This document presents a case study of a 21-year-old male patient admitted to the hospital with duodenal ulcer. Objective findings from examinations confirmed the diagnosis of duodenal ulcer seen on endoscopy. The patient's history of irregular eating habits and skipping meals contributed to ulcer development. A treatment plan was developed using pantoprazole, sucralfate, tramadol, ondansetron, and magnesium hydroxide to treat the ulcer and relieve symptoms while monitoring for drug toxicity and therapeutic response through follow-up endoscopy. Patient education focused on the disease, medication use, and importance of regular eating.
A 50 year old female patient was admitted to the female medicine ward with complaints of constipation (today), breathlessness, coughing, b/l pedal oedema, anasarca since 7 days.
A 50 year old female patient was admitted to the female medicine ward with complaints of constipation (today), breathlessness, coughing, b/l pedal oedema, anasarca since 7 days.
The Subjective, Objective, Assessment and Plan (SOAP).the assessment will identify what the drug related/induced problem is likely to be and the reasoning/evidence behind it. This will include etiology and risk factors, assessments of the need for therapy, current therapy, and therapy options.
CASE PRESENTATION OF JAUNDICE INCLUDES PATIENT DEMOGRAPHICS, PAST MEDICAL AND MEDICATION HISTORY, FAMILY HISTORY, SURGICAL HISTORY, PERSONAL HISTORY, ON EXAMINATION, LABORATORY INVESTIGATIONS, DIAGNOSIS, SOAP NOTES, TREATMENT, DISEASE INFORMATION, PATIENT COUNSELLING, LIFE STYLE MODIFICATIONS.
A 25 year old female patient was admitted to the female medicine ward with complaints of fever with chills since 1 and 1/2 months, bod ache, cough with expectoration since 10-15 days, weakness with giddiness.
a case presentation on diabetic foot/ case study on diabetic foot.martinshaji
This is a detailed study on diabetic foot a condition usually seen on patients with diabetics. this may become complicated according to the severity of the condition and diabetes , ideal management is needed with drugs sometimes surgical methods. this case study will give a detailed study about diabetic foot ............... the treatment, diagnosis , management, patient counselling, pharmacist intervention, pathophysiology etc
Please leave a comment if you visited this
thank u
The Subjective, Objective, Assessment and Plan (SOAP).the assessment will identify what the drug related/induced problem is likely to be and the reasoning/evidence behind it. This will include etiology and risk factors, assessments of the need for therapy, current therapy, and therapy options.
CASE PRESENTATION OF JAUNDICE INCLUDES PATIENT DEMOGRAPHICS, PAST MEDICAL AND MEDICATION HISTORY, FAMILY HISTORY, SURGICAL HISTORY, PERSONAL HISTORY, ON EXAMINATION, LABORATORY INVESTIGATIONS, DIAGNOSIS, SOAP NOTES, TREATMENT, DISEASE INFORMATION, PATIENT COUNSELLING, LIFE STYLE MODIFICATIONS.
A 25 year old female patient was admitted to the female medicine ward with complaints of fever with chills since 1 and 1/2 months, bod ache, cough with expectoration since 10-15 days, weakness with giddiness.
a case presentation on diabetic foot/ case study on diabetic foot.martinshaji
This is a detailed study on diabetic foot a condition usually seen on patients with diabetics. this may become complicated according to the severity of the condition and diabetes , ideal management is needed with drugs sometimes surgical methods. this case study will give a detailed study about diabetic foot ............... the treatment, diagnosis , management, patient counselling, pharmacist intervention, pathophysiology etc
Please leave a comment if you visited this
thank u
Pancreatitis is the Inflammation of the pancreatic parenchyma. Acute condition of diffuse pancreatic inflammation & auto digestion, presents with abdominal pain, and is usually associated with raised pancreatic enzyme levels in the blood &urine. this is a case study on acute pancreatitis describing factors such as patient demographic data , pharmacist intervention , pathophysiology , treatment , prevention , imaging techniques , diagnosis , lab investigation etc
this case study was prepared for my academic purpose ......
please comment .........
thank u,,,,,
GERD ( Gasrtro-esophageal reflux disease )
Gastroesophageal reflux disease (GERD) is a condition in which the stomach contents (food or liquid) leak backwards from the stomach into the esophagus (the tube from the mouth to the stomach). This action can irritate the esophagus, causing heartburn and other symptoms.
