This is a short presentation which helps to understand Cell cycle and Regulation. But it is recommended to read Lodish as reference material to understand this.
Basic Cell cycle regulation suitable for undergraduate students.
This presentation has been started from the basics to enable easy understanding. It covers all the details of cell cycle regulation in yeast as well as higher eukaryotes.
Basic Cell cycle regulation suitable for undergraduate students.
This presentation has been started from the basics to enable easy understanding. It covers all the details of cell cycle regulation in yeast as well as higher eukaryotes.
T-Cell Activation
• Concept of immune response
• T cell-mediated immune response
• B cell-mediated immune response
I. Concept of immune response
• A collective and coordinated response to the introduction of foreign substances in an individual mediated by the cells and molecules in the immune system.
II. T cell-mediated immune response
• Cell-mediated immunity is the arm of the adaptive immune response whose role is to combat infection of intracellular pathogens, such as intracellular bacteria (mycobacteria, listeria monocytogens), viruses, protozoa, etc.
GENERAL IDEA OF SIGNAL TRANSDUCTION
DEFINATION
WHAT DOES THE TERM SIGNAL TRANSDUCTION MEANS
HISTORY
BASIC ELEMENTS IN SIGNAL TRANSDUCTION
TYPES OF SIGNAL TRANSDUCTION
SIGNALLING MOLECULE
RECEPTOR MOLECULE
MODES OF CELL CELL SIGNALING
SECOND MESSENGER
SIGNAL TRANSDUCTION PATHWAY
SOME SIGNALING PATHWAYS
SIGNIFICANCE
CONCLUSION
REFERENCE
In biology, cell signaling is part of any communication process that governs basic activities of cells and coordinates multiple-cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity, as well as normal tissue homeostasis.
Structure and functions of MitochondriaICHHA PURAK
This Power Point Presentation (PPT) entitled “Structure and Functions of Mitochondria” consists of 118 slides with following sub-heads
INTRODUCTION
HISTORY
ORIGIN AND EVOLUTION OF MITOCHONDRIA
SYNTHESIS OF MITOCHONDRIA
ISOLATION OF MITOCHNDRIA
SHAPE , SIZE AND NUMBER OF MITOCHONDRIA
STRUCTURE OF MITOCHONDRIA
CHEMICAL COMPOSITION OF MITOCHONDRIA
FUNCTIONS OF MITOCHONDRIA
MITOCHONDRIA –POWER HOUSE OF CELL
MITOCHONDRIAL DNA/ GENOME
TRANSPORT OF PROTEINS INTO MITOCHONDRIA
MITOCHONDRIAL INHERITANCE
MITOCHONDRIAL DISEASES IN HUMAN
SUMMARY
QUESTIONS
BOOKS CONSULTED
REFERENCES
The presentation outlines aspects of immunity against cancer, evasion strategies by cells, immunotherapy in cancer, cancer vaccines etc. Download and view the slideshow for better experience.
Prepared in Sept 2014
The Wnt cascade has emerged as a critical regulator of stem cells. In many tissues, activation of Wnt signaling has also been found to be associated with cancer. Understanding the regulation by Wnt signaling may serve as a paradigm for understanding the dual nature of self-renewal signals.
T-Cell Activation
• Concept of immune response
• T cell-mediated immune response
• B cell-mediated immune response
I. Concept of immune response
• A collective and coordinated response to the introduction of foreign substances in an individual mediated by the cells and molecules in the immune system.
II. T cell-mediated immune response
• Cell-mediated immunity is the arm of the adaptive immune response whose role is to combat infection of intracellular pathogens, such as intracellular bacteria (mycobacteria, listeria monocytogens), viruses, protozoa, etc.
GENERAL IDEA OF SIGNAL TRANSDUCTION
DEFINATION
WHAT DOES THE TERM SIGNAL TRANSDUCTION MEANS
HISTORY
BASIC ELEMENTS IN SIGNAL TRANSDUCTION
TYPES OF SIGNAL TRANSDUCTION
SIGNALLING MOLECULE
RECEPTOR MOLECULE
MODES OF CELL CELL SIGNALING
SECOND MESSENGER
SIGNAL TRANSDUCTION PATHWAY
SOME SIGNALING PATHWAYS
SIGNIFICANCE
CONCLUSION
REFERENCE
In biology, cell signaling is part of any communication process that governs basic activities of cells and coordinates multiple-cell actions. The ability of cells to perceive and correctly respond to their microenvironment is the basis of development, tissue repair, and immunity, as well as normal tissue homeostasis.
