This document provides a biography for Dr. Soundar Divakar including his educational background, professional experience, research areas, publications, patents, and awards. It summarizes that he has a Ph.D. in Chemistry, has worked in research areas including NMR studies of biomolecules, cyclodextrin chemistry, and enzyme catalyzed transformations. He has over 150 publications and 29 patents in these areas and has received awards for his scientific work.
1 ijfaf oct-2017-4-the characteristics of rumenAI Publications
The ruminant animal feed ingredients consisting of forage with the combination of grass and legume which were almost limited in availability, the cocoa leaves as agricultural wastes or wastes containing low nutrient plantation low used as alternative feed ingredients. To overcome these problems required a simple technology that is fermentation using microorganisms indigenus so that the effluent quality cocoa can be improved. Indigenus microorganisms were microbes that exist in individuals without disturbing the activities. The purpose of this research was to improve the quality of rumen fluid characteristics and digestibility of cocoa leaves fermented by microorganisms indigenus. The method used in this study was completely randomized design factorial with three replications, treatment factors consist of A as the level of microbes (A1 = 5%, A2 = 10%, A3 = 15%) and factor B as the duration of fermentation (B1 = 2 day, B2 = 4 days, B3 = 6 days) and the variables; the nutrient content and digestibility of cocoa leaves before and after being fermented and the characteristics of rumen fluid in vitro methods. The results showed that the increasing levels of use of microbes and fermentation time can enhance the quality of cocoa leaves that reduce the content of dry material from 31.389 to 25.488% and increase the protein content of the coarse 6.153 to 7.483%. Dry Material digestibility increased from 27.379 to 32.942% and 27.432% Protein 21,435- rough. Rumen fluid characteristics were rumen fluid pH ranges from 7.427 to 7.603, NH3 production ranges from 16.820 - 19,975mg / 100ml, and Volatyl Fatty Acid production from 83.667 to 101.000 mM. The conclusion that increasing the digestibility quality cocoa fruit leather could be made by fermentation by microorganisms indigenus.
IRJET- Hydrothermal Pretreatment Enhanced Enzymatic Hydrolysis and Glucose Pr...IRJET Journal
This document summarizes a study that investigated the use of hydrothermal pretreatment to enhance the enzymatic hydrolysis and glucose production from lignocellulosic biomass. Specifically:
- Sawdust samples from hardwood and softwood were treated with sodium hydroxide solution at 80±5°C for varying times. The 180 minute treatment yielded the highest cellulose content (84.9% for hardwood, 83.5% for softwood) and lowest lignin content.
- The pretreated samples were then hydrolyzed with crude enzymes from Trichoderma and Aspergillus niger fungi. The maximum glucose yields were 7.4% and 6% respectively.
- Total solid
Immobilization of Glucose oxidase on PANI-2 Amino Pyridine composite film by ...iosrjce
IOSR Journal of Applied Chemistry (IOSR-JAC) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of applied chemistry and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications in Chemical Science. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Transcript Level of Genes Involved in “Rebaudioside A” Biosynthesis Pathway u...Premier Publishers
Stevia rebaudiana Bertoni is a plant which has recently been used widely as a sweetener. This medicinal plant has some components such as diterpenoid glycosides called steviol glycosides [SGs]. Rebaudioside A is a diterpenoid steviol glycoside which is 300 times sweeter than table sugar. This study was done to investigate the effect of GA3 (50 mg/L) on the expression of 14 genes involved in Rebaudioside A biosynthesis pathway in Stevia rebaudiana under in vitro conditions. The expression of DXS remarkably decreased by day 3. Also, probably because of the negative feedback of GA3 on MEP-drived isoprenes, GGDS transcript level reached its lowest amount after GA3 treatment. The abundance of DXR, CMS, CMK, MCS, and CDPS transcripts showed a significant increase at various days after this treatment. A significant drop in the expression levels of KS and UGT85C2 is detected during the first day. However, expression changes of HDR and KD were not remarkable. Results revealed that the level of transcript of UGT74G1 and UGT76G1 up regulated significantly 4 and 2 times higher than control, respectively. However, more research needs to shed more light on the mechanism of GA3 on gene expression of MEP pathway.
Microbial Processing of Agricultural Wastes to produce Pectinase Enzyme(s) an...Meesha Singh
Microbial Processing of Agricultural Wastes to produce Pectinase Enzyme(s) and Evaluation of their Industrial Applications
This document summarizes a study on the production of pectinase enzymes from agricultural wastes using microbial processing. Pectinases are important industrial enzymes with applications in juice extraction and clarification. The study aims to optimize pectinase production from bacterial sources using agricultural waste, characterize the enzymes, and evaluate their applications. Key steps include screening bacteria, optimizing fermentation parameters, purifying and characterizing the enzymes, and testing applications in juice clarification and fruit peeling. A hierarchical model is also developed to analyze barriers to industrial pectinase production.
This document discusses medium optimization and antioxidant activity of exopolysaccharide produced by Bacillus subtilis. Bacillus subtilis was isolated from soil and used to produce exopolysaccharide. Statistical methods like Plackett-Burman design and response surface methodology using central composite design were used to optimize the culture medium. The optimized medium contained specific concentrations of cane molasses, yeast extract, NaCl, and CaCl2, which produced 4.92 g/L of exopolysaccharide. The exopolysaccharide showed antioxidant activity, with a 61.19% reduction of DPPH free radicals, greater than vitamin C. The biopolymer could have applications in industries and pharmaceuticals.
1 ijfaf oct-2017-4-the characteristics of rumenAI Publications
The ruminant animal feed ingredients consisting of forage with the combination of grass and legume which were almost limited in availability, the cocoa leaves as agricultural wastes or wastes containing low nutrient plantation low used as alternative feed ingredients. To overcome these problems required a simple technology that is fermentation using microorganisms indigenus so that the effluent quality cocoa can be improved. Indigenus microorganisms were microbes that exist in individuals without disturbing the activities. The purpose of this research was to improve the quality of rumen fluid characteristics and digestibility of cocoa leaves fermented by microorganisms indigenus. The method used in this study was completely randomized design factorial with three replications, treatment factors consist of A as the level of microbes (A1 = 5%, A2 = 10%, A3 = 15%) and factor B as the duration of fermentation (B1 = 2 day, B2 = 4 days, B3 = 6 days) and the variables; the nutrient content and digestibility of cocoa leaves before and after being fermented and the characteristics of rumen fluid in vitro methods. The results showed that the increasing levels of use of microbes and fermentation time can enhance the quality of cocoa leaves that reduce the content of dry material from 31.389 to 25.488% and increase the protein content of the coarse 6.153 to 7.483%. Dry Material digestibility increased from 27.379 to 32.942% and 27.432% Protein 21,435- rough. Rumen fluid characteristics were rumen fluid pH ranges from 7.427 to 7.603, NH3 production ranges from 16.820 - 19,975mg / 100ml, and Volatyl Fatty Acid production from 83.667 to 101.000 mM. The conclusion that increasing the digestibility quality cocoa fruit leather could be made by fermentation by microorganisms indigenus.
IRJET- Hydrothermal Pretreatment Enhanced Enzymatic Hydrolysis and Glucose Pr...IRJET Journal
This document summarizes a study that investigated the use of hydrothermal pretreatment to enhance the enzymatic hydrolysis and glucose production from lignocellulosic biomass. Specifically:
- Sawdust samples from hardwood and softwood were treated with sodium hydroxide solution at 80±5°C for varying times. The 180 minute treatment yielded the highest cellulose content (84.9% for hardwood, 83.5% for softwood) and lowest lignin content.
- The pretreated samples were then hydrolyzed with crude enzymes from Trichoderma and Aspergillus niger fungi. The maximum glucose yields were 7.4% and 6% respectively.
- Total solid
Immobilization of Glucose oxidase on PANI-2 Amino Pyridine composite film by ...iosrjce
IOSR Journal of Applied Chemistry (IOSR-JAC) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of applied chemistry and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications in Chemical Science. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Transcript Level of Genes Involved in “Rebaudioside A” Biosynthesis Pathway u...Premier Publishers
Stevia rebaudiana Bertoni is a plant which has recently been used widely as a sweetener. This medicinal plant has some components such as diterpenoid glycosides called steviol glycosides [SGs]. Rebaudioside A is a diterpenoid steviol glycoside which is 300 times sweeter than table sugar. This study was done to investigate the effect of GA3 (50 mg/L) on the expression of 14 genes involved in Rebaudioside A biosynthesis pathway in Stevia rebaudiana under in vitro conditions. The expression of DXS remarkably decreased by day 3. Also, probably because of the negative feedback of GA3 on MEP-drived isoprenes, GGDS transcript level reached its lowest amount after GA3 treatment. The abundance of DXR, CMS, CMK, MCS, and CDPS transcripts showed a significant increase at various days after this treatment. A significant drop in the expression levels of KS and UGT85C2 is detected during the first day. However, expression changes of HDR and KD were not remarkable. Results revealed that the level of transcript of UGT74G1 and UGT76G1 up regulated significantly 4 and 2 times higher than control, respectively. However, more research needs to shed more light on the mechanism of GA3 on gene expression of MEP pathway.
Microbial Processing of Agricultural Wastes to produce Pectinase Enzyme(s) an...Meesha Singh
Microbial Processing of Agricultural Wastes to produce Pectinase Enzyme(s) and Evaluation of their Industrial Applications
This document summarizes a study on the production of pectinase enzymes from agricultural wastes using microbial processing. Pectinases are important industrial enzymes with applications in juice extraction and clarification. The study aims to optimize pectinase production from bacterial sources using agricultural waste, characterize the enzymes, and evaluate their applications. Key steps include screening bacteria, optimizing fermentation parameters, purifying and characterizing the enzymes, and testing applications in juice clarification and fruit peeling. A hierarchical model is also developed to analyze barriers to industrial pectinase production.
This document discusses medium optimization and antioxidant activity of exopolysaccharide produced by Bacillus subtilis. Bacillus subtilis was isolated from soil and used to produce exopolysaccharide. Statistical methods like Plackett-Burman design and response surface methodology using central composite design were used to optimize the culture medium. The optimized medium contained specific concentrations of cane molasses, yeast extract, NaCl, and CaCl2, which produced 4.92 g/L of exopolysaccharide. The exopolysaccharide showed antioxidant activity, with a 61.19% reduction of DPPH free radicals, greater than vitamin C. The biopolymer could have applications in industries and pharmaceuticals.
Role of polyamine in post harvest management of fruitsPraveen Mishra
This document discusses the role of polyamines (PAs) in post-harvest management of fruit crops. It defines PAs as positively charged nitrogenous compounds derived from amino acids that are important for numerous post-harvest processes. Common PAs in plants include putrescine, spermidine, and spermine. The document outlines how PAs can inhibit ethylene biosynthesis, reduce respiration rate, increase firmness, reduce chilling injury and weight loss, retard color changes, and maintain antioxidant enzyme activity in fruits, helping to delay senescence. Both endogenous and exogenous application of PAs are shown to suppress ethylene production and significantly increase the shelf life of fruits.
This document summarizes a study assessing genetic diversity in 25 spinach accessions using SDS-PAGE and morphological analysis. Morphological analysis found variation in seed shape, color, stem color, and leaf tips. SDS-PAGE identified 27 total protein bands, with 20 being polymorphic. Three accessions from different locations (20541 from Peshawar, 19902 from AVRDC, and 20180 from Lahore) showed significant genetic differences based on presence of distinct protein bands. While genetic differences were linked to morphological variations, no clear linkage was found between diversity and geographic origin of the accessions. The study concluded spinach accessions show genetic diversity that could benefit future breeding programs.
This document appears to be a report from Dr. Fikret Koc of the Chemistry Department summarizing the work of a student, Nabeel B Azeez, involving the synthesis of organic compounds including diols, carbamates, dihydropyridones, selenides, thiocarbamates, acetals, aminodiols and lactams through reactions such as Michael additions and manipulations of functional groups. The student synthesized a variety of complex organic molecules and intermediates for further use in organic chemistry.
Antioxidant potential of various fractions of Launaea pinnatifida leaves and ...Himanshu Makwana
According to the Ayurvedic literature Launaea pinnatifida Cass is belong to the class of controversial drug Gohjiva. This plant is well known and valuable herb as per the traditional and Ethnobotanical information. Leaves of this plant has been used since ancient time as herbal remedy for jaundice, diuretic, blood purifier and hepatoprotective action by the tribal people of the Western Ghats. However, the plant remains largely unexplored. The antioxidant capacity of the various fraction of L. Pinnatifida leaves and roots extracts, obtained by successive solvent extraction with various polarity of solvents namely Pet. Ether, Chloroform, Methanol and Water, was evaluated by means of different In vitro methods; DPPH radical scavenging activity (IC50 value for standard ascorbic acid and L. pinnatifida leaves methanol fraction was 165.8 and 220.3 respectively), Ferric ion reducing antioxidant power assay (FRAP) and total antioxidant capacity (TAC) by Phosphomolybdenum method. Those findings means that L. Pinnatifida leaves methanol fraction was most active fraction for free radical scavenging activity compared to all other fractions hence consider as a most potent fraction for the isolation of phytochemical also used in a food industry for protection against oxidative damage. Antioxidant results also support the traditional claim of this plant. The strongest antioxidant activity of methanol fractions of leaves could be due to the presence of flavonoids and phenols.
