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The Cell
Antoni  van  Leeuwenhoek ,[object Object],[object Object],[object Object],[object Object]
Types  of  Microscopes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
Image under Compound  microscope Scanning  EM Transmission  EM
CELL ,[object Object],[object Object],[object Object],[object Object],[object Object]
Cell Diversity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
3 Main Parts ,[object Object],[object Object],[object Object]
1. Plasma Membrane ,[object Object],[object Object],[object Object],[object Object],[object Object]
Plasma Membrane ,[object Object],[object Object],[object Object],[object Object],[object Object]
Plasma Membrane ,[object Object],[object Object],[object Object]
Plasma Membrane
rane
Definition of Terms ,[object Object],[object Object],[object Object],[object Object],[object Object]
Definition of Terms ,[object Object],[object Object],[object Object]
Definition of Terms ,[object Object],[object Object],[object Object]
Substances move across cellular membranes by: ,[object Object],[object Object],[object Object],[object Object]
Passive Processes ,[object Object],[object Object],[object Object],[object Object]
Diffusion
2 Types of Diffusion ,[object Object],[object Object],[object Object]
Simple Diffusion
2 Types of Diffusion ,[object Object],[object Object],[object Object]
 
2 Types of Diffusion ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
Passive Processes 2.  OSMOSIS  = net movement of water through a selectively permeable membrane - water moves from an area of higher water to an area of lower water concentration - or, from an area of lower solute concentration to an area of higher solute concentration OSMOTIC PRESSURE – depends on the concentration of its solute particles  - the higher the solute conc., the higher the osmotic pressure
Osmosis
EFFECT  of  OSMOSIS  in  CELLS ISOTONIC   = any solution in w/c cells maintain their normal shape and volume, concentrations of solutes are same on both sides   =  tissue  fluids, blood  plasma, 0.9%  NSS, 5%  dextrose (glucose) HYPOTONIC   = lower concentration of solutes (higher conc. of H2O) than the cytosol inside the cell    = cell swells --> ruptures HYPERTONIC  = higher concentration of solutes (lower conc. of water) than the cytosol inside the cell   = cell shrinks
Effects of Osmosis
Passive Processes 3. FILTRATION  = process by w/c H2O and solutes are forced through a membrane (or capillary wall) by  fluid  or  hydrostatic pressure  (pressure gradient) e.g.  filtering capacity of the kidney (e.g. in urine formation)
Active Processes 1.  ACTIVE TRANSPORT   - cellular energy is used to transport substances across the membrane against a concentration gradient (from an area of low to an area of high concentration), needs ATP  - splitting of ATP changes the shape of a transporter protein (PUMP) --> moves a substance across the membrane against its conc. gradient - Na, K, H, Ca, I, Cl
Active Transport
Active Processes 2.  TRANSPORT IN VESICLES  - VESICLE   –  small round sac formed by budding off from an existing membrane - transport substances, take in and release substances  - requires energy (ATP)
2 Types of Transport in Vesicles 1. ENDOCYTOSIS –   materials move into a cell in a vesicle formed from the plasma membrane   - substances are surrounded by a piece of the plasma membrane w/c buds off inside the cell to form a vesicle containing the ingested substances.
[object Object],[object Object],[object Object],2 Types of Endocytosis
[object Object],[object Object],2 Types of Endocytosis
2 Types of Transport in Vesicles 2. EXOCYTOSIS   – results in secretion (release of materials from a cell) a. SECRETORY CELLS – release digestive enzymes, hormones,  mucus, etc. b. NERVE CELLS – during release of neurotransmitters  * membrane-enclosed secretory vesicles form inside the cell, fuse w/ the cell membrane, and release contents into the ECF
Exocytosis
Table. 3.2
Specializations of the Plasma Membrane ,[object Object],[object Object]
Membrane Junctions ,[object Object],[object Object],[object Object],[object Object]
2. Cytoplasm ,[object Object],[object Object],[object Object],[object Object]
1. Cytoskeleton ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
1. Cytoskeleton 2. INTERMEDIATE FILAMENTS   – found in parts of cells subject to tension (stretching), hold organelles in place, intercellular attachment  3. MICROTUBULES   – long, hollow tubes, determines cell shape, movement of organelles w/in the cell, migration of chromosomes during cell division, movement of cilia and flagella
 
