mitosis

1. MITOSIS
Presented By : Mariha Fazrin
Rahma Tasnim
Abdullah Numan
Naiyemul Hasan
BIO 101 Presentation

2. What is Mitosis
◦ Discovery
 5 phases
 Significance
 Errors
Content Layout with List

3. What Is Mitosis
-A process where a single cell divides into two identical daughter cells.
-Major purpose of mitosis is for growth and to replace worn out cells.
-Divided into 5 phases.

4. DISCOVERY OF MITOSIS
 Was discovered in frog, rabbit, and catcorneacells in 1873
 Was discovered first time by Otto Butschli
 Was described first time by the Polishhistologist Wacław in 1875 .
 Discovered the stages of mitosis by Walther Flemming.
 Derived from the Greek word “mitos”- Warp thread.

5. Walther Flemming.

6.  DNA in the cell is copied in
preparation for cell division
 Outside of nucleus there are two
centrosomes, each containing a
pair of centrioles
 Microtubules extend from these
centrosomes
Interphase

7. Prophase
 The chromosomes start to
condense
 The mitotic spindle begins to
form
 -The nucleolus disappears

8. Prometaphase
 The nuclear envelope breaks
down .
 -The chromosomes are fully
condensed .
 -The mitotic spindle grows more

9. Metaphase
 All the chromosomes align at the
metaphase plate.
 The two kinetochores of each
chromosome should be attached
to microtubules from opposite
spindle poles.

10. Anaphase
 The sister chromatids pulled
apart by the mitotic spindle
 Pulls one chromatid to one pole
and the other chromatid to the
opposite pole

11. Telophase
 The mitotic spindle is broken
down
 -Two new nuclei form
 -Nuclear membranes and
nucleoli reappear.
 -The chromosomes begin to
decondense and return to their
“stringy” form

13. Significance
 Development and growth
 Cell replacement
 Regeneration
 Asexual reproduction

14. Errors
 During early embryonic
development in humans.
 Cancer
 Chromosome Abnormalities
 Effects on Organelle