The cardiovascular system includes the heart and blood vessels. The heart pumps blood into vessels that circulate it throughout the body to supply nutrients and oxygen and remove waste. The heart has four chambers - the right and left atria receive blood, and the right and left ventricles pump it out. Valves ensure blood flows in only one direction. The conduction system initiates and coordinates heart contractions. Cardiovascular disorders disrupt blood flow and heart function, while vessel disorders involve blockages or damage.
Location and orientation with the thorax
Structure of the heart
Structure of the Heart Wall
Chambers of the Heart
Valves of the Heart
Pathway of blood through the heart
Cardiac Muscle Tissue
Conducting System and Innervation
Four Steps of Cardiac Conduction
Blood Supply to the Heart
Location and orientation with the thorax
Structure of the heart
Structure of the Heart Wall
Chambers of the Heart
Valves of the Heart
Pathway of blood through the heart
Cardiac Muscle Tissue
Conducting System and Innervation
Four Steps of Cardiac Conduction
Blood Supply to the Heart
The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.
This presentation will help you to get to known about the human heart in very much clear way. It will help you alot in making your concepts clear regarding the human heart and it's functioning.
The circulatory system, also called the cardiovascular system or the vascular system, is an organ system that permits blood to circulate and transport nutrients (such as amino acids and electrolytes), oxygen, carbon dioxide, hormones, and blood cells to and from the cells in the body to provide nourishment and help in fighting diseases, stabilize temperature and pH, and maintain homeostasis.
This presentation will help you to get to known about the human heart in very much clear way. It will help you alot in making your concepts clear regarding the human heart and it's functioning.
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
1. CARDIOVASCULAR SYSTEM
Cardiovascular system includes heart and blood vessels. Heart pumps blood into the blood
vessels. Blood vessels circulate the blood throughout the body. Blood transports nutrients and
oxygen to the tissues and removes carbon dioxide and waste products from the tissues.
HEART
Heart is a muscular organ that pumps blood throughout the circulatory system. It is
situated in between two lungs in the mediastinum.
Right side of the heart has two chambers, right atrium and right ventricle. Right atrium is a
thin walled and low pressure chamber.
Right atrium receives venous (deoxygenated) blood via two large veins:
1. Superior vena cava that returns venous blood from the head, neck and upper limbs
2. Inferior vena cava that returns venous blood from lower parts of the body
Left side of the heart has two chambers, left atrium and left ventricle. Left atrium is a thin
walled and low pressure chamber. It receives oxygenated blood from the lungs through
pulmonary veins. This is the only exception in the body, where an artery carries venous
blood and vein carries the arterial blood.
LAYERS OF WALL OF THE HEART
Heart is made up of three layers of tissues:
1. Outer pericardium
2. Middle myocardium
3. Inner endocardium.
PERICARDIUM
Pericardium is the outer covering of the heart. It is made up of two layers:
i. Outer parietal pericardium - Parietal pericardium forms a strong protective sac for the
heart. It helps also to anchor the heart within the mediastinum.
ii. Inner visceral pericardium - Inner visceral pericardium lines the surface of
myocardium. It is made up of flattened epithelial cells. This layer is also known as
epicardium.
The space between the two layers is called pericardial cavity or pericardial space and it contains a
thin film of fluid.
MYOCARDIUM
2. Myocardium is the middle layer of wall of the heart and it is formed by cardiac muscle fibers or
cardiac myocytes. Myocardium forms the bulk of the heart and it is responsible for pumping action
of the heart. Unlike skeletal muscle fibers, the cardiac muscle fibers are involuntary in nature.
ENDOCARDIUM
Endocardium is the inner most layer of heart wall. It is a thin, smooth and glistening membrane. It
is formed by a single layer of endothelial cells, lining the inner surface of the heart. Endocardium
continues as endothelium of the blood vessels.
VALVES OF THE HEART
Two valves are in between atria and the ventricles called atrioventricular valves. Other two are the
semilunar valves, placed at the opening of blood vessels arising from ventricles, namely systemic
aorta and pulmonary artery. Valves of the heart permit the flow of blood through heart in only one
direction.