And Case study at the end
Ondansetron Oral Solution IP 2mg-5ml Manufacturers, Suppliers in India.pdfTajPharmaIndia
Ondansetron is used to treat nausea and vomiting caused by chemotherapy. It is also used to prevent or treat nausea and vomiting after surgery.
Ondansetron should be considered for infants and children age six months and older who present to the ED with vomiting related to suspected acute gastroenteritis, and who have mild to moderate dehydration or who have failed oral rehydration therapy.
Breast Cancer Awareness Month has
been celebrated every October for the
last 90 years. It is called as “Pink
October” as people around the world
adopt the color pink and display a pink
ribbon to raise awareness about the
importance of prevention and routine
screening for the early diagnosis of
breast cancer.The theme for Breast Cancer
Awareness Month, 2023 is 'Keeping
Her in the Picture'
, a plea to everyone
to keep an eye on the well-being of the
significant women in their lives.
Nipah virus (NiV) causes the deadly viral zoonotic infectious disease called Nipah, that can transmit from animals to humans.
Animals such as bats, most commonly the fruit bats called as flying fox and pigs were the acting carriers of Niv.
Nipah viral infection in humans results in range of clinical presentations such as asymptomatic infection (subclinical) to acute respiratory infection and fatal encephalitis.
This infection has about 40 to 75% fatality rate, which can be varied depending on the local capabilities for epidemiological surveillance and clinical management.
Presently approved treatment or vaccination is unavailable for infected rather than supportive care.
Therefore, the disease calls out for an urgent need for an approved treatment regimen for a proper cure of the disease. As stated by the 2018 annual review of the WHO R&D Blueprint list of priority diseases.
Bloating is a condition where your belly feels full and tight, often due to gas.
People might confuse bloating with other reasons for a more noticeable belly, such as abdominal wall laxity, or looseness. This is common, especially among older women and those who have had children.
It's important to know the difference so you can get the right treatment. A toned abdomen can make it easier to see a difference when the gut is full of food or stool.
Coronavirus disease 2019 (COVID-19) pandemic has a catastrophic impact on human
health.1 They cause the severe acute respiratory syndrome, leading to a significant
increase in morbidity and mortality worldwide.2 In addition to ample vaccine
availability for mitigating COVID-19, there is an urgency for an effective, easily
compatible antiviral drug. Although antivirals like Ramdesivir and Favipiravir was
tried in the early pandemic, yet it failed to exhibit the expected potency.2,3
Basics of Molnupiravir:
It is an isopropyl ester prodrug initially developed by Emory inventory. Later the
same was acquired by Merck and Ridgeback partnership.4 So far, the antivirals
terminated the elongation of RNA-chain by targeting the viral polymerase, which was
not a promising treatment of SARS-CoV-2 infections. They also had a limitation in
their administration. Whereas molnupiravir, the so-called magic pill, is an exceptional
drug with a unique error catastrophic mechanism that advances in increasing the rate
of mutation in the viral genome, outweighing the
As per a study (Sizar et al., 2021), Vitamin D deficiency (VDD) is highly prevalent among
more than one billion people worldwide. Vitamin D is of 2 types vitamin D3 and vitamin D2;
It is a prohormone and has a significant role in controlling calcium and phosphorus
metabolism. It also has anti-inflammatory, antioxidant, and anti-proliferative functions in
various parts of our body. VDD is a common symptom in most chronic and severe diseases
such as cancer (prostate, breast, and colon cancer), mental disorders, asthma, diabetic
retinopathy, infectious, autoimmune, and cardiovascular diseases. In children, VDD is linked
to detrimental defects such as rickets, dental caries, growth failure, and premature death.
VDD increases the risk of preeclampsia in pregnant women, which results in the need for a
cesarean section. Pregnant, lactating, dark-toned (highly melanin pigmented), obese
children and children and adults who abstained from direct sun exposure are at high risk of
VDD. Consequentially use of sunscreen, season, altitude, latitude, time of the day, and
clothing influence the sun-induced synthesis of vitamin D3 in the skin. UV-B and some UV-A
radiation are absorbed by sunscreen, thus preventing it from reaching the skin and leading
to VDD.
