The document discusses the criteria for diagnosing atopic dermatitis. It describes the Hanifin and Rajka criteria, which includes major criteria like pruritus, characteristic skin lesions, lichenification in skin folds, and a history of family atopy. Minor criteria include features like ichthyosis, xerosis, positive skin tests, high IgE levels, early age of onset, vulnerability to infections like Staphylococcus, and nipple eczema. The criteria are used to diagnose atopic dermatitis based on the presence of a minimum number of major and minor criteria.
Basic Concepts, Explanation, and Application. Fundamental Remote Sensing; Advantage/ disadvantages, Imaging/non Imaging sensors, RAR and SAR, SAR Geometry, Resolutions in the microwave, Geometric Distortions in SAR, Polarization in SAR, Target Interaction, SAR Interferometry
Tecniche e metodi di studio dello stato delle coste in ambiente GISPlanetek Italia Srl
Definizione della linea di costa italiana e delle opere di difesa. Studio dello stato delle coste italiane e della loro evoluzione.
Presentazione per l'evento Euro P.A. HydroGeo 2006.
A cura del Servizio Difesa delle Coste APAT (oggi ISPRA) in collaborazione con
Planetek Italia s.r.l.
dettagli:
http://www.planetek.it/progetti/sistema_informativo_geografico_costiero_italiano
Robert Sidbury, MD, MPH, and Ruchi S. Gupta, MD, MPH, prepared useful practice aids pertaining to atopic dermatitis for this CME activity titled "A Closer Look at the Atopic Dermatitis Patient Journey: Effective Management Approaches Across the Age and Disease Spectrum." For the full presentation, monograph, complete CME information, and to apply for credit, please visit us at http://bit.ly/2PpDRMR. CME credit will be available until November 12, 2020.
Basic Concepts, Explanation, and Application. Fundamental Remote Sensing; Advantage/ disadvantages, Imaging/non Imaging sensors, RAR and SAR, SAR Geometry, Resolutions in the microwave, Geometric Distortions in SAR, Polarization in SAR, Target Interaction, SAR Interferometry
Tecniche e metodi di studio dello stato delle coste in ambiente GISPlanetek Italia Srl
Definizione della linea di costa italiana e delle opere di difesa. Studio dello stato delle coste italiane e della loro evoluzione.
Presentazione per l'evento Euro P.A. HydroGeo 2006.
A cura del Servizio Difesa delle Coste APAT (oggi ISPRA) in collaborazione con
Planetek Italia s.r.l.
dettagli:
http://www.planetek.it/progetti/sistema_informativo_geografico_costiero_italiano
Robert Sidbury, MD, MPH, and Ruchi S. Gupta, MD, MPH, prepared useful practice aids pertaining to atopic dermatitis for this CME activity titled "A Closer Look at the Atopic Dermatitis Patient Journey: Effective Management Approaches Across the Age and Disease Spectrum." For the full presentation, monograph, complete CME information, and to apply for credit, please visit us at http://bit.ly/2PpDRMR. CME credit will be available until November 12, 2020.
The purpose of choosing this topic is to aware you about sentinel satellites that leads to new discoveries and ultimately changes the arena of Remote Sensing.