Structure and functions of MitochondriaICHHA PURAK
This Power Point Presentation (PPT) entitled “Structure and Functions of Mitochondria” consists of 118 slides with following sub-heads
INTRODUCTION
HISTORY
ORIGIN AND EVOLUTION OF MITOCHONDRIA
SYNTHESIS OF MITOCHONDRIA
ISOLATION OF MITOCHNDRIA
SHAPE , SIZE AND NUMBER OF MITOCHONDRIA
STRUCTURE OF MITOCHONDRIA
CHEMICAL COMPOSITION OF MITOCHONDRIA
FUNCTIONS OF MITOCHONDRIA
MITOCHONDRIA –POWER HOUSE OF CELL
MITOCHONDRIAL DNA/ GENOME
TRANSPORT OF PROTEINS INTO MITOCHONDRIA
MITOCHONDRIAL INHERITANCE
MITOCHONDRIAL DISEASES IN HUMAN
SUMMARY
QUESTIONS
BOOKS CONSULTED
REFERENCES
The presentation outlines aspects of immunity against cancer, evasion strategies by cells, immunotherapy in cancer, cancer vaccines etc. Download and view the slideshow for better experience.
Prepared in Sept 2014
The Wnt cascade has emerged as a critical regulator of stem cells. In many tissues, activation of Wnt signaling has also been found to be associated with cancer. Understanding the regulation by Wnt signaling may serve as a paradigm for understanding the dual nature of self-renewal signals.
Cell cycle regulation presentation by me and my colleagues. Not the Best work but still it will give a general idea about DNA damage checkpoints, roles of Cdk-Cyclin complexes, Rb proteins, ATM&ATR kinases, p51, etc.
Reference : Nature reviews & The Cell a molecular approach. (cooper)
cell cycle
The cell cycle is the process a cell undertakes to replicate all of its genetic material and divide into two identical cells. There is different stages of the cell cycle and what happens in each stage. We will also consider the regulation of the cell cycle, and look at some examples of its dysregulation.
Cell cycle and mitosis presentation (3)Ritu Sharma
The cell cycle is an ordered set of events, culminating in cell growth and division into two daughter cell.Cell division and tissue growth is a controlled and complex process. Cancer is a disease where regulation of the cell cycle goes messy and normal cell growth and behavior is lost.
This presentation is regarding the normal cell cycle through which a cell passes throughout its life. It highlights each step in the formation of daughter cells from a mother cell. It puts light on the events in both the interphase and division (mitotic) phase and the resting (G0 phase).
You will also get knowledge about the cell cycle checkpoints and the cellular brakes, the proteins that keeps the cell to divide normally, and how the abnormalities in these proteins results in defects of cell cycle and subsequently leads to uncontrolled cell division and cancer formation.
describe cell cycle and cell cycle control system for downloading the presentation , more presentations , infographics and blogs visit :
studyscienceblog.wordpress.com
The cell cycle, or cell-division cycle, is the series of events that take place in a cell that cause it to divide into two daughter cells. These events include the duplication of its DNA (DNA replication) and some of its organelles, and subsequently the partitioning of its cytoplasm and other components into two daughter cells in a process called cell division.
here u will find every detail of cell cycle.
for more details ,visit @biOlOgy BINGE-insight learning
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Biological screening of herbal drugs: Introduction and Need for
Phyto-Pharmacological Screening, New Strategies for evaluating
Natural Products, In vitro evaluation techniques for Antioxidants, Antimicrobial and Anticancer drugs. In vivo evaluation techniques
for Anti-inflammatory, Antiulcer, Anticancer, Wound healing, Antidiabetic, Hepatoprotective, Cardio protective, Diuretics and
Antifertility, Toxicity studies as per OECD guidelines
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
Macroeconomics- Movie Location
This will be used as part of your Personal Professional Portfolio once graded.
Objective:
Prepare a presentation or a paper using research, basic comparative analysis, data organization and application of economic information. You will make an informed assessment of an economic climate outside of the United States to accomplish an entertainment industry objective.
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
Francesca Gottschalk - How can education support child empowerment.pptxEduSkills OECD
Francesca Gottschalk from the OECD’s Centre for Educational Research and Innovation presents at the Ask an Expert Webinar: How can education support child empowerment?
