume, venous return, and filling pressures according
to the Frank–Starling mechanism.
Ventilation
Ventilation increases abruptly in the initial stages of exercise and is
then followed by a more gradual increase. During exercise, ventilation
might increase from resting values of around 5-6 L min−1
to
>100 L min−1
.
10. 10 / 12
Health benefits of aerobic exercise
✔ Improves cardiovascular conditioning.
✔ Decreases risk of heart disease.
✔ Lowers blood pressure.
✔ Increases HDL or good cholesterol.
✔ Helps to better control blood sugar.
✔ Assists in weight management and/or weight loss.
✔ Improves lung function.
✔ Decreases resting heart rate.
11. 11 / 12
Drawbacks of aerobic exercise
✗ Overuse injuries may occur due to repetitive, high-impact
exercise such as distance running.
✗ Not an effective form of fat loss. Beginners may experience a
fast fat loss process but experienced practitioners will combine
scientific diets and anaerobic exercise to get the ideal outcome.
✗ Aerobic exercise may not be as efficient as other exercise
methods for eliciting the same improvements in body
composition, cardiovascular health, and overall health. For
example, HIIT (high-intensity interval training) exercise
has been shown to provide the same benefits in a fraction of
the time spent exercising per week