Pharmacists must provide a clear and compelling description of the product or service that they are marketing. This is crucial for business and marketing communication plans
A summary of macro level trends and issues that are driving the need for enhanced digital marketing and service delivery in the Pharma/Healthcare industry. Included are case studies presented at the recent ePharm Summit in NYC.
Pharmaceutical Branding: Therapeutic Franchise / Range Brand ModelDavid Delong
The traditional pharmaceutical branding model is flawed strategically, tactically and financially. In this presentation we review the different branding models available to pharma with a focus on the disadvantages of the current pharma Brand as Product model
Budget Allocation for a Successful Bio-Pharma Product LaunchBest Practices
Bio-Pharma companies can no longer afford to rely solely on past experiences when budgeting for a new product launch in today's fast-changing, highly competitive market. This comprehensive benchmark study by Best Practices, LLC investigates current costs as well as budget and staffing allocations required for a successful drug launch.
This study can help bio-pharma leaders to develop competitive launch and pre-launch activity budgets to ensure successful U.S. market entry for new products.
Download Full Report: http://bit.ly/2aMYron
Pharmacists must provide a clear and compelling description of the product or service that they are marketing. This is crucial for business and marketing communication plans
A summary of macro level trends and issues that are driving the need for enhanced digital marketing and service delivery in the Pharma/Healthcare industry. Included are case studies presented at the recent ePharm Summit in NYC.
Pharmaceutical Branding: Therapeutic Franchise / Range Brand ModelDavid Delong
The traditional pharmaceutical branding model is flawed strategically, tactically and financially. In this presentation we review the different branding models available to pharma with a focus on the disadvantages of the current pharma Brand as Product model
Budget Allocation for a Successful Bio-Pharma Product LaunchBest Practices
Bio-Pharma companies can no longer afford to rely solely on past experiences when budgeting for a new product launch in today's fast-changing, highly competitive market. This comprehensive benchmark study by Best Practices, LLC investigates current costs as well as budget and staffing allocations required for a successful drug launch.
This study can help bio-pharma leaders to develop competitive launch and pre-launch activity budgets to ensure successful U.S. market entry for new products.
Download Full Report: http://bit.ly/2aMYron
The basics of launching a pharmaceutical drug-
Based on studies done on the practices of 13 top pharmaceutical companies in the world.
For more, write to info@markivmedical.com
New Pharma approach: from (e-)detailing to customer & patients excellence: a ...A.R.J. (Rob) Halkes
In the demand for a new business model for pharma, the roadmap from current promotion via detailing to a more engaging way to physicians and health care providers, may lead stepwise to improved servicing to physicians and may lead to collaboration to co-create patient care. Role of social media to pharma and multichannel approaches may so find its position in new pharma marketing.
New Product Planning in the Pharmaceutical IndustryAnthony Russell
Lecture presented in the Competitive Intelligence and Pricing course as part of the University of Southern California Master of Science in Healthcare Decision Analysis program. Presented on June 14, 2020 at USC via Zoom. The lectures gives an overview of what new product planning is in the pharmaceutical industry, what tools are used during new product evaluations, and the key elements of a new product business case. The lecture includes a couple of case studies to be worked on by the class.
This presentation is designed to help pharmacy students identify business ideas and innovations. This helps when building business plans and business models.
How Many Types of Marketing Strategies in Pharma Sector? - Ambit Bio Medixambitbiomedix12
If you are looking to many types of Marketing Strategies in Pharma Sector then Ambit Bio Medix is one of best top 10 pharma franchise companies at the best price. Here are the Many Types of Marketing Strategies in Pharma Sector.
“Marketing 2.0” in the pharmaceutical industry is no longer about just saying that our product is different and hoping customers will see it that way. It’s very much about making it so and then about finding our way to engage customers in a “conversation” that helps create the value rather than just promoting it through armies of medical representatives. We need to develop new, end-to-end processes that shape our relationships with physicians, payers, patients and care-givers.
This pitch deck is used to give immediate feedback to ideas for business models. It allows pharmacists and students to describe the basics of their ideas to get feedback on its potential for success.
Educators can use it to teach students how to present business models.
Good service design can be a source of competitive advantage for pharmacists. This presentation describes how pharmacists can design better service experiences for patients.
The basics of launching a pharmaceutical drug-
Based on studies done on the practices of 13 top pharmaceutical companies in the world.