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
3. Introduction to Cell Cycle
The organism develops from a single cell zygote to a complete organism because of cell
division and cell growth.When cell cycles proceed inappropriately (e.g., cells divide
uncontrollably), pathological conditions like cancer can result.
There are 2 major phase: Interphase and M phase
Interphase includes:
G1 Phase: In this part of interphase, the cell grows in size and synthesizes mRNA
and proteins in preparation for subsequent steps leading to mitosis
S Phase: S-phase (synthesis phase) is the part of the cell cycle in which DNA is
replicated, occurring between G1 phase and G2 phase.
G2 Phase: After DNA replication, the cell leaves S phase and enters G2, when the cell
prepares for mitosis or meiosis.
M Phase: Mitosis or meiosis takes place in this part. The DNA is divided into two cells.
4. Mitosis v/s Meiosis
Mitosis Meiosis
Occurs in all somatic cells Occurs only in reproductive (sex) cells
Chromosome number remains same, i.e.,
diploid (2n), hence it is equational
division
Chromosome number reduces to half, i.e., haploid (n), hence it is
reductional division
Two daughter cells are produced Four daughter cells are produced
One cell division involves four phases
Consists of two sub-divisions: Meiosis - I and Meosis - II each
involving four phases. Prophase - I is again subdivided into five sub-
stages:-leptotene, zygotene, pachytene, diplotene and diakinesis
No crossing over Crossing over takes place during prophase1 of meiosis
Daughter cells have identical
chromosomes to parent cell, i.e., genetic
material remains constant
Daughter cells have chromosomes with combined genetic material
from both parents i.e., genetic variability occurs
5. Cell Regulation and checkpoints
A checkpoint is a stage in the eukaryotic cell cycle at which at which the cell
examines internal and external cues and "decides" whether or not to move forward
with division.
There are a number of checkpoints, but the three most important ones are:
G1 checkpoint at G1/S transition
G2 checkpoint at G2/M transition
In M phase, from Metaphase to Anaphase
6. First Checkpoint: The G1 checkpoint
The G1 checkpoint is the main decision point for a
cell – that is, the primary point at which it must
choose whether or not to divide. Once the cell
passes the G1checkpoint and enters S phase, it
becomes irreversibly committed to division. That is,
barring unexpected problems, such as DNA damage
or replication errors, a cell that passes the G1
checkpoint will continue the rest of the way
through the cell cycle and produce two daughter
cells.
G1 checkpoint checks for:
● Cell Size
● Nutrient
● Growth Factors
● DNA Damage
If a cell doesn’t get the go-ahead cues it
needs at the G1 checkpoint, it may leave
the cell cycle and enter a resting state
called G0. Some cells stay permanently
in G0 while others resume dividing if
conditions improve.
7.
8. Second checkpoint: The G2 Checkpoint
To make sure that cell division goes smoothly (produces healthy daughter cells with complete,
undamaged DNA), the cell has an additional checkpoint before M phase, called the G2.At this
stage, the cell will check:
DNA integrity & DNA replication.
If errors or damage are detected, the cell will pause at the G2 checkpoint to allow for repairs.
If the checkpoint mechanisms detect problems with the DNA, the cell cycle is halted, and the
cell attempts to either complete DNA replication or repair the damaged DNA.
If the damage is irreparable, the cell may undergo apoptosis, or programmed cell death This
self-destruction mechanism ensures that damaged DNA is not passed on to daughter cells and
is important in preventing cancer.
9. Third Checkpoint:The spindle checkpoint
The M checkpoint is also known as the spindle checkpoint: here, the cell examines
whether all the sister chromatids are correctly attached to the spindle microtubules.
Because the separation of the sister chromatids during anaphase is an irreversible step,
the cycle will not proceed until all the chromosomes are firmly attached to at least two
spindle fibers from opposite poles of the cell.
How does this checkpoint work?
It seems that cells don't actually scan the metaphase plate to confirm that all of the
chromosomes are there. Instead, they look for "straggler" chromosomes that are in the
wrong place (e.g., floating around in the cytoplasm) If a chromosome is misplaced, the
cell will pause mitosis, allowing time for the spindle to capture the stray chromosome
11. xx%
Use this slide to show a major stat. It can help enforce the presentation’s main
message or argument.
12. “The mers were also designed to reproduce
only at long intervals, in order to maintain
the natural balance of the environment in
which they were placed ”
- Joan D. Vinge