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Chapter 1

Exploring Life

PowerPoint Lectures for
Biology, Seventh Edition
Neil Campbell and Jane Reece

Lectures by Chris Romero
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Overview: Biology’s Most Exciting Era
• Biology
– Is the scientific study of life

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• The phenomenon we call life
– Defies a simple, one-sentence definition

Figure 1.1
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• We recognize life
– By what living things do

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Some properties of life

(a) Order

(d) Regulation

(b) Evolutionary
adaptation
(c) Response to the
environment

(e) Energy
processing

(f) Growth and
development

Figure 1.2
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

(g) Reproduction
• Concept 1.1: Biologists explore life from the
microscopic to the global scale
• The study of life
– Extends from the microscope scale of
molecules and cells to the global scale of the
entire living planet

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
A Hierarchy of Biological Organization
• The hierarchy of life
– Extends through many levels of biological
organization

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• From the biosphere to organisms
1 The biosphere

Figure 1.3
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• From cells to molecules
9 Organelles
1 µm

Cell

8 Cells

Atoms

10 µm

7 Tissues
50 µm

6 Organs and organ systems
Figure 1.3
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

10 Molecules
A Closer Look at Ecosystems
• Each organism
– Interacts with its environment

• Both organism and environment
– Are affected by the interactions between them

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Ecosystem Dynamics
• The dynamics of any ecosystem include two
major processes
– Cycling of nutrients, in which materials
acquired by plants eventually return to the soil
– The flow of energy from sunlight to producers
to consumers

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Energy Conversion
• Activities of life
– Require organisms to perform work, which
depends on an energy source

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• The exchange of energy between an organism
and its surroundings
– Often involves the transformation of one form
of energy to another

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Energy flows through an ecosystem
– Usually entering as sunlight and exiting as
heat
Sunlight
Ecosystem

Producers
(plants and other
photosynthetic
organisms)
Heat
Chemical
energy

Consumers
(including animals)

Figure 1.4
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

Heat
A Closer Look at Cells
• The cell
– Is the lowest level of organization that can
perform all activities required for life

Figure 1.5
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

25 µm
The Cell’s Heritable Information
• Cells contain chromosomes made partly of
DNA, the substance of genes
– Which program the cells’ production of proteins
and transmit information from parents to
offspring
Sperm cell
Nuclei
containing
DNA

Egg cell

Fertilized egg
with DNA from
both parents

Figure 1.6
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

Embyro’s cells
with copies of
inherited DNA

Offspring with traits
inherited from
both parents
• The molecular structure of DNA
– Accounts for it information-rich nature
Nucleus
DNA
Cell
Nucleotide

(a) DNA double helix. This model shows
each atom in a segment of DNA.Made
up of two long chains of building
blocks called nucleotides, a DNA
Figure 1.7
molecule takes the three-dimensional
form of a double helix.
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

A
C
T
A
T
A
C
C
G
T
A
G
T
A

(b) Single strand of DNA. These geometric shapes and
letters are simple symbols for the nucleotides in a
small section of one chain of a DNA molecule.
Genetic information is encoded in specific sequences
of the four types of nucleotides (their names are
abbreviated here as A, T, C, and G).
Two Main Forms of Cells
• All cells share certain characteristics
– They are all enclosed by a membrane
– They all use DNA as genetic information

• There are two main forms of cells
– Eukaryotic
– Prokaryotic

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Eukaryotic cells
–

Are subdivided by internal membranes into various membraneenclosed organelles

• Prokaryotic cells
–

Lack the kinds of membrane-enclosed organelles found in
eukaryotic cells
EUKARYOTIC CELL
PROKARYOTIC CELL
Membrane
Cytoplasm

Figure 1.8

Organelles
Nucleus (contains DNA)

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

DNA
(no nucleus)
Membrane

1 µm
• Concept 1.2: Biological systems are much
more than the sum of their parts
• A system
– Is a combination of components that form a
more complex organization

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
The Emergent Properties of Systems
• Due to increasing complexity
– New properties emerge with each step upward
in the hierarchy of biological order

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
The Power and Limitations of Reductionism
• Reductionism
– Involves reducing complex systems to simpler
components that are more manageable to
study

