TRACKING THE CORONAVIRUSBIOLOGY OF SARS-COV-2: INFECTION

1. TRACKING THE CORONAVIRUS
BIOLOGY OF SARS-COV-2: INFECTION
Prepared by
Yousef Elshrek

2. • This is the virus SARS-CoV-2.
• Its name stands for Severe Acute
Respiratory Syndrome Coronavirus 2.
• You may have heard it called just the
coronavirus, or COVID-19.

3. • Coronaviruses are actually a family
of viruses that include SARS-CoV-
2, and COVID-19 is the name of
the disease caused by it.
• Coronaviruses infect humans and
other animals

4. • In humans, they cause the
common cold and, in some
cases, more serious respiratory
diseases.

5. • All coronaviruses, including SARS-
CoV-2, have a genome made of a
single strand of RNA which is
surrounded by a membrane made of
lipids and proteins.

6. • This membrane is called an envelope.
https://medicine.umich.edu/sites/default/files/images/shared/800px3D_medical_animation_corona_virus_0.jpg

7. • Coronaviruses are named
after what looks like a crown
of protein spikes that stick
out of their envelope.
https://i.ncdn.xyz/publisherc1a3f893382d2b2f8a9aa22a654d9c97/2020/01/491cfb3562fc6046e76f8d6a7f37328c.jpg=s660

8. • Coronaviruses enter the body mainly through the mouth or nose.
• The virus then has to get inside a human cell.

9. • The protein spikes in the
virus's envelope attach to
specific proteins on the
surface of a cell.

10. • This causes the virus's membrane to fuse with the cell's membrane, releasing
the virus's RNA genome into the cell.

11. • The cell's ribosomes translate the virus's RNA into proteins, including
viral RNA polymerase.

12. • The RNA polymerase
transcribes the virus's RNA,
making more RNA copies that
are translated into proteins.
• It also makes more copies of the
virus's whole genome.

13. • The new viral genome and proteins combine to make a new virus that is
packaged into an envelope formed from the cells, membranes.

14. • Newly-formed viruses travel to the cell’s
• surface and are released outside the cell.

15. • These viruses can infect other cells or leave the body in mucus and saliva
droplets.
• This can all happen even if a person doesn't feel sick or show symptoms
of disease.
• A fever or coughing are usually signs, that the immune system is fighting
the infection.
• The production of new viruses continues until the body's immune system
can eliminate the infection.

16. • REFERENCES
• https://i.ncdn.xyz/publisherc1a3f893382d2b2f8a9aa22a654d9c97/20
20/01/491cfb3562fc6046e76f8d6a7f37328c.jpg=s660
• https://medicine.umich.edu/sites/default/files/images/shared/800px
3D_medical_animation_corona_virus_0.jpg
• https://www.youtube.com/watch?v=LoVJCx6XXMM