Medical Utopias: The Promise of Emerging TechnologiesAlex Tang
Medical utopias are often about good health, absence of suffering, and even delaying of the aging process. The last two decades have seen a tremendous increase in emerging medical technologies to achieve these utopias. The completion of the sequencing of the human genome sets the stage for the next step of genetic and molecular advances. The increase in computing power, storage capacity, connectivity, and the Internet has opened avenues of new diagnostic and therapeutic modalities. The perfecting of sustaining cell growth in vitro and cell nucleus transfer has opened the way to cloning, stem cell harvesting, and a new field of regenerative medicine. However, these emerging technologies bring with them a large number of bioethical concerns that need to be addressed. These concerns involving tissue engineering, bioelectronics, new genetics, cloning, gene therapy, germ-line genome modifications are only the tip of the iceberg. In this paper I will reflect on three areas of concern. Firstly, the emergence of the digital patient will be considered. This digital patient will be deeply formed and informed by health information technology (IT), the social media, and issues involving privacy, confidentiality and data security. Secondly, the direct to customers (DTC) genetic screening tests will be discussed. The ethical issue of buccal swabs taken at home and be tested for genetic diseases and future prediction of other illnesses which is marketed directly to the consumers will be examined. Finally, the development of new pharmaco-therapeutics will be explored. There have been changes in the way new drugs are tested and these changes do raise some ethical concerns. The examination of these ethical issues will be done in the framework of respect for autonomy, beneficence, non-maleficence, and justice.
24x7 Automated Behavior Tracking For Rodent Safety Pharmacology & PhenotypingInsideScientific
Actual Analytics Ltd and its development partners present an exclusive webinar describing the applications of a novel Home Cage Analysis system for tracking behavior in group housed rodents, with retained identity, in regular IVC racked home cages.
In this webinar, Dr. Will Redfern of AstraZeneca and Dr. Sara Wells of MRC Harwell discuss 24/7 monitoring of group-housed rodents in their true IVC racked home cage environment for safety pharmacology and phenotyping applications.
Discussions describe the types of new insights that can be obtained from 24/7 monitoring of research animals including activity differences in single and group animals and body temperature profiles in response to drug treatment. Presenters show how they are using this system in various applications from safety pharmacology in rats through to phenotyping studies in mice.
Project ECHO (Extension for Community Health Outcomes)icornpresentations
Sanjeev Arora MD, Distinguished Professor of Medicine (Gastroenterology/Hepatology); Director of Project ECHO®
Department of Medicine, University of New Mexico Health Sciences Center
Quality and safety in global surgery and healthcare conference presentationDr Edward Fitzgerald
Quality and safety in global surgery and healthcare conference presentation including Lifebox Foundation - presented at the International Student Surgical Network
Medical Utopias: The Promise of Emerging TechnologiesAlex Tang
Medical utopias are often about good health, absence of suffering, and even delaying of the aging process. The last two decades have seen a tremendous increase in emerging medical technologies to achieve these utopias. The completion of the sequencing of the human genome sets the stage for the next step of genetic and molecular advances. The increase in computing power, storage capacity, connectivity, and the Internet has opened avenues of new diagnostic and therapeutic modalities. The perfecting of sustaining cell growth in vitro and cell nucleus transfer has opened the way to cloning, stem cell harvesting, and a new field of regenerative medicine. However, these emerging technologies bring with them a large number of bioethical concerns that need to be addressed. These concerns involving tissue engineering, bioelectronics, new genetics, cloning, gene therapy, germ-line genome modifications are only the tip of the iceberg. In this paper I will reflect on three areas of concern. Firstly, the emergence of the digital patient will be considered. This digital patient will be deeply formed and informed by health information technology (IT), the social media, and issues involving privacy, confidentiality and data security. Secondly, the direct to customers (DTC) genetic screening tests will be discussed. The ethical issue of buccal swabs taken at home and be tested for genetic diseases and future prediction of other illnesses which is marketed directly to the consumers will be examined. Finally, the development of new pharmaco-therapeutics will be explored. There have been changes in the way new drugs are tested and these changes do raise some ethical concerns. The examination of these ethical issues will be done in the framework of respect for autonomy, beneficence, non-maleficence, and justice.