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• The study of DNA structure, an example of
reductionism
– Has led to further study of heredity, such as
the Human Genome Project

Figure 1.9
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Systems Biology
• Systems biology
– Seeks to create models of the dynamic
behavior of whole biological systems

• With such models
– Scientists will be able to predict how a change
in one part of a system will affect the rest of
the system

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Outer membrane
and cell surface

CELL

Cytoplasm
Nucleu
s

Figure 1.10
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Systems biology
– Is now taking hold in the study of life at the
cellular and molecular levels
– Includes three key research developments:
high-throughput technology, bioinformatics,
and interdisciplinary research teams

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Feedback Regulation in Biological Systems
• A kind of supply-and-demand economy
– Applies to some of the dynamics of biological
systems

• In feedback regulation
– The output, or product, of a process regulates
that very process

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• In negative feedback
– An accumulation of an end product slows the
process that produces that product
A

Negative
feedback

Enzyme 1
B

A
Enzyme 1
B

Enzyme 2
C

C
Enzyme 3

D
D

D
D

D

D

D

D
D

D

Figure 1.11
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

D
• In positive feedback
– The end product speeds up production
W

W
Enzyme 4

Enzyme 4
Positive
feedback

X

X

Enzyme 5

Enzyme 5

Y

Y
Enzyme 6

Z

Z

Z
Z

Figure 1.12

Enzyme 6
Z

Z

Z
Z

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

Z

Z

Z

Z
Z

Z

Z

Z

Z
Z

Z
• Concept 1.3: Biologists explore life across its
great diversity of species
• Diversity is a hallmark of life

Figure 1.13
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Grouping Species: The Basic Idea
• Taxonomy
– Is the branch of biology that names and
classifies species according to a system of
broader and broader groups

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Classifying life
Species Genus Family

Order

Class

Phylum

Ursus
americanus
(American
black bear)
Ursus

Ursidae

Carnivora

Mammalia

Chordata

Animalia

Figure 1.14
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

Eukarya

Kingdom

Domain
The Three Domains of Life
• At the highest level, life is classified into three
domains
– Bacteria
– Archaea
– Eukarya

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Domain Bacteria and domain Archaea
– Consist of prokaryotes

• Domain Eukarya, the eukaryotes
– Includes the various protist kingdoms and the
kingdoms Plantae, Fungi, and Animalia

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Life’s three domains

Bacteria are the most diverse
4 µm
and widespread prokaryotes
and are now divided among multiple
kingdoms. Each of the rod-shaped
structures in this photo is a bacterial cell.

DOMAIN ARCHAEA

Figure 1.15

Many of the prokaryotes known
0.5 µm
as archaea live in Earth‘s
extreme environments, such as salty lakes
and boiling hot springs. Domain Archaea
includes multiple kingdoms. The photo
shows a colony composed of many cells.

Protists (multiple kingdoms)
100 µm
are unicellular eukaryotes and
their relatively simple multicellular
relatives.Pictured here is an assortment of
protists inhabiting pond water. Scientists are
currently debating how to split the protists
into several kingdoms that better represent
evolution and diversity.

Kingdom Plantae consists of
multicellula eukaryotes that carry
out photosynthesis, the conversion
of light energy to food.

Kindom Fungi is defined in part by the
nutritional mode of its members, such
as this mushroom, which absorb
nutrientsafter decomposing organic
material.

Kindom Animalia consists of
multicellular eukaryotes that
ingest other organisms.

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Unity in the Diversity of Life
• As diverse as life is
– There is also evidence of remarkable unity
15 µm

1.0 µm

Cilia of Paramecium.
The cilia of Paramecium
propel the cell through
pond water.
5 µm

Figure 1.16

Cross section of cilium, as viewed
with an electron microscope

Cilia of windpipe cells. The cells that line the human windpipe
are equipped with cilia that help keep the lungs clean by moving
a film of debris-trapping mucus upward.