Monkeypox is derived from the genus Orthopoxvirus from the family Poxividae. This
genus has two kinds of viruses: smallpox and monkeypox virus. Monkeypox is a
zoonotic disease (spread from animal to human or vice versa) and was initially
diagnosed with pox-like symptoms on colonies of monkeys kept for research in 1958,
hence the name monkeypox. At the time of the elimination of smallpox in 1970,
monkeypox in humans was first identified in the Democratic Republic of Congo and
later in Central and Western African countries.1,2 In 2019, a newer vaccinia vaccine
was approved to prevent the disease. Furthermore, investigations are still carried out
on the same.
Animal-to-human (zoonotic) transmission can occur from direct contact with
infected animals' blood, bodily fluids, or cutaneous or mucosal lesions. In Africa,
evidence of monkeypox virus infection has been found in many animals, including
rope squirrels, tree squirrels, Gambian pouched rats, dormice, different species of
monkeys, and others. It was also found that eating improperly/half-cooked meat is
also a cause. The disease spread outside Africa by infected travellers and imported
infected animals. In 2018-2019, cases of monkeypox were confirmed in travellers
from Nigeria, Singapore, the United Kingdom, and Israel. Human-to-human
transmission can result from close contact with respiratory secretions and lesions of
the skin.3
Risk groups include people with severe illnesses who require hospitalization or an
immune-compromised person (HIV, leukaemia, etc); patients with comorbidities, a
pediatric population less than eight years old, and pregnant or breastfeeding women.2
The incubation period is generally 6-13 days, but it can range from 5-21 days. The
disease progression has two phases: The invasive phase (0-5 days), characterized by
headache, fever, back pain, myalgia, fatigue and lymphadenopathy. The rash
appearing phase (1-3 days) begins after the onset of the first phase and is
characterized by the appearance of rashes on the face and then spreads up to the
trunk and limbs of the body. Rashes evolve from macules (flat base lesions) to papules
(firm lesions), then vesicles (clear fluid- filled lesions), and finally postulates
(yellowish fluid-filled lesions) and crusts. It affects the face (in 95% of cases), palms
of the hands, and soles of the feet (in 75% of cases). Also affected were oral mucous
membranes (in 70% of cases), genitalia (30%), conjunctivae (20%), as well as cornea.
Complications of monkeypox include pneumonitis, encephalitis, sight-threatening
keratitis, and secondary bacterial infections.3,4
Nipah virus (NiV) causes the deadly viral zoonotic infectious disease called Nipah, that
can transmit from animals to humans.
• Animals such as bats, most commonly the fruit bats called as flying fox and pigs were
the acting carriers of Niv.
• Nipah viral infection in humans results in range of clinical presentations such as
asymptomatic infection (subclinical) to acute respiratory infection and fatal
encephalitis.
• This infection has about 40 to 75% fatality rate, which can be varied depending on
the local capabilities for epidemiological surveillance and clinical management.
• Presently approved treatment or vaccination is unavailable for infected rather than
supportive care.
• Therefore, the disease calls out for an urgent need for an approved treatment
regimen for a proper cure of the disease. As stated by the 2018 annual review of the
WHO R&D Blueprint list of priority diseases.
“Pharmacy strengthening health
systems” is the theme of World
Pharmacists Day on 25 September
This subject basically emphasises how crucial pharmacy is to maintaining and
strengthening the healthcare system for the benefit of people and communities
across the globe.
History of World Pharmacist Day
At the 2009 International Pharmaceutical Federation (FIP) Congress in
Istanbul, Turkey, the notion of a global pharmacist day was created. The FIP
Council selected pharmacy leaders from across the world and endorsed World
Pharmacists Day on September 25.
The Week is an initiative of the Global Alliance to Eliminate Lead Paint (Lead Paint
Alliance), which is jointly led by the UN Environment Programme (UNEP) and World
Health Organization (WHO). It takes place annually in October. International Lead
Poisoning Prevention Week 2023 takes place from 22-28 October.