For more, write to info@markivmedical.com
New Pharma approach: from (e-)detailing to customer & patients excellence: a ...A.R.J. (Rob) Halkes
In the demand for a new business model for pharma, the roadmap from current promotion via detailing to a more engaging way to physicians and health care providers, may lead stepwise to improved servicing to physicians and may lead to collaboration to co-create patient care. Role of social media to pharma and multichannel approaches may so find its position in new pharma marketing.
New Product Planning in the Pharmaceutical IndustryAnthony Russell
Lecture presented in the Competitive Intelligence and Pricing course as part of the University of Southern California Master of Science in Healthcare Decision Analysis program. Presented on June 14, 2020 at USC via Zoom. The lectures gives an overview of what new product planning is in the pharmaceutical industry, what tools are used during new product evaluations, and the key elements of a new product business case. The lecture includes a couple of case studies to be worked on by the class.
This presentation is designed to help pharmacy students identify business ideas and innovations. This helps when building business plans and business models.
How Many Types of Marketing Strategies in Pharma Sector? - Ambit Bio Medixambitbiomedix12
If you are looking to many types of Marketing Strategies in Pharma Sector then Ambit Bio Medix is one of best top 10 pharma franchise companies at the best price. Here are the Many Types of Marketing Strategies in Pharma Sector.
“Marketing 2.0” in the pharmaceutical industry is no longer about just saying that our product is different and hoping customers will see it that way. It’s very much about making it so and then about finding our way to engage customers in a “conversation” that helps create the value rather than just promoting it through armies of medical representatives. We need to develop new, end-to-end processes that shape our relationships with physicians, payers, patients and care-givers.
This pitch deck is used to give immediate feedback to ideas for business models. It allows pharmacists and students to describe the basics of their ideas to get feedback on its potential for success.
Educators can use it to teach students how to present business models.
Good service design can be a source of competitive advantage for pharmacists. This presentation describes how pharmacists can design better service experiences for patients.
This answers questions about why customers behave the way they do in in pharmacy settings. Although it might appear irrational at times, they act in ways that are consistent with consumer behavior theories.
This presentation discusses how patients perceive pharmacy services. It discusses how satisfaction, loyalty, service quality, and price influence customer perceptions of the care they receive.
This presentation describes the elements of good pharmacist services and the consequences of poor service. Good pharmacy services do not just happen. They are the result of hard work.
Patients' Perceptions of Community Pharmacy Practice in UAE: An Overviewiosrphr_editor
The IOSR Journal of Pharmacy (IOSRPHR) is an open access online & offline peer reviewed international journal, which publishes innovative research papers, reviews, mini-reviews, short communications and notes dealing with Pharmaceutical Sciences( Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy & Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest........more details on Aim & Scope).
Rebecca Cheng, BPharm, RegPharmNZ, MRPharmS
Pharmacy Guild of New Zealand
(Thursday, 1.30, Innovation in Practice 1)
Medicines Control (a division of the Ministry of Health) requires all pharmacies to have a complete set of standard operating procedures (SOPs) to fulfil their Quality Audit requirements. The SOPs can range from dispensing a medicine, through to cleaning the fridge. There are currently over 100 SOPs that pharmacies must have in order to comply with the Medicines Control audit requirements. The Pharmacy Guild of New Zealand (Inc) (the Guild) has developed an electronic programme together with template SOPs to help pharmacies comply with the Quality Audit requirements. The new service – GuildLink® - is available to pharmacies on a subscription basis and is designed to manage and improve quality within community pharmacy practice.
This presentation describes how pharmacists and pharmacies can innovate when delivering professional services. Goes beyond one-stop-shopping and low price services.
Basic promotional strategies are presented for pharmacists who want to communicate with patients and customers. Theories and practices of marketing communications are presented.
This presentation describes why it is so hard to market pharmacist services. It presents services marketing techniques to help communicate the value of health care.
This presentation defines what is a Business Model and illustrates them using a Business Model Canvas. It identifies generic business models that are common in community pharmacies and provides examples.
these slides gives depth knowledge regarding consumer behavior. Marketing manager and students of Marketing can increase their knowledge regarding this aspect.
Price dominates shoppers' buying decisions - making it critical for retailers to get prices right from the start. Today, pricing has moved from an art to a science - compelling retailers to manage it as a dedicated, technology-driven area of their business.