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Concept 1.4: Evolution accounts for life’s unity and
diversity
• The history of life
– Is a saga of a changing Earth billions of years old

Figure 1.17
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• The evolutionary view of life
– Came into sharp focus in 1859 when Charles
Darwin published On the Origin of Species by
Natural Selection

Figure 1.18
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• The Origin of Species articulated two main
points
– Descent with modification
– Natural selection

Figure 1.19
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Natural Selection
• Darwin proposed natural selection
– As the mechanism for evolutionary adaptation
of populations to their environments
Population
of organisms

Hereditary
variations

Overproduction
and struggle for
existence

Differences in
reproductive success

Figure 1.20

Evolution of adaptations
in the population

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Natural selection is the evolutionary process that
occurs
– When a population’s heritable variations are exposed
to environmental factors that favor the reproductive
success of some individuals over others
1

Populations with varied inherited traits

2 Elimination of individuals with certain traits.

3 Reproduction of survivors.

Figure 1.21

4 Increasing frequency of traits that enhance
survival and reproductive success.

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• The products of natural selection
– Are often exquisite adaptations of organisms to
the special circumstances of their way of life
and their environment

Figure 1.22
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
The Tree of Life
• Many related organisms
– Have very similar anatomical features, adapted
for their specific ways of life

• Such examples of kinship
– Connect life’s “unity in diversity” to Darwin’s
concept of “descent with modification”

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Darwin proposed that natural selection
– Could enable an ancestral species to “split” into two or
more descendant species, resulting in a “tree of life”
Large
ground finch
Large cactus
ground finch

Small
ground
finch

Large
tree finch

Geospiza
Camarhynchus
Green
Gray
Geospiza
magnirostris
psitacula Medium
warbler warbler
Sharp-beaked
fuliginosa
Woodpecker
Geospiza Medium
finch
tree finch
finch
ground finch
finch
ground
conirostris
finch
Certhidea Certhidea
GeospizaCactus
Cactospiza Camarhynchus
olivacea fusca
pauper
difficilis ground finch
pallida
Geospiza Mangrove
Small tree finch
finch
fortis
Geospiza
Camarhynchus
Cactospiza
scandens
parvulus
heliobates
Vegetarian
Cactus flower
Seed eater
Seed eater
finch
eater
Platyspiza
crassirostris
Insect eaters
Ground finches

Figure 1.23
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

Tree finches

Bud eater
Warbler finches

Common ancestor from
South American mainland
• Each species is on twig of a branching tree of
life
– Extending back in time through ancestral
species more and more remote

• All of life
– Is connected through its long evolutionary
history

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Concept 1.5: Biologists use various forms of
inquiry to explore life
• At the heart of science is inquiry
– A search for information and explanation, often
focusing on specific questions

• Biology blends two main processes of scientific
inquiry
– Discovery science
– Hypothesis-based science
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Discovery Science
• Discovery science
– Describes natural structures and processes as
accurately as possible through careful
observation and analysis of data

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Types of Data
• Data
– Are recorded observations
– Can be quantitative or qualitative

Figure 1.24
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Induction in Discovery Science
• In inductive reasoning
– Scientists derive generalizations based on a
large number of specific observations

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Hypothesis-Based Science
• In science, inquiry that asks specific questions
– Usually involves the proposing and testing of
hypothetical explanations, or hypotheses

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
The Role of Hypotheses in Inquiry
• In science, a hypothesis
– Is a tentative answer to a well-framed
question, an explanation on trial
– Makes predictions that can be tested

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• We all use hypotheses in solving everyday
problems
Observations

Questions
Hypothesis # 1:
Dead batteries
Prediction:
Replacing batteries
will fix problem

Test prediction

Figure 1.25

Test falsifies hypothesis

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

Hypothesis # 2:
Burnt-out bulb
Prediction:
Replacing bulb
will fix problem

Test prediction

Test does not falsify hypothesis
Deduction: The “If…then” Logic of Hypothesis-Based Science

• In deductive reasoning
– The logic flows from the general to the specific

• If a hypothesis is correct
– Then we can expect a particular outcome

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
A Closer Look at Hypotheses in Scientific Inquiry
• A scientific hypothesis must have two important
qualities
– It must be testable
– It must be falsifiable

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
The Myth of the Scientific Method
• The scientific method
– Is an idealized process of inquiry

