Human heredity is determined by chromosomes, which are structures in the nucleus that contain genetic information passed down between generations. A karyotype maps out a person's entire set of chromosomes and can be used to identify genetic disorders. Traits are transmitted through dominant and recessive alleles, codominant alleles, sex-linked inheritance, and X chromosome inactivation. Common genetic disorders include sickle cell disease, cystic fibrosis, and Huntington's disease, which result from changes in single genes. Some genetic mutations can provide advantages, like resistance to malaria. The human genome project worked to sequence and identify all human genes to further understand genetic inheritance and open up possibilities for new treatments.