This presentation contains the Definition of Eczema, Histology ,Classification ,Clinical manifestation, Differential Diagnosis, Complication, Investigation ,Treatment. it covers briefly the topic related with eczema so the reader will be able to study all aspects related with eczema
INTRODUCTION OF PSORIASIS, EPIDEMIOLOGY OF PSORIASIS, CLINICAL FEATURES OF PSORIASIS, PROGNOSIS OF PSORIASIS, HISTOPATHOLOGY OF PSORIASIS, TRIGGERING FACTORS OF PSORIASIS, PATHOGENESIS OF PSORIASIS
This presentation contains the Definition of Eczema, Histology ,Classification ,Clinical manifestation, Differential Diagnosis, Complication, Investigation ,Treatment. it covers briefly the topic related with eczema so the reader will be able to study all aspects related with eczema
INTRODUCTION OF PSORIASIS, EPIDEMIOLOGY OF PSORIASIS, CLINICAL FEATURES OF PSORIASIS, PROGNOSIS OF PSORIASIS, HISTOPATHOLOGY OF PSORIASIS, TRIGGERING FACTORS OF PSORIASIS, PATHOGENESIS OF PSORIASIS
Rosacea is a chronic (long-term) disease
that affects the skin and sometimes the eyes. The disorder is characterized by
redness, pimples, and, in advanced stages, thickened skin. Rosacea usually
affects the face. Skin on other parts of the upper body is only rarely
involved.
The word Psoriasis is derived from Greek word ‘Psora’ means itching.
Psoriasis is a chronic skin disease results in patches of thick red skin covered with the silvery scales.
It affect approximately 2% of the population.
It occurs in any age group, most commonly occur in people between 15 – 35 years of age.
eczema, is inflammation of the skin. It is characterized by itchy, erythematous, vesicular, weeping, and crusting patches. The term eczema is also commonly used to describe atopic dermatitis
This is a seminar conducted by 4th year medical student under supervision of a lecturer. Sorry for not attaching the references.
Information were from few textbooks, google and also from previous dermatology posting group's seminar.
Atopic eczema is a chronic, relapsing, inflammatory skin condition characterised by an itchy red rash that favours the skin creases such as the folds of the elbows or behind the knees.
An educational presentation that consists of general complaint of skin diseases, history taking and examining various lesions and differentiating it and lastly tools required and investigation to be done to diagnose the skin manifestations
Rosacea is a chronic (long-term) disease
that affects the skin and sometimes the eyes. The disorder is characterized by
redness, pimples, and, in advanced stages, thickened skin. Rosacea usually
affects the face. Skin on other parts of the upper body is only rarely
involved.
The word Psoriasis is derived from Greek word ‘Psora’ means itching.
Psoriasis is a chronic skin disease results in patches of thick red skin covered with the silvery scales.
It affect approximately 2% of the population.
It occurs in any age group, most commonly occur in people between 15 – 35 years of age.
eczema, is inflammation of the skin. It is characterized by itchy, erythematous, vesicular, weeping, and crusting patches. The term eczema is also commonly used to describe atopic dermatitis
This is a seminar conducted by 4th year medical student under supervision of a lecturer. Sorry for not attaching the references.
Information were from few textbooks, google and also from previous dermatology posting group's seminar.
Atopic eczema is a chronic, relapsing, inflammatory skin condition characterised by an itchy red rash that favours the skin creases such as the folds of the elbows or behind the knees.
An educational presentation that consists of general complaint of skin diseases, history taking and examining various lesions and differentiating it and lastly tools required and investigation to be done to diagnose the skin manifestations
Definition, development, function & Site-specific of Melanocyte Definition, formation & function of Melanosomes, Definition & function of Melanin
Melanogenesis
Psoriasis is a skin disease that causes red, itchy scaly patches, most commonly on the knees, elbows, trunk and scalp. Psoriasis is a common, long-term (chronic) disease with no cure. It tends to go through cycles, flaring for a few weeks or months, then subsiding for a while or going into remission
Skin Ailments Psoriasis By Dr. Darbha Aneeta
This is part of the HELP Talk series at HELP,Health Education Library for People, the worlds largest free patient education library www.healthlibrary.com.