• Very few scientific inquiries
– Adhere to the “textbook” scientific method

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
A Case Study in Scientific Inquiry: Investigating
Mimicry in Snake Populations

• In mimicry
– A harmless species resembles a harmful
species
Flower fly
(non-stinging)

Honeybee (stinging)
Figure 1.26
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• In this case study
– Mimicry in king snakes is examined
– The hypothesis predicts that predators in non–coral
snake areas will attack king snakes more frequently
than will predators that live where coral snakes are
present
Scarlet king snake
Key
Range of scarlet king snake
Range of eastern color snake

North
Carolina

South
Carolina

Eastern coral snake

Figure 1.27

Scarlet king snake

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Field Experiments with Artificial Snakes
• To test this mimicry hypothesis
– Researchers made hundreds of artificial snakes, an
experimental group resembling king snakes and a
control group of plain brown snakes

(a) Artificial king snake

Figure 1.28

(b) Brown artificial snake that has been attacked

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• After a given period of time
– The researchers collected data that fit a key
Key
Key
prediction
% of attacks on artificial king snakes

% of attacks on brown artificial snakes
Field site with artificial snakes
17%

In areas where coral snakes
were absent, most attacks
were on artificial king snakes

83%

X
XX
North
Carolina X
XX
South
X
Carolina X
X
XX

X
XX

16%

84%

Figure 1.29
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

In areas where coral
snakes were present,
most attacks were on
artificial king snakes
Designing Controlled Experiments
• Experiments must be designed to test
– The effect of one variable by testing control
groups and experimental groups in a way that
cancels the effects of unwanted variables

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Limitations of Science
• Science cannot address supernatural
phenomena
– Because hypotheses must be testable and
falsifiable and experimental results must be
repeatable

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Theories in Science
• A scientific theory
– Is broad in scope
– Generates new hypotheses
– Is supported by a large body of evidence

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Model Building in Science
• Models of ideas, structures, and processes
– Help us understand scientific phenomena and
From
From
make predictions
body

Right
artium

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

Right
artium

Right
ventricle

Figure 1.30

lungs

Right
ventricle

To lungs

To body
The Culture of Science
• Science is a social activity
– Characterized by both cooperation and
competition

Figure 1.31
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
Science, Technology, and Society
• Technology
– Applies scientific knowledge for some specific
purpose

Figure 1.32
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Concept 1.6: A set of themes connects the
concepts of biology
• Underlying themes
– Provide a framework for understanding biology

Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
• Eleven themes that unify biology