Analisi comparativa del Marketing mix nelle imprese nautiche da diportodamiano cori
Lo studio della tesi svolta mira a configurare il mercato nautico, a individuare i
comportamenti delle varie imprese nautiche nei differenti segmenti di mercato. Qual è
l‟orientamento del mercato nautico? Qual‟è la domanda globale e il dimensionamento
dell‟offerta nautica? Domande a cui daremo risposta nelle pagine successive, rivolte
inoltre a inquadrare attraverso le azioni di marketing mix la programmazione dei
prodotti, la promozione della domanda e l‟esecuzione della vendita. Conoscere come si
articolano le strategie aziendali, se ci sono o meno analogie tra i vari competitors e/o tra
i diversi mercati. Descrivere la filiera nautica e scoprire i rapporti di sincronizzazioni
con i mercati di riferimento; misurare le quote di mercato delle imprese nautiche e i
vantaggi competitivi nei loro segmenti di riferimento. L‟obiettivo del lavoro di tesi è
stato analizzare i segmenti di mercato sotto il profilo delle 4 leve del marketing mix:
Prodotto, Prezzo, Distribuzione e Comunicazione. Le finalità saranno, dopo aver creato un profilo di ogni segmento di mercato ed aver definito ciascuna impresa nautica
all'interno del proprio micro segmento, aver prodotto un‟analisi comparativa tra le
diverse strategie di marketing mix dei diversi players operanti all'interno del mercato
nautico internazionale anche nell'ottica di “strategic product development” tesa a
pianificare, attuare e controllare il posizionamento competitivo all'interno del segmento
di mercato selezionato. L‟analisi comparativa adottata sarà caratterizzata da un
complesso di attività interne ed esterne finalizzate a misurare le capacità competitive
delle imprese attraverso la rilevazione delle prestazioni dei singoli prodotti e servizi,
nonché sull'importanza ad essi attribuita ai differenti fattori caratterizzanti il mix
d‟offerta.
The purpose of choosing this topic is to aware you about sentinel satellites that leads to new discoveries and ultimately changes the arena of Remote Sensing.
Analisi comparativa del Marketing mix nelle imprese nautiche da diportodamiano cori
Lo studio della tesi svolta mira a configurare il mercato nautico, a individuare i
comportamenti delle varie imprese nautiche nei differenti segmenti di mercato. Qual è
l‟orientamento del mercato nautico? Qual‟è la domanda globale e il dimensionamento
dell‟offerta nautica? Domande a cui daremo risposta nelle pagine successive, rivolte
inoltre a inquadrare attraverso le azioni di marketing mix la programmazione dei
prodotti, la promozione della domanda e l‟esecuzione della vendita. Conoscere come si
articolano le strategie aziendali, se ci sono o meno analogie tra i vari competitors e/o tra
i diversi mercati. Descrivere la filiera nautica e scoprire i rapporti di sincronizzazioni
con i mercati di riferimento; misurare le quote di mercato delle imprese nautiche e i
vantaggi competitivi nei loro segmenti di riferimento. L‟obiettivo del lavoro di tesi è
stato analizzare i segmenti di mercato sotto il profilo delle 4 leve del marketing mix:
Prodotto, Prezzo, Distribuzione e Comunicazione. Le finalità saranno, dopo aver creato un profilo di ogni segmento di mercato ed aver definito ciascuna impresa nautica
all'interno del proprio micro segmento, aver prodotto un‟analisi comparativa tra le
diverse strategie di marketing mix dei diversi players operanti all'interno del mercato
nautico internazionale anche nell'ottica di “strategic product development” tesa a
pianificare, attuare e controllare il posizionamento competitivo all'interno del segmento
di mercato selezionato. L‟analisi comparativa adottata sarà caratterizzata da un
complesso di attività interne ed esterne finalizzate a misurare le capacità competitive
delle imprese attraverso la rilevazione delle prestazioni dei singoli prodotti e servizi,
nonché sull'importanza ad essi attribuita ai differenti fattori caratterizzanti il mix
d‟offerta.
hanifin and rajka criteria, entymology, definition of AD, atopy, etiopathogenesis of AD, genetics in AD, filaggrin, epidermal barrier dysfunction, atopic march, hygiene hypothesis, infantile phase of AD, childhood phase of AD, adult phase of AD, pityriasis alba, denne morgan folds, dirty neck appearence, nipple dermatitis, hanifin and rajka criteria, UK refinement of hanifin and rajka criteria, millenium criteria of AD, japanese dermatological association criteria, management of AD, wet wrap therapy,
Dermatology Review Booklet by Dr. Aryan (Medical Booklet Series by Dr. Aryan ...Dr. Aryan (Anish Dhakal)
This is a part of free booklet series designed by Dr. Aryan for rapid review of basic concepts of medical science. I grant you right to share the booklet for fair use (teaching, scholarship, education and research) anywhere in the world exclusively for non-monetary purposes.
