This document provides an overview of the Ayurvedic Pharmacopoeia of India (API) and Ayurvedic Formulary of India (AFI). It discusses that the API is published by the Ministry of Ayush and contains 645 monographs in Part 1 and 202 in Part 2 describing single drugs and their formulations. The AFI contains compound Ayurvedic formulations and has published 444 formulations in Part 1 and 350 in Part 3. The Ayurvedic Pharmacopoeia Committee was established in 1962 to develop standards and monographs for drugs and formulations in the API and AFI.

1. AYURVEDIC
PHARMACOPOEIA OF INDIA
BY
DR. SANAGALA PRIYANKA
DEPARTMENT OF DRAVYA GUNA
PG 1ST YEAR

2. INTRODUCTION
 Pharmacopoeia is an official code containing a
list of established drugs and medicinal
preparations.
 Pharmacopoeia literally means “DRUG MAKING”
 Derived from Greek word- PHARMAKOPOIIA
PHARMAKON- Drug
THE VERB POIIA- Making
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3. AYURVEDIC PHARMACOPOEIA OF INDIA
 API is the book of standards for single drug and
it’s formulations
 Published by ministry of ayush
 Description of each single drug or preparation
included in it are called monographs
 There are 645 monographs in part – 1 and 202
monographs in part - 2
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4. AYURVEDIC PHARMACOPOEIA COMMITTEE
 APC was first functional unit in the department of
ayush.
 Constitution of APC established on 20th sept 1962 by
government of india.
 In April 2006, it was shifted under central council for
research in Ayurveda and siddha (CCRAS)
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5. OFFICIAL AND ESSENTIAL PUBLICATIONS OF
APC
 AYURVEDIC PHARMACOPOEIA OF INDIA
 AYURVEDIC FORMULARY OF INDIA
 ATLAS OF AYURVEDIC PHARMACOPOEIA
OF INDIA
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6. OTHER OFFICIAL MONOGRAPHS
 GERMAN COMMISSION E MONOGRAPHS
 EUROPEAN SCIENTIFIC COOPERATIVE FOR
PHYTOTHERAPY (ESCOP)
 THE AMERICAN HERBAL PHARMACOPOEIA
 WHO MONOGRAPHS
 USP MONOGRAPHS
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8. APC - FUNCTIONS
 To prepare Ayurvedic Pharmacopoeia of single and compound
drugs
 To prescribe the working standards for compound ayurvedic
formulations including tests for identity, purity, strength and
quality so as to ensure uniformity of finished formulations.
 To prepare remaining parts of official formulary of compound
preparations from the classical texts including standardized
composition of reputed institution.
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9. APC - FUNCTIONS
 To develop and standardize methods of preparation, dosage form,
toxicity profile etc.
 To develop quality standards, safety, efficacy profile of
intermediates like extracts of ayurvedic raw drugs.
 To develop quality standards, safety, efficacy profile of different
parts of plants, as well as to include new plants as ayurvedic
drugs.
 Any other matter relating to the quality standards, shelf life,
identification, new formulations.
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10. PROJECTS UNDER APC
 Development of pharmacopoeial standards for single
drug and it’s formulations.
 Isolation of marker compounds of medicinal plants.
 Comparative phyto-chemical screening of roots and
barks vs aerial parts.
 Preparation of hindi version of API.
 Biological activity studies of plant extract.
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11. PROJECTS UNDER APC
 To identify methods and procedures for publication of standards of all
commonly used formulations of AFI.
 Information on ayurvedic formulation regarding
- Distinguishing characters
- Method of preparation and dosage
- Method of administration with anupana
- Toxicity
 To develop quality standards, shelf life, identification, new formulations
including safety, efficacy of intermediate plant extracts.
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12. APC & PLIM
 In 2010 – pharmacopoeia Laboratory for Indigenous Medicines
(PLIM)
 Autonomous body for Indian medicine (Ayurveda, sidda, unani) to
evolve the standards under the guidance of APC
 To analyse the product samples picked up by the drug inspectors
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13. PLIM - OBJECTIVES
 To set and validate standards of drugs
 To provide reference standards
 To impart training to drug inspectors and
analysts
 To provide support to APC
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14. API – PART 1
VOLUME YEAR OF PUBLISHING NUMBER OF MONOGRAPHS
I 1990 80 (raw drugs)
II 1999 78
III 2001 100
IV 2004 68
V 2006 92
VI 2008 101
VII 2008 21(minerals)
VIII 2011 60(on 15 plants)
IX 2016 45 ( dry drugs)
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15. API – PART 2
VOLUME YEAR OF PUBLISHING NUMBER OF MONOGRAPHS
I 2007 50
II 2008 51
III 2010 51
IV 2017 50
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16. API – PART - 2
KALPANA VOL 1 (50) VOL 2 (51) VOL 3 (51)
ARKA - - 12
AVALEHA 12 4 3
CHURNA 11 4 1
GHRITA 12 4 1
GUGGULU 1 13 3
VATI 1 - 11
ASAVA & ARISTA - 24 -
TAILA 6 1 20
KSHARASUTRA - 1 -
KSHARA(5) &
LAVANA(10)
6 - -
LEPA 1 - -
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17. API – SUPPORTING PHARMACOPOEIAL
PUBLICATIONS
 TLC ATLAS OF API PART 1
VOL - 1 – 2009 – 80 MONOGRAPHS
VOL – 3 – 2016 – 99 MONOGRAPHS
 MICROSCOPY AND MACROSCOPY ATLAS OF API –
PART 1
VOL I – 2011 – 80 MONOGRAPHS
VOL V – 2009 – 92 MONOGRAPHS
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18. A TYPICAL MONOGRAPH OF API
 TITLE
 NAME OF MONOGRAPH
 SYNONYMS
 DESCRIPTION (MACROSCOPIC & MICROSCOPIC)
 IDENTITY, PURITY AND STRENGTH
 FOREIGN MATTER
 TOTAL ASH
 ACID-INSOLUBLE ASH
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19. A TYPICAL MONOGRAPH OF API
 ALCOHOL - SOLUBLE EXTRACTIVE
 WATER – SOLUBLE EXTRACTIVE
 ASSAYS AND TESTS
 CONSTITUENTS
 PROPERTIES AND ACTION
 IMPORTANT FORMULATIONS
 THERAPEUTIC USES
 DOSE
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20. AYURVEDIC FORMULARY OF INDIA