Table 1.1
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings

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Chapter1-Exploring Life

  • 1. Chapter 1 Exploring Life PowerPoint Lectures for Biology, Seventh Edition Neil Campbell and Jane Reece Lectures by Chris Romero Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 2. • Overview: Biology’s Most Exciting Era • Biology – Is the scientific study of life Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 3. • The phenomenon we call life – Defies a simple, one-sentence definition Figure 1.1 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 4. • We recognize life – By what living things do Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 5. • Some properties of life (a) Order (d) Regulation (b) Evolutionary adaptation (c) Response to the environment (e) Energy processing (f) Growth and development Figure 1.2 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings (g) Reproduction
  • 6. • Concept 1.1: Biologists explore life from the microscopic to the global scale • The study of life – Extends from the microscope scale of molecules and cells to the global scale of the entire living planet Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 7. A Hierarchy of Biological Organization • The hierarchy of life – Extends through many levels of biological organization Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 8. • From the biosphere to organisms 1 The biosphere Figure 1.3 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 9. • From cells to molecules 9 Organelles 1 µm Cell 8 Cells Atoms 10 µm 7 Tissues 50 µm 6 Organs and organ systems Figure 1.3 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings 10 Molecules
  • 10. A Closer Look at Ecosystems • Each organism – Interacts with its environment • Both organism and environment – Are affected by the interactions between them Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 11. Ecosystem Dynamics • The dynamics of any ecosystem include two major processes – Cycling of nutrients, in which materials acquired by plants eventually return to the soil – The flow of energy from sunlight to producers to consumers Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 12. Energy Conversion • Activities of life – Require organisms to perform work, which depends on an energy source Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 13. • The exchange of energy between an organism and its surroundings – Often involves the transformation of one form of energy to another Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 14. • Energy flows through an ecosystem – Usually entering as sunlight and exiting as heat Sunlight Ecosystem Producers (plants and other photosynthetic organisms) Heat Chemical energy Consumers (including animals) Figure 1.4 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Heat
  • 15. A Closer Look at Cells • The cell – Is the lowest level of organization that can perform all activities required for life Figure 1.5 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings 25 µm
  • 16. The Cell’s Heritable Information • Cells contain chromosomes made partly of DNA, the substance of genes – Which program the cells’ production of proteins and transmit information from parents to offspring Sperm cell Nuclei containing DNA Egg cell Fertilized egg with DNA from both parents Figure 1.6 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Embyro’s cells with copies of inherited DNA Offspring with traits inherited from both parents
  • 17. • The molecular structure of DNA – Accounts for it information-rich nature Nucleus DNA Cell Nucleotide (a) DNA double helix. This model shows each atom in a segment of DNA.Made up of two long chains of building blocks called nucleotides, a DNA Figure 1.7 molecule takes the three-dimensional form of a double helix. Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings A C T A T A C C G T A G T A (b) Single strand of DNA. These geometric shapes and letters are simple symbols for the nucleotides in a small section of one chain of a DNA molecule. Genetic information is encoded in specific sequences of the four types of nucleotides (their names are abbreviated here as A, T, C, and G).
  • 18. Two Main Forms of Cells • All cells share certain characteristics – They are all enclosed by a membrane – They all use DNA as genetic information • There are two main forms of cells – Eukaryotic – Prokaryotic Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 19. • Eukaryotic cells – Are subdivided by internal membranes into various membraneenclosed organelles • Prokaryotic cells – Lack the kinds of membrane-enclosed organelles found in eukaryotic cells EUKARYOTIC CELL PROKARYOTIC CELL Membrane Cytoplasm Figure 1.8 Organelles Nucleus (contains DNA) Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings DNA (no nucleus) Membrane 1 µm
  • 20. • Concept 1.2: Biological systems are much more than the sum of their parts • A system – Is a combination of components that form a more complex organization Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 21. The Emergent Properties of Systems • Due to increasing complexity – New properties emerge with each step upward in the hierarchy of biological order Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 22. The Power and Limitations of Reductionism • Reductionism – Involves reducing complex systems to simpler components that are more manageable to study Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 23. • The study of DNA structure, an example of reductionism – Has led to further study of heredity, such as the Human Genome Project Figure 1.9 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 24. Systems Biology • Systems biology – Seeks to create models of the dynamic behavior of whole biological systems • With such models – Scientists will be able to predict how a change in one part of a system will affect the rest of the system Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 25. Outer membrane and cell surface CELL Cytoplasm Nucleu s Figure 1.10 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 26. • Systems biology – Is now taking hold in the study of life at the cellular and molecular levels – Includes three key research developments: high-throughput technology, bioinformatics, and interdisciplinary research teams Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 27. Feedback Regulation in Biological Systems • A kind of supply-and-demand economy – Applies to some of the dynamics of biological systems • In feedback regulation – The output, or product, of a process regulates that very process Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 28. • In negative feedback – An accumulation of an end product slows the process that produces that product A Negative feedback Enzyme 1 B A Enzyme 1 B Enzyme 2 C C Enzyme 3 D D D D D D D D D D Figure 1.11 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings D