Kayakalp is a well-known Skin Care Center for Psoriasis Treatment in Delhi-India with a lot of success records in curing Psoriasis - a challenge for medical community.
http://www.kayakalpglobal.com/psoriasis-treatment-delhi-india.html
Homeopathy treatment offers a long-term cure for Psoriasis. Find common homeopathy medicines which give a remarkable result in the Psoriasis problem. Visit Multicare Homeopathy.
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
Instructions for Submissions thorugh G- Classroom.pptxJheel Barad
This presentation provides a briefing on how to upload submissions and documents in Google Classroom. It was prepared as part of an orientation for new Sainik School in-service teacher trainees. As a training officer, my goal is to ensure that you are comfortable and proficient with this essential tool for managing assignments and fostering student engagement.
Honest Reviews of Tim Han LMA Course Program.pptxtimhan337
Personal development courses are widely available today, with each one promising life-changing outcomes. Tim Han’s Life Mastery Achievers (LMA) Course has drawn a lot of interest. In addition to offering my frank assessment of Success Insider’s LMA Course, this piece examines the course’s effects via a variety of Tim Han LMA course reviews and Success Insider comments.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
The French Revolution, which began in 1789, was a period of radical social and political upheaval in France. It marked the decline of absolute monarchies, the rise of secular and democratic republics, and the eventual rise of Napoleon Bonaparte. This revolutionary period is crucial in understanding the transition from feudalism to modernity in Europe.
For more information, visit-www.vavaclasses.com
A Strategic Approach: GenAI in EducationPeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Synthetic Fiber Construction in lab .pptxPavel ( NSTU)
Synthetic fiber production is a fascinating and complex field that blends chemistry, engineering, and environmental science. By understanding these aspects, students can gain a comprehensive view of synthetic fiber production, its impact on society and the environment, and the potential for future innovations. Synthetic fibers play a crucial role in modern society, impacting various aspects of daily life, industry, and the environment. ynthetic fibers are integral to modern life, offering a range of benefits from cost-effectiveness and versatility to innovative applications and performance characteristics. While they pose environmental challenges, ongoing research and development aim to create more sustainable and eco-friendly alternatives. Understanding the importance of synthetic fibers helps in appreciating their role in the economy, industry, and daily life, while also emphasizing the need for sustainable practices and innovation.
2. PsoriasisPsoriasis is a disease whichis a disease which
affects theaffects the skinskin andand jointsjoints..
It commonly causes red scalyIt commonly causes red scaly
patches to appear on the skin.patches to appear on the skin.
The scaly patches caused byThe scaly patches caused by
psoriasis, called psoriaticpsoriasis, called psoriatic
plaques, are areas ofplaques, are areas of
inflammation and excessiveinflammation and excessive
skin production.skin production.
Skin rapidly accumulates atSkin rapidly accumulates at
these sites and takes a silvery-these sites and takes a silvery-
white appearance.white appearance.
Plaques frequently occur on thePlaques frequently occur on the
skin of the elbows and knees,skin of the elbows and knees,
but can affect any areabut can affect any area
including the scalp and genitals.including the scalp and genitals.
3. Psoriasis is an inflammatory skin disease in which skin cellsPsoriasis is an inflammatory skin disease in which skin cells
replicate at an extremely rapid rate. New skin cells are producedreplicate at an extremely rapid rate. New skin cells are produced
about eight times faster than normal--over several days instead ofabout eight times faster than normal--over several days instead of
a month--but the rate at which old cells slough off is unchanged.a month--but the rate at which old cells slough off is unchanged.