Atrioventricular Valves
3. Left atrioventricular valve is otherwise known as bicuspid valve. It is formed by two valvular
cusps. Right atrioventricular valve is known as tricuspid valve and it is formed by three cusps.
Cusps of the valves are attached to papillary muscles by means of chordate tendineae. Papillary
muscles play an important role in closure of the cusps and in preventing the back flow of blood
from ventricle to atria during ventricular contraction.
Semilunar Valves
Semilunar valves are present at the openings of systemic aorta and pulmonary artery and are
known as aortic valve and pulmonary valve respectively. Because of the half moon shape, these
two valves are called semilunar valves. Semilunar valves are made up of three flaps. Semilular
valves open only towards the aorta and pulmonary artery and prevent the backflow of blood into
the ventricles.
THREE MAIN TYPES OF BLOOD VESSELS:
Arteries. They begin with the aorta, the large artery leaving the heart. Arteries carry
oxygen-rich blood away from the heart to all of the body's tissues. They branch several
times, becoming smaller and smaller as they carry blood farther from the heart.
Capillaries. These are small, thin blood vessels that connect the arteries and the veins. Their
thin walls allow oxygen, nutrients, carbon dioxide, and other waste products to pass to and
from our organ's cells.
Veins. These are blood vessels that take blood back to the heart; this blood lacks oxygen
(oxygen-poor) and is rich in waste products that are to be excreted or removed from the
body. Veins become larger and larger as they get closer to the heart. The superior vena cava
is the large vein that brings blood from the head and arms to the heart, and the inferior vena
cava brings blood from the abdomen and legs into the heart.
BLOOD SUPPLY TO THE HEART
the right ventricle pumps the oxygen-poor blood to the lungs through the pulmonary valve. The
left atrium receives oxygen-rich blood from the lungs and pumps it to the left
ventricle through the mitral valve. The left ventricle pumps the oxygen-rich blood through the
aortic valve out to the rest of the body.
BRANCH OF AORTA
descending aorta: The region of the aorta that passes inferiorly towards the feet. it runs
from the heart down the length of the chest and abdomen. It is divided into two portions,
the thoracic and abdominal, in correspondence with the two great cavities of the trunk in
which it sits. Within the abdomen, the descending aorta branches into the two common
iliac arteries that provide blood to the pelvis and, eventually, the legs.
ascending aorta: The region of the aorta directly attached to the heart that passes
superiorly towards the head. The ascending aorta has two small branches, the left and
4. right coronary arteries. These arteries provide blood to the heart muscle, and their
blockage is the cause myocardial infarctions or heart attacks.
arch of the aorta: The region of the aorta that changes direction between the ascending
and descending aorta. the brachiocephalic artery, which itself divides into right common
carotid artery and the right subclavian artery, the left common carotid artery, and the left
subclavian artery. These arteries provide blood to both arms and the head.
1. abdominal aorta: The largest artery in the abdominal cavity. As part of the aorta,
it is a direct continuation of the descending aorta (of the thorax).
2. thoracic Aorta: Contained in the posterior mediastinal cavity, it begins at the
lower border of the fourth thoracic vertebra where it is continuous with the aortic
arch, and ends in front of the lower border of the twelfth thoracic vertebra, at the
aortic hiatus in the diaphragm where it becomes the abdominal aorta.
3. internal iliac arteries: Formed when the common iliac artery divides the internal
iliac artery at the vertebral level L5 descends inferiorly into the lesser pelvis.
CARDIAC CONDUCTION SYSTEM
the cardiac conduction system is a collection of nodes and specialised conduction cells that
initiate and co-ordinate contraction of the heart muscle. It consists of:
Sinoatrial node
Atrioventricular node
Atrioventricular bundle (bundle of His)
Purkinje fibres
Sinoatrial Node
5. The sinoatrial (SA) node is a collection of specialised cells (pacemaker cells), and is
located in the upper wall of the right atrium, at the junction where the superior vena cava
enters.