21. AFI (FORMULATIONS)
 FORMULATION IS DEFINED AS USE OF MORE THAN ONE DRUG IN
MEDICINAL PREPARATION.
The 1st part of ayurvedic formularly in English was published in
1978
 This was the 1st attempt of APC to compile the information
scattered about ayurvedic compound formulations in such a way
to make it suitable to develop pharmacopoeial standard and to
meet the requirements of drug and cosmetic act
 List of single drugs of animal, mineral and plant origin has been
prepared on the basis of names appeared in the formulations.
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22. AFI ( FORMULATIONS)
 Compound formulations are divided into two groups
1. kasthaushadhi (predominantly plant drugs)
2. Rasaushadi ( metals and minerals)
 Kasthaushadhi – asava, arista, avaleha, ghrita, churna, taila
 Rasaushadhi – bhasma, pisti, lauha, mandura, kupipakva rasayana
 Both 1st and 2nd part contain majority of formulations
manufactured as per classics
3rd Part has formulations that has been used by hospital
pharmacies for over 50 years
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23. GENERAL STRUCTURE OF AFI (FORMULATIONS)
 TITLE
 METHOD OF PREPARATION
 DOSE
 ANUPANA
 THEURAPEUTIC USES
 STORAGE
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24. AFI - PUBLICATIONS
PART YEAR OF PUBLISHING NUMBER OF MONOGRAPHS
I 1976 444
II 2000 192
III 2011 350
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25. PART 1 PART 2 PART 3
ASAVA & ARISTA 37 3 17
ARKA 4 2 14
AVALEHA 32 7 20
KWATHA CHURNA 9 25 30
GUGGULU 12 2 7
GHRITA 44 4 -
CHURNA 40 6 69
TAILA 62 18 26
DRAVAKA 1 - -
LAVANA & KSHARA 13 - 2
LEPA 12 5 23
VATI & GUTIKA 35 14 26
VARTI, NETRA
BINDU, ANJANA
8 2 2
SATWA 1 - -
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26. PART 1 PART 2 PART 3
KUPIPAKVA
RASAYANA
10 - -
PARPATI 5 2 1
PISHTI 4 2 1
BHASMA 20 5 -
MANDURA 2 3 4
RASAYOGA 55 69 96
LAUHA 12 9 11
DHUPA - - 1
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27. CONCLUSION
 API IS A BOOK OF AYURVEDIC MONOGRAPHS WHICH GIVES
PHYSICAL PROPERTIES, MICROSCOPIC & MACROSCOPIC
CHARACTERS, IDENTITY TESTS, CONSTITUENTS, APPROVED
THERAPEUTIC USES, MINIMUM AND MAXIMUM DOSES, COLOUR
PHOTOGRAPHS, CHEMICAL FORMULATIONS AND STANDARDS OF
QUALITY OF CRUDE DRUGS INCLUDING ITS FORMULATIONS.
 THE AIM HAS BEEN SET STANDARDS FOR QUALITY, EFFICACY AND
SAFETY IN ORDER THAT MANY TRADITIONAL HERBS AND
FORMULATIONS MEET LEGAL REQUIREMENT.
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28. THANK YOU