This causes cells to build up on the skin's surface, forming thickThis causes cells to build up on the skin's surface, forming thick
patches, or plaques, of red sores (lesions) covered with flaky,patches, or plaques, of red sores (lesions) covered with flaky,
silvery-white dead skin cells (scales).silvery-white dead skin cells (scales).
4. The disorder is a chronic recurring conditionThe disorder is a chronic recurring condition
which varies in severity from minor localisedwhich varies in severity from minor localised
patches to complete body coverage.patches to complete body coverage.
Fingernails and toenails are frequently affectedFingernails and toenails are frequently affected
(psoriatic nail dystrophy) - and can be seen as an(psoriatic nail dystrophy) - and can be seen as an
isolated finding.isolated finding.
Psoriasis can also cause inflammation of thePsoriasis can also cause inflammation of the
joints, which is known asjoints, which is known as psoriatic arthritispsoriatic arthritis..
5. The cause of psoriasis is not known, but it is believedThe cause of psoriasis is not known, but it is believed
to have a genetic component.to have a genetic component.
Several factors are thought to aggravate psoriasis.Several factors are thought to aggravate psoriasis.
These includeThese include stressstress,, excessive alcohol consumptionexcessive alcohol consumption,,
andand smokingsmoking..
Individuals with psoriasis may suffer from depressionIndividuals with psoriasis may suffer from depression
and loss of self-esteem.and loss of self-esteem.
As such, quality of life is an important factor inAs such, quality of life is an important factor in
evaluating the severity of the disease.evaluating the severity of the disease.
Certain medicines, includingCertain medicines, including lithium saltlithium salt andand
beta blockersbeta blockers, have been reported to trigger or, have been reported to trigger or
aggravate the disease.aggravate the disease.
6. There are two main hypotheses about the process that occurs inThere are two main hypotheses about the process that occurs in
the development of the disease.the development of the disease.
The first considers psoriasis as primarily a disorder of excessiveThe first considers psoriasis as primarily a disorder of excessive
growth and reproduction of skin cells. The problem is simplygrowth and reproduction of skin cells. The problem is simply
seen as a fault of theseen as a fault of the epidermisepidermis and itsand its keratinocyteskeratinocytes..
The second hypothesis sees the disease as being anThe second hypothesis sees the disease as being an
immune-mediated disorderimmune-mediated disorder in which the excessive reproductionin which the excessive reproduction
of skin cells is secondary to factors produced by the immuneof skin cells is secondary to factors produced by the immune
system.system. T cellsT cells (which normally help protect the body against(which normally help protect the body against
infection) become active, migrate to the dermis and trigger theinfection) become active, migrate to the dermis and trigger the
release ofrelease of cytokinescytokines (tumor necrosis factor-alpha TNFα, in(tumor necrosis factor-alpha TNFα, in
particular) which cause inflammation and the rapid productionparticular) which cause inflammation and the rapid production
of skin cells. It is not known what initiates the activation of the Tof skin cells. It is not known what initiates the activation of the T
cells.cells.
The immune-mediated model of psoriasis has been supported byThe immune-mediated model of psoriasis has been supported by
the observation that immunosuppressant medications can clearthe observation that immunosuppressant medications can clear
psoriasis plaques.psoriasis plaques.
7. Plaque psoriasisPlaque psoriasis (psoriasis vulgaris)(psoriasis vulgaris) is theis the
most common form of psoriasis. It affects 80 tomost common form of psoriasis. It affects 80 to
90% of people with psoriasis. Plaque psoriasis90% of people with psoriasis. Plaque psoriasis
typically appears as raised areas of inflamed skintypically appears as raised areas of inflamed skin
covered with silvery white scaly skin. These areascovered with silvery white scaly skin. These areas
are called plaques.are called plaques.