  • 29. • In positive feedback – The end product speeds up production W W Enzyme 4 Enzyme 4 Positive feedback X X Enzyme 5 Enzyme 5 Y Y Enzyme 6 Z Z Z Z Figure 1.12 Enzyme 6 Z Z Z Z Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Z Z Z Z Z Z Z Z Z Z Z
  • 30. • Concept 1.3: Biologists explore life across its great diversity of species • Diversity is a hallmark of life Figure 1.13 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 31. Grouping Species: The Basic Idea • Taxonomy – Is the branch of biology that names and classifies species according to a system of broader and broader groups Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 32. • Classifying life Species Genus Family Order Class Phylum Ursus americanus (American black bear) Ursus Ursidae Carnivora Mammalia Chordata Animalia Figure 1.14 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Eukarya Kingdom Domain
  • 33. The Three Domains of Life • At the highest level, life is classified into three domains – Bacteria – Archaea – Eukarya Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 34. • Domain Bacteria and domain Archaea – Consist of prokaryotes • Domain Eukarya, the eukaryotes – Includes the various protist kingdoms and the kingdoms Plantae, Fungi, and Animalia Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 35. • Life’s three domains Bacteria are the most diverse 4 µm and widespread prokaryotes and are now divided among multiple kingdoms. Each of the rod-shaped structures in this photo is a bacterial cell. DOMAIN ARCHAEA Figure 1.15 Many of the prokaryotes known 0.5 µm as archaea live in Earth‘s extreme environments, such as salty lakes and boiling hot springs. Domain Archaea includes multiple kingdoms. The photo shows a colony composed of many cells. Protists (multiple kingdoms) 100 µm are unicellular eukaryotes and their relatively simple multicellular relatives.Pictured here is an assortment of protists inhabiting pond water. Scientists are currently debating how to split the protists into several kingdoms that better represent evolution and diversity. Kingdom Plantae consists of multicellula eukaryotes that carry out photosynthesis, the conversion of light energy to food. Kindom Fungi is defined in part by the nutritional mode of its members, such as this mushroom, which absorb nutrientsafter decomposing organic material. Kindom Animalia consists of multicellular eukaryotes that ingest other organisms. Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 36. Unity in the Diversity of Life • As diverse as life is – There is also evidence of remarkable unity 15 µm 1.0 µm Cilia of Paramecium. The cilia of Paramecium propel the cell through pond water. 5 µm Figure 1.16 Cross section of cilium, as viewed with an electron microscope Cilia of windpipe cells. The cells that line the human windpipe are equipped with cilia that help keep the lungs clean by moving a film of debris-trapping mucus upward. Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 37. • Concept 1.4: Evolution accounts for life’s unity and diversity • The history of life – Is a saga of a changing Earth billions of years old Figure 1.17 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 38. • The evolutionary view of life – Came into sharp focus in 1859 when Charles Darwin published On the Origin of Species by Natural Selection Figure 1.18 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 39. • The Origin of Species articulated two main points – Descent with modification – Natural selection Figure 1.19 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 40. Natural Selection • Darwin proposed natural selection – As the mechanism for evolutionary adaptation of populations to their environments Population of organisms Hereditary variations Overproduction and struggle for existence Differences in reproductive success Figure 1.20 Evolution of adaptations in the population Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 41. • Natural selection is the evolutionary process that occurs – When a population’s heritable variations are exposed to environmental factors that favor the reproductive success of some individuals over others 1 Populations with varied inherited traits 2 Elimination of individuals with certain traits. 3 Reproduction of survivors. Figure 1.21 4 Increasing frequency of traits that enhance survival and reproductive success. Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 42. • The products of natural selection – Are often exquisite adaptations of organisms to the special circumstances of their way of life and their environment Figure 1.22 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 43. The Tree of Life • Many related organisms – Have very similar anatomical features, adapted for their specific ways of life • Such examples of kinship – Connect life’s “unity in diversity” to Darwin’s concept of “descent with modification” Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 44. • Darwin proposed that natural selection – Could enable an ancestral species to “split” into two or more descendant species, resulting in a “tree of life” Large ground finch Large cactus ground finch Small ground finch Large tree finch Geospiza Camarhynchus Green Gray Geospiza magnirostris psitacula Medium warbler warbler Sharp-beaked fuliginosa Woodpecker Geospiza Medium finch tree finch finch ground finch finch ground conirostris finch Certhidea Certhidea GeospizaCactus Cactospiza Camarhynchus olivacea fusca pauper difficilis ground finch pallida Geospiza Mangrove Small tree finch finch fortis Geospiza Camarhynchus Cactospiza scandens parvulus heliobates Vegetarian Cactus flower Seed eater Seed eater finch eater Platyspiza crassirostris Insect eaters Ground finches Figure 1.23 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Tree finches Bud eater Warbler finches Common ancestor from South American mainland