Ramprasad Ghosh is seeking a research position in bioorganic/medicinal chemistry. He has a PhD in organic chemistry from the Indian Institute of Chemical Biology and has held three postdoctoral research positions. His research has focused on the synthesis of carbohydrates, nucleosides, and glycoconjugates for applications in drug delivery and enzyme inhibition. Currently he is working on synthesizing derivatives of glucosamine-6-phosphate to target bacterial riboswitches and develop new antibiotics.
Extraction of Pectin from Unripe Banana PeelIRJET Journal
This document describes a study that extracted pectin from unripe banana peels through an acid extraction process. Pectin was extracted from unripe banana peel powder using hydrochloric acid at 90±5°C for varying time periods. Extraction for 4 hours at 90°C and pH 2 yielded the highest amount of pectin at 13%. The extracted pectin was characterized based on parameters like moisture content, ash content, and degree of esterification. Fourier transform infrared spectroscopy analysis confirmed the chemical structure of the extracted pectin. The pectin extracted from banana peels has potential applications as a gelling agent in food products.
Isolation and characterization of Lignin-degrading microbestarun shekhawat
This document appears to be a student's thesis proposal on isolating and characterizing lignin-degrading microbes. It includes an abstract stating the aim is to identify bacteria and fungi with high potential for degrading lignocellulose compounds. The introduction provides background on lignin and current lignin degradation research. The literature review covers the chemical composition of lignocellulose and its degradation, including details on cellulose, hemicellulose, and lignin breakdown enzymes like lignin peroxidase and manganese peroxidase produced by fungi. The proposal seems to focus on isolating microbes from paper/pulp industry effluent and soil that can degrade lignin as measured by laccase and lignin peroxidase assays.
Chitosan is derived from chitin, which is found in the exoskeleton of crustaceans. Chitosan nanoparticles can be synthesized through a process involving deacetylation of chitin with sodium hydroxide. Chitosan has a variety of applications including in photography, cosmetics, as artificial skin, surgical dressings, food and nutrition supplements, ophthalmology, water remediation, textile dye removal, paper finishing, batteries, fluorescence, drug delivery, pharmaceutical tablets, and can be modified to improve its properties.
Research from a bacterium bacillus subtilis b 3157 by fabAlexander Decker
This document discusses research into the biosynthetic pathways that produce 2H-labeled inosine in the bacterium Bacillus subtilis B-3157. The bacterium was grown in heavy water medium containing a hydrolysate of deuterated biomass as a source of 2H-labeled substrates. Isolation and analysis of the produced 2H-labeled inosine found incorporation of 5 deuterium atoms, with 3 in the ribose residue and 2 in the hypoxanthine residue. The non-exchangeable deuterium atoms in ribose originated from HMP shunt reactions, while the atoms in hypoxanthine came from [2H]amino acids in the growth medium.
Chitin and chitosan are natural polymers that have many potential industrial and biomedical applications. Chitin is found in the exoskeleton of crustaceans and insects, while chitosan is produced commercially by deacetylation of chitin. Both polymers are biodegradable and biocompatible. This document reviews the chemistry, properties and processing methods of chitin and chitosan. It also summarizes recent research on derivatives of these polymers and their various applications, including uses in biomedical areas such as drug delivery, wound healing and cancer therapy.
1. The study examined the effects of different concentrations of cobalt (50, 100, 150, 200, and 250 mg/kg soil) on biochemical constituents and antioxidant enzyme activities in the green gram plant Vigna radiata.
2. Biochemicals like sugars, starch, amino acids, and proteins decreased with increasing cobalt concentration, while antioxidant enzymes like catalase decreased but peroxidase and polyphenol oxidase increased.
3. The 50 mg/kg cobalt level benefited plant growth and biochemical/antioxidant parameters compared to higher concentrations and the control, suggesting it acts as a beneficial trace element at low levels.
Molecular Characterization of Isolated Methyl Parathion Degrading Bacteria an...IJSRD
The burning problem in present era is pesticide residue in fruits and foods. present study focus on degradation of pesticide in contest to that total 45 methyl parathion(MP) degrading bacteria were isolated from sludge of MP producing industrial waste. According to screening 21 highly efficient pesticide degraders were selected at 500ppm concentration of standard methyl parathion as a sole carbon source. All isolates were characterized by RAPD and based on the RAPD result all 21 bacterial isolates were grouped in to 2 main clusters with 58% similarity. Characterization of MP degrading gene was carried out by using specific primer. Out of 21 isolates, 14 isolates were containing mpd gene and 4 isolates were containing opd gene while remaining 3 isolates which did not show amplification with opd/ mpd primer so it may contain other unreported gene responsible for methyl parathion degradation. Isolates were identified based on 16s rRNA sequence and one highly efficient bacterium selected for genome characterization.
The document discusses biopolymers, which are polymers produced by living organisms. It covers various types of biodegradable polymers including synthetic polymers like polylactic acid (PLA) and natural polymers like starch. The mechanisms of polymer biodegradation are described. Applications of biodegradable polymers in areas like biomedical, packaging and agriculture are also mentioned. Factors affecting the biodegradation of polymers are discussed. Current trends in biopolymers including their use as alternatives to petroleum-based plastics are summarized.
Solubilisation of Quinazoline drugs by using Beta cyclodextrin complex formationRavindra Zirmire
Solubility of the Quinazoline related drugs was enhanced by usind complex formation method,and the Physico chemical characterisation of these drugs was carried out by simplest methods as UV spectroscopy,TLC,FTIR Spectroscopy.
This document summarizes a student's engineering project involving the 1,2-propanediol utilization microcompartment (PDU MCP) in bacteria. The student manipulated the genetic code of bacterial cells to engineer signal sequences on the PDU MCP. Methods included growing bacteria on 1,2-propanediol, using homologous recombination, sequencing, and microscopy. Results showed amplification of the pduD gene to expected sizes. Future applications may include engineering MCPs for use as nanobioreactors in industry by modifying the PduD N-terminus and increasing MCP size and number of localized enzymes.
This document describes a project report submitted by students for their Bachelor of Engineering degree in Biotechnology. The project aimed to optimize the production media components for Sclerotiorin production from Penicillium sclerotorium using a Plackett-Burman experimental design. Sclerotiorin is a metabolite produced by Penicillium sclerotorium that has various biological activities but is currently very expensive due to low production yields. The students analyzed Sclerotiorin production under different media conditions and identified the most important components for high yield production.
Chitin and chitosan source, chemistry, general method of preparation and thei...Hridoy Hridoy
This presentation introduces chitin and chitosan, their sources, chemistry, extraction methods, and applications in the food industry. Chitin is a naturally occurring polysaccharide found in fungi, arthropod exoskeletons, and some other organisms. Chitosan is produced by deacetylating chitin using alkaline substances. Major sources of chitin include crab and shrimp shells. Extraction methods can be chemical, involving demineralization, deprotienization, and decolorization, or biological using lactic acid bacteria. Applications of chitin and chitosan in food include use in edible films, as dietary fiber, antioxidants, preservatives, dye binding, and
The document discusses the production of polyglutamic acid (PGA) by Bacillus subtilis isolates. Key points:
- Sixty-eight B. subtilis isolates were obtained from sugarcane fields, seawater, and marshes water, of which 21 could produce PGA. The highest PGA yields were obtained using isolates SC10 and SW5 in modified media.
- PGA was purified through various steps and identified using tests like ninhydrin, TLC, and spectroscopy. Molecular weights of PGA ranged from 97-131 kDa.
- Hydrogels were formed by treating PGA with gamma rays, alpha rays, beta rays and neutrons, with
Preparation of pyrimido[4,5 b][1,6]naphthyridin-4(1 h)-one derivativeselshimaa eid
This document describes the preparation of pyrimido[4,5-b][1,6]naphthyridin-4(1H)-one derivatives using a zeolite-nanogold catalyst. An efficient one-pot synthesis is developed involving the cyclocondensation of 6-amino-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, aromatic aldehydes, and 1-benzylpiperidin-4-one in ethanol at 80°C. The nanogold catalyst is characterized and found to contain 4-6 nm gold nanoparticles dispersed on zeolite. Several derivatives are synthesized in good yields and characterized. Molecular dock
Induced mutational studies on saccharomyces cerevisiae for bioethanol product...eSAT Publishing House
IJRET : International Journal of Research in Engineering and Technology is an international peer reviewed, online journal published by eSAT Publishing House for the enhancement of research in various disciplines of Engineering and Technology. The aim and scope of the journal is to provide an academic medium and an important reference for the advancement and dissemination of research results that support high-level learning, teaching and research in the fields of Engineering and Technology. We bring together Scientists, Academician, Field Engineers, Scholars and Students of related fields of Engineering and Technology
International Journal of Engineering Research and Applications (IJERA) is an open access online peer reviewed international journal that publishes research and review articles in the fields of Computer Science, Neural Networks, Electrical Engineering, Software Engineering, Information Technology, Mechanical Engineering, Chemical Engineering, Plastic Engineering, Food Technology, Textile Engineering, Nano Technology & science, Power Electronics, Electronics & Communication Engineering, Computational mathematics, Image processing, Civil Engineering, Structural Engineering, Environmental Engineering, VLSI Testing & Low Power VLSI Design etc.
Role of polyamine in post harvest management of fruitsPraveen Mishra
This document discusses the role of polyamines (PAs) in post-harvest management of fruit crops. It defines PAs as positively charged nitrogenous compounds derived from amino acids that are important for numerous post-harvest processes. Common PAs in plants include putrescine, spermidine, and spermine. The document outlines how PAs can inhibit ethylene biosynthesis, reduce respiration rate, increase firmness, reduce chilling injury and weight loss, retard color changes, and maintain antioxidant enzyme activity in fruits, helping to delay senescence. Both endogenous and exogenous application of PAs are shown to suppress ethylene production and significantly increase the shelf life of fruits.
This document summarizes a study assessing genetic diversity in 25 spinach accessions using SDS-PAGE and morphological analysis. Morphological analysis found variation in seed shape, color, stem color, and leaf tips. SDS-PAGE identified 27 total protein bands, with 20 being polymorphic. Three accessions from different locations (20541 from Peshawar, 19902 from AVRDC, and 20180 from Lahore) showed significant genetic differences based on presence of distinct protein bands. While genetic differences were linked to morphological variations, no clear linkage was found between diversity and geographic origin of the accessions. The study concluded spinach accessions show genetic diversity that could benefit future breeding programs.
This document appears to be a report from Dr. Fikret Koc of the Chemistry Department summarizing the work of a student, Nabeel B Azeez, involving the synthesis of organic compounds including diols, carbamates, dihydropyridones, selenides, thiocarbamates, acetals, aminodiols and lactams through reactions such as Michael additions and manipulations of functional groups. The student synthesized a variety of complex organic molecules and intermediates for further use in organic chemistry.
Antioxidant potential of various fractions of Launaea pinnatifida leaves and ...Himanshu Makwana
According to the Ayurvedic literature Launaea pinnatifida Cass is belong to the class of controversial drug Gohjiva. This plant is well known and valuable herb as per the traditional and Ethnobotanical information. Leaves of this plant has been used since ancient time as herbal remedy for jaundice, diuretic, blood purifier and hepatoprotective action by the tribal people of the Western Ghats. However, the plant remains largely unexplored. The antioxidant capacity of the various fraction of L. Pinnatifida leaves and roots extracts, obtained by successive solvent extraction with various polarity of solvents namely Pet. Ether, Chloroform, Methanol and Water, was evaluated by means of different In vitro methods; DPPH radical scavenging activity (IC50 value for standard ascorbic acid and L. pinnatifida leaves methanol fraction was 165.8 and 220.3 respectively), Ferric ion reducing antioxidant power assay (FRAP) and total antioxidant capacity (TAC) by Phosphomolybdenum method. Those findings means that L. Pinnatifida leaves methanol fraction was most active fraction for free radical scavenging activity compared to all other fractions hence consider as a most potent fraction for the isolation of phytochemical also used in a food industry for protection against oxidative damage. Antioxidant results also support the traditional claim of this plant. The strongest antioxidant activity of methanol fractions of leaves could be due to the presence of flavonoids and phenols.
Ramprasad Ghosh is seeking a research position in bioorganic/medicinal chemistry. He has a PhD in organic chemistry from the Indian Institute of Chemical Biology and has held three postdoctoral research positions. His research has focused on the synthesis of carbohydrates, nucleosides, and glycoconjugates for applications in drug delivery and enzyme inhibition. Currently he is working on synthesizing derivatives of glucosamine-6-phosphate to target bacterial riboswitches and develop new antibiotics.
Extraction of Pectin from Unripe Banana PeelIRJET Journal
This document describes a study that extracted pectin from unripe banana peels through an acid extraction process. Pectin was extracted from unripe banana peel powder using hydrochloric acid at 90±5°C for varying time periods. Extraction for 4 hours at 90°C and pH 2 yielded the highest amount of pectin at 13%. The extracted pectin was characterized based on parameters like moisture content, ash content, and degree of esterification. Fourier transform infrared spectroscopy analysis confirmed the chemical structure of the extracted pectin. The pectin extracted from banana peels has potential applications as a gelling agent in food products.
