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Mrs. Prajakta B. Kothawade
Assistant Professor,
PES Modern College of Pharmacy, for ladies, Moshi, Pune
Carbohydrates are Polyhydroxy aldehydes or ketones, or
substances that yield such compounds on hydrolysis.
General formula : (CH2O)n
• Monosaccharides – carbohydrates that cannot be hydrolyzed
to simpler carbohydrates; eg. Glucose or fructose.
• Oligosaccharides – carbohydrates that can be hydrolyzed into
a few monosaccharide units; eg. Sucrose or lactose
• Polysaccharides – carbohydrates that are polymeric sugars; eg
Starch or cellulose
• Monosaccharides Contains 3-9 carbon atom sugars.
Ketone Aldehyde
4 Tetrose Tetrulose
5 Pentose Pentulose
6 Hexose Hexulose
7 Heptose Heptulose
8 Octose Octulose
Number
of
carbons
• Oligosaccharides contains 2-10 monosaccharide units
joined by glycosidic bonds.
-OH group of one monosaccharide joined to -OH group
of another monosaccharide .
• Links may be a or b
• Link around glycosidic bond is fixed but anomeric forms
on the other C-1 are still in equilibrium.
Polysaccharides are complex carbohydrates made up
More than 10 linked monosaccharide units.
• Nomenclature:
Homopolysaccharide-a polysaccharide is made up of one type of
monosaccharide unit.
Heteropolysaccharide-a polysaccharide is made up of more than one type of
monosaccharide unit.
• Starch and glycogen are storage molecules
• Chitin and cellulose are structural molecules
• Cell surface polysaccharides are recognition molecules
Some types of polysaccharides
1.Starch
• Starch is a storage compound in plants, and made of
glucose units
• It is a homopolysaccharide made up of two components:
amylose and amylopectin.
• Most starch is 10-30% amylose and 70-90%
amylopectin
• Amylose – a straight chain structure formed by 1,4 glycosidic
bonds between α-D-glucose molecules.
H O
OH
H
OH
H
OH
CH2OH
H
O H
H
OH
H
OH
CH2OH
H
O
H
H H O
O
H
OH
H
OH
CH2OH
H
H H O
H
OH
H
OH
CH2OH
H
OH
H
H O
O
H
OH
H
OH
CH2OH
H
O
H
1
6
5
4
3
1
2
amylose
Structure of Amylose Fraction of Starch
• The amylose chain forms a
helix.
• This causes the blue colour
change on reaction with
iodine.
• Amylose is poorly soluble in
water, but forms micellar
suspensions
Amylose
Amylopectin-a glucose polymer with mainly α -(14)
linkages, but it also has branches formed by α -(16)
linkages. Branches are generally longer than shown above.
H O
OH
H
OH
H
OH
CH2OH
H
O H
H
OH
H
OH
CH2OH
H
O
H
H H O
O
H
OH
H
OH
CH2
H
H H O
H
OH
H
OH
CH2OH
H
OH
H
H O
O
H
OH
H
OH
CH2OH
H
O
H
O
1 4
6
H O
H
OH
H
OH
CH2OH
H
H H O
H
OH
H
OH
CH2OH
H
H
O
1
OH
3
4
5
2
amylopectin
Structure of Amylopectin Fraction of Starch
• Amylopectin causes a red-
violet colour change on
reaction with iodine.
• This change is usually
masked by the much
darker reaction of
amylose to iodine.
Amylopectin
Amylopectin
Starch therefore consists of amylose helices entangled on
branches of amylopectin.
2 Glycogen
• Storage polysaccharide in animals
• Glycogen constitutes up to 10% of liver mass and 1-2% of muscle
mass
• Glycogen is stored energy for the organism
• Similar in structure to amylopectin, only difference from starch:
number of branches
• Alpha(1,6) branches every 8-12 residues
• Like amylopectin, glycogen gives a red-violet color with iodine
glycogen
3 Cellulose
• The β-glucose molecules are joined by condensation, i.e. the
removal of water, forming β-(1,4) glycosidic linkages.
• The glucose units are linked into straight chains each 100-1000
units long.