24x7 Automated Behavior Tracking For Rodent Safety Pharmacology & PhenotypingInsideScientific
Actual Analytics Ltd and its development partners present an exclusive webinar describing the applications of a novel Home Cage Analysis system for tracking behavior in group housed rodents, with retained identity, in regular IVC racked home cages.
In this webinar, Dr. Will Redfern of AstraZeneca and Dr. Sara Wells of MRC Harwell discuss 24/7 monitoring of group-housed rodents in their true IVC racked home cage environment for safety pharmacology and phenotyping applications.
Discussions describe the types of new insights that can be obtained from 24/7 monitoring of research animals including activity differences in single and group animals and body temperature profiles in response to drug treatment. Presenters show how they are using this system in various applications from safety pharmacology in rats through to phenotyping studies in mice.
Project ECHO (Extension for Community Health Outcomes)icornpresentations
Sanjeev Arora MD, Distinguished Professor of Medicine (Gastroenterology/Hepatology); Director of Project ECHO®
Department of Medicine, University of New Mexico Health Sciences Center
Quality and safety in global surgery and healthcare conference presentationDr Edward Fitzgerald
Quality and safety in global surgery and healthcare conference presentation including Lifebox Foundation - presented at the International Student Surgical Network
PCHAlliance conducted a systematic review of published literature to gather the available data on health outcome measures, reviewing over 1,450 citations. Fifty-three randomized controlled studies and trials were selected for analysis, on topics related to mobile technologies, remote patient monitoring, web-based counseling and other personal connected health technologies. This publication aims to set an initial baseline for the current body of evidence in personal connected health in key areas, namely behavior change and self-care, remote patient monitoring, remote counseling and mental health, as well as more broadly through key condition-specific studies.
Download the paper here: http://www.pchalliance.org/personal-connected-health-state-evidence-and-call-action
In this global pandemic, IBD patients and their healthcare providers from around the world share similar fears and concerns. SECURE-IBD is an international database to monitor and report on COVID-19 in IBD patients. By working across borders, we are learning how factors like age, other conditions, and IBD treatments impact COVID-19 outcomes. This slide deck also shares information about other research efforts that are ongoing to better understand the impact of COVID-19 on IBD patients.
The Foundation would like to thank AbbVie Inc., Genentech, Inc., Gilead Sciences, Inc., Janssen Biotech, Inc., Shire, and Takeda Pharmaceuticals U.S.A., Inc., sponsors of our COVID-19 materials. Additional support is provided through the Foundation’s annual giving program and individual donors.
Maile Young Karris, MD
Associate Professor
Co-Director San Diego Center for AIDS Research Clinical Investigations Core
Divisions of Infectious Diseases & Global Public Health and Geriatrics & Gerontology
Department of Medicine
University of California San Diego
With @Atreja at the NODE Health Conference - Digital Medicine http://digitalmedicineconference.com/ on the events and studies which moved the field forward
Ομιλία-Παρουσίαση: Γιώτα Τουλούμη, Καθηγήτρια Βιοστατιστικής και Επιδημιολογίας, Εργαστήριο Υγιεινής, Επιδημιολογίας και Ιατρικής Στατιστικής, Ιατρική Σχολή, Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών
Thomas F. Patterson, MD, FACP, FIDSA, and James S. Lewis II, PharmD, FIDSA, prepared useful practice aids pertaining to invasive fungal infections for this CME/MOC/CPE activity titled "Overcoming Barriers to Optimal Diagnosis and Treatment of Invasive Fungal Infections: Practical Guidance for the Hospital-Based Healthcare Provider." For the full presentation, monograph, complete CME/MOC/CPE information, and to apply for credit, please visit us at http://bit.ly/2wc2hy4. CME/MOC/CPE credit will be available until September 3, 2019.
Comparative Effectiveness of a Multifaceted Intervention to Improve Adherence to Annual Colorectal Cancer Screening in Community Health Centers (RCT)
Présentation de David W. Baker au colloque "Recherche interventionnelle contre le cancer : Réunir chercheurs, décideurs et acteurs de terrain » - 17 et 18 novembre 2014, BnF, Paris
I suspect the news my smartphone will soon turn into my doctor is exaggerated. While a consultation with my phone will always be easier to arrange than an appointment with my GP, I know for a fact that even the techiest among us still want to see a living, breathing, qualified person when they’re under the weather.