Isolation and characterization of Lignin-degrading microbestarun shekhawat
This document appears to be a student's thesis proposal on isolating and characterizing lignin-degrading microbes. It includes an abstract stating the aim is to identify bacteria and fungi with high potential for degrading lignocellulose compounds. The introduction provides background on lignin and current lignin degradation research. The literature review covers the chemical composition of lignocellulose and its degradation, including details on cellulose, hemicellulose, and lignin breakdown enzymes like lignin peroxidase and manganese peroxidase produced by fungi. The proposal seems to focus on isolating microbes from paper/pulp industry effluent and soil that can degrade lignin as measured by laccase and lignin peroxidase assays.
Chitosan is derived from chitin, which is found in the exoskeleton of crustaceans. Chitosan nanoparticles can be synthesized through a process involving deacetylation of chitin with sodium hydroxide. Chitosan has a variety of applications including in photography, cosmetics, as artificial skin, surgical dressings, food and nutrition supplements, ophthalmology, water remediation, textile dye removal, paper finishing, batteries, fluorescence, drug delivery, pharmaceutical tablets, and can be modified to improve its properties.
Research from a bacterium bacillus subtilis b 3157 by fabAlexander Decker
This document discusses research into the biosynthetic pathways that produce 2H-labeled inosine in the bacterium Bacillus subtilis B-3157. The bacterium was grown in heavy water medium containing a hydrolysate of deuterated biomass as a source of 2H-labeled substrates. Isolation and analysis of the produced 2H-labeled inosine found incorporation of 5 deuterium atoms, with 3 in the ribose residue and 2 in the hypoxanthine residue. The non-exchangeable deuterium atoms in ribose originated from HMP shunt reactions, while the atoms in hypoxanthine came from [2H]amino acids in the growth medium.
Chitin and chitosan are natural polymers that have many potential industrial and biomedical applications. Chitin is found in the exoskeleton of crustaceans and insects, while chitosan is produced commercially by deacetylation of chitin. Both polymers are biodegradable and biocompatible. This document reviews the chemistry, properties and processing methods of chitin and chitosan. It also summarizes recent research on derivatives of these polymers and their various applications, including uses in biomedical areas such as drug delivery, wound healing and cancer therapy.
1. The study examined the effects of different concentrations of cobalt (50, 100, 150, 200, and 250 mg/kg soil) on biochemical constituents and antioxidant enzyme activities in the green gram plant Vigna radiata.
2. Biochemicals like sugars, starch, amino acids, and proteins decreased with increasing cobalt concentration, while antioxidant enzymes like catalase decreased but peroxidase and polyphenol oxidase increased.
3. The 50 mg/kg cobalt level benefited plant growth and biochemical/antioxidant parameters compared to higher concentrations and the control, suggesting it acts as a beneficial trace element at low levels.
Molecular Characterization of Isolated Methyl Parathion Degrading Bacteria an...IJSRD
The burning problem in present era is pesticide residue in fruits and foods. present study focus on degradation of pesticide in contest to that total 45 methyl parathion(MP) degrading bacteria were isolated from sludge of MP producing industrial waste. According to screening 21 highly efficient pesticide degraders were selected at 500ppm concentration of standard methyl parathion as a sole carbon source. All isolates were characterized by RAPD and based on the RAPD result all 21 bacterial isolates were grouped in to 2 main clusters with 58% similarity. Characterization of MP degrading gene was carried out by using specific primer. Out of 21 isolates, 14 isolates were containing mpd gene and 4 isolates were containing opd gene while remaining 3 isolates which did not show amplification with opd/ mpd primer so it may contain other unreported gene responsible for methyl parathion degradation. Isolates were identified based on 16s rRNA sequence and one highly efficient bacterium selected for genome characterization.
The document discusses biopolymers, which are polymers produced by living organisms. It covers various types of biodegradable polymers including synthetic polymers like polylactic acid (PLA) and natural polymers like starch. The mechanisms of polymer biodegradation are described. Applications of biodegradable polymers in areas like biomedical, packaging and agriculture are also mentioned. Factors affecting the biodegradation of polymers are discussed. Current trends in biopolymers including their use as alternatives to petroleum-based plastics are summarized.
Solubilisation of Quinazoline drugs by using Beta cyclodextrin complex formationRavindra Zirmire
Solubility of the Quinazoline related drugs was enhanced by usind complex formation method,and the Physico chemical characterisation of these drugs was carried out by simplest methods as UV spectroscopy,TLC,FTIR Spectroscopy.
This document summarizes a student's engineering project involving the 1,2-propanediol utilization microcompartment (PDU MCP) in bacteria. The student manipulated the genetic code of bacterial cells to engineer signal sequences on the PDU MCP. Methods included growing bacteria on 1,2-propanediol, using homologous recombination, sequencing, and microscopy. Results showed amplification of the pduD gene to expected sizes. Future applications may include engineering MCPs for use as nanobioreactors in industry by modifying the PduD N-terminus and increasing MCP size and number of localized enzymes.
This document describes a project report submitted by students for their Bachelor of Engineering degree in Biotechnology. The project aimed to optimize the production media components for Sclerotiorin production from Penicillium sclerotorium using a Plackett-Burman experimental design. Sclerotiorin is a metabolite produced by Penicillium sclerotorium that has various biological activities but is currently very expensive due to low production yields. The students analyzed Sclerotiorin production under different media conditions and identified the most important components for high yield production.
Chitin and chitosan source, chemistry, general method of preparation and thei...Hridoy Hridoy
This presentation introduces chitin and chitosan, their sources, chemistry, extraction methods, and applications in the food industry. Chitin is a naturally occurring polysaccharide found in fungi, arthropod exoskeletons, and some other organisms. Chitosan is produced by deacetylating chitin using alkaline substances. Major sources of chitin include crab and shrimp shells. Extraction methods can be chemical, involving demineralization, deprotienization, and decolorization, or biological using lactic acid bacteria. Applications of chitin and chitosan in food include use in edible films, as dietary fiber, antioxidants, preservatives, dye binding, and
The document discusses the production of polyglutamic acid (PGA) by Bacillus subtilis isolates. Key points:
- Sixty-eight B. subtilis isolates were obtained from sugarcane fields, seawater, and marshes water, of which 21 could produce PGA. The highest PGA yields were obtained using isolates SC10 and SW5 in modified media.
- PGA was purified through various steps and identified using tests like ninhydrin, TLC, and spectroscopy. Molecular weights of PGA ranged from 97-131 kDa.
- Hydrogels were formed by treating PGA with gamma rays, alpha rays, beta rays and neutrons, with
Preparation of pyrimido[4,5 b][1,6]naphthyridin-4(1 h)-one derivativeselshimaa eid
This document describes the preparation of pyrimido[4,5-b][1,6]naphthyridin-4(1H)-one derivatives using a zeolite-nanogold catalyst. An efficient one-pot synthesis is developed involving the cyclocondensation of 6-amino-2-thioxo-2,3-dihydropyrimidin-4(1H)-one, aromatic aldehydes, and 1-benzylpiperidin-4-one in ethanol at 80°C. The nanogold catalyst is characterized and found to contain 4-6 nm gold nanoparticles dispersed on zeolite. Several derivatives are synthesized in good yields and characterized. Molecular dock
Induced mutational studies on saccharomyces cerevisiae for bioethanol product...eSAT Publishing House
IJRET : International Journal of Research in Engineering and Technology is an international peer reviewed, online journal published by eSAT Publishing House for the enhancement of research in various disciplines of Engineering and Technology. The aim and scope of the journal is to provide an academic medium and an important reference for the advancement and dissemination of research results that support high-level learning, teaching and research in the fields of Engineering and Technology. We bring together Scientists, Academician, Field Engineers, Scholars and Students of related fields of Engineering and Technology
International Journal of Engineering Research and Applications (IJERA) is an open access online peer reviewed international journal that publishes research and review articles in the fields of Computer Science, Neural Networks, Electrical Engineering, Software Engineering, Information Technology, Mechanical Engineering, Chemical Engineering, Plastic Engineering, Food Technology, Textile Engineering, Nano Technology & science, Power Electronics, Electronics & Communication Engineering, Computational mathematics, Image processing, Civil Engineering, Structural Engineering, Environmental Engineering, VLSI Testing & Low Power VLSI Design etc.
The study identified and characterized a BAHD family acyltransferase in poplar, PtrPHBMT1, that transfers p-hydoxybenzoate from its thio-ester donor to the sinapyl alcohol monolignol. This results in the conjugate being incorporated into nascent lignin polymers, leading to ester-linked p-hydoxybenzoate pendant groups and altering lignin properties. Genetically manipulating this enzyme controlling lignin p-hydroxybenzoylation could allow accumulating this high-value chemical, p-hydoxybenzoate, in lignocellulosic biomass and improve biofuel production and timber dur
This study assessed the enzymatic hydrolysis of proteins from the microalgae Chlorella pyrenoidosa and Spirulina sp. LEB 18 to produce protein hydrolysates. Three commercial proteases were used under different conditions to hydrolyze the microalgae proteins. The highest degrees of hydrolysis for Spirulina and Chlorella, respectively, were 55.31% and 52.9% and were obtained with 4 hours of reaction time using Protemax N200 protease. Statistical analysis showed that enzyme concentration, substrate concentration, and reaction time significantly affected the degree of hydrolysis. The results indicate it is possible to obtain protein hydrolysates with varying degrees of hydrolysis from microalgae
Taiying Zhang is a project scientist at UC Davis studying biomass utilization for biofuels and bioproducts in California. Her research interests include production of biofuels from crops, residue, and algae through economic simulation and life-cycle assessment. She has a Ph.D. in chemical and biochemical engineering from The University of Iowa and was a postdoctoral scholar at UC Riverside studying biological conversion of cellulosic biomass to ethanol. She has authored several referred publications on topics including sugar and chemical production from lignocellulosic biomass.
- Researchers studied the roles of three major prolyl-4-hydroxylase (P4H) isoforms expressed in Arabidopsis roots.
- P4H5 was found to have an essential function different from P4H2 and P4H13, which are partly redundant.
- Protein-protein interaction studies revealed the P4H proteins form homodimers and heterodimers, and P4H5 is necessary for the targeting of P4H2 to the Golgi.
- Understanding the complex regulation and interactions of P4H isoforms impacts root hair expansion and cell wall formation.
1. bioconversion of progesterone using aqueous two phase system by comamonas ...Darshan Rudakiya
Strains of Comamonas acidovoras have been
reported to have vital role in degradation of natural
as well as complex organic compounds.
Comamonas acidovoras MTCC 3364 has been
routinely reported for steroid bioconversion by
activated beads in aqueous system. Previously
studies observed that progesterone was converted
into AD and ADD steroids. These compounds were
higher valuable steroids which were mainly used in
different types of drugs. Novel system was used for
the bioconversion of progesterone in to AD and
ADD. Aqueous two-phase system was initially
optimized for the progesterone solubility, separation
of two phases and extraction of product steroids
from the system. Even 1% of PEG can easily
dissolved progesterone but 5% of PEG needed for
separating phases and for extraction purposes.
Beads was easily tolerate up to 20% of PEG system
even for 120 hours. Hexane used as better
extraction solvent among different type of solvent
system. Products were shown in PEG 6000 system
after 96 hours in fewer amounts. PEG 8000 system
showed products 48 hours in minor amount but
increased in 96 hours. Advantage of aqueous twophase
system in progesterone bioconversion was
better stability of progesterone, extraction of steroid
products and stability of the system.
This document summarizes three papers related to biological conversion of lignocellulosic biomass. The first paper evaluates two red yeast species for their ability to assimilate sugars and aromatics from engineered Arabidopsis plants and successfully converts these products into biofuel precursors. The second paper identifies small drug resistance pumps in Bacillus bacteria that confer tolerance to ionic liquids used in biomass pretreatment and characterizes riboswitches that regulate these pumps. The third paper finds that engineered Pseudomonas putida produces more methyl ketones, a promising diesel blendstock, when grown on plant hydrolysates compared to sugars, due to plant-derived amino acids.
This document summarizes four research articles from the Office of Biological and Environmental Research.
The first article compares pretreatment processes using two ionic liquids to pretreat aspen and maple biomass for biofuel production. It finds one ionic liquid increased crystallinity while the other reduced it.
The second isolates five new Pseudomonas strains from soil that can metabolize pentose sugars, with genomes sequenced. This expands options for converting biomass into fuels and chemicals.
The third engineers poplar trees to produce less lignin using a bacterial enzyme, making the biomass easier to break down into sugars for biofuels. It reduces lignin by up to 30% while incorporating cleavable bonds into the lignin.
This document provides an overview of various polysaccharides including their sources, structures, and applications. It discusses structural polysaccharides like cellulose and pectin, marine polysaccharides such as alginate, microbial polysaccharides including pullulan and cyclodextrins. Cellulose is the most abundant natural polymer derived from plants. Pectin is extracted from citrus and contains galacturonic acid. Alginate is isolated from brown seaweed and forms gels with divalent cations. Chitosan is derived from chitin in insects and crustaceans. Pullulan is produced by Aureobasidium pullulans yeast fermentation. Cyclodextrins are derived from starch and can
IRJET- Solid State Fermentation for Prodigiosin Production using Serratia Mar...IRJET Journal
This document summarizes a study on using food waste as a substrate for solid state fermentation to produce the red pigment prodigiosin using Serratia marcescens bacteria. Various food wastes and inert materials like fibers were tested as substrates. Initial screening found rice husk, palm oil fiber, and sawdust produced the most pigment. Further optimization was done on parameters like incubation time, pH, inoculum size, moisture content, and carbon source to determine the best conditions for maximum prodigiosin production using food waste and rice husk.