The week of action aims to draw attention to the health impacts of lead exposure,
highlight efforts by countries and partners to prevent childhood lead exposure, and
accelerate efforts to phase out the use of lead in paint and paint products in future.
#leadpoisoning
Air pollution is a familiar environmental health hazard. We know what we’re looking at
when brown haze settles over a city, exhaust billows across a busy highway, or a plume
rises from a smokestack. Some air pollution is not seen, but its pungent smell alerts you.
It is a major threat to global health and prosperity. Air pollution, in all forms, is responsible
for more than 6.5 million deaths each year globally, a number that has increased over the
past two decades.
Air pollution is a mix of hazardous substances from both human-made and natural sources.
Vehicle emissions, fuel oils and natural gas to heat homes, by-products of manufacturing
and power generation, particularly coal-fueled power plants, and fumes from chemical
production are the primary sources of human-made air pollution.
Nature releases hazardous substances into the air, such as smoke from wildfires, which are
often caused by people; ash and gases from volcanic eruptions; and gases, like methane,
which are emitted from decomposing organic matter in soils.
Bloating is a condition where your belly feels full and tight, often due to gas.
People might confuse bloating with other reasons for a more noticeable belly, such as abdominal wall laxity, or looseness. This is common, especially among older women and those who have had children.
It's important to know the difference so you can get the right treatment. A toned abdomen can make it easier to see a difference when the gut is full of food or stool.
Breast Cancer Awareness Month has
been celebrated every October for the
last 90 years. It is called as “Pink
October” as people around the world
adopt the color pink and display a pink
ribbon to raise awareness about the
importance of prevention and routine
screening for the early diagnosis of
breast cancer.
The theme for Breast Cancer
Awareness Month, 2023 is 'Keeping
Her in the Picture'
, a plea to everyone
to keep an eye on the well-being of the
significant women in their lives.
Nipah virus (Niv) is a zoonotic virus that can spread between animals and people. Fruit bats, also called flying foxes, are the NIV reservoir among animals in nature. Spread of disease occurs from the infected fruit bats to other animals, such as pigs, and from infected animals to humans. The infection occurs through contaminated fruits by the animal's body fluids such as saliva, urine, or blood. Therefore, the initial spread is from animals to humans and then within humans.
Thus, the infection caused by Niv results in milder to severe illness ranging from acute respiratory tract infection to severe brain encephalitis (swelling of the brain). The Nipah outbreaks were most commonly observed in parts of Asia, primarily India and Bangladesh. This outbreak reported 40-75% of deaths in 1998 and 2018.
Past outbreaks
Nipah virus (NiV) was first identified in Malaysia and Singapore following an outbreak of disease in pigs and people in 1999. This outbreak resulted in more than 100 deaths and nearly 300 infected cases in people. More than a million pigs were killed to control further outbreaks of disease, and there have been no outbreaks in both countries since 1999.
In 2001, an annual outbreak of the disease was observed in Bangladesh. It was also periodically identified in India. The quick spread of the virus from animals to humans raised concern about NIV and made it a global pandemic.
Transmission
The first known outbreak in Singapore and Malaysia was through direct contact with the Nipah (Niv) infected pigs or their body fluids. It identified that the infected pigs got the Niv strain from bats, which subsequently resulted in transmission of the viral strains from pigs to humans by their unprotected exposure to infected animal species, which in turn led to a severe health issue in contact with humans that was even fatal due to unavailability of proper medications or vaccinations. There was no report of person-person transmission of disease in the outbreak.
Whereas person-person transmission was first reported in India (2001) and Bangladesh (2001-2008) by consumption of fruits and vegetables contaminated by the body fluids of infected animals caused Nipah virus infection.
The spread of the Nipah virus (NiV) from people was through the following causes:
• Direct contact with infected animals or their body fluids (such as bats or pigs).
• Consumption of fruits or vegetables contaminated by the body fluids of infected animals (such as palm sap).
• Close or direct contact with Niv infected person infected their body fluids (such as nasal droplets, blood, or urine).
Signs and Symptoms
The symptoms commonly appear 4-14 days after exposure to the virus. However, in many cases incubation period as long as 45 days has been reported.
Symptoms may initially include one or several of the following for 3-14days:
• Fever
• Headache
• Vomiting
Signs of respiratory illness:
• Sore throat
• Cough
• Difficulty breathing
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
3. I. PATIENT DEMOGRAPHIC DETAILS:
Hosp. No: 19046630
Name: S.S
Age: 21yrs
Gender: Male
Height: 189cm
Weight: 85kg
Date of admission: 12/1/2021
Date of discharge: 18/1/2021
3
4. II. SUBJECTIVE EVIDENCE:
Chief complaints:
• Pain in abdomen for 15 days
• Episodes of haemtemesis for 1 day
• Giddiness with Cough
5. III. OBJECTIVE EVIDENCES:
Medical history: NAD
Medication history: NAD
Social history: Mixed diet; appetite – irregular; adequate sleep
Family history: NIL
Personal history: Person was skipping meals for college
Previous allergies: Not known allergies
6. Physical examination:
GENERAL -- Conscious; well oriented; moderately built; NO PICCLE
VITAL SIGNS -- PR:86BPM; BP:110/70mmhg; SPO2: 2.99%
Systemic examinations:
RS -- NVBS blind; no added sound
GIT -- NORMAL shape; umbilicus central and inverted; all quadrants move equally with
respiration; no local rise in temp; tenderness in umbilical region resonant note heard in all region
PROVISIONAL DIAGNOSIS: Haematemesis
7. Routine biochemical examinations:
T Bilirubin: 1.78mg/dl ( 0.2 - 1.2mg/dl)
D Bilirubin: 0.44mg/dl ( 0.0 - 0.4mg/dl)
Prothrombin time: 15.5s ( 11 – 13.5s )
Others:
Endoscopy: shown ulcerated lesions above the duodenal region and confirmed as duodenal ulcer
Duodenal ulcer seen at endoscopy
8. IV. ASSESSMENT:
Final diagnosis: Based on subjective and objective evidences, patient is found to
be having DUODENAL ULCER
10. Is therapy indicated ?
Yes therapy is clearly indicated because
Clear proof of complication is obtained by diagnostic method- DUODENAL ULCER
For treating the complications
Relieving the symptoms such as abdominal pain, haemtemesis and giddiness.
11. Current therapy:
SL.NO GENERIC NAME BRAND NAME DOSE ROUTE FREQUENCY DURATION
1. RINGER LACTATE RL 100ml IV AN HOUR D1
2. PANTAPRAZOLE Inj. PANTOP 40mg IV 1-0-1 D1 - D6
3. ONDANSETRON Inj. EMESET 4mg IV S O S D1 - D6
4. TRAMADOL Inj. TRAMAZAC 50mg IV S O S D1 – D6
5. SUCRALFATE Syp. SUCRAL 30ml ORAL 1-1-1-1 D1 - D6
6. PANTAPRAZOLE Tab. PANTOP 40mg ORAL 1-0-0 D1 – D6
7. MAGNESIUM
HYDROXIDE
Syp. CREMAFFIN 10ml ORAL HS D1 – D6
13. 1. Inj. RL (100ml/hour) D1
Generic name : Ringers lactate (combination of Nacl, Na lactate, K chloride, Ca chloride)
Class : TPN (total parenteral nutrition)
MOA : For resuscitation from blood loss, produces metabolic alkalinizing effect.
Indication : Fluid and electrolyte balance
ADR : Fever, infection at site of injection, hyperkalemia
Justification : According to INTERNATIONAL JOURNAL OF CONTEMPORARY MEDICAL
RESEARCH 2017, RL is found to be superior to NS for fluid resuscitation because NS has vasodilator effect with
an increase in serum potassium level and risk of metabolic acidosis.
Since the patient is not diagnosed with hyperkalemia and hypocalcaemia RL is safe to use.
It has severe -contraindication with ceftriaxone, nitroglycerin, propanol etc. Hence not with any drugs
prescribed here
There is not any known case of hypersensitivity, which makes safe use of ringers lactate
14. 2. Inj. Pantop (40mg)(1-0-1) D1 – D6
Generic name : Pantoprazole
Class : Proton pump inhibitor
Dose : loading dose of 80mg, followed by 40mg/day. Max dose of 240mg/day in divided dose
MOA : Suppresses gastric acid secretion by inhibiting the parietal cell H+/K+ ATP pump
Indication : To treat and prevent duodenal ulcer complications. Prevent persistent cough.
ADR : Headache, diarrhea
Justification : According to AMERICAN JOURNAL OF GASTROENTEROGY,2020; Pantoprazole is
more effective than ranitidine in the treatment of duodenal ulcer providing faster healing with rare adverse effects.
According to AMERICAN JOURNAL OF HEALTH - SYSTEM PHARMACY,2021; Pantoprazole is well
absorbed, undergoes little first – pass metabolism, and has an absolute bioavailability of approx. 77%. It has
undergone 100 clinical trials with 11,000 patients for proving the effectiveness in treatment of duodenal and
gastric ulcers
15. 3. Inj. Emeset (4mg)(SOS) D1-D6
Generic name : Ondansetron
Class : Antiemetic
Dose : 4 – 8mg every 8 hours, Maximum of 16mg per dose
MOA : Works by blocking the release of the chemical serotonin in the gut and the CNS. This keeps
serotonin from causing nausea and vomiting
Indication : Prevention of nausea and vomiting
ADR : Headache(within min of administration), hypersensitivity reactions (urticaria, angioedema)
Justification : It appears in the WHO’s list of essential medicines, which is the list of medications that are
most effective and safe in meeting the important needs of health system.
It is 1 of 4 FDA approved serotonin receptor antagonists used to combat nausea and vomiting, they act both
centrally and peripherally to prevent nausea and vomiting.
According to this standard 4mg iv and 8mg oral every 12 hours, 16mg not recommended by the FDA.
16. 4. Inj. Tramazac (50mg) (SOS) D1-D6
Generic name : Tramadol
Class : Analgesic
Dose : 50mg/ml or 100mg/ml 4-6 hourly, up to total daily dose limit – 400mg
MOA : Binds to opiate receptors in the CNS causing inhibition of ascending pain pathways
Indication : Treatment of moderate to severe pain
ADR : Dizziness(14.9%), nausea(24.1%), dry mouth, drowsiness, headache, sedated state
Justification : According to FDA Drug Safety Communication, 2017; the drug is relatively safe for children ages
above 17 with right dose and frequency.
Tramadol is used worldwide and is listed in Guidelines for treatment of pain
Advisory Council on Misuse of drugs (ACMD),2017; recommended tramadol is controlled as class C substance
According to FDA can be used for moderate and moderately - severe pain in adults, max dose of 400mg and start with
25mg and daily dose of 50mg for 3 days.
17. 5. Syp. Sucral (30ml) (1-1-1-1) D1-D6
Generic name : Sucralfate
Class : Gastrointestinal agent, protectants
Dose : 30 TO 80mg/kg/day divided every 6 hour, Max dose- 1000mg/dose
MOA : It sticks to damaged ulcer tissue and protects against acid and enzymes healing can occur,
It absorb bile acid
Indication : Treatment of active duodenal ulcer
ADR : Constipation, hives, rashes, itching, dyspnea
Justification : Sucralfate is FDA approved for short – term (8weeks) treatment of duodenal ulcers.
According to NATONAL LIBRARY OF MEDICINE it is a unique anti-ulcer drug with favorable safety and
efficacy
Has less side effect compared to any drug of this category, because it is not much absorbed (3-5%), more than 90% is
excreted unchanged in faecus
18. 6. Tab. Pantop (40mg) (1-0-0) D1-D6
Generic name : Pantoprazole. tab
Class : Proton pump inhibitor
Dose : loading dose of 80mg, followed by 40mg/day. Max dose of 240mg/day in divided dose
Has to be taken 30min prior to food, don’t crush or chew the tab-just swallow
MOA : Suppresses gastric acid secretion by inhibiting the parietal cell H+/K+ ATP pump
Indication : To treat and prevent duodenal ulcer complications. Prevent persistent cough.
ADR : Allergic reactions, headache, diarrhea
Justification : According to AMERICAN JOURNAL OF GASTROENTEROGY,2020; Pantoprazole
is more effective than ranitidine in the treatment of duodenal ulcer providing faster healing with rare adverse
effects.
It is the first FDA approved PPI available both has oral and iv formulation, for short term treatment up to
16 weeks
19. 7. Syp Cremaffin (10ml) (HS) D1-D6
Generic name : Magnesium hydroxide
Class : Antacid; laxative
Dose : 800mg/5ml: 15 to 30ml/day once at bed time, Max dose of 60ml in 24 hours
MOA : Promotes bowel evacuation by causing osmotic retention of fluid which distends the colon
with increased peristaltic activity, reacts with HCl to form Mgcl
Indication : ANTACID: For temporary relief of heartburn, upset stomach
LAXATIVE: Relief of constipation
ADR : Loose, watery or more frequent stools, headache, nausea
Justification : It is an FDA approved drug for treatment with dose of 20mg for 4 weeks in adult patient of
18yrs and older.
It is an FDA approved antacid for treatment of acidity and laxative action with dose of 2-4 tsp with 8 ounce
of liquid, 4 times daily and not more than 12 tsp in 24 hrs and not max dose for more than 2 weeks
21. TREATMENT RELATED GOALS:
Overall goal is to reduce morbidity and mortality
Prevention of recurrence and progression of complication such as abdominal pain and hematemesis
To improve the quality of life
PATIENT RELATED GOALS
To treat duodenal ulcer
To restore normal GIT function
To prevent hematemesis
To reduce abdominal pain
To restore health
GOALS OF THERAPY
22. MONITORING PARAMETERES
Therapeutic monitoring:
Endoscopy for wound healing
Stool analysis for pylori infection
ECG only if there is any associated symptoms of palpitation or seizures- onansetron
PT and INR monitoring- Tramadol increase
Toxicity monitoring:
Magnesium and potassium toxicity - Ondansetron
Drug withdrawal symptom for tramadol
Hypersensitivity reactions of magnesium hydroxide
23. POINTS TO PHYSICIAN
Appetite enhancers can be given to regulate proper food habits of the patient such as Oxandrolone or
megaestrol acetate, the drugs that FDA have approved as appetite stimulants
PATIENT DUCATION
About the disease
You are suffering from duodenal ulcer which is formation of sores in the lining of intestinal duodenum- first
part of intestine, this is because of your habit of skipping meals, the gastric juice attack its own tissues forming
sores. Since it is found without much complications it was managed, further delay in treatment could bring
severe complications.
About medication
• Ringer lactate- for correcting physiological disorder-blood loss
• Pantoprazole – suppress gastric acid secretion
• Ondansetron – for vomiting and nausea- take only if needed
24. Tramadol – pain killer for abdominal pain
Sucralfate – protectant for the sore from further attack and healing
To be taken 30 min prior to antacid
Magnesium hydroxide – for easy movement of stool
This drug has to be taken 2 hour before or after taking any other medication
If you miss your dose, take it soon as possible if the duration of next drug is at least 4 hours apart
If it is near to next dose, skip the dose and continue the next dose at usual time, do not overdose.
Consult your physician for any severe side effects
Inform your doctor when any new otc drug, herbal or any vitamin supplement is taken
DISCHARGE MEDICATION
Drug Dose Frequency Duration
Syp. Sucral 30ml 1-1-1 14 days
Tab. Pantoprazole 10mg 1-0-0 14 days
Syp. Cremaffin 10ml HF 14 days
25. LIFESTYLE MODIFICATION
NEVER EVER SKIP YOUR MEAL WITHOUT ANY VALID REASON
Maintain healthy lifestyle
Eat diet rich in fiber, especially fruits such as apple, banana and vegetables such as carrot, green piece,
cabbage, beetroot and cauliflower
Take fermented foods such as yogurt
Anti- oxidant drink such as green tea is best
Leafy greens and sprouts – increased intake
Use plant based oil such as olive oil
Limit intake of caffeine, chocolates, fatty foods and spicy foods
Avoid intake of acidic foods such as citrus fruits- oranges and tomatoes
Avoid over-eating before bed
Honey, garlic, turmeric, ginger and whole grain have good ulcer protective activity
Formulated food- probiotics such as cheese, pickles and bread