I say this with confidence as this is one of the key findings from the first ever mHealth report by Ruder Finn. The report, based on a survey of more than 1,000 smartphone and tablet users, shows that while there’s an appetite for healthcare applications, and consumers generally love a good app, developers of health applications have not convinced the public of this kind of app’s value to them. The survey’s results show that apps for social media, games and news are the most popular with users of smartphones and tablets; healthy living apps languish in last place in terms of popularity.
The survey, conducted on our behalf by pollster YouGov, reveals some interesting links between type of device and the likelihood of the user to use health & lifestyle apps. The research suggests apps that help take away some of the pain associated with healthcare – booking appointments and getting hold of test results for example – are more popular than those to actually manage health. Our results suggested a great deal of caution around apps to help patients manage long term health conditions – significantly even among those suffering from chronic disease/ health problems. These findings may come as a disappointment to the World Health Organization, which along with The International Telecommunication Union (ITU), is launching an mHealth initiative to help combat noncommunicable diseases, based on the fact that mHealth is cost effective, scalable and sustainable.
In our survey, there is a difference between the generations and the impact that might have on app usage. While 75% of respondents between 25-34 owned a smartphone fewer than 30% in the 55+ category did. Although everyone accesses healthcare it’s usually the oldest among us who use it most. It will be interesting to see how usage patterns change as the gamers and Tweeters of today get older.
This presentation also contains slides from Prof. Christopher James
Professor of Healthcare Technology (University of Warwick) and
Director, Institute of Digital Healthcare; Dr Tom Barber
Associate Professor and Honorary Consultant Endocrinologist,
University of Warwick and UHCW NHS Trust and Owen Booth
Head of Content, Diabetes UK.
The event can be seen at the hashtag #rfmhealth too.
PCHAlliance conducted a systematic review of published literature to gather the available data on health outcome measures, reviewing over 1,450 citations. Fifty-three randomized controlled studies and trials were selected for analysis, on topics related to mobile technologies, remote patient monitoring, web-based counseling and other personal connected health technologies. This publication aims to set an initial baseline for the current body of evidence in personal connected health in key areas, namely behavior change and self-care, remote patient monitoring, remote counseling and mental health, as well as more broadly through key condition-specific studies.
Download the paper here: http://www.pchalliance.org/personal-connected-health-state-evidence-and-call-action
In this global pandemic, IBD patients and their healthcare providers from around the world share similar fears and concerns. SECURE-IBD is an international database to monitor and report on COVID-19 in IBD patients. By working across borders, we are learning how factors like age, other conditions, and IBD treatments impact COVID-19 outcomes. This slide deck also shares information about other research efforts that are ongoing to better understand the impact of COVID-19 on IBD patients.
The Foundation would like to thank AbbVie Inc., Genentech, Inc., Gilead Sciences, Inc., Janssen Biotech, Inc., Shire, and Takeda Pharmaceuticals U.S.A., Inc., sponsors of our COVID-19 materials. Additional support is provided through the Foundation’s annual giving program and individual donors.
Maile Young Karris, MD
Associate Professor
Co-Director San Diego Center for AIDS Research Clinical Investigations Core
Divisions of Infectious Diseases & Global Public Health and Geriatrics & Gerontology
Department of Medicine
University of California San Diego
With @Atreja at the NODE Health Conference - Digital Medicine http://digitalmedicineconference.com/ on the events and studies which moved the field forward
Ομιλία-Παρουσίαση: Γιώτα Τουλούμη, Καθηγήτρια Βιοστατιστικής και Επιδημιολογίας, Εργαστήριο Υγιεινής, Επιδημιολογίας και Ιατρικής Στατιστικής, Ιατρική Σχολή, Εθνικό και Καποδιστριακό Πανεπιστήμιο Αθηνών
Thomas F. Patterson, MD, FACP, FIDSA, and James S. Lewis II, PharmD, FIDSA, prepared useful practice aids pertaining to invasive fungal infections for this CME/MOC/CPE activity titled "Overcoming Barriers to Optimal Diagnosis and Treatment of Invasive Fungal Infections: Practical Guidance for the Hospital-Based Healthcare Provider." For the full presentation, monograph, complete CME/MOC/CPE information, and to apply for credit, please visit us at http://bit.ly/2wc2hy4. CME/MOC/CPE credit will be available until September 3, 2019.