LEPROSY
CELLULITIS
IMPETIGO
LEPROSY REVISION NOTES FOR NEET PG AIIMS PREPARATION
WITH HIGH YIELD TOPICS BASED ON LECTURE NOTES AND PREVIOUS YEAR QUESTIONS
\\
June 3, 2024 Anti-Semitism Letter Sent to MIT President Kornbluth and MIT Cor...Levi Shapiro
Letter from the Congress of the United States regarding Anti-Semitism sent June 3rd to MIT President Sally Kornbluth, MIT Corp Chair, Mark Gorenberg
Dear Dr. Kornbluth and Mr. Gorenberg,
The US House of Representatives is deeply concerned by ongoing and pervasive acts of antisemitic
harassment and intimidation at the Massachusetts Institute of Technology (MIT). Failing to act decisively to ensure a safe learning environment for all students would be a grave dereliction of your responsibilities as President of MIT and Chair of the MIT Corporation.
This Congress will not stand idly by and allow an environment hostile to Jewish students to persist. The House believes that your institution is in violation of Title VI of the Civil Rights Act, and the inability or
unwillingness to rectify this violation through action requires accountability.
Postsecondary education is a unique opportunity for students to learn and have their ideas and beliefs challenged. However, universities receiving hundreds of millions of federal funds annually have denied
students that opportunity and have been hijacked to become venues for the promotion of terrorism, antisemitic harassment and intimidation, unlawful encampments, and in some cases, assaults and riots.
The House of Representatives will not countenance the use of federal funds to indoctrinate students into hateful, antisemitic, anti-American supporters of terrorism. Investigations into campus antisemitism by the Committee on Education and the Workforce and the Committee on Ways and Means have been expanded into a Congress-wide probe across all relevant jurisdictions to address this national crisis. The undersigned Committees will conduct oversight into the use of federal funds at MIT and its learning environment under authorities granted to each Committee.
• The Committee on Education and the Workforce has been investigating your institution since December 7, 2023. The Committee has broad jurisdiction over postsecondary education, including its compliance with Title VI of the Civil Rights Act, campus safety concerns over disruptions to the learning environment, and the awarding of federal student aid under the Higher Education Act.
• The Committee on Oversight and Accountability is investigating the sources of funding and other support flowing to groups espousing pro-Hamas propaganda and engaged in antisemitic harassment and intimidation of students. The Committee on Oversight and Accountability is the principal oversight committee of the US House of Representatives and has broad authority to investigate “any matter” at “any time” under House Rule X.
• The Committee on Ways and Means has been investigating several universities since November 15, 2023, when the Committee held a hearing entitled From Ivory Towers to Dark Corners: Investigating the Nexus Between Antisemitism, Tax-Exempt Universities, and Terror Financing. The Committee followed the hearing with letters to those institutions on January 10, 202
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
Operation “Blue Star” is the only event in the history of Independent India where the state went into war with its own people. Even after about 40 years it is not clear if it was culmination of states anger over people of the region, a political game of power or start of dictatorial chapter in the democratic setup.
The people of Punjab felt alienated from main stream due to denial of their just demands during a long democratic struggle since independence. As it happen all over the word, it led to militant struggle with great loss of lives of military, police and civilian personnel. Killing of Indira Gandhi and massacre of innocent Sikhs in Delhi and other India cities was also associated with this movement.
Normal Labour/ Stages of Labour/ Mechanism of LabourWasim Ak
Normal labor is also termed spontaneous labor, defined as the natural physiological process through which the fetus, placenta, and membranes are expelled from the uterus through the birth canal at term (37 to 42 weeks
2. Atopic dermatitis is a disease that begin to arise at
the age of infants and children
characterized by itching of the skin.
chronic and relapsing
inflammatory reaction
based on hereditary factors and environmental
factors,
the symptoms are chronic recurrent erythema,
papules, vesicles, crusting, and skuama.
