Bromhidrosis

WHAT IT MEANS AND HOW WE CAN HELP
            OURSELVES
Definition of Bromhidrosis

   Bromhidrosis, also known as bromidrosis or body odor, is a common phenomenon in postpubertal
    individuals.
   In rare cases, bromhidrosis may become pathologic if it is particularly overpowering or if the
    bromhidrosis significantly interferes with the lives of the affected individuals.
   Bromhidrosis is a chronic condition in which excessive odor, usually an unpleasant one, emanates
    from the skin.
   Bromhidrosis, determined largely by apocrine gland secretion, can substantially
   impair a person's quality of life.




   http://emedicine.medscape.com/article/1072342-overview
   Retrieved April 7, 2011
Pathophysiology

   Eccrine Glands
       Distributed over the entire skin surface
       Eccrine Brom- May be caused by ingesting some foods including garlic, onion, curry,
       alcohol, penicillin, or underlying metabolic causes

    Apocrine Glands
      Limited distribution throughout axilla, genital skin, and breasts
      Odor due to bacterial decomposition of an oily fluid released from the apocrine glands
      Apocrine Brom- Most prevalent form of bromhidrosis

    Apoecrine glands
      Become apparent between the ages of 8 to 14 years. Contributes heavily to overall
      axillary sweating.

       http://emedicine.medscape.com/article/1072342-overview#a0104
One Interesting Fact


 **Findings show that eccrine glands are found in the
    dermis while apocrine glands are located in the
    subcutaneous tissue.




   http://emedicine.medscape.com/article/1072342-overview#a0104
The Effect of Hyperhidrosis on Bromhidrosis

 Hyperhidrosis may lead to bromhidrosis by creating
  a moist environment.

 Conversely, Hyperhidrosis may prevent
  bromhidrosis when excessive sweating washes away
  the odor causing bacteria.


http://emedicine.medscape.com/article/1072342-overview#a0199
Frequency of Diagnosis

   Frequency

 United States
   Bromhidrosis is generally considered rare. Although those with darker skin are
   more likely to suffer this condition.

 International
 The diagnosis of bromhidrosis is more common in many Asian countries
 In Asian countries minimal body odor is associated with personal distress, and can
  be diagnosed as bromhidrosis
 The social stigma of body odor leads more patients to seek treatment in these
  countries than in other countries


http://emedicine.medscape.com/article/1072342-overview#a0199
Race and Brom

    Race

 Apocrine bromhidrosis is believed to be more common in patients in dark-skinned ethnic
  groups than in others.
 In Asian patients, apocrine bromhidrosis may be associated with a positive family
  history.
 Eccrine bromhidrosis occurs in persons of all races.




    http://emedicine.medscape.com/article/1072342-overview#a0199
Sex and Age regarding Brom

Sex
    Bromhidrosis exhibits a male predominance, which may be a reflection of greater
    apocrine gland activity in men compared with women.


Age
 Axillary bromhidrosis depends on apocrine function and therefore manifests exclusively
  after puberty. It occurs only rarely in the elderly population.
 In contrast, eccrine bromhidrosis is more common than apocrine bromhidrosis during
  childhood, but it may occur at any age.


http://emedicine.medscape.com/article/1072342-overview#a0199
Physical Characteristics

Odor described as the following:
 Rancid
 Musty
 Pungent
 Sour


May occur as the following:
 Genital
 Plantar




http://emedicine.medscape.com/article/1072342-clinical
Brom and Metabolic Disorders

 Bromhidrosis is a metabolic and functional disease not typically associated with
   any anatomic disturbance.

 Therefore, results of physical examination of patients with axillary
   bromhidrosis are usually unremarkable.

 The skin appears normal most often, with a few exceptions.




http://emedicine.medscape.com/article/1072342-clinical#a0217
Causes of Brom

   Apocrine and eccrine gland sweating and the breakdown of bacteria

   Eccrine brom may be caused my metabolic disorders and disturbances in amino acid
    metabolism

   Ingestion of Certain Foods and Drugs
Let’s Discuss Ways to Manage It

 The International Hyperhidrosis Society may have some
 helpful hints although they often don’t address Brom in
 detail. Brochures available.