Comparative Effectiveness of a Multifaceted Intervention to Improve Adherence to Annual Colorectal Cancer Screening in Community Health Centers (RCT)
Présentation de David W. Baker au colloque "Recherche interventionnelle contre le cancer : Réunir chercheurs, décideurs et acteurs de terrain » - 17 et 18 novembre 2014, BnF, Paris
I suspect the news my smartphone will soon turn into my doctor is exaggerated. While a consultation with my phone will always be easier to arrange than an appointment with my GP, I know for a fact that even the techiest among us still want to see a living, breathing, qualified person when they’re under the weather.
I say this with confidence as this is one of the key findings from the first ever mHealth report by Ruder Finn. The report, based on a survey of more than 1,000 smartphone and tablet users, shows that while there’s an appetite for healthcare applications, and consumers generally love a good app, developers of health applications have not convinced the public of this kind of app’s value to them. The survey’s results show that apps for social media, games and news are the most popular with users of smartphones and tablets; healthy living apps languish in last place in terms of popularity.
The survey, conducted on our behalf by pollster YouGov, reveals some interesting links between type of device and the likelihood of the user to use health & lifestyle apps. The research suggests apps that help take away some of the pain associated with healthcare – booking appointments and getting hold of test results for example – are more popular than those to actually manage health. Our results suggested a great deal of caution around apps to help patients manage long term health conditions – significantly even among those suffering from chronic disease/ health problems. These findings may come as a disappointment to the World Health Organization, which along with The International Telecommunication Union (ITU), is launching an mHealth initiative to help combat noncommunicable diseases, based on the fact that mHealth is cost effective, scalable and sustainable.
In our survey, there is a difference between the generations and the impact that might have on app usage. While 75% of respondents between 25-34 owned a smartphone fewer than 30% in the 55+ category did. Although everyone accesses healthcare it’s usually the oldest among us who use it most. It will be interesting to see how usage patterns change as the gamers and Tweeters of today get older.
This presentation also contains slides from Prof. Christopher James
Professor of Healthcare Technology (University of Warwick) and
Director, Institute of Digital Healthcare; Dr Tom Barber
Associate Professor and Honorary Consultant Endocrinologist,
University of Warwick and UHCW NHS Trust and Owen Booth
Head of Content, Diabetes UK.
The event can be seen at the hashtag #rfmhealth too.
Why Precision Medicine and Personalized Healthcare and Why Now? Links to Canada’s Rare Disease Strategy The Future is Now
1) Marc LePage, Genome Canada
2) Michael Duong, Roche
3) Danica Stanimirovic, National Research Council
4) Daniel Gaudet, University of Montreal
5) Christine Dalgleish, Patient Perspective
6) Jamie Bruce, Khure Health
Ομιλία-Παρουσίαση: Agata Jakoncic, Διευθύνουσα Σύμβουλος, MSD Ελλάδας, Κύπρου & Μάλτας
Τίτλος Ομιλίας: «Health Innovation is a prerequisite for sustainable health care systems»
Mobile Health at Ochsner: The Apple HealthKit and Epic EMR IntegrationRahlyn Gossen
These slides are from the April 2, 2015 meeting of Health 2.0 New Orleans with special guest Jonathan Wilt, the Assistant Vice President of the Center for Innovation at Ochsner Health System. Jonathan spoke about Ochsner's Health System's integration of Apple HealthKit with the Epic EMR.