2Prof DR Dr Ariyanto Harsono SpA(K)
9. Major criteria (minimal 3)
•Pruritus
•Characteristic Distribution and morphology of skin lesions
•Flexural Lichenification
•Facial and extensor Lichenification in babies and children
•Chronic
•History of family atopy
9Prof DR Dr Ariyanto Harsono SpA(K)
Hanifin and Rajka criteria
10. •Pruritus
•Characteristic Distribution
and morphology of skin lesions
•Flexural Lichenification
•Facial and extensor
Lichenification in babies and children
•Kronik
•History of family atopy
10Prof DR Dr Ariyanto Harsono SpA(K)
Hanifin and Rajka criteria
Major criteria (minimal 3)
11. •Pruritus
•Characteristic Distribution
and morphology of skin lesions
•Flexural Lichenification
•Facial and extensor
Lichenification in babies and
children
•Kronik
•History of family atopy
11Prof DR Dr Ariyanto Harsono SpA(K)
Hanifin and Rajka criteria
Major criteria (minimal 3)
12. •Pruritus
•Characteristic Distribution
and morphology of skin lesions
•Flexural Lichenification
•Facial dan ekstensor pada bayi
dan anak
•Kronik
•History of family atopy
12Prof DR Dr Ariyanto Harsono SpA(K)
Hanifin and Rajka criteria
Major criteria (minimal 3)
13. Kriteria Hanifin and Rajka
•Pruritus
•Characteristic Distribution
and morphology of skin lesions
•Flexural Lichenification
•Facial and extensor in babies
and children
•Chronic
•History of family atopy
13Prof DR Dr Ariyanto Harsono SpA(K)
Hanifin and Rajka criteria
Major criteria (minimal 3)
14. 14Prof DR Dr Ariyanto Harsono SpA(K)
•Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections (Stafilokokus/herpes)
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
Hanifin and Rajka criteria
Minor criteria (minimal 3)
15. 15Prof DR Dr Ariyanto Harsono SpA(K)
•Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections (Stafilokokus/herpes)
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
Hanifin and Rajka criteria
Minor criteria (minimal 3)
16. •Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections (Stafilokokus/herpes)
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
16
Hanifin and Rajka criteria
Minor criteria (minimal 3)
17. •Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections (Stafilokokus/herpes)
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
17
Hanifin and Rajka criteria
Minor criteria (minimal 3)
18. •Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections (Stafilokokus/herpes)
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
18Prof DR Dr Ariyanto Harsono SpA(K)
Hanifin and Rajka criteria
Minor criteria (minimal 3)
19. •Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections (Stafilokokus/herpes)
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
19Prof DR Dr Ariyanto Harsono SpA(K)
Hanifin and Rajka criteria
Minor criteria (minimal 3)
20. •Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections (Stafilokokus/herpes)
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
20Prof DR Dr Ariyanto Harsono SpA(K)
Hanifin and Rajka criteria
Minor criteria (minimal 3)
21. 21Prof DR Dr Ariyanto Harsono SpA(K)
•Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections (Stafilokokus/herpes)
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
Hanifin and Rajka criteria
Minor criteria (minimal 3)
22. 22
•Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
Hanifin and Rajka criteria