Cellulose
4 pectin
Cell wall
polysaccharide
Carbohydrates.ppt

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Carbohydrates.ppt

  • 1. Mrs. Prajakta B. Kothawade Assistant Professor, PES Modern College of Pharmacy, for ladies, Moshi, Pune
  • 2. Carbohydrates are Polyhydroxy aldehydes or ketones, or substances that yield such compounds on hydrolysis. General formula : (CH2O)n
  • 3. • Monosaccharides – carbohydrates that cannot be hydrolyzed to simpler carbohydrates; eg. Glucose or fructose. • Oligosaccharides – carbohydrates that can be hydrolyzed into a few monosaccharide units; eg. Sucrose or lactose • Polysaccharides – carbohydrates that are polymeric sugars; eg Starch or cellulose
  • 4. • Monosaccharides Contains 3-9 carbon atom sugars.
  • 5.
  • 6.
  • 7. Ketone Aldehyde 4 Tetrose Tetrulose 5 Pentose Pentulose 6 Hexose Hexulose 7 Heptose Heptulose 8 Octose Octulose Number of carbons
  • 8. • Oligosaccharides contains 2-10 monosaccharide units joined by glycosidic bonds. -OH group of one monosaccharide joined to -OH group of another monosaccharide . • Links may be a or b • Link around glycosidic bond is fixed but anomeric forms on the other C-1 are still in equilibrium.
  • 9.
  • 10. Polysaccharides are complex carbohydrates made up More than 10 linked monosaccharide units. • Nomenclature: Homopolysaccharide-a polysaccharide is made up of one type of monosaccharide unit. Heteropolysaccharide-a polysaccharide is made up of more than one type of monosaccharide unit. • Starch and glycogen are storage molecules • Chitin and cellulose are structural molecules • Cell surface polysaccharides are recognition molecules
  • 11.
  • 12. Some types of polysaccharides 1.Starch • Starch is a storage compound in plants, and made of glucose units • It is a homopolysaccharide made up of two components: amylose and amylopectin. • Most starch is 10-30% amylose and 70-90% amylopectin
  • 13. • Amylose – a straight chain structure formed by 1,4 glycosidic bonds between α-D-glucose molecules. H O OH H OH H OH CH2OH H O H H OH H OH CH2OH H O H H H O O H OH H OH CH2OH H H H O H OH H OH CH2OH H OH H H O O H OH H OH CH2OH H O H 1 6 5 4 3 1 2 amylose Structure of Amylose Fraction of Starch
  • 14. • The amylose chain forms a helix. • This causes the blue colour change on reaction with iodine. • Amylose is poorly soluble in water, but forms micellar suspensions Amylose
  • 15. Amylopectin-a glucose polymer with mainly α -(14) linkages, but it also has branches formed by α -(16) linkages. Branches are generally longer than shown above. H O OH H OH H OH CH2OH H O H H OH H OH CH2OH H O H H H O O H OH H OH CH2 H H H O H OH H OH CH2OH H OH H H O O H OH H OH CH2OH H O H O 1 4 6 H O H OH H OH CH2OH H H H O H OH H OH CH2OH H H O 1 OH 3 4 5 2 amylopectin Structure of Amylopectin Fraction of Starch
  • 16. • Amylopectin causes a red- violet colour change on reaction with iodine. • This change is usually masked by the much darker reaction of amylose to iodine. Amylopectin Amylopectin
  • 17. Starch therefore consists of amylose helices entangled on branches of amylopectin.
  • 18. 2 Glycogen • Storage polysaccharide in animals • Glycogen constitutes up to 10% of liver mass and 1-2% of muscle mass • Glycogen is stored energy for the organism • Similar in structure to amylopectin, only difference from starch: number of branches • Alpha(1,6) branches every 8-12 residues • Like amylopectin, glycogen gives a red-violet color with iodine
  • 20. 3 Cellulose • The β-glucose molecules are joined by condensation, i.e. the removal of water, forming β-(1,4) glycosidic linkages. • The glucose units are linked into straight chains each 100-1000 units long.
  • 21.