This document reviews best practice in pricing processes to provide a reference against which current practices and proposals can be tested. Our objectives have been: to research the attributes of world-class pricing through publications and academic sources; to investigate how these attributes are applied in practice to products and services; to assess pricing processes in successful businesses.
In recent years a new attitude toward pricing has emerged. Deregulation and international free trade agreements have increased competition. Price promotion has eroded the power of brand loyalty. Pricing has assumed greater importance to most businesses.
As markets increasingly assume a global dimension, customers can more easily compare prices between one region or country and another, using the internet or a fax machine. They can often locate the same product, or an
acceptable substitute, from another source. Customers are more demanding and fickle, and their expectations increasingly difficult to fulfil.
Price inflation in western economies is now at its lowest for decades. Price increases are no longer accepted without protest from customers, if at all.
The Chairman of General Electric has predicted the onset of the ‘Value Decade’. Global price competition will strengthen because of: reduced product differentiation; global over-capacity for production; significantly diminished trade barriers; efficient information and distribution systems; providing customers with easy access to the prices of suppliers; a growing lack of customers’ loyalty to individual suppliers. Choice will be increasingly driven by price.
This is a challenging scenario that reinforces the need for an integrated strategy and concerted managerial action on pricing.
Pricing processes have lagged behind developments in the market place. They are often characterised by internal conflict between accountants wishing to maximise profit per unit and marketing specialists who seek to maximise
throughput. They are also affected by the potential for strained relations with good customers.
Some companies have downsized their operations to a level where diminishing returns cause them to question the benefits of continuing to focus upon reducing costs. As they switch their attention from cost cutting to adding
value, pricing naturally assumes increased weight in the marketing mix.
We have found many companies reluctant to discuss their own processes.
Some may wish to avoid betraying a lack of sophistication.
65% of executives believe that they are not able to charge the prices they deserve for their products and services *
46% of companies believe they are involved in price wars. In some countries, such as Japan that figure is as high as 85% *
Why are so many companies failing to achieve prices for their products and services that reflect the true value they provide to customers? In our experience, with hi tech, energy and healthcare clients, failure to achieve value pricing is due to lack of preparation, communication capabilities and negotiation skills of the sales people.
What you will learn:
- Dynamics between price discounts and profitability.
- Quantifying and communicating the impact of the offer value to justify a fair price.
- Identifying the specific buyers who recognize the importance a good value offering.
- Circumventing price-only procurement buyers without alienating them.
* 'Global Pricing Study 2011: "Weak pricing cuts profits by 25%"'. Simon – Kucher. August 2011.
MBA 5501, Advanced Marketing 1 Course Learning Outcom.docxaryan532920
MBA 5501, Advanced Marketing 1
Course Learning Outcomes for Unit VI
Upon completion of this unit, students should be able to:
6. Explore positioning, differentiation, and pricing strategies for effective marketing scenarios.
6.1 Compare the pricing strategies of a company and its competitors.
6.2 Describe pricing, distribution, or product strategies of a company with respect to the level of
differentiation.
6.3 Summarize how macro and micro environmental changes will impact a company.
Reading Assignment
Chapter 16:
Developing Pricing Strategies and Programs
Chapter 17:
Designing and Managing Integrated Marketing Channels, pp. 493–502
Chapter 18:
Managing Retailing, Wholesaling, and Logistics, pp. 527–542
Unit Lesson
Price is defined as the amount of money that is exchanged for something of value, which is defined by the
customer. This value proposition directly aligns with the amount of money that a consumer is willing to pay for
the prescribed product and/or service. Prices are adjusted based upon discounts, which could include
seasonal discounts, quantity discounts, cash discounts and/or simply sales discounts. Another factor that
could change the price are allowances; which include trade-ins and damaged goods allowances. Prices can
be set based upon a one-price policy, which suggests that prices are the same for everyone. These tend to
be low-cost, frequently purchased, and convenience goods. Alternatively, prices can be set based upon a
flexible price policy, which allows for prices to be set differently for different customers. These prices tend to
be set by salespeople who are working directly with the customer. A good salesperson understands his or her
customer enough to know how high of a price the customer will bear and will adjust the price accordingly in
order to secure the business. This model is used at car dealerships within the business-to-consumer (B2C)
model as well as in most purchasing situations in the business-to-business (B2B) sector.
As the marketing team looks to establish pricing policies, company-wide marketing objectives need to be
analyzed. The first pricing objective might be profit-oriented, which includes the concepts below.
Target return: This pricing policy establishes a predetermined profit level guideline. This could be a
return on investment or a certain sales level. Prices are then based upon this guideline.
Maximize profits: This pricing policy suggests that prices will be set as high as possible in order to
maximize profit levels. While this seems like an ideal alternative, careful research must be conducted
to understand the profit level that the customer will bear before moving on to the competitor.
UNIT VI STUDY GUIDE
Pricing and Distribution Strategies
MBA 5501, Advanced Marketing 2
Another pricing objective might be sales-oriented, which focuses on increased sales without regard to profit
levels. This alternative se ...
Similar to Chapter 13 pricing pharmacist services (20)
If you want to be a better leader, you should read more -- either fiction or non-fiction. This slide presents the lessons from one book that I read many years ago. The lessons have stuck with me.
Teaching the history of pharmacy to young people is a challenge but it can be done if delivered in an interesting and engaging way. These slides summarize what I share with my students.
Much of our ideas about motivating others are inconsistent with what science says. This presentation describes three commonly used methods to motivate. Only one is under the control of all pharmacists and pharmacy personnel.
Whenever people work together on things of importance, there will be disagreements and conflict. Understanding conflicts and how to work them out is a key responsibility of professionals and leaders. When handled well, conflicts can improve relationships, solve difficult problems, and influence change in organizations.
The following slides describe how to have trusting professional relationships. Mutual trust between partners is fundamental to commitment and engagement.
The following slides describe how pharmacists can have better professional relationships which are fundamental to pharmacy practice. Effective professional relationships are vital in leading others, teaching and coaching performance, negotiating win-win solutions, and resolving conflict in pharmacy organizations. Good professional relationships help improve communications, make work more enjoyable, and increase opportunities for success.
These slides cover the concepts of situational leadership -- a group of theories that highlight the role of context in effective leadership. The ability to read a situation and apply the right leadership style is critical for successful leadership.
Ethical leadership can be defined as the process through leaders attempt to accomplish morally defensible goals in a morally defensible manner. These slides review what it means to be an ethical leader and the process for being one.
Pharmacists can learn from the accumulated wisdom of the leadership literature to be better leaders. These slides summarize the major ideas covered in Chapter 2 of "Leadership for Pharmacists". It provides a brief review of leadership theories and what pharmacists can learn from them.
This is an updated slide deck discussing what students should consider when starting a career in community pharmacy practice. There really are a lot of opportunities if pharmacists are willing to do what it takes to succeed.
This chapter discusses the topic of motivation and the science behind it. It differentiates motivation from the concepts of morale and performance. It examines key motivation theories and what they say about what drives human behavior. The chapter identifies important lessons for pharmacists from each theory. Throughout, it describes misconceptions relating to things that motivate us and others and how misconceptions can lead to unintended behavioral consequences.
These slides accompany Chapter 7 from Leadership for Pharmacists. It lays out different types of problems faced by pharmacists and issues to consider. It identifies some cognitive biases and bad decision-making processes that can prevent good solutions. A systems approach using a step-by-step process for making good decisions is presented.
This is a basic introduction to leadership from Chapter One from Leadership for Pharmacists. It explains why pharmacists should learn about leadership by using statements from professional organizations and the pharmacy literature. Leadership and management are defined and contrasted. The role of power in leading change is discussed along with a discussion that contrasts how leaders and managers use power differently. The chapter ends by providing a short summary of what is known about leadership.
This presents the resource-based theory of competitive advantage as a framework for describing, understanding, and predicting the adoption and dissemination pharmacy service innovations into routine practice. The theory argues that sustainability of any business innovation (e.g., pharmacy service) is based upon (1) the internal resources of the firm offering it, (2) the firm’s capabilities in using those resources, (3) the competitive advantage to the firm of its resources and capabilities, (4) the attractiveness of the market in which it competes, and (5) the innovation’s contribution to financial performance of the firm.
This is a pitch deck template for pharmacy business models. It is for pharmacy projects that are in the advanced stages of planning. A previous 9 slide pitch deck without financials is available for early stage strategic planning.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
3. Learning Objectives
Explain importance of pricing
Discuss relationship to other elements of
marketing mix
Discuss influences on pricing decisions
Calculate the cost of providing a pharmacist
service
Explain the relationships among price, cost, and
demand for a pharmacist service
Describe potential steps for pricing pharmacist
services
3
4. Organization's
Operation - Specific
background about
the organization
where the
product/service will
be provided
Strengths,
Weaknesses - Your
capabilities to serve
targeted customers
Service/Product – Features and details about
your program or service
Secondary
Customers - all
other people you
may serve
Partners - People or
businesses who can
help you serve
customers
Value Proposition - The case you make to
customers
Opportunities,
Threats - Potential
for success or failure
in the market
Competitors –
Alternatives for your
value proposition
Primary Customers - People or businesses you
want to serve
Costs - Financial and nonfinancial inputs
needed to serve customers
Pricing & Reimbursement - Sources of revenue
to sustain your value proposition
Communication Plan - How value
proposition is communicated
Implementation - Details about critical factors for success of business
Source: (adapted) Osterwalder A, Pigneur Y. Business Model Generation: A Handbook for Visionaries, Game Changers, and Challengers. Hoboken, NJ.: John Wiley and Sons; 2010.
Business Model Canvas for Pharmacy Services
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9 6
5
4
8
10 11
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12
13
PROFIT FORMULA
5. 10. COSTS
What are the major costs of the service being
provided?
Startup Costs
Operating Costs
Fixed
Variable
6. 11. PRICING & REIMBURSEMENT
How does the business receive revenue for the
service being provided?
What will be the price for each unit of service
provided?
Who will pay for the service?
7. SCIENCE & ART OF PRICING
Science
Economics, consumer psychology
Art
experience, hunches
11. Types of Bargain Shoppers
Offline deal-seekers. Typically over age 55
and love to find deals in stores. Online and
digital are less important
Deal thrillers. Deal thrillers love getting a
deal but are also loyal to specific brands.
Deal takers. Highly educated and affluent
consumers who do not seek deals but will
accept one if offered.
Deal indifferents. Largest segment of the
population, and they do not respond to
deals. Most only shop when they have a
specific need, and coupons are wasted on
them.
Deal-seeker influentials. Constantly look for
the best online, offline and mobile deals.
Tend to be young, highly educated, socially
active consumers who love shopping but
think paying full price is for suckers.
Deal rejectors. Hate shopping, preferring
convenience over everything. They tend to
be male, older, and willing to pay more for
convenience.
Source: Brooks C. 6 Kinds of Deal Seekers and What They Mean to Your Business. 1-9-2014. Business News Daily.
12. CONSIDERATIONS IN PRICING
• customers/stakeholders
PERSPECTIVE
• B2C, B2B, and/or B2G
MARKET
• non-durable goods, durable goods, services
PRODUCT
• Intensity of competition, ease of market entry, availability of
substitutes
BUYER’S POWER
13. PRICING AND STRATEGY
Pricing is driven by business strategy
Low cost strategies require prices that
undercut competitors
Luxury strategies allow prices above the
competition
14. Reframing the low cost argument
Making a business case to payers (B2B) that
pharmacists add value by:
• improving medication adherence,
• coordinating care,
• promoting health, and
• reducing avoidable emergency department
visits, doctors visits, hospitalizations, and
nursing home admissions
15. PRICE AND BRANDING
A strong brand can yield a higher price.
The brand is a promise that tells buyers that
"if you buy this brand, it will be worth the
extra you pay for it."
Pharmacists can garner higher prices by
communicating a strong story about their
brand and its value.
16. Step 1.
Set price
objectives
Step 2.
Estimate
costs
Step 3.
Estimate
Demand
Step 4.
Set a Price
Step 5.
Change the
Price as
Needed
HOW TO PRICE
PHARMACIST
SERVICES
18. Step 2: Estimate Costs
Service costs, product costs, & net profit.
Startup & operating costs
Fixed & variable costs
Direct & indirect costs
19. Step 3: Estimate Demand
Determined by consumers’:
• needs/wants
• perception of the pharmacist and pharmacy
• perceptions of price and value
• availability of competing services
• ability to compare competing services
• price sensitivity (described as elasticity of demand)
• switching costs
20. Step 4: Set a Price
Price as a Signal of Quality
24. Business Case
Defined as a document or presentation that
justifies an initiative
Typically an economic value proposition
to an audience of decision makers that
makes a case that an initiative will generate
greater benefit than what the initiative costs
25. A return on investment (ROI)
calculation is usually expected by
institutional decision makers to guide
their decisions
Gain from Investment – Cost
Cost
ROI =
26. Conclusions
Pricing is an art & science
It is key to sustainable pharmacist services
Pharmacies with strong brands can set
command higher prices