Minor criteria (minimal 3)
•Vulnerable of infections (Stafilokokus/herpes)
23. 23Prof DR Dr Ariyanto Harsono SpA(K)
•Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections (Staphylococcus/herpes)
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
Hanifin and Rajka criteria
Minor criteria (minimal 3)
24. 24Prof DR Dr Ariyanto Harsono SpA(K)
•Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections (Stafilokokus/herpes)
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
Hanifin and Rajka criteria
Minor criteria (minimal 3)
25. 25Prof DR Dr Ariyanto Harsono SpA(K)
•Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections (Stafilokokus/herpes)
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
Hanifin and Rajka criteria
Minor criteria (minimal 3)
26. 26
•Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
Hanifin and Rajka criteria
Minor criteria (minimal 3)
27. 27Prof DR Dr Ariyanto Harsono SpA(K)
•Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Skin Test positive
•High IgE levels
•Early Onset of age
•Vulnerable of infections (Stafilokokus/herpes)
•Tend to nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Recurrent Conjunctivitis
Hanifin and Rajka criteria
Minor criteria (minimal 3)
28. •Ichtyosis , palmar hyperlinearity, keratosis pilaris
•Xerosis
•Tes kulit positif
•Peningkatan IgE serum
•Onset usia muda
•Mudah infeksi kulit (Stafilokokus/herpes)
•Kecenderungan nonspesific dermatitis
•Nipple eczema
•Cheilitis
•Reccurent conjunctivitis
28Prof DR Dr Ariyanto Harsono SpA(K)
Hanifin and Rajka criteria
Minor criteria (minimal 3)
29. Kriteria Hanifin and Rajka
29Prof DR Dr Ariyanto Harsono SpA(K)
•Dennie Morgan infraorbital fold
•Keratoconus
•Anterior subcapsular cataract
•Orbital darkening
•Facial pallor/erythem
•Pityriasis alba
•Itch when sweating
•Wool intolerant /lipid solvent
•Perifollicular accentuation
•Food Intolerant
•Emotional and environmental influence
•White dermatographism
Hanifin and Rajka criteria
Minor criteria
30. Kriteria Hanifin and Rajka
30Prof DR Dr Ariyanto Harsono SpA(K)
•Dennie Morgan infraorbital fold
•Keratoconus
•Anterior subcapsular cataract
•Orbital darkening
•Facial pallor/erythem
•Pityriasis alba
•Itch when sweating
•Wool intolerant /lipid solvent
•Perifollicular accentuation
•Food Intolerant
•Emotional and environmental influence
•White dermatographism
Hanifin and Rajka criteria
Minor criteria
31. 31Prof DR Dr Ariyanto Harsono SpA(K)
•Dennie Morgan infraorbital fold
•Keratoconus
•Anterior subcapsular cataract
•Orbital darkening
•Facial pallor/erythem
•Pityriasis alba
•Itch when sweating
•Wool intolerant /lipid solvent
•Perifollicular accentuation
•Food Intolerant
•Emotional and environmental influence
•White dermatographism
Hanifin and Rajka criteria
Minor criteria
32. 32Prof DR Dr Ariyanto Harsono SpA(K)
•Dennie Morgan infraorbital fold
•Keratoconus
•Anterior subcapsular cataract
•Orbital darkening
•Facial pallor/erythem
•Pityriasis alba
•Itch when sweating
•Wool intolerant /lipid solvent
•Perifollicular accentuation
•Food Intolerant
•Emotional and environmental influence
•White dermatographism
Hanifin and Rajka criteria
Minor criteria
33. 33Prof DR Dr Ariyanto Harsono SpA(K)
•Dennie Morgan infraorbital fold
•Keratoconus
•Anterior subcapsular cataract
•Orbital darkening
•Facial pallor/erythem