Bromhidrosis

  • 1.
    Bromhidrosis WHAT IT MEANSAND HOW WE CAN HELP OURSELVES
  • 2.
    Definition of Bromhidrosis  Bromhidrosis, also known as bromidrosis or body odor, is a common phenomenon in postpubertal individuals.  In rare cases, bromhidrosis may become pathologic if it is particularly overpowering or if the bromhidrosis significantly interferes with the lives of the affected individuals.  Bromhidrosis is a chronic condition in which excessive odor, usually an unpleasant one, emanates from the skin.  Bromhidrosis, determined largely by apocrine gland secretion, can substantially  impair a person's quality of life.  http://emedicine.medscape.com/article/1072342-overview  Retrieved April 7, 2011
  • 3.
    Pathophysiology  Eccrine Glands Distributed over the entire skin surface Eccrine Brom- May be caused by ingesting some foods including garlic, onion, curry, alcohol, penicillin, or underlying metabolic causes Apocrine Glands Limited distribution throughout axilla, genital skin, and breasts Odor due to bacterial decomposition of an oily fluid released from the apocrine glands Apocrine Brom- Most prevalent form of bromhidrosis Apoecrine glands Become apparent between the ages of 8 to 14 years. Contributes heavily to overall axillary sweating. http://emedicine.medscape.com/article/1072342-overview#a0104
  • 4.
    One Interesting Fact **Findings show that eccrine glands are found in the dermis while apocrine glands are located in the subcutaneous tissue.  http://emedicine.medscape.com/article/1072342-overview#a0104
  • 5.
    The Effect ofHyperhidrosis on Bromhidrosis  Hyperhidrosis may lead to bromhidrosis by creating a moist environment.  Conversely, Hyperhidrosis may prevent bromhidrosis when excessive sweating washes away the odor causing bacteria. http://emedicine.medscape.com/article/1072342-overview#a0199
  • 6.
    Frequency of Diagnosis Frequency  United States Bromhidrosis is generally considered rare. Although those with darker skin are more likely to suffer this condition.  International  The diagnosis of bromhidrosis is more common in many Asian countries  In Asian countries minimal body odor is associated with personal distress, and can be diagnosed as bromhidrosis  The social stigma of body odor leads more patients to seek treatment in these countries than in other countries http://emedicine.medscape.com/article/1072342-overview#a0199
  • 7.
    Race and Brom Race  Apocrine bromhidrosis is believed to be more common in patients in dark-skinned ethnic groups than in others.  In Asian patients, apocrine bromhidrosis may be associated with a positive family history.  Eccrine bromhidrosis occurs in persons of all races. http://emedicine.medscape.com/article/1072342-overview#a0199
  • 8.
    Sex and Ageregarding Brom Sex Bromhidrosis exhibits a male predominance, which may be a reflection of greater apocrine gland activity in men compared with women. Age  Axillary bromhidrosis depends on apocrine function and therefore manifests exclusively after puberty. It occurs only rarely in the elderly population.  In contrast, eccrine bromhidrosis is more common than apocrine bromhidrosis during childhood, but it may occur at any age. http://emedicine.medscape.com/article/1072342-overview#a0199
  • 9.
    Physical Characteristics Odor describedas the following:  Rancid  Musty  Pungent  Sour May occur as the following:  Genital  Plantar http://emedicine.medscape.com/article/1072342-clinical
  • 10.
    Brom and MetabolicDisorders  Bromhidrosis is a metabolic and functional disease not typically associated with any anatomic disturbance.  Therefore, results of physical examination of patients with axillary bromhidrosis are usually unremarkable.  The skin appears normal most often, with a few exceptions. http://emedicine.medscape.com/article/1072342-clinical#a0217
  • 11.
    Causes of Brom  Apocrine and eccrine gland sweating and the breakdown of bacteria  Eccrine brom may be caused my metabolic disorders and disturbances in amino acid metabolism  Ingestion of Certain Foods and Drugs
  • 12.
    Let’s Discuss Waysto Manage It  The International Hyperhidrosis Society may have some helpful hints although they often don’t address Brom in detail. Brochures available.