These pacemaker cells can spontaneously generate electrical impulses. The wave of
excitation created by the SA node spreads via gap junctions across both atria, resulting
in atrial contraction (atrial systole) – with blood moving from the atria into the ventricles.
Atrioventricular Node
After the electrical impulses spread across the atria, they converge at
the atrioventricular node – located within the atrioventricular septum, near the opening
of the coronary sinus.
The AV node acts to delay the impulses by approximately 120ms, to ensure the atria have
enough time to fully eject blood into the ventricles before ventricular systole.
The wave of excitation then passes from the atrioventricular node into the atrioventricular
bundle.
Atrioventricular Bundle
The atrioventricular bundle (bundle of His) is a continuation of the specialised tissue of
the AV node, and serves to transmit the electrical impulse from the AV node to the
Purkinje fibres of the ventricles.
It descends down the membranous part of the interventricular septum, before dividing
into two main bundles:
Right bundle branch – conducts the impulse to the Purkinje fibres of the right ventricle
Left bundle branch – conducts the impulse to the Purkinje fibres of the left ventricle
Purkinje Fibres
The Purkinje fibres (sub-endocardial plexus of conduction cells) are a network of
specialised cells. They are abundant with glycogen and have extensive gap junctions.
This rapid conduction allows coordinated ventricular contraction (ventricular systole)
and blood is moved from the right and left ventricles to the pulmonary artery and aorta
respectively.
6. cardiac cycle
EVENTS OF CARDIAC CYCLE
Events of cardiac cycle are classified into two:
1. Atrial events
2. Ventricular events.
atrial events
o atrial systole = 0.11 (0.1) sec
o atrial diastole = 0.69 (0.7) sec.
ventricular events
o ventricular systole = 0.27 (0.3) sec
o ventricular diastole = 0.53 (0.5) sec.
Atrial diastole Atria passively filling
Atrioventricular valves open
Atrial systole Action potential from the sinoatrial node (SAN)
Synchronous atrial contraction
Active filling of ventricles
7. Ventricular diastole Action potential from the sinoatrial node (SAN)
Synchronous atrial contraction
Active filling of ventricles
Ventricular systole Isovolumetric contraction – atrioventricular and semilunar valves are closed
Semilunar valve opens
Emptying of the ventricle
End-systolic volume
CARDIOVASCULAR DISORDERS
Angina pectoris - a condition marked by severe pain in the chest, often also spreading to the
shoulders, arms, and neck, owing to an inadequate blood supply to the heart.
myocardial infarction (MI) - commonly known as a heart attack, occurs when blood flow
decreases or stops to a part of the heart, causing damage to the heart muscle. The most common
symptom is chest pain or discomfort which may travel into the shoulder, arm, back, neck or jaw.
cardiac arrhythmia or heart arrhythmia – it is a group of conditions in which the heartbeat is
irregular, too fast, or too slow.The heart rate that is too fast – above 100 beats per minute in
adults – is called tachycardia, and a heart rate that is too slow – below 60 beats per minute – is
called bradycardia.
8. schemic heart disease- it is a condition of recurring chest pain or discomfort that occurs when a
part of the heart does not receive enough blood. This condition occurs most often during
exertion or excitement, when the heart requires greater blood flow.
DISORDER OF BLOOD VESSELS
Arteriosclerosis - occurs when the blood vessels that carry oxygen and nutrients from your heart
to the rest of your body (arteries) become thick and stiff, sometimes restricting blood flow to your
organs and tissues.
Atherosclerosis refers to the buildup of fats, cholesterol and other substances in and on your artery
walls (plaque), which can restrict blood flow.
Embolus - is often a small piece of a blood clot that impact in small vessel. The clot that travels
from the site where it formed to another location in the body.
Throbus - can lodge in a blood vessel and block the flow of blood in that location depriving
tissues of normal blood flow and oxygen.