Audio is here: http://www.youtube.com/watch?v=UsSKui7m4VY
EuroBioForum 2013 - Day 1 | Pierre MeulienEuroBioForum
EuroBioForum 2013 2nd Annual Conference
27-28 May 2013 - Hilton Munich City, Munich, Germany
http://www.eurobioforum.eu/2013
=======================================
# NATIONAL PERSPECTIVES #
Canada:
Genomics and personalised health in Canada
Dr Pierre Meulien, President and CEO at Genome Canada
=======================================
http://www.eurobioforum.eu
The benefits of patient involvement in research and development (RE:ACT Congr...jangeissler
Presentation of Jan Geissler, Director EUPATI and Co-Founder CML Advocates Network, about the benefits of involving patients in research and development, and about EUPATI. Held at RE:ACT Conress 2016 on Research of Rare and Orphan Diseases, organized by the Blackswan Foundation on 12 March 2016 in Barcelona, Spain
Effectiveness of Telenursing on Diabetic Patients with Glucose Self Monitorin...ijtsrd
BACKGROUND Diabetes is one of the most common debilitating diseases in the elderly requiring reasonable blood sugar control to prevent complications. Telenursing has been presented as a cost effective method to control blood glucose levels. AIM The present study aims to assess the effect on telenurisng on self glucose control among clients with type to diabetes mellitus at Saveetha medical college and hospital. METHODS AND MATERIALS A quantitative research design was used for the present study. A total 100 samples were collected using quota sampling technique. The demographic variable pretest and posttest level of complaints on self glucose monitoring was assessed using structured questionnaire, telenursing on glucose self monitoring and mangement was given among diabetes mellitus followed by that data was gathered and analyzed. RESULTS The results the study revealed that there is a significant association between the selected demographic variables and posttest level of diabetes mellitus at the level of p 0.01. CONCLUSION Thus, the present despites that factors associated with posttest level of diabetes mellitus among demographic variable. Mrs. Sindhupriya. R | Kanimozhi. N "Effectiveness of Telenursing on Diabetic Patients with Glucose Self-Monitoring among with General Population at Arakkonam GH" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-7 | Issue-5 , October 2023, URL: https://www.ijtsrd.com/papers/ijtsrd60034.pdf Paper Url: https://www.ijtsrd.com/biological-science/other/60034/effectiveness-of-telenursing-on-diabetic-patients-with-glucose-selfmonitoring-among-with-general-population-at-arakkonam-gh/mrs-sindhupriya-r
A global challenge to reduce harm and save livesProqualis
Apresentação de Itziar Larizgoitia Jauregui durante o
Itziar Larizgoitia Jauregui é médica, nascida na Espanha, com atuação em Saúde Pública, com mestrado nessa área e Doutorado em Políticas e Gestão da Saúde. Nos últimos 13 anos, tem atuado como membro da Organização Mundial da Saúde (OMS) em Genebra, Suíça. No total, são mais de 20 anos de experiência nas áreas de Qualidade e Segurança do Paciente, Organização e Reforma de sistemas de saúde.
A device to convert any toilet at an outreach camp or a healthcare facility in to a smart biosensing toilet to screen and/or diagnose chronic kidney disease.
Lustrumlezing paul stoffels de rol van innovatie voor de gezondheidszorg van ...Michiel Stoffels
Ter gelegenheid van het 40 jarig bestaan van de Universiteit werd een reeks lustrumlezingen georganiseerd. Voor de faculteit Gezondheid en Levenswetenschappen hadden we de eer Dr. Paul Stoffels - Worldwide Chairman , Janssen Pharmaceutical Chief Scientific Officer, Johnson & Johnson - te mogen ontvangen.
Similar to Beyond the medical curve presentation (20)
Preventing diabetes and obesity in mental health disordersHealthXn
Diabetes is common in people with mental health disorders. This presentation discusses why and what therapies may worsen the disorder and how to prevent obesity and diabetes
Iodine and the Thyroid: How the thyroid uniquely adapts to its environment to...HealthXn
This presentation describes how the thyroid actively traps iodine, a rare micronutrient, to produce thyroid hormones. Iodine is important for normal fetal and adult development.
This presentation given to the International Society for Enzymology in Corfu details the extent of vitamin D deficiency in the largest state of Australia, NSW. It highlights the over=testing phenomenon that has occurred and how to correct the problem.
The value of health information systems and EMR to patient careHealthXn
This presentation given to the Athena Society in Crete documents the challenges and benefits of health information systems and the difficulties encountered in implementing EMR.
