This chapter discusses how physical laws and the environment constrain animal size and shape. It introduces key concepts around form and function relationships in animals. These include how different tissues (epithelial, connective, muscle, and nervous) relate to an animal's functions. The chapter also covers bioenergetics and how animals obtain and use energy. A major topic is homeostasis, how animals regulate internal conditions, comparing endothermic and ectothermic strategies. Thermoregulation mechanisms like insulation, circulation and behavior are examined.