This document discusses microbial biotransformation of steroids. It begins with an introduction and definitions of biotransformation. It then covers the history of microbial steroid transformations, advantages of biotransformation, and the phases and requirements of the process. Methods used like oxidation and halogenation are described. Examples of microbial hydroxylation and epoxidation reactions are given. The procedure for carrying out biotransformations is outlined, including using nutritionally rich media, solvent extraction of products, and analytical techniques for structure elucidation. Microbial biotransformations are shown to be useful for producing industrial compounds like steroids and antibiotics.
Isolation and antimicrobial activity of rhamnolipid (biosurfactant) from oil ...eSAT Publishing House
IJRET : International Journal of Research in Engineering and Technology is an international peer reviewed, online journal published by eSAT Publishing House for the enhancement of research in various disciplines of Engineering and Technology. The aim and scope of the journal is to provide an academic medium and an important reference for the advancement and dissemination of research results that support high-level learning, teaching and research in the fields of Engineering and Technology. We bring together Scientists, Academician, Field Engineers, Scholars and Students of related fields of Engineering and Technology
This document examines the process parameters for the biotransformation of benzaldehyde to L-phenylacetylcarbinol (L-PAC) using the yeast Torulaspora delbrueckii. The maximum L-PAC yield of 331 mg/100 ml was obtained with 8 hours of reaction at 30°C using 600 mg of benzaldehyde. Growing the yeast in 3% glucose reduced the reaction time to 120 minutes. Addition of 0.6% acetaldehyde increased the L-PAC yield to 450 mg%. Semi-continuous feeding of benzaldehyde and acetaldehyde produced 683 mg L-PAC/100 ml. The cell mass was reusable for biotransformation up to nine times when substrate concentrations were
Improved Sugar Yield for Bioethanol Production by Modelling Enzymatic Hydroly...theijes
Alternative lignocellulosic substrates to produce high value-added products such as biofuel have been attractive. A Box-Behnken design was used to evaluate the effects of three parameters namely L/S ratio (50_ 100 mL/g), cellulase concentration (10_ 60 U/g) and incubation time (4_ 44h), on the enzymatic hydrolysis yield of physically pretreated Peganum harmala leaves. The fitted mathematical model allowed us to plot response surfaces as well as isoresponse curves and to determine optimal saccharification conditions. Statistical results indicated that the hydrolysis time and the enzyme concentration were the main factors influencing the release of reducing sugars. The selected optimal saccharification conditions were: L/S ratio of 75.0 mL/g, enzyme concentration of 35.0 U/g, and reaction time of 44.0h. These conditions allowed 39.6% of enzymatic hydrolysis yield versus 37.8±2.9%, respectively for the predicted values. The saccharification efficiency using enzyme treated biomass under optimized conditions was about 20-fold higher than before optimization. Fermentation of optimized cellulosic hydrolysate containing 12.6% glucose was performed using Saccharomyces cerevisiae yielded 4.75% ethanol production within 48h. These results showed a promising future of applying Peganum harmala leaves as potential lignocellulosic biomass for second generation bioethanol production.
iaetsd Isolation of cellulose from non conventional source and its chemical m...Iaetsd Iaetsd
This document describes isolating cellulose from the weed plant Prosopis juliflora and chemically modifying it into cellulose acetate. Conditions were optimized for isolating cellulose using sodium hydroxide and sodium chlorite treatments. The best isolation results used 50% sodium chlorite with 20% sodium hydroxide at 90°C for 120 minutes. Conditions for acetylating the cellulose into cellulose acetate were also optimized, with the best results at 100°C for 18 hours. Fourier transform infrared spectroscopy characterized the isolated cellulose and synthesized cellulose acetate.
Chemical and Physical properties of Cassava Starch-Cm-Chitosan-Acrylic Acid Hydrogel prepared from radiation –induced crosslinking
Gatot Trimulyadi Rekso
Center for Application of Isotopes and Radiation- National Nuclear Energy Agency
Jl. Lebak Bulus Raya No. 49, Jakarta-Selatan, Indonesia
Corresponding author; e-mail; gatot2811@yahoo.com ,
Fax: +62-21-.7513270, HP ; 08129419442
This document describes a novel protocol for the construction of 3-spiropyrrolidines and 3-spiropyrrolizidines using Baylis-Hillman adducts derived from nitroolefins via 1,3-dipolar cycloaddition reaction. Specifically, it details the successful synthesis of compound 3, a 3-spiropyrrolidine, from the Baylis-Hillman adduct 2 treated with isatin and N-methyl glycine. The compound was characterized through various analytical techniques and obtained in 62% yield. This reaction demonstrates the utility of Baylis-Hillman adducts from nitroolefins in azomethine ylide-based cycloaddition to form nitrogen-containing
Flor Cabrera's resume summarizes her educational and professional experiences in organic chemistry. She holds a Master's degree in Chemistry from the University of Houston and has worked on organic synthesis projects in Peru, Germany, France, and the United States. Her work has included modifying natural polymers for food preservation, formulating industrial products, synthesizing drug candidates and metal complexes, and implementing analytical techniques like NMR, mass spectrometry, and electrochemistry. Cabrera's portfolio demonstrates her ability to plan and execute multi-step organic syntheses, implement scale-up methods, and solve problems through chemical analysis.
1. BIO-DATA
Name Dr. Soundar Divakar
Department & Fermentation Technology and Bio-Engineering
Institution Central Food Technological Research Institute Mysore- 570013,
India.
E-Mail Address divakar@gmail.com
divakar643@yahoo.co.in
Academic Qualifications and Professional Career:
----------------------------------------------------------------------------------------------------------------
Degree University Period Subject
----------------------------------------------------------------------------------------------------------------
B. Sc. University of Madras 1 971-1974 Chemistry
M.Sc. University of Madras 1974-1976 Chemistry
Ph.D. Australian National 1978-1982 Chemistry
University, Canberra
Research & M/S Reichhold Chemicals 1976-1978 Polymer
Development Ind. Ltd., Madras Chemistry
Chemist
CSIRPool Molecular Biophysics 1983-1987 NMR Studies
Officer Unit, Indian Institute of biomolecules
of Science, Bangalore
Scientist Central Food Technological 1987- NMR studies of
Research Institute biomolecules,
Cyclodextrin
Chemistry and
Lipase catalysis
----------------------------------------------------------------------------------------------------------------
Awards : CFTRI BEST SCIENTIST IN GROUP IV AWARD
FOR THE PERIOD 1998-2004 (Awarded in 2004)
1
2. Fellowships of National Academies: FELLOW-ASSOCIATION OF FOOD SCIENTISTS
AND TECHNOLOGISTS (INDIA) FOR 2002
(Conferred in 2003).
Research Areas
Between October 1976 - August 1978 1 have worked as a Research and Development chemist at Ms.
Reichhold Chemicals (Ind.) Ltd. on the research and development of following polymers.
a) Alkyd resins
b) Unsaturated polyesters
c) Phenol-formaldehyde resins (resoles and novolaks)
d) Urea-formaldehyde resins, and
e) Epoxy resins
NMR Studies of Biological molecules:
I have long been associated with nuclear magnetic resonance spectroscopic investigations of a
large number of biological systems since my PhD work in 1978. During the course of these
investigations multinuclear - 1
H, 13
C, 31
P, 15
N, 27
Al, 23
Na, 39
K,17
O, 19
F, 35
Cl NMR studies of biological
systems investigated include biological molecules with varying degrees of complexities. Conformational
aspects, structure-function correlation and interactions between biomolecules were some of the problems
which were investigated by me. Active site of ribonuclease A was explored with respect to the role of
lysine 41(an active site residue) in the catalytic activity of the enzyme. Detection of polyamines in
belladonna mottle virus and its role in stabilising the virus assembly was investigated by NMR.
Interaction of cupric isonicotinohydrazide (isoniazid) with calf-thymus DNA was studied in relation to
its ability to cleave DNA. Conformation of an antibiotic ionophore A23187 in polar and non-polar
solvents was studied to understand its role in transferring divalent metal ions across the biological
membranes. Structure of curcumin-BF2 complex was explored to stabilise curcumin. Carbon and
phosphorus metabolism, secondary metabolite production, intracellular pH, and permeabilisation of
intact cells by detergents were investigated with reference to intact cell systems of Thermomyces
lanuginosus, Rhodotorula gracilis, Kluyveromyces fragilis and Saccharomyces cerevisiae. Unusual
biphasic melting behaviour of Rhodotorula gracilis DNA was studied by CD and UV measurements.
Crystallinity in natural polysaccharides by solid-state 13C NMR was also investigated. The above
mentioned studies have so far resulted in 16 publications in National and International Journals which
were also citated by other researchers.
2
3. Cyclodextrin Chemistry:
I have been exploring for the last fifteen years (since 1987) various aspects of inclusion
complex formation by ß- cyclodextrin. Structures of several food additive inclusion complexes with ß –
cyclodextrin like aspartame, linoleic and arachidonic acids, substituted phenols, naringin and
cholesterol were investigated by NMR (through one and two dimensional techniques). Orientation of
the above mentioned guest molecules inside ß-cyclodextrin cavity was investigated with respect to the
selectivities exhibited by the inclusion complexes in chemical reactions on the exposed or buried regions
of these guest molecules to produce food additives of commercial importance used in foods. They
include mainly flavour compounds. Enzyme mimicking abilities of ß-cyclodextrin were also explored.
Regio, stereo and chemoselective organic reactions were carried out to prepare menthols from
menthone, thymol and pulegone through hydrogenation and other reduction reactions. Inclusion of
cholesterol inside ß-cyclodextrin cavity was made use of to develop a process to prepare low cholesterol
egg and egg powder. Similar property of ß-cyclodextrin was made use to decaffeinate coffee. Work on
preparation of stereoregular polymers by inclusion polymerisation have also yielded stereoregular
polymers (polyacrylonitrile, polystyrene and poly acyrylonitrile-styrene copolymer) with desired film-
forming properties. ß-Cyclodextrin as a phase-transfer catalyst was investigated in few reactions.
Oxidative potentiality of Cu(II) - ß-cyclodextrin was investigated in few selective oxidative reactions
involving cyclic secondary alcohols like menthol, borneol, isoborneol and cholesterol and other
compounds like eugenol. These investigations have resulted in about 40 publications, 8 Indian Patents
and 1 process. Some of these publications have received good number of citations from other
researchers as well.
Enzyme Catalysed Transformations
Since 1996 lipases and amyloglucosidase catalysed esterification reactions in non-polar solvents
and non-solvent conditions were also investigated by me to produce food additives like flavour and
sufactant esters. Synthetic strategies at both shake flask and large scale levels have been developed.
Several novel methods have been attempted to overcome problems like water activity, microaqueous
pH, alcohol inhibition and hydrolysis. Several basic research aspects of lipase catalysis were
investigated like catalysis by Ping Pong Bi Bi mechanism and enzyme inhibition by the alcohol.
Thermal stability of the lipase in non-polar solvents was investigated. Mathematical modelling of lipase
catalysed reactions by employing extensive Response Surface Methodology and Artifical Neural
3
4. Network studies were carried out. Optimisation studies to achieve maximum conversions using larger
substrate concentrations with lesser enzyme have been carried out to arrive at conditions for large scale
conversions. A novel experimental set-up was arrived at for carrying out lipase mediated reactions at
higher concentration levels. All the estersand glucosides prepared possess food applications. Low
molecular weight bio-degradable poly-esters were also prepared using lipases in non-polar solvents.
These studies have resulted in more than 80 publications and 13 patents so far.
The food additive preparations investigated so far are,
1. Esters of α-terpinol, lactic acid, cresols and anthranilic acid, with low and high molecular weight
organic acids which are used as flavour and fragrance molecules.
2. Bio-degradable polyesters like poly-lactic acids, polycaprolactone. Poly-p-hydroxy benzoate, poly-
p-benzamide and poly adipates.
3. Amino acid esters of sugars – L-alanyl, L-valyl, L-leucyl, L-isoleucyl, L-prolyl, L-phenylalanyl, L-
tryptophanyl and L-histidyl esters of D-glucose, D-galactose, D-mannose, D-arabinose, D-ribose,
maltose, lactose, sucrose, D-mannitol and D-sorbitol.
4. Glycoside preparations Studied: alkyl , n-octyl-, guaiacyl, eugenyl, curcumin, vanillyl, N-
vanillylnonamide, riboflavinyl, thiamine, pyridoxine, retinyl, ergocalciferol, cholecalciferol, α-
tocopherol,L-Dopa, dopamine, serotinonyl, epinephryl glycosides.
Patents and Publications :
Research papers/Books/Reviews/General articles published- 154
Posters - 56
S.N
o.
Year Title of patent
1 1995 AN IMPROVED PROCESS FOR THE PREPARATION OF MENTHONE AND MENTHOLS. -
1357/DEL/95. No.191669/ S.Divakar and R. Ravichandran
2 1997 AN IMPROVED PROCESS FOR THE PREPARATION OF I- PHENETHYL ALCOHOL AND 2-
PHENETHYL ALCOHOL FROM STYRENE OXIDE - 789/DEL/97. No.186805/ S.Divakar and R.