Advances in the diagnosis and treatment for benign and malignant thyroid diseaseHealthXn
Thyroid disorders are common. This presentation reviews the causes of benign thyroid disease as well as therapy, including new therapies for advanced thyroid cancer.
Bridging health care’s innovation education gapHealthXn
Recently I was privileged to be part of a consultation bringing together CEOS in health, academia and business to examine health care's innovation education. Regina Herzlinger and co authors have distilled these consultations into this thought provoking article.
https://hbr.org/2014/11/bridging-health-cares-innovation-education-gap
Prevention against micronutrient malnutritionHealthXn
Micronutrident disorders are common and a major cause of morbidity in all populations. In this presentation we discuss the importance of iodine, folic acid and vitamin D deficiency. Prevention is the solution
The impact of maternal and fetal thyroid hormone deficiency: iodine deficienc...HealthXn
Thyroid hormone deficiency at critical periods of brain development may cause permanent mental and neurological disability and impairment. Iodine deficiency is the commonest preventable cause of mental disability
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
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Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
3. Workflow
Education
Clinical care
Who am I?1
The nature of the health system?2
The drivers for change in health3
The Value of investing in DIGITAL HEALTH4
3COMMUNICATION: CONTENT IS KING | AUGUST 2014
OUTLINE
The impact of digital technology on disease5
Research
6. The nature of patient care is a constant
HEALTH IS A KNOWLEDGE
BASED PROFESSION
Research
Development
Education
Training
Care
Prevention
Generate
Knowledge
Impact
Knowledge
Apply
Knowledge
7. HEALTH WORK IS A BALANCED MATRIX
Technology
Platform
Team and
Workflow Platform
High Touch High Tech
8. THE NATURE OF THE HEALTH SYSTEM
The challenges to the system
9. Challenges to the health system
RISING DEMAND
• Growing & ageing population
• Chronic illness rising
• High levels smoking, obesity, stress
• High consumer expectations
• Patient Safety
• Workforce shortages and attitudes
• Manage demand within finite resources
• Cost vs investment
• NSW spends about 28% of budget on
health care
• 1.3 million dollars per hour
CONSTRAINED CAPACITY
10. Projections of Australian government spending by category (per cent of GDP)
INTERGENERATIONAL REPORT 2010
11. Future industry job growth – Australia 5 years from 2009-10 to 2014-15 (‘000) - DEEWR projections
FUTURE WORKFORCE GROWTH AT FEB 2010
12. Principal Incident Type Number
Fall 13,137
Medication/IV Fluid 10,793
Clinical Management 10,082
Agression-agressor 6,704
Behavior/Human Performance 5,446
Pressure Ulcer 4,512
Documentation 4,182
Accident/occupational health and safety 2,735
Organisation management/service 1,647
Medical device/equipment/property 1,519
Blood/blood product 910
Agression-victim 768
Health care associated infection/infestation 679
Pathology/laboratory 415
Complaint 401
Nutrition 395
Security 228
Building/fittings/fixtures/surrounds 174
Oxygen/gas/vapour 40
Total 64,767
Patient safety
IIMS notifications by principal incident type
July-December 2009
Clinical incident notifications in IIMS
January 2005 – December 2009
14. Investing in health IT perceived as a solution
to some of the challenges
BENEFITS
• Improved automation
• Improved productivity
• Reduced duplication
• Improved safety
• Improved patient and staff experience
• Improved reach of information and service
• Financial investment not realised
• Poor connectivity
• Lack of common standards
• Increased risk to patients
• Increased staff frustration and lower morale
• Staff expectations not realised
• Poor execution and implementation due to
inadequate training
RISKS
16. Bionics
Bionics
(also known as
bionical creativity engineering)
is the application of
biological methods and
systems found in nature
to the study and design
of engineering systems
and modern technology
25. Reference: 1. International Diabetes Federation. Diabetes Atlas 5th ed, 2012 update. Available
from http://www.idf.org/sites/default/files/5E_IDFAtlasPoster_2012_EN.pdf [accessed Nov 2013].