[object Object],[object Object],[object Object],[object Object],2 . Centrosome
3. Cilia and Flagella ,[object Object],[object Object],[object Object]
4. Ribosomes ,[object Object],[object Object],[object Object],[object Object],[object Object]
5. Endoplasmic Reticulum (ER) ,[object Object],[object Object],[object Object],[object Object]
5. Endoplasmic Reticulum (ER)
6. Golgi Complex ,[object Object],[object Object],[object Object],[object Object],[object Object]
 
7. Lysosomes ,[object Object],[object Object],[object Object]
 
8. Peroxisomes ,[object Object],[object Object],[object Object],[object Object],[object Object]
9. Proteasomes ,[object Object],[object Object]
10. Mitochondria ,[object Object],[object Object]
3. Nucleus ,[object Object],[object Object],[object Object],[object Object]
3. Nucleus ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
 
 
Protein Synthesis ,[object Object],[object Object],[object Object]
Transcription ,[object Object],[object Object],[object Object],[object Object]
3 Kinds of RNA ,[object Object],[object Object],[object Object]
Base pairing
Translation ,[object Object],[object Object],[object Object],[object Object]
 
Somatic Cell Division ,[object Object],[object Object]
2 Types of Cell Division ,[object Object],[object Object],[object Object],[object Object]
Prerequisite of somatic cell division: DNA Replication  ,[object Object],[object Object],[object Object],[object Object]
[object Object],Prerequisite of somatic cell division: DNA Replication
DNA Replication
Cell Cycle ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],Interphase
Mitotic Phase ,[object Object],[object Object],[object Object]
[object Object],[object Object],Mitosis
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Cytokinesis ,[object Object],[object Object],[object Object]
 
END ,[object Object]

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Cell

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  • 6. Image under Compound microscope Scanning EM Transmission EM
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  • 27. Passive Processes 2. OSMOSIS = net movement of water through a selectively permeable membrane - water moves from an area of higher water to an area of lower water concentration - or, from an area of lower solute concentration to an area of higher solute concentration OSMOTIC PRESSURE – depends on the concentration of its solute particles - the higher the solute conc., the higher the osmotic pressure
  • 29. EFFECT of OSMOSIS in CELLS ISOTONIC = any solution in w/c cells maintain their normal shape and volume, concentrations of solutes are same on both sides = tissue fluids, blood plasma, 0.9% NSS, 5% dextrose (glucose) HYPOTONIC = lower concentration of solutes (higher conc. of H2O) than the cytosol inside the cell = cell swells --> ruptures HYPERTONIC = higher concentration of solutes (lower conc. of water) than the cytosol inside the cell = cell shrinks
  • 31. Passive Processes 3. FILTRATION = process by w/c H2O and solutes are forced through a membrane (or capillary wall) by fluid or hydrostatic pressure (pressure gradient) e.g. filtering capacity of the kidney (e.g. in urine formation)
  • 32. Active Processes 1. ACTIVE TRANSPORT - cellular energy is used to transport substances across the membrane against a concentration gradient (from an area of low to an area of high concentration), needs ATP - splitting of ATP changes the shape of a transporter protein (PUMP) --> moves a substance across the membrane against its conc. gradient - Na, K, H, Ca, I, Cl
  • 34. Active Processes 2. TRANSPORT IN VESICLES - VESICLE – small round sac formed by budding off from an existing membrane - transport substances, take in and release substances - requires energy (ATP)
  • 35. 2 Types of Transport in Vesicles 1. ENDOCYTOSIS – materials move into a cell in a vesicle formed from the plasma membrane - substances are surrounded by a piece of the plasma membrane w/c buds off inside the cell to form a vesicle containing the ingested substances.
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  • 38. 2 Types of Transport in Vesicles 2. EXOCYTOSIS – results in secretion (release of materials from a cell) a. SECRETORY CELLS – release digestive enzymes, hormones, mucus, etc. b. NERVE CELLS – during release of neurotransmitters * membrane-enclosed secretory vesicles form inside the cell, fuse w/ the cell membrane, and release contents into the ECF
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  • 45. 1. Cytoskeleton 2. INTERMEDIATE FILAMENTS – found in parts of cells subject to tension (stretching), hold organelles in place, intercellular attachment 3. MICROTUBULES – long, hollow tubes, determines cell shape, movement of organelles w/in the cell, migration of chromosomes during cell division, movement of cilia and flagella
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