Ravichandran
3 1998 AN IMPROVED PROCESS FOR THE PREPARATION OF STEREOREGULAR POLYMER USING
CLATHRATES - 2149/DEL/98 P. Ravi and S.Divakar
4
5. 4 1998 AN IMPROVED PROCESS FOR THE PREPARATION OFSTERICALLY
CONTROLLED STYRENE-ACRYLONITRILE COPOLYMER USING
CLATHRATES -2380/DEL/98 P.Ravi and S.Divakar
5 1998 A PROCESS FOR THE PREPARATION OF 2-HYDROXY 4-METHOXY
BENZALDEHYDE FROM RESORCINOL 743/DEL/98. No.188336/
S.Divakar, H. H. Pattekhan and Jacob George
6 1998 AN IMPROVED PROCESS FOR THE PREPARATON OF AMYL ESTERS FROM
AMYL ALCOHOL - 2152/DEL/98. No. 189038/1998. S. Harikrishna, S.Divakar,
S.G. Prafulla and N. G. Karanth
7 1998 AN IMPROVED PROCESS FOR THE SIMULTANEOUS PREPARATION OF
MENTHONE AND MENTHOLS FROM THYMOL – 2153/DEL/98.No 190583/
P.Ravi and S.Divakar
8 1998 AN IMPROVED ENZYMATIC PROCESS FOR THE PREPARATION OF FATTY
ACID HYDROXYACIDESTER 1978/DEL/98. 187313/ K.R. Kiran, N.G. Karanth
and S.Divakar
9 1998 AN ENZYMATIC PROCESS FOR THE PREPARATION OF TERPINYL ESTERS
2381/DEL/98 Pramila Rao, N.G.Karanth and S.Divakar
10 1998 AN ENZYMATIC PROCESS FOR THE PREPARATION OF LOW MOLECULAR
WEIGHT ESTERS OF AROMATIC ALCOHOLS. 3696/DEL/98 S.G.
Prafulla,S.Divakar and N. G. Karanth
11 1999 AN IMPROVED PROCESS FOR THE PREPARATION OF ESTERS OF ORGANIC
ACIDS AND ALCOHOLS 1243/DEL/99 No. 191078/ S. Divakar, K.R.Kiran,
S.Harikrishna and N. G. Karanth
12 1999 AN ENZYMATIC PROCESS FOR THE PREPARATION OF PHENOLIC ESTERS
OF ORGANIC ACIDS. 1244/DEL/99. No. 191078/99. N. G. Karanth and
S.Divakar
13 2000 AN IMPROVED ENZYMATIC PROCESS FOR THE PREPARATION OF
POLYLACTIC ACID 257/DEL/00 No.192154/2000. K. R. Kiran, N. G.
Karanth and S.Divakar
14 2001 AN IMPROVED PROCESS FOR THE PREPARATION OF 4-t BUTYLCYCLO
HEXYL ACETATE 422/DEL/01 H. H. PATTEKHAN and S.Divakar
15 2000 AN IMPROVED ENZYMATIC METHOD FOR THE PREPARATION OF 4-t-
BUTYLCYCLOHEXYLACETATE 1205/DEL/00 Pramila Rao andS.Divakar
16 1998 USE OF DECALEPIS HAMILTONII WIGHTAND ARN.(ASCLEPIADACEAE)
ROOT POWDER AND ITS EXTRACTS AS A BIOPESTICIDE AND A
FLAVOURANT-1301/DEL/98 John Periera, Jacob George, G.A. Ravishankar,
Uday Shankar and S.Divakar
17 2000 A PROCESS FOR THE PRODUCTION OF A LIPOXYGENASE INHIBITOR.
301/DEL/00 A.P. Sattur, K.C. Shekar Rao, S.Divakar, A. G. Appu
Rao and N. G. Karanth
18 2000 A PROCESS FOR THE PRODUCTION OF A FERMENTED EXTRACT
CONTAINING A SERINE ESTERASE / PROTEASE INHIBITOR A.P. Sattur,
K.C.Shekar Rao, S.Divakar and N. G. Karanth NF/352/00
19 2001 A PROCESS FOR THE PRODUCTION OF A HUMAN PLATELET
AGGREGATION INHIBITOR 216/DEL/2001 A.P. Sattur, K.C. Shekar Rao,
S.Divakar, N. G. Karanth, J. Suneeta, T. P. Krishnakanth and S. Vishwanath
20 2001 A PROCESS FOR THE PRODUCTION OF AN ACETYLCHOLINESTERASE
INHIBITOR. A.P. Sattur, K.C.Shekar Rao, S.Divakar and N. G. Karanth
219/DEL/2001
5
6. 21 2001 A PROCESS FOR THE PRODUCTION AN PREPARATION OF A NOVEL
ACETYLCHOLINESTERASE INHIBITOR. T. Sivanandappa, A.P.Sattur, Shreen,
S. Divakar and N. G. Karanth .
22 2001 A PROCESS FOR THE PREPARATION OF A BIOACTIVE COMPOUND FROM
THE CULTURES OF ASPERGILLUS NIGER. NF 349/2001. A.P. Sattur,
K.C. Sekhar Rao, S. Divakar, N. G.Karanth , T.R. Shyamala and A.G. Appu Rao.
23 2001 ALDOSE REDUCTASE INHIBITOR AND A PROCESS FOR THE PREPARATION
THEREOF (Appln No. 10/024,574 dt 21st
Dec 2001). A.P. Sattur, K.C. Sekhar Rao,
S. Divakar, K. Naveen Babu, N. G. Karanth and T.R. Shyamala
24 1998 BIOACTIVE COMPOUND AND ITS ISOLATION AND USE FOR
LIPOXYGENASE INHIBITOR AND AS FREE RADICAL SCAVANGING AGENT
PCT/IN/PA-98 A.P. Sattur, K.C. Sekhar Rao, S. Divakar, N. G. Karanth, T.R.
Shyamala and A.G. Appu Rao.
25 2001 A PROCESS FOR THE PRODUCTION OF A HUMAN PLATELET
AGGREGATION INHIBITOR WITH SOYBEAN LIPOXYGENASE INHIBITION
(PCT PATENT) NF 23/2001AP Sattur, KC Sekhar Rao, S Divakar, NG Karanth,
WJ Suneetha, TP Krishnakanth, AG Appu Rao and S Visvanatha
26 2002 BIOACTIVE COMPOUND AND ITS ISOLATION AND METHOD OF
TREATMENT FOR LIPOXYGENASE INHIBITION AND AS FREE RADICAL
SCAVENGING AGENT (APPL. NO. 10/107807 DT 28 MARCH 2002) US
PRODUCT PATENTS AP Sattur, KC Sekhar Rao, S Divakar, NG Karanth, T. R.
Shyamala and A.G. Appu Rao
27 2002 A PROCESS FOR THE EXTRACTION OF AN ANTIOXIDANT PRINCIPLE
FROM POMEGRANATE FRUIT WASTE VIZ. PITH AND CARPELLARY
MEMBRANE. Kulkarni, S. Divakar, S.M. Aradhya. 2002.NF/417/02.
28 2004 AN IMPROVED ENZYMATIC PROCESS FOR THE PREPARATION OF AMINO
ACYL ESTERS OFMONOSACCHARIDES. NF492/03. 498/DEL/2004.
PCT/03/00466. K. Lohith, G.R. Vijaya kumar, B. Manohar and S.Divakar
29 2005 AN ENZYMATIC METHOD FOR THE PREPARATION OFCURCUMIN
GLYCOSIDES. NF – 60/2005, 756/DEL/2005. G.R.Vijayakumar, B. Manohar and
S. Divakar
30 2004 A SINGLE STEP PROCESS FOR THE EXTRACTION OF PLATELET
AGGREGATION INHIBITORY PRINCIPLE FROM INDIAN HOG
PLUM FRUIT (SPONDIAS MANGIFERA WILD). 2004. S.M.Aradhya, M. Siva
Prasad, S. Divakar, T.P. Krishnakantha and W.J. Suneetha.
31 2004 A PROCESS FOR THE EXTRACTION OF ANTIBACTERIAL PRINCIPLE FROM
MANGO GINGER (CURCUMA AMADA ROXB). 2004. S.M. Aradhya,
R.S.Policegoudra and S. Divakar.
32 2004 A PROCESS FOR POLARITY BASED FRACTIONATION CUM EXTRACTION
OF MICROBIAL PIGMENTS. (2004). G. Vijayalakshmi, S. Divakar, N.
Kumaresan and V. Vanajakshi
33 2005 A PROCESS FOR THE DEGRADATION OF NITROPHENOL ISOMERS BY A
SINGLE BACTERIAL CULTURE SARCINA MAXIMA (2005) Shabana basheer,
M. C Varadaraj, A. A. M. Kunhi and S. Divakar NF/301/2005.
PUBLICATIONS
BOOKS PUBLISHED
6
7. 1 2013 ENZYMATIC TRANSFORMATION
SOUNDAR DIVAKAR
Springer, India
2 2014 NAADI ASTROLOGY:PREDICTIVE
RULES. SOUNDAR
DIVAKAR
VL Media Solutions, New Delhi
REVIEWS
1 1994 Applications of β-cyclodextrin i
Organic Syntheses. Maheswaran,
M.M. and Divakar, S.
Journal of Scientific and Industrial
Research, 53, 924-932
2 1998 Nuclear Magnetic Resonance
Spectroscopy in Food Applications - A
Critical Appraisal. Divakar, S.
Journal of Food Science and
Technology, 35(6) 469 - 481 (Impact
Factor = 0.2).
3 2007 A Chapter in a book on Industrial
Enzymes. (2007) J.Polaina and A.P.
MacCabe (Eds)
Springer Publication, 283-300
GENERAL ARTICLES
1 1999 Predicting Disaster Periods. S.Divakar. The Astrological Magazine, 88, 218-
222
2 2007 Can Modern Science Understand
Astrology. S.Divakar.
The Astrological Magazine, 96, 426-
427
3 2009 The Science of Astrology The Astrological Magazine, 21-22,
June.
4 2009 Astrology: A Key to Grand Unification
Vikram Divakar and Soundar Divakar
The Astrological Journal, 51(6), 60.
5 2015 Life on Exo-Planets-An astrological
View
Modern Astrology, 6(11), 430-433
PAPERS
1 1981 NMR studies using paramagnetic
broadening probes in biochemistry.
Bradbury, J.H., Collins, J.G.,
Divakar S., Galloway, G., Foster,
J.R., Hammer, B. and Ramesh.
Bulletin of Magnetic Resonance, 2, 9-
11
2 1984 Interactions of some
sporeconstituents: An NMR
study. Divakar, S.
Indian Journal of Biochemistry
and Biophysics, 21, 166-173(Impact
Factor = 0.6)
3 1985 I
H NMR studies of active site of
ribonuclease A. Divakar, S.
Indian Journal of Biochemistry and
Biophysics, 22, 85-92. (Impact Factor
= 0.6).
7
8. 4 1987 Studies on the interactions of cupric-
isonicotinohydrazide with DNA.
Divakar, S., Vasudevachari, M. B.,
Antony, A. and Easwaran.
Biochemistry, 26, 3781-3785. (Impact
Factor = 3.4).
5 1987 Conformational studies of A23187 with
mono, di and trivalent metal ions by
circular dichroism spectroscopy.
Divakar, S. and Easwaran, K.R.K.
Biophysical Chemistry, 27, 139-147
(Impact Factor = 4.627).
6 1987 Stability of belladonna mottle virus
particles- The chemistry of polyamines
and calcium. Savithri, H.S.,
Suryanarayana, S., Munshi, Divakar, S.
and Murthy, M.R.N.
Journal of General Virology, 68, 1533-
1537. (Impact Factor = 3.1).
7 1987 31
P NMR study of Thermomyces
lanuginosus. Rajasekaran, A.K. and
Divakar,S.
Indian Journal of Biochemistry and
Biophysics, 24, 255-256. (Impact
Factor = 0.6).
8 1988 Carbon-13 NMR spectroscopic
study of a thermophilic fungus
Thermomyces lanuginosus
Rajasekaran, A.K. and Divakar, S.
Current Science, 57(5), 235-237
(Impact Factor = 0.8).
9 1988 A rapid method for monitoring
intracellular lipid production using 1
H
NMR spectroscopy. Sattur, A.P.,
Karanth, N. G. and Divakar, S.
Biotechnology Techniques, 2, 73-76
10 1988 Regulation of phosphate metabolism
during intracellular lipid production in
Rhodotorula gracilis. Sattur, A.P.,
Karanth, N.G. and Divakar, S.
Biotechnology Letters, 10 (10), 745-750.
(Impact Factor = 1.6).
11 1988 Elucidation of the structure of the
compound formed by the reaction
between curcumin and BF3-etherate,
Srinivasa Rao, A., Divakar, S. and
Seshadri, R.
Indian Journal of Chemistry, 27B, 926-
928. (Impact Factor = 0.5).
12 1989 Determination of distances of sugar
protons from Mn2+ in concanavalin A.
Divakar, S.
Indian Journal of Biochemistry and
Biophysics, 26, 190-195. (Impact Factor
= 0.6).
13 1990 Structure of β-cyclodextrin-vanillin
inclusion complex. Divakar, S.