International Diabetes Federation
Diabetes Atlas 2012
26. 900,000 people with T2DM registered on the
National Diabetes Services Scheme²
T2DM in Australia,
June 2013
70,000 additions over the past 12 months²
Total annual cost of T2DM is up to
$6 billion (T1DM $570 million)³
≈ 200 new cases per day²
27. Visual impairmentRenal disease
Neuropathy Cardiovascular disease
Reference:
3. Baker IDI Heart and Diabetes Institute. Diabetes: The silent pandemic and its impact on Australia. Available from
http://www.diabetesaustralia.com.au/Documents/DA/What's%20New/12.03.14%20Diabetes%20management%20booklet%20FINAL.pdf [accessed Nov 2013].
Major complications of diabetes3
28. T2DM is characterized ‘classically’ by insulin resistance and beta-cell dysfunction
Type 2 Diabetes – a progressive disease
AdAdapted from Bailey et al.
Krentz AJ, Bailey CJ. Type 2 Diabetes in Practice. 2nd ed. London, UK: Royal Society of Medicine Press; 2005.
29. 29
Multiple pathophysiological failures contribute
to hyperglycaemia in T2DM
1. Gerich, J. E. Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: therapeutic implications. Diabetic Medicine. 2010;
27: 136-142. 2. Valentine, V. The role of the kidney and sodium-glucose cotransporter-2 inhibition in diabetes management. Clinical Diabetes. 2012; 4: 151-155.
Adapted from Defronzo RA. Diabetes 2009;58:773–95.
35. Case study: MW
35
MW aged 65
First seen 04/2013
Diabetes type 2 30 yrs; on insulin 15 yrs;
hypertension, on insulin 200 units per day
Height 155 cm; weight 140 kg
Poor circulation
Unable to exercise
What is her risk? Would you insure her?
43. 43
Heart disease
Absorb: Background
The goal of this trial was to evaluate the use of
bioabsorbable drug-eluting stent (DES) platform
among patients undergoing elective
percutaneous coronary intervention (PCI) for a
de novo coronary lesion.
The bioabsorbable structure of the stent is made
of polylactic acid, a biodegradable polyester
derived from lactic acid.
47. Clinical Applications of Whole Genome and Exome Sequencing
Diverse applications of WGS in clinical medicine
47
Adapted for Clinical Chemistry from Chrystoja CC, Diamandis EP. Whole Genome Sequencing
as a Diagnostic Test: Challenges and Opportunities. 2013 Nov 13
Clinical
Applications of
Whole Genome and
Exome Sequencing
Individualization
of treatment
Molecular
characterization
of disease
Pharmacogenomics
Population
screening for
disease risk
Prenatal
screening
48. 48
Cost of sequencing one genome
Innovations in chemistry,
optics, fluidics,
computational, hardware and
bioinformatics solutions
50. 50
The $1,000 genome is here
On Jan. 14, 2014,
Illumina reduced the cost of
sequencing by a factor of 10
when it unveiled the HiSeq X.
The machine, about the size of
a large photocopier, can knock
out 20,000 human genomes
per year.
51. 51
World’s largest sequencing operation
Human Longevity Inc.
J. Craig Venter; Robert Hariri and
Peter H. Diamandis
Begin sequencing up to 40,000 human
genomes per year and has plans to scale-
up to 100,000 genomes per year
Genetic and Engineering News, April 2014
53. Obstacles
Obstacles to be addressed to bring WGS into routine clinical use
53
Reduce error rate
Improved
bioinformatic tools
Reduce hidden
sequencing costs
Prospective
clinical trials
Develop quality
assurances &
standardisation
Address ethical &
interpretative concerns
54. Major conclusions of paper
If positive the test was deemed to be clinically useful,
in only one disease (Alzheimer)
54
Disease risk is likely not assessed efficiently
by WGS in the other 23 diseases likely
because environmental factors may have
been dominant over genetic factors
56. Summary
Unprecedented developments in bionic technology for diagnosis and treatment of disease
Changing nature of chronic illness
56
1
2
Need to consider some chronic illnesses more as a disability3
Increasing lifespan for those with chronic illness4
Reversibility of chronic disorders eg heart disease and diabetes5
Impact of genomics on assessing risk6
57. Use insurance as a driver to
improve adherence to therapy
Conclusion
57
Implications for the
insurance industry
Types of policy Coverage