2. A previously healthy 4-year-old girl presented
with a 2-day history of severe nausea,
vomiting, and diarrhea. Her symptoms
began with severe pain in the mid to upper
abdomen by alternating episodes of vomiting
and nonbloody diarrhea. Laboratory
diagnosis show urease positive. Gram stain
and culture show curved gram-negative rod
3. severe nausea
vomiting
diarrhea (nonbloody diarrhea )
abdominal pain
severe pain mid to upper abdomen
6. TheVac A
cytotoxin
produce protein
cause vacuole.
Vacuole
cause pore
formation in
human cells
cagA gene
product injected
in host cell
Changes in host cell
signaling
7. Endoscopy
Urease test of biopsy relatively sensitive and
highly specific .
Urea breath test.
ELISA
FecalAntigenTest