Journal of Agricultural and Food
Chemistry, 38, 940-944. (Impact Factor
= 2.6 ).
8
9. 14 1990 Interaction of
hexadecyltrimethylammonium bromide
with yeast cell S. Divakar.
Indian Journal of Chemistry, 27, 112-117.
(Impact Factor = 0.6).
15 1991 β-Cyclodextrin catalysed
autooxidation of benzoin.
Maheswaran, M.M. and Divakar,S.
Indian Journal of Chemistry, 30A, 181-
183. (Impact Factor = 0.6).
16 1991 Carbon-13 NMR spectroscopic study of
intracellular lipid production in
Rhodotorula gracilis. Sattur, A.P.,
Karanth, N.G. and Divakar, S.
Indian Journal of Chemistry, 30B, 911-
914. (Impact Factor = 0.5).
17 1991 Studies on the structure of the
inclusion compound of β
cyclodextrin with aspartame.
Maheswaran, M.M. and Divakar,S.
Indian Journal of Chemistry,
30A, 30-34. (Impact Factor = 0.6).
18 1991 NMR studies of cyclodextrin
complexes of linoleic acid and
arachidonic acid. Jyothirmayi, N.,
Ramadoss, C.S. and Divakar, S.
Journal of Agricultural and
Food Chemistry, 39, 2123-27. (Impact
Factor = 2.6).
19 1991 Binding of Cu2+- β - cyclodextrin
complex to calf thymus DNA. Divakar,
S., Ramasarma, P.R. and Maheswaran,
M.M.
Indian Journal of Biochemistry
and Biophysics, 28, 247-251. (Impact
Factor = 0.6).
20 1992 Reimer-Tiemann reaction of guaiacol
and catechol in the presence of
cyclodextrin. Divakar, S., Maheswaran,
M.M. and Narayan, M.S.
Indian Journal of Chemistry, 31B, 543-
546. (Impact Factor = 0.5).
21 1993 Spectroscopic studies on the effect
of A13+ on calf thymus DNA.
Jagannatha Rao, K.S. and Divakar,
S.
Bulletin of Environmental
Contamination and Toxicology, 50, 92-
99 ( Impact Factor = ).
.
22 1993 Solid-state carbon-13 NMR study of
some polysaccharides from cereals,
tuber, root and pulses. Vasudeva
Singh, Ali, S.Z. and Divakar, S.
Starch/Starke, 45, 59-62
(Impact Factor = 1.0).
23 1993 Sodium borohydride reduction of
camphor and menthone in
inclusion complexes of β
cyclodextrin. Divakar, S.,
Narayan, M.S. and Shaw, A.K.
Indian Journal of Chemistry, 32B, 387-
389. (Impact Factor = 0.5).
9
10. 24 1993 A structural study on naringin –
cyclodextrin complex. Divakar, S.
Journal of Inclusion Phenomenon and
Molecular Recognition in Chemistry,
15, 305-316. (Impact Factor = 1.1).
25 1993 Selective hydroxymethylation of
guaiacol in the presence of β-
cyclodextrin. Ravichandran, R. and
Divakar, S.
Journal of Inclusion Phenomena and
Molecular Recognition in
Chemistry; 16, 201- 208. (Impact
Factor = 1.1).
26 1994 Disposition of copper (II) in β
cyclodextrin. Divakar, S.
Journal of Inclusion Phenomena and
Molecular Recognition in
Chemistry, 17, 119 – 125. (Impact
Factor = 1.1).
27 1994 Stereoselective reduction of
menthone with sodium dithionite
in the presence of β-cyclodextrin.
Ravichandran, R. and Divakar, S.
Journal of Molecular
Catalysis, 93, L 247-251
(Impact Factor = 2.8).
28 1994 Copper (II)- β-cyclodextrin aided
oxidation of some cyclic secondary
alcohols Divakar, S., Maheswaran,
M. M. and Ravichandran R.
Indian Journal of Chemistry,
33B, 177-178. (Impact Factor = 0.5).
29 1994 β-Cyclodextrin as inverse phase
transfer catalyst in oxidations of
isobomeol, bomeol and menthol by
calcium hypochlorite in aqueous
solution. Ravichandran, R. and
Divakar, S
Journal of Molecular
Catalysis, 88(2), 117-120. (Impact
Factor = 2.8).
30 1994 β-Cyclodextrin and its derivatives
mediated stereoselective reduction
of R-(+)pulegone with sodium
dithionite. Ravichandran, R and
Divakar, S.
Journal of Inclusion
Phenomena and Molecular
Recognition in Chemistry, 18,
369-375. (Impact Factor = 1.1).
31 1995 Unusual biphasic melting
behaviour of Rhodotorula gracilis
DNA. Vishnuvardhan D., Divakar,
S. and Joseph, R.
Biochemical and Biophysical Research
Communications, 211, 978 – 985.
(Impact Factor = 2.6).
32 1995 Studies on Copper-(II)- β
cyclodextrin complex.
Maheswaran, M.M. and Divakar,
S.
Trends in Carbohydrate
Chemistry, P.L.Soni Ed.
Surya Interrnational
Publications, India, 87-95. (Impact
Factor = ).
10
11. 33 1995 β-Cyclodextrin mediated synthesis
of stereoregularity in
polyacrylonitrile polymers. Ravi,
P. and Divakar, S.
Journal of Macromolecular
Science- Pure and Applied
Chemistry, A32 (5), 1061-1066. (Impact
Factor = .0.709)
34 1995 Influence of embedded phenol
groups inside β-cyclodextrin cavity
in selective methylation of 2,4
dihydroxybenzaldehyde. George, J
and Divakar, S.
Indian Journal of Chemistry,
34B, 1098-1101. (Impact Factor = 0.7).
35 1996 Enhancement of oxidation of some
cyclic secondary alcohols by
copper-β-cyclodextrin in
pyridineacetic acid – hydrogen
peroxide system. R. Ravichandran
and S.Divakar.
Indian Journal of Chemistry,
35B, 264-266. (Impact Factor = 0.5).
36 1996 Hydrolysis of DL-tryptophan
isopropyl ester catalysed by β
cyclodextrin. R. Ravichandran and
S.Divakar.
Indian Journal of Chemistry,
Sec.A, 35A, 504-507. (Impact Factor =
0.6).
37 1996 β-Cyclodextrin and its derivatives
directed axial attack by hydride ion
in the reduction of R- (+)-Pulegone
and (2S, 5R)-(-)-menthone. R.
Ravichandran and S.Divakar.
Journal of Molecular Catalysis
A, 109, 201 – 208. (Impact Factor =
2.8).
38 1996 Reduction of trans-cinnamaldehyde
over Raney Nickel mediated by
derivatives of β-cyclodextrin.
Ravichandran, R. and Divakar, S.
Indian Journal of Chemistry,
35B, 1167-1173. (Impact Factor = 0.5).
39 1997 Structural studies on Inclusion
compounds of β-cyclodextrin with
some ortho substituted phenols.
Maheswaran, M. M. and Divakar,S.
Journal of Inclusion
Phenomena and Molecular
Recognition in Chemistry, 27,
113-126. (Impact Factor = 1.1).
40 1997 Influence of β-cyclodextrin in bio-
transfomation of (+)-3-carene by cell
suspension cultures of Acetobacter acetii.
Pattekhan, M. C. Varadaraj, N. Keshava
and S.Divakar.
Biotechnology Techniques,
11(6), 379-383. (Impact Factor = ).
41 1998 Inclusion of ring A of cholesterol inside
β-cyclodextrin cavity-Evidence from
Oxidation Reactions and Structural
Studies. Ravichandran and S.Divakar.
Journal of Inclusion Phenomena and
Molecular Recognition in Chemistry,
30, 253-270. (Impact Factor = 1.1).
11
12. 42 1998 Response surface studies on cholesterol
reduction in egg-yolk using β-
cyclodextrin. Manohar, B., Channa
Basappa, D. Narasimha Rao and
S.Divakar.
Zeitschrift Lebensmittel Untersuchung
and Forschung, 206,189-192. (Impact
Factor = 1.6).
43 1998 A modified calorimetric method for
the estimation of β-cyclodextrin
using phenolphthalein. Channa
Basappa, Pramila Rao,
D.Narasimha Rao and S.Divakar.
International Journal of
Food Science and Technology
33, 1998, 517-520. (Impact
Factor = 1.1)
44 1999 Preparation of stearoyl lactic acid ester
catalysed by lipases from Rhizopus
Mucor meihei and Porcine pancreas-
Optimization using responce surface
methodology Kiran, K.R., N.G.Karanth
and S.Divakar.
Appl. Microbiol. BioTech. 52, 1999,
579-584. (Impact Factor = 2.6)
45 1999 Optimisation of growth parameters
for the production of carotenoids
by Rhodotorula gracilis.
G.Vijayalaksmi, V. Vanajakshi and
S.Divakar.
Zelt.Leb. Unt. Fors, 208(2),
1999, 121-124. (Impact Factor
= 1.6)
46 1999 Bioinsecticide from Swallow Root
(Decalepis hamiltonii Wight & Am)
protects food grains against insect
infestation. Jacob George, G.A.
Ravishankar, J. Pereira and
S.Divakar.
Current Sci, 77(4), 1999, 501-502.
(Impact Factor = 0.8)
47 1999 Regulatory nature of β-cyclodextrin
in selective ring opening during
reduction of styreneoxide.
Ravichandran, R. and Divakar, S.
J.Mol. Catal.A. Chemical 137,
1999, 31-39. (Impact Factor =
2.8)
48 1999 Digestion of residual β-cyclodextrin
in treated egg using glucoamylose
from a mutant strain of Aspergillus
niger (CFTRI 1105). Pramila Rao..C.
Suresh, D. Narasimha Rao,
S.Umesh Kumar and S.Divakar,
Food Chemistry, 65, 1999, 297
302. (Impact Factor = 2.7)
12
13. 49 1999 Stereoselective hydrogenation of R
(+)-pulegone and (-)- 2S, 5R-
menthone in presence of β
cyclodextrin and its derivatives,
Ravi, P.Ravichandran, R. And
Divakar, S.
J. Mol.Catal. 148, 1999, 145-155.
(Impact Factor = 2.8)
50 1999 β-Cyclodextrin regulated
Stereoregularity and Molecular
weight in inclusion polymerization
of acrylonitrile, Ravi, P. and
Divakar, S
J. Macromol. Sci., Pure and
Applied Chemistry,
36(12),1999,1935-1948. (ImpactFactor
= 0.7)
51 1999 Lipase catalysed synthesis of
isoamyl butyrate: Optimization by
Response Surface Methodology. S.
Harikrishna, B. Manohar, S.
Divakar and N. G. Karanth
J. Am. Oil Chem. Soc.
76,1999,1483–1488.
(Impact Factor = 1.0).
52 2000 Optimisation of digestion
parameters for the elimination of
residual β-cyclodextrin used for
cholesterol reduction in egg using
glucoamylase. Pramila Rao, Umesh
Kumar, S. Narashima Rao, D and
Divakar, S.
Z. Lebm. Unt. Fors, 210, 2000,
231 - 236. (Impact Factor =
1.6)
54 2000 β-Cyclodextrin mediated synthesis
of Syndiotactic rich Polystyrene. P.
Ravi K. Udaya Shankar and
S.Divakar.
J. Incln Phenom and
Macrocyclic Chemistry 38,
2000, 99-112(Impact Factor =
1.1)
55 2000Sa Safety aspects of residual β-
Ccycyclodextrin in egg treated for
cholesterol removal. Pramila Rao,
Sujatha, K.Vishwanatha, Rathinraj, K
Narasimha Murthy, P. Sai Baba, D.
Narasimha Rao and S.Divakar.
Z. Z. lebm. Unt. Fors. 211, 2000,393
395. (Impact Factor = 1.6)
56 2000 β-Cyclodextrin mediated synthesis of
sterically controlled styrene-
acrylonitrile co-polymer. P. Ravi and
S.Divakar
J. Inclusion Phenom and Macrocyclic
Chemistry. 38, 2000. 323-336, (Impact
Factor = 1.1)
13
14. 57 2000 Optimisation of isoamyl acetate
production using immobillsed lipase
from Mucor miehei by Response Surface
Methodology S. Harikrishna, B.
Manohar, S.Divakar, S. G. Prafulla and
N. G. Karanth. .
Enz. Microb. Tech. 26, 2000, 131- 136.
(Impact Factor = 2.4)
58 2000 Response Surface Methodological study
of esterification of lactic acid with
palmitic acid catalysed by immobilisqd
lipases from Mucor miehei and porcine
pancreas. Kiran, K. R., Manohar, B.,
Karanth, N. G. and Divakar, S.
Z. Lebm. Unt. Fors. 211, 2000,130-135.
(Impact Factor = 1.6)
59 2000 An esterification method for
determination of lipase activity.
Kiran, K. R., Harikrishna, H. Suresh
Babu, C. V., Karanth, N. G. And
Divakar, S.
Biotechnology Letters, 22(19),
2000, 1511 -1514. (Impact
Factor =1.6)
60 2001 Stereoselective Hydrogenation of
Thymol Over Rh/Alumina in the
Presence of Cyclodextrin and its
derivatives. P. Ravi and S.Divakar.