  • 45. • Each species is on twig of a branching tree of life – Extending back in time through ancestral species more and more remote • All of life – Is connected through its long evolutionary history Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 46. • Concept 1.5: Biologists use various forms of inquiry to explore life • At the heart of science is inquiry – A search for information and explanation, often focusing on specific questions • Biology blends two main processes of scientific inquiry – Discovery science – Hypothesis-based science Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 47. Discovery Science • Discovery science – Describes natural structures and processes as accurately as possible through careful observation and analysis of data Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 48. Types of Data • Data – Are recorded observations – Can be quantitative or qualitative Figure 1.24 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 49. Induction in Discovery Science • In inductive reasoning – Scientists derive generalizations based on a large number of specific observations Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 50. Hypothesis-Based Science • In science, inquiry that asks specific questions – Usually involves the proposing and testing of hypothetical explanations, or hypotheses Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 51. The Role of Hypotheses in Inquiry • In science, a hypothesis – Is a tentative answer to a well-framed question, an explanation on trial – Makes predictions that can be tested Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 52. • We all use hypotheses in solving everyday problems Observations Questions Hypothesis # 1: Dead batteries Prediction: Replacing batteries will fix problem Test prediction Figure 1.25 Test falsifies hypothesis Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Hypothesis # 2: Burnt-out bulb Prediction: Replacing bulb will fix problem Test prediction Test does not falsify hypothesis
  • 53. Deduction: The “If…then” Logic of Hypothesis-Based Science • In deductive reasoning – The logic flows from the general to the specific • If a hypothesis is correct – Then we can expect a particular outcome Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 54. A Closer Look at Hypotheses in Scientific Inquiry • A scientific hypothesis must have two important qualities – It must be testable – It must be falsifiable Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 55. The Myth of the Scientific Method • The scientific method – Is an idealized process of inquiry • Very few scientific inquiries – Adhere to the “textbook” scientific method Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 56. A Case Study in Scientific Inquiry: Investigating Mimicry in Snake Populations • In mimicry – A harmless species resembles a harmful species Flower fly (non-stinging) Honeybee (stinging) Figure 1.26 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 57. • In this case study – Mimicry in king snakes is examined – The hypothesis predicts that predators in non–coral snake areas will attack king snakes more frequently than will predators that live where coral snakes are present Scarlet king snake Key Range of scarlet king snake Range of eastern color snake North Carolina South Carolina Eastern coral snake Figure 1.27 Scarlet king snake Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 58. Field Experiments with Artificial Snakes • To test this mimicry hypothesis – Researchers made hundreds of artificial snakes, an experimental group resembling king snakes and a control group of plain brown snakes (a) Artificial king snake Figure 1.28 (b) Brown artificial snake that has been attacked Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 59. • After a given period of time – The researchers collected data that fit a key Key Key prediction % of attacks on artificial king snakes % of attacks on brown artificial snakes Field site with artificial snakes 17% In areas where coral snakes were absent, most attacks were on artificial king snakes 83% X XX North Carolina X XX South X Carolina X X XX X XX 16% 84% Figure 1.29 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings In areas where coral snakes were present, most attacks were on artificial king snakes
  • 60. Designing Controlled Experiments • Experiments must be designed to test – The effect of one variable by testing control groups and experimental groups in a way that cancels the effects of unwanted variables Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 61. Limitations of Science • Science cannot address supernatural phenomena – Because hypotheses must be testable and falsifiable and experimental results must be repeatable Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 62. Theories in Science • A scientific theory – Is broad in scope – Generates new hypotheses – Is supported by a large body of evidence Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 63. Model Building in Science • Models of ideas, structures, and processes – Help us understand scientific phenomena and From From make predictions body Right artium Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings Right artium Right ventricle Figure 1.30 lungs Right ventricle To lungs To body
  • 64. The Culture of Science • Science is a social activity – Characterized by both cooperation and competition Figure 1.31 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 65. Science, Technology, and Society • Technology – Applies scientific knowledge for some specific purpose Figure 1.32 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 66. • Concept 1.6: A set of themes connects the concepts of biology • Underlying themes – Provide a framework for understanding biology Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings
  • 67. • Eleven themes that unify biology Table 1.1 Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings