The document discusses the key components and structure of an effective Letter of Inquiry (LOI). An LOI is a short preliminary proposal submitted to funding agencies. It should follow the agency's guidelines and include an abstract, introduction/background, statement of need, objectives/aims, strategy/goals, leadership/organization, budget, and impact/significance. The LOI must clearly and concisely address why the project is important, why the applicant should receive funding, why the proposed institution is suitable, why the specific agency is the appropriate sponsor, and why the project should be undertaken now.