J. Incln Phenom., 2001, 39, 27-32.
(Impact Factor =1.1)
61 2001 Selection of alcohols through
Plakett-Burman design in lipase
catalyzed syntheses of anthranilic
acid. C.V. Suresh Babu and
S.Divakar,
J. Am. Oil Chem. Soc., 78(1),
2001, 49 – 52. (Impact Factor =
1.0)
62 2001 Enzymatic synthesis of isoamyl acetate
using immobilised lipase from
Rhizomucor meihei. S. Harikrishna,
S.Divakar, S.G. Prapulla and N.G.
Karanth,
J. Biotechnology, 87(3), 2001, 193-201.
(Impact Factor = 2.7)
63 2001 Lipase catalysed esterification of α -
terpineol with various organic acids
Application of the Plakett- Burman
design. Pramila Rao and S.Divakar,
Process Biochemistry, 36,
2001,1125 - 1128. Impact Factor – 2.4
64 2001 Lipase catalysed synthesis of
organic ester of lactic acid in non
aqueous media. K. R. Kiran and S.
Divakar.
J. Biotechnology., 87, 2001, 109
121. (Impact Factor = 2.7)
14
15. 65 2001 Thermostability of porcine pancreas
lipase in non - aqueous media.
Kiran, K. R., Suresh Babu, C. V. And
Divakar, S.
Process Biochemistry, 36, 2001, 885 –
892. Impact Factor – 2.4
66 2001 Response surface methodological
approach for the synthesis of isobutyl
butyrate. D.R. Hamsaveni, S. G.
Prapulla, and S. Divakar.
Process Biochemistry, 36(11), 2001,
1103 – 1109. (Impact Factor – 2.4)
67 2001 A central composite rotatable
design analysis of lipase catalysed
synthesis of lauroyl lactic acid at
bench-scale level. Kiran, K. R.,
Manohar, B. and Divakar, S.
Enz. Microbial Technology,
29, 2001, 122-128. (Impact
Factor = 2.4)
68 2001 Response surface methodology for
optimisation of growth parameters for
the production of carotenoids by a
mutant strain of Rhodotorula gracilis. G.
Vijayalakshmi, B. Shobha, V.
Vanajakshi, S.Divakar and B. Manohar.
Z. Lebs. Unt. Fors. 213, 2001, 234-239.
(Impact Factor = 1.6)
69 2001 New metabolic pathway for o-cresol
degradation by Pseudomonas CP4 as
evidenced by 'H NMR spectroscopic
studies. P. Y. Aneez Ahamad, A. A. M.
Kunhi and S. Divakar.
World J Microbiol. Biotechnol, 17,
2001, 371-377. (Impact Factor = 0.9)
70 2001 Physico-Chemical properties of
polystyrene prepared by inclusion
polymerisation. P.Ravi, S.Divakar,
Siddaramaiah and R. Somashekar.
J. Polymer Materials, 19, 2001,
127-134. (Impact Factor =
0.3)
71 2001 Regioselectivity in the preparation of2-
hydroxy-4-ethoxybenzaldehyde from
resorcenol in presence of β- cyclodextrin
and its derivatives. H. H. Pattekhan and
S.Divakar.
J. Mol. Catal A:Chemical, 169,
2001, 185-191. (Impact Factor =
2.8)
72 2001 14-(2’,3’,5’-trihydroxyphenyl)
tetradecane-2-ol, A novel
acetylcholinesterase inhibitor from
Chrysosporium sp. K.C. Sekhar Rao,
S. Divakar, N. G. Karanth and A.P.
Sattur.
The Journal of Antibiotics.
54(10), 2001, 848-849. (Impact
Factor = 1.3)
15
16. 73 2001 Scanning electron microscopic
studies of lipase catalysed
esterification catalysis for te
synthesis of steroyl lactate and p
cresyl lactate. Suresh Babu, C. V.,
Kiran, K, R. and Divakar, S.
World J. Micro. Biotech. 17,
2001, 659 – 665. (Impact Factor
= 0.9)
74 2002 Regioselective acetylation of 4-t
butylcyclohexanol in the presence of
β-cyclodextrin and its derivatives H.
H. Pattekhan and S.Divakar.
J. Mol. Catal A:Chemical, 184,
2002, 79-83. (Impact Factor =
2.8)
75 2002 A lipoxygenase inhibitor from
Aspergillus niger. K.C. Sekhar Rao, S.
Divakar, A. G. Appu Rao, N. G.
Karanth and A.P. Sattur.
Appl. Microbiol. Biotech. 58,
2002, 539-542. (Impact Factor
= 2.6)
76 2002MModelling on isoamyl isovalerate
synthesis from Rhizomucor miehei lipase
in organic media: Optimisation studies.
Chowdary, G.V., Divakar, S. And
Prapulla, S. G.
World Journal of Microbiology
and Biotechnology, 18, 2002,
179-185. (Impact Factor =
0.9)
77 2002 Response surface methodological
approach for Rhizomucor miehei
lipase-mediated esterification of α-
terpineol with propionic acid and
acetic anhydride. Pramila Rao and
Divakar, S.
World Journal of Microbiology
and Biotechnology, 18, 2002,
341 - 345. (Impact Factor =
0.9)
78 2002 Lipase catalysed esterification of
free hydroxyl groups β-cyclodextrin
and its derivatives. H. H.
Pattekhan and S.Divakar.
Indian Journal of Chemistry,
41B, 1025-1027. (Impact Factor = 0.5).
79 2002 Lipase catalysed esterification of cresols.
Suresh Babu, C. V., Karanth, N. G. and
S. Divakar,
Indian Journal of Chemistry,
41B, 1068-1071. (Impact Factor = 0.5).
80 2002 NMR and HPLC characterisation of O –
alkanoyl lactates prepared by lipase
catalysis. K. R. Kiran and S. Divakar.
Indian Journal of Chemistry,
41B, 1686 – 1693. (Impact Factor =
0.5).
81 2002 Preparation of O-palmitoyl alkyl
lactates through lipase catalysis. K. R.
Kiran and S. Divakar
World Journal of Microbiology
and Biotechnology, 18(2), 121
124. (Impact Factor =
0.9)
16
17. 82 2002 Hydrogen ions in microaqueous phase
during lipase catalysed esterification in
non-aqueous media. K. R. Kiran, N.G.
Karanth and S.Divakar.
Indian Journal of Biochemistry and
Biophysics, 39, 101 – 105. (Impact
Factor = 0.6).
83 2002 Lipoxygenase inhibitor from
Lactobacillus casei. . K.C. Sekhar Rao,
S. Divakar, A. G. Appu Rao, N. G.
Karanth and A.P. Sattur.
Biotechnology Letters, 24(7),
511-513. (Impact Factor = 1.6).
84 2002 Plakett-Burman design for determining
the preference of Rhizomucor miehei
lipase for fatty acid in acidolysis
reactions with coconut oil. Reena Rao,
S. Divakar and B. R. Lokesh.
Journal of American Oil
Chemists’ Society, 79, 555 –
560. (Impact Factor = 1.0).
85 2002 Enzyme inhibition by p-cresol and lactic
acid in lipase mediated syntheses of p--
cresyl acetate and stearoyl lactic acid: A
kinetic study. Kiran, K. R. and Divakar,
S..
World Journal of Microbiology
and Biotechnology, 18, 707 –
712. (Impact Factor =
0.9)
86 2002 Structure - Function correlation in lipase
catalysed esterification reactions of
short and medium carbon chain length
alcohols and acids. S. Divakar.
Indian Journal of Chemistry,
Section B, 41B, 1919 – 1922. (Impact
Factor = 0.5).
87 2002 Application of central composite
rotatable design to lipase catalyzed
syntheses of m-cresyl acetate. Manohar,
B. and Divakar, S.
World Journal of Microbiology
and Biotechnology, 18(8), 745
751. (Impact Factor =
0.9)
88 2002 Asperenone – An inhibition of 15-
lipoxygenase and of human platelet
aggregation from Aspergillus niger. K.C.
Sekhar Rao, S. Divakar, A. G. Appu
Rao, N. G. Karanth, W.J. Suneetha, T.P.
Krishna Kantha and A.P. Sattur.
Biotechnology Letters, 24,
1967-1970. (Impact Factor = 1.6).
89 2002 Nigerloxin - A novel inhibitor of Aldose
reductase and lipoxygenase from
Aspergillus niger CFR W-105 K.C. Sekhar
Rao, S. Divakar, K. Naveen Babu, A.G.
Appu Rao, N. G. Karanth and A.P.
Sattur.
Journal of Antibiotics, 55 (9),
789-793. (Impact Factor = 1.3).
17
18. 90 2003 Sodium dithionite reduction of
2S,5R-(-)-menthone and R-(+)
pulegone in the presence of β–
cyclodextrin and hydroxypropyl-β
cyclodextrin. P. Ravi and S.
Divakar.
Journal of Inclusion
Phenomena and Macrocyclic
Chemistry, 45, 2003, 191-194. (Impact
Factor = 1.1).
91 2003 Copper (II)-β–cyclodextrin aided
oxidation of eugenol. H.H.
Pattekhan and S. Divakar.
Indian Journal of Chemistry,
42B, 2003, 369-371. (Impact Factor =
0.5).
92 2003 Lipase catalysed regioselective
esterification of protocatechuic
aldehyde. S. Divakar,
Indian Journal of Chemistry,
Section B, 42B, 1119-1122. (Impact
Factor = 0.5).
93 2003 Porcine pancreas lipase catalysed
preparation of oligomers of p-
hydroxybenzoic acid and p-
aminobenzoic acid. S. Divakar.
Indian Journal of Chemistry,
Section B, 42B, 1467–1470. (Impact
Factor = 0.5).
94 2003 Asperaldin - A new aldose reductase
inhibitor from Aspergillus niger CFR
1046. K.C. Shekar Rao, S. Divakar, K.
Naveen Babu, N.G.Karanth and A.P.
Sattur. .
The Journal of Antibiotics, 56,
173 – 176. (Impact Factor = 1.3).
95 2003 Lipase catalysed polymerisation of
lactic acid. K.R. Kiran and S. Divakar.
World Journal of Microbiology
and Biotechnology, 19, 859-865 .
(Impact Factor =0.9)
96 2004 Application of surface plots and
statistical designs to selected lipase
catalysed esterification reactions. B.
Manohar and S. Divakar,.
Process Biochemistry, 39 (7), 2004, 847
– 851. (Impact Factor = 2.4).
97 2004 Porcine pancreas lipase catalysed ring-
opening polymerisation of ε -
caprolactone. S. Divakar,
Journal of Macromolecular Science A –
Pure and Applied Chemistry, A41(5),
2004, 537-546. (Impact Factor = 0.7).
98 2004 Isolation and identification of a radical
scavenging antioxidant – punicalagin
from pith and carpellary membrane of
pomegranate fruit (Punica granatum).
Kulkarni, A.P., Aradhya, S.M. and
Divakar, S.
Food Chemistry, 87, 551-557. (Impact
Factor = 2.7).
18
19. 99 2004 Lipase catalysed synthesis of L-alanyl,
L-Leucyl and L-phenylalanyl esters of
D-glucose using unprotected amino
acids. G.R. Vijayakumar, K. Lohith, B.R.
Somashekar and S. Divakar.
Biotechnol. Letters 26, 2004, 1323-1328.
(Impact Factor = 1.6).
100 2004 Porcine pancreas lipase catalysed
acetylation of β–cyclodextrin anchored
4-t-butylcyclohexanol. B. Manohar and
S. Divakar.
Indian Journal of Chemistry,
Section B, 43B, 2004, 2661-2665.
(Impact Factor = 0.5).
101 2005 Amyloglucosidase catalyzed synthesis
of n-octyl–D-glucoside – Analysis using
response surface methodology. G.R.
Vijayakumar, B. Manohar and S.
Divakar.
European Food Research and
Technology, 220, 2005, 272-277.
(Impact Factor = 1.6).
102 2005 Isolation of a free radical scavenging
antioxidant from water spinach (Ipomea
aquatica Forsk). Nagendra Prasad, S.
Divakar, G.R. Shivamurthy and S.M.
Aradhya,
Journal of the Science of Food
and Agriculture, 85, 1461-1468.
(Impact Factor = 1.3).
103 2005 Lipase catalysed synthesis of L-
phenylalanine-D-glucose. K. Lohith and
S. Divakar.
Journal of Biotechnology, 117, 2005,
49-56. (Impact Factor = 2.7).
104 2005 An artificial neural network analysis of
porcine pancreas lipase catalyzed
esterification of anthralic acid with
methanol. B. Manohar and S. Divakar.
Process Biochemistry, 40, 2005, 3372-
3376. Impact Factor – 2.4
105 2005 Synthesis of guaiacol-α-glucoside and
curcumin-bis-α-D-glucoside by an
amyloglucosidase from Rhizopus. G.R.
Vijayakumar and S. Divakar..
Biotechnology Letters,
27(18),2005, 1411-1415. (Impact Factor
= 1.6).
106 2005 Isolation of antioxidant compounds
from the methanolic extract of the roots
of Decalepis hamiltonii. (Wight and Ani.)
R. Harish, S. Divakar, Anoop Srivastava
and T. Shivanandappa.
Journal of Agricultural and
Food Chemistry, 53(20), 7709
7714. (Impact Factor = 2.6).