•Pityriasis alba
•Itch when sweating
•Wool intolerant /lipid solvent
•Perifollicular accentuation
•Food Intolerant
•Emotional and environmental influence
•White dermatographism
Hanifin and Rajka criteria
Minor criteria
34. Kriteria Hanifin and Rajka
•Dennie Morgan infraorbital fold
•Keratoconus
•Anterior subcapsular cataract
•Orbital darkening
•Facial pallor/erythem
•Pityriasis alba
•Itch when sweating
•Wool intolerant /lipid solvent
•Perifollicular accentuation
•Food Intolerant
•Emotional and environmental influence
•White dermatographism 34Prof DR Dr Ariyanto Harsono SpA(K)
Hanifin and Rajka criteria
Minor criteria
35. Kriteria Hanifin and Rajka
•Dennie Morgan infraorbital fold
•Keratoconus
•Anterior subcapsular cataract
•Orbital darkening
•Facial pallor/erythem
•Pityriasis alba
•Itch when sweating
•Wool intolerant /lipid solvent
•Perifollicular accentuation
•Food Intolerant
•Emotional and environmental influence
•White dermatographism 35Prof DR Dr Ariyanto Harsono SpA(K)
Hanifin and Rajka criteria
Minor criteria
36. Kriteria Hanifin and Rajka
36Prof DR Dr Ariyanto Harsono SpA(K)
•Dennie Morgan infraorbital fold
•Keratoconus
•Anterior subcapsular cataract
•Orbital darkening
•Facial pallor/erythem
•Pityriasis alba
•Itch when sweating
•Wool intolerant /lipid solvent
•Perifollicular accentuation
•Food Intolerant
•Emotional and environmental influence
•White dermatographism
Hanifin and Rajka criteria
Minor criteria
37. Kriteria Hanifin and Rajka
37Prof DR Dr Ariyanto Harsono SpA(K)
•Dennie Morgan infraorbital fold
•Keratoconus
•Anterior subcapsular cataract
•Orbital darkening
•Facial pallor/erythem
•Pityriasis alba
•Itch when sweating
•Wool intolerant /lipid solvent
•Perifollicular accentuation
•Food Intolerant
•Emotional and environmental influence
•White dermatographism
Hanifin and Rajka criteria
Minor criteria
38. Kriteria Hanifin and Rajka
38Prof DR Dr Ariyanto Harsono SpA(K)
•Dennie Morgan infraorbital fold
•Keratoconus
•Anterior subcapsular cataract
•Orbital darkening
•Facial pallor/erythem
•Pityriasis alba
•Itch when sweating
•Wool intolerant /lipid solvent
•Perifollicular accentuation
•Food Intolerant
•Emotional and environmental influence
•White dermatographism
Hanifin and Rajka criteria
Minor criteria
39. Kriteria Hanifin and Rajka
39Prof DR Dr Ariyanto Harsono SpA(K)
•Dennie Morgan infraorbital fold
•Keratoconus
•Anterior subcapsular cataract
•Orbital darkening
•Facial pallor/erythem
•Pityriasis alba
•Itch when sweating
•Wool intolerant /lipid solvent
•Perifollicular accentuation
•Food Intolerant
•Emotional and environmental influence
•White dermatographism
Hanifin and Rajka criteria
Minor criteria
40. Hanifin and Rajka criteria
Minor criteria
40Prof DR Dr Ariyanto Harsono SpA(K)
•Dennie Morgan infraorbital fold
•Keratoconus
•Anterior subcapsular cataract
•Orbital darkening
•Facial pallor/erythem
•Pityriasis alba
•Itch when sweating
•Wool intolerant /lipid solvent
•Perifollicular accentuation
•Food Intolerant
•Emotional and environmental influence
•White dermatographism
41. Hanifin and Rajka criteria for baby
Kriteria mayor (minimal 2 mayor)
•History of family atopy
•Evidence of pruritic Dermatitis
•Dermatitis fasial, ekstensor, lichenification
Minor criteria (minimal 1 minor)
•Xerosis/ichtyosis/hyperlinear palm
•Perifollicular accentuation
•Chronic scalp scalling
•Periauricular fissures
41Prof DR Dr Ariyanto Harsono SpA(K)
Major criteria(minimal 2 major)
42. Hanifin and Rajka criteria for baby
Kriteria mayor (minimal 2 mayor)
•History of family atopy
•Evidence of pruritic Dermatitis
•Dermatitis fasial, ekstensor, lichenification
Minor criteria (minimal 1 minor)
•Xerosis/ichtyosis/hyperlinear palm
•Perifollicular accentuation
•Chronic scalp scalling
•Periauricular fissures
42Prof DR Dr Ariyanto Harsono SpA(K)
Major criteria(minimal 2 major)
43. Hanifin and Rajka criteria for baby
Kriteria mayor (minimal 2 mayor)
•History of family atopy
•Evidence of pruritic Dermatitis
•Dermatitis fasial, ekstensor, lichenification
Minor criteria(minimal 1 minor)
•Xerosis/ichtyosis/hyperlinear palm
•Perifollicular accentuation
•Chronic scalp scalling
•Periauricular fissures
43Prof DR Dr Ariyanto Harsono SpA(K)
Major criteria(minimal 2 major)
44. Hanifin and Rajka criteria for baby
Major criteria(minimal 2 major)
•History of family atopy
•Evidence of pruritic Dermatitis
•Dermatitis fasial, ekstensor, lichenification
Minor criteria (minimal 1 minor)
•Xerosis/ichtyosis/hyperlinear palm
•Perifollicular accentuation
•Chronic scalp scalling
•Periauricular fissures
44Prof DR Dr Ariyanto Harsono SpA(K)
45. Hanifin criteria for children
Major criteria (minimal 3 major)
•Pruritus
•Characteristic Distribution and morphology of skin lesions
•Dermatitis fasial, ekstensor selama bayi dan awal usia anak
•Flexural lichenification dan linearity by adolescence
•Chronic Dermatitis
Minor criteria(minimal 1 minor)
•Xerosis/ichtyosis/hyperlinear palm/keratosis pilaris
•IgE reactivity
•Chronic scalp scalling
•Perifollicular accentuation
•Periauricular fissures 45Prof DR Dr Ariyanto Harsono SpA(K)
46. Minor criteria(minimal 1 minor)
•Hand/foot dermatitis
•Cheilitis
•Vulnerable to infection (Herpes/Strep/S aureus)
46Prof DR Dr Ariyanto Harsono SpA(K)
47. Minor criteria(minimal 1 minor)
•Hand/foot dermatitis
•Cheilitis
•Vulnerable to skin infetions (Herpes/Strep/S aureus)
47Prof DR Dr Ariyanto Harsono SpA(K)
48. Minor criteria(minimal 1 minor)
•Hand/foot dermatitis
•Cheilitis
•Vulnerable to skin infetions (Herpes/Strep/S aureus)
48Prof DR Dr Ariyanto Harsono SpA(K)
49. Minor criteria(minimal 1 minor)
•Hand/foot dermatitis
•Cheilitis
•Vulnerable to skin infetions (Herpes/Strep/staphilococcus)
49Prof DR Dr Ariyanto Harsono SpA(K)
50. 50Prof DR Dr Ariyanto Harsono SpA(K)
Seborrhoic dermatitis
55. Conventional Therapy
is not always safe
Topical steroid: cutaneous atrophy, striae, bruisability, telangiectasia
High-potency topical steroids can cause
systemic side effects in children.
55Prof DR Dr Ariyanto Harsono SpA(K)
56. Mild Moderate Severe
Mild to Moderate Potency Topical Steroids
Pimecrolimus
Tacrolimus
Oral Steroids
Cyclosporine, mycophenolate
Light treatment
New Treatment Strategy in AD
Emolient
Dry
skin
Itching and/or early sign of
inflammation
Flare
56Prof DR Dr Ariyanto Harsono SpA(K)
IVIG
57. Arachidonic Acid (ARA)
Phospholiphase A
Cyccloxygenase Lipoxygenase
Prostaglandine
TXA
Prostacyclin
Leukotriene A
Leukotriene B
Leukotriene C
γ-linoleic acid
HETE,5-HETE, PAF
57Prof DR Dr Ariyanto Harsono SpA(K)
58. Mechanism of IVIG blocking apoptosis via
Procaspase-8 pathway
Macrophage Keratinocyte
58Prof DR Dr Ariyanto Harsono
SpA(K)
Use of IVIG