107 2006 Glycosylation of vanillin by
amyloglucosidase in organic media. R.
Sivakumar and S. Divakar.
Tetrahedron Letters. 47, 2006, 695-699.
(Impact Factor = 2.5).
19
20. 108 2006 Amyloglucosidase catalysed synthesis
of curcumin-bis-α-glucoside – A
response surface methodological study.
G.R.Vijayakumar, B.Manohar and S.
Divakar.
European Food Research and
Technology. 223, 2006, 725-730.
(Impact Factor = 1.6).
109 2006 Angiotensin Converting Enzyme
inhibitory activity of amino acid esters
of carbohydrates. Vasudeva Kamath,,
Rajini P.S, Lohith K, Somashekar B.R
and Divakar S.
International Journal of Biological
Macromolecules. 38, 2006, 89-93.
(Impact Factor = 1.9).
110 2006 Competitive substrate inhibition of
amyloglucosidase from Rhizopus sp. by
vanillin and curcumin. R. Sivakumar,
G.R. Vijayakumar, B. Manohar and S.
Divakar
Biocatalysis and Biotransformations,
24, 2006, 299-305. (Impact Factor =
1.2).
111 2006 Influence of buffer and L-phenylalanine
concentration in the Rhizomucor miehei
lipase catalysed synthesis of L-
phenylalanyl-D-glucose ester
investigated through response surface
methodology. K. Lohith, B. Manohar
and S. Divakar.
European Food Research and
Technology. 224(2), 2006, 219-224.
(Impact Factor = 1.6).
112 2006 Glycosides and amino acyl esters of
carbohydrates as potent inhibitors of
Angiotensin Converting Enzyme. K.
Lohith, G. R. Vijayakumar, B. R.
Somashekar, R. Sivakumar, S.Divakar
European Journal of Medicinal
Chemistry 41, 2006, 1059-1072.
(Impact Factor = 2.9).
113 2007 Lipase catalyzed synthesis of L-a
lanyl esters of carbohydrates. B. R.
Somashekar and S. Divakar.
Enzyme and Microbial
Technology, 40, 2006, 299-309. (Impact
Factor = 2.4).
114 2007 Nuclear magnetic resonance
spectroscopic studies on the microbial
degradation of mononitrophenol
isomers. Shabana basheer, A. A. M.
Kunhi, M. C. Varadaraj and S. Divakar.
World Journal of Microbiology
and Biotechnology, 23(1), 49-63 .
(Impact Factor = 0.9)
115 2007 Isolation and characterization of
dihydromonacolin-MV from Monascus
purpureus for antioxidant properties.
Mohan A. Dhale, S. Divakar, S. Umesh
Kumar, and G.Vijayalakshmi.
Journal of
AppliedMicrobiology and
Biotechnology, 73, 1197
1202. (Impact Factor = 2.0).
20
21. 116 2007 Synthesis of n-alkyl glucosides by
amyloglucosidase. G.R. Vijayakumar,
Charles George and S. Divakar.
Indian Journal of Chemistry.
46B, 2007, 314-319. (Impact
factor-0.5)
117 2007 Identification of difurocumenonal, a
new antimicrobial compound from
mango ginger Curcuma amada. R.S.
Police Gowda, S. Divakar and S.M.
Aradhya.
Journal of Applied
Microbiology.102, 2007, 1594
1602. Impact Factor-2.0.
118 2007 Inhibition of Rhizomucor miehei and
Candida rugosa lipases by D-glucose in
esterification between L-alanine and D-
glucose. B.R. Somashekar, K. Lohith, B.
Manohar and S. Divakar.
Journal of Bioscience and
Bioengineering, 103(2), 2007, 122-128.
Impact factor- 1.7
119 2007 Competitive inhibition by substrates
of the esterification reaction
between L-phenylalaninine and D
glucose catalysed by the lipases of
Rhizomucor miehei and Candida
rugosa. K. Lohith, B. Manohar and S.
Divakar.
World Journal of Microbiology
and Biotechnology, 23,2007,
955-964. Impact factor-0.9
120 2007 Candida rugosa lipase catalysed
preparation of L-prolyl, L
phenylalanyl, L-tryptophanyl and
L-histidyl esters of carbohydrates.
K.Lohith and S. Divakar 2006.
Biochemical Engineering
Journal. 34, 2007, 28-43. (Impact Factor
= 1.9).
121 2007 Synthesis of vanillyl-maltoside
using glucosidases by response
surface methodology. R. Sivakumar,
B. Manohar and S. Divakar.
European Journal of Food
Research and Technology,
226, 2007, 255-263. Impact
factor- 1.6
122 2007 Amyloglucosidase catalyzed
synthesis of eugenyl and
curcuminyl glycosides
G.R.Vijayakumar and S. Divakar..
Biotechnology Letters, 29,2007,
575-584. Impact factor-1.6
123 2007 Isolation and characterization of
dihydromonacolin-MV2 from
Monascus purpureus for antioxidant
properties. Mohan A. Dhale, S.
Divakar, S. Umesh Kumar, and
G.Vijayalakshmi.
Journal of Applied
Microbiology, 102 (6), 1194
1203. (Impact Factor = 2.0).
21
22. 124 2007 Synthesis of N-vanillyl-nonanamide
glycosides using amyloglucosidase
glucosidase for Rhizopus and β
glucosidase from sweet almond. R.
Sivakumar and S. Divakar.
Biotechnology Letters, 29,
2007, 1537-1548. Impact factor
1.6
125 2007 Enzymatic synthesis of L-valyl, L
leucyl and L-isoleucyl esters of
carbohydratesusing Candida rugosa
lipase . B.R. Somashekar and S.
Divakar.
Indian Journal of Chemistry,
section B, 46B, 2007, 2026-2044.
Impact factor-0.5
126 2008 Synthesis of α-tocopherl glycosides
T. Ponrasu, R.E. Charles, R.
Sivakumar and S.Divakar.
Biotechnology Letters, 2008,
30, 1431-1439 Impact factor
1.6
127 2008 Possibledegradation/biotransformat
on of lutein in vitro and in vivo –
Isolation and structural elucidation
Of lutein metabolites by HPLC and
LC MS (APCI). R. aksminarayana, G.
Aruna, R.K. Sangeetha, N. Bhaskar,
S.Divakar and V. Baskaran
Free Radicals in Biology and
Medicine. 2008,45, 982-993.
Impact Factor – 4.813
128 2009 Angiotensin converting enzyme
inhibitory and antioxidant activities of
enzymatically synthesized phenolic and
vitamin glycosides R.E. Charles , T.
Ponrasu, R. Sivakumar and S.Divakar
BIOTECHNOLOGY AND
APPLIED BIOCHEMISTRY.
2009, 52, 177-184., (Impact Factor –
1.269 )
129 2009 Syntheses of dopa glycosides using
glucosidases. R. Sivakumar,
T.Ponrasu and S. Divakar.
Glycoconjugate Journal. 2009, 26, 199-
209.
Impact Factor – 1.7
130 2009 Enzymatic syntheses of dopamine
glycosides. R. Sivakumar and S.Divakar
Enzyme and Microbial Technology,
2009, 44, 33-49. Impact Factor – 2.4
131 2009 β-glucosidase catalysed syntheses of
Pyridoxine glycosides. R.E. Charles and
S.Divakar
Bioscience, Biotechnology and
Biochemistry 2009, 73, 233-236.
Impact Factor – 1.247
132 2009 A response surface Methodological
study on prediction of glucosylation
yields of thiamin using immobilized
β-glucosidase T. Ponrasu , B.
Manohar and S.Divakar
Process Biochemistry, 2009, 44, 251-
255 . Impact Factor – 2.4
22
23. 133 2009 Syntheses of retinol glycosides using β-
glucosidase in SCCO2 media. R.E.
Charles , T. Ponrasu, K. dayashankar
and S.Divakar
APPLIED BIOCHEMISTRY AND
BIOTECHNOLOGY. 2009, 159,
199-207. Impact Factor - 1.643
134 2009 Amyloglucosidase catalyzed syntheses
of Bakuchiol glycosides in SCCO2. B.
Manohar , S.Divakar, K. Udaya
Sankar
Bulletin of Korean Chemical Society.
2009, 30, 1760-
1766. Impact Factor - 1.043
135 2009 Amyloglucosidase from Rhizopus
mold and β-glucosidase from sweet
almond catalyzed synthesis of
riboflavinyl glycosides R. Sivakumar
and S.Divakar
Indian Journal of Biotechnology. 2009,
8, 400-407. (Impact Factor = ).
136 2010 Bioavailability and metabolismof
fucoxanthin in rats: structural
characterization of metabolites by LC-MS
(APCI). R.K. Sangeetha, N. Bhaskar, S.
Divakar and V. Baskaran.
Molecular and Cellular Biochemistry.
2010, 333, 299-310
Impact Factor - 1.643
137 2009 Evaluation of phophoglyco lipid
elimination from rice bran oil by a non-
porus membrane using NMR
spectroscopy
Manjula S, Divakar S, Subramanian R
European Journal of Food Science and
Technology , 111 (10),1020-1026 Oct
2009. (Impact Factor = ).
138 2010 Enzymatic synthesis of Cholecalciferol
glycosides. B. Manohar and S.Divakar
Journal of Food Science and Technology,
2010, 46(5), 469-475 Impact Factor - 0.2
139 2010 Chemical composition of Nigella
sativaL. Seed extracts obtained by
SCCO2, TV Suresh Kumar, HH
Pattekhan, K.Udayasankar and S.
Divakar
Journal of Food Science and
Technology, 2010, Volume 47 (6),
p.598. (Impact Factor = 0.2).
140 2010 Degumming rice bran oil by
phospholipase A1, Manjula S, Divakar
S, Subramanian R
European Journal of Lipid Science and
Technlogy, 2010, 113, 658-664.
(Impact Factor = ).
141 2011 Enzymatic Synthesis of serotonyl and
epinephryl glycosides, G.Vadivelan
and S. Divakar
International Journal of Fundamental
and Applied Life Sciences, 2011,
Vol 1(2), 15-21. (Impact Factor = ).
23
24. 142 2011 Enzymatic synthesis of L-Dopa
glycosides G. Vadivelan and Divakar S
Indian Journal of Chemistry, Section
B, 50B, 1779-1785,2011. (Impact
Factor = ).
143 2012 Prediction Of Yields In Glucosylation Of
Ergocalciferol Through Response
Surface Methodology and Artificial
Neural Network Analysis
International Journal of Fundamental
and Applied Life Sciences,2(4), 40-
50
144 2013 Enzymatic Synthesis of thymol
glycosides, TV Suresh Kumar,
K.Udayasankar and S. Divakar
Journal of Food Science and Technology,
50(4), 803-808. (Impact Factor =
).
Papers Presented in Seminars and Symposia : 56
Member
Association of Food Scientists and Technologists India
Society of Biological Chemists India
Nuclear Magnetic Resonance Society of India
Other Activities:
1. Recognized as a guide for students towards award of M. Phil and Ph.D degree in Chemistry,
Biochemistry and Biotechnology in University of Mysore.
2. Recognized as a referee for Indian Journal of Chemistry, Section B, Process Biochemistry, Journal
of Agriculture and Food Chemistry and Biotechnology Progress.
Information on Ph.D Students:
a) Number of students awarded Ph.D degree: Ten
Title: 1. Studies on inclusion complexes of β-cyclodextrin – M.M.Maheswaran
2. Studies on application of β-cyclodextrin and its derivatives in organic synthesis – R.
Ravichandran
3. Studies on steric control in some β-cyclodextrin mediated organic reactions – P.
Ravi
4. Studies on transformations mediated by β--cyclodextrin and its derivatives for the
production of food additives – H.H.Pattekhan
24
25. 5. Studies on lipase catalysed esterification of lactic acid – K.R. Kiran
6. Studies on bio-degradation of nitrophenol isomers by mixed microbial cultures –
Shabana Basheer
7. Enzymatic synthesis of selected amino acid esters of sugars – K. Lohith
8. Enzymatic synthesis of selected glycosides – G.R. Vijayakumar
9. Lipase catalysed esterification of sugars with alkyl side chain containing amino
acids – B. R. Somashekar
10. Enzymatic Synthesis of selected phenolic and vitamin glycosides - R.
Sivakumar.
R&D PROJECT (S) CARRIED OUT SO FAR:
Sl.
No.
Title of Project
Funding
Agency
Project
No.
Duration
Total
Approved
cost (Rs)
Output
From To
1. Inclusion compounds of
cyclodextrin in food
research
CFTRI
(CSIR)
April `89
March
92
278,000
Paper – 146
Patents – 33
PhDs - 10
Products –
200
Synthetic
Protocols –
2. Use of cyclodextrins for
regio and stereo
selective organic
reactions
CFTRI
(CSIR)
April '92 Dec ‘94 300,000
3. Lipase catalysed Bio-
transformations For
production of High
value food Additives
DBT
GAP
107
Dec 97
Nov
2000
340, 000
4.
Non-Carbohydrate
based bio-plastics -
Pokyhydroxyalkanoates
(PHAs)
CFTRI
(CSIR)
MLP
0902
April
1999
Mar
2001
151678
5
.
Synthesis of some
Selected glycosides And
amino acid esters
Using hydrolytic
enzymes
DST GAP244
May
2003
April
2006
844,653
Synthesis of phenolic
25