Types of PsoriasisTypes of Psoriasis
8. Flexural psoriasisFlexural psoriasis (inverse(inverse
psoriasis)psoriasis) appears as smoothappears as smooth
inflamed patches of skin. It occursinflamed patches of skin. It occurs
in skin folds, particularly aroundin skin folds, particularly around
the genitals (between the thigh andthe genitals (between the thigh and
groin), the armpits, under angroin), the armpits, under an
overweight stomach (pannus), andoverweight stomach (pannus), and
under the breasts (inframammaryunder the breasts (inframammary
fold). It is aggravated by frictionfold). It is aggravated by friction
and sweat, and is vulnerable toand sweat, and is vulnerable to
fungal infections.fungal infections.
Guttate psoriasisGuttate psoriasis is characterizedis characterized
by numerous small oval (teardrop-by numerous small oval (teardrop-
shaped) spots. These numerousshaped) spots. These numerous
spots of psoriasis appear over largespots of psoriasis appear over large
areas of the body, such as theareas of the body, such as the
trunk, limbs, and scalp. Guttatetrunk, limbs, and scalp. Guttate
psoriasis is associated withpsoriasis is associated with
streptococcal throat infectionstreptococcal throat infection
9. Pustular psoriasisPustular psoriasis appears as raised bumps thatappears as raised bumps that
are filled with non-infectious pus (pustules). Theare filled with non-infectious pus (pustules). The
skin under and surrounding pustules is red andskin under and surrounding pustules is red and
tender. Pustular psoriasis can be localised,tender. Pustular psoriasis can be localised,
commonly to the hands and feet , or generalisedcommonly to the hands and feet , or generalised
with widespread patches occurring randomly onwith widespread patches occurring randomly on
any part of the body.any part of the body.
10. Nail psoriasisNail psoriasis produces a variety of changes inproduces a variety of changes in
the appearance of finger and toe nails. Thesethe appearance of finger and toe nails. These
changes include discolouring under the nailchanges include discolouring under the nail
plate, pitting of the nails, lines going across theplate, pitting of the nails, lines going across the
nails, thickening of the skin under the nail, andnails, thickening of the skin under the nail, and
the loosening (the loosening (onycholysisonycholysis) and crumbling of the) and crumbling of the
nail.nail.
11.
12.
13. Psoriatic arthritisPsoriatic arthritis involvesinvolves
joint and connective tissuejoint and connective tissue
inflammation.inflammation.
Psoriatic arthritis can affectPsoriatic arthritis can affect
any joint but is mostany joint but is most
common in the joints of thecommon in the joints of the
fingers and toes. This canfingers and toes. This can
result in a sausage-shapedresult in a sausage-shaped
swelling of the fingers andswelling of the fingers and
toes known as dactylitis.toes known as dactylitis.
Psoriatic arthritis can alsoPsoriatic arthritis can also
affect the hips, knees andaffect the hips, knees and
spine (spondylitis). About 10-spine (spondylitis). About 10-
15% of people who have15% of people who have
psoriasis also have psoriaticpsoriasis also have psoriatic
arthritis.arthritis.
14. Erythrodermic psoriasisErythrodermic psoriasis
involves the widespreadinvolves the widespread
inflammation and exfoliationinflammation and exfoliation
of the skin over most of theof the skin over most of the
body surface. It may bebody surface. It may be
accompanied by severeaccompanied by severe
itching, swelling and pain.itching, swelling and pain.
It is often the result of anIt is often the result of an
exacerbation of unstableexacerbation of unstable
plaque psoriasis, particularlyplaque psoriasis, particularly
following the abruptfollowing the abrupt
withdrawal of systemicwithdrawal of systemic
treatment. This form oftreatment. This form of
psoriasis can be fatal, as thepsoriasis can be fatal, as the
extreme inflammation andextreme inflammation and
exfoliation disrupt the body'sexfoliation disrupt the body's
ability to regulate temperatureability to regulate temperature
and for the skin to performand for the skin to perform
barrier functions.barrier functions.
15.
16. A diagnosis of psoriasis is usually based on theA diagnosis of psoriasis is usually based on the
appearance of the skin. There are no specialappearance of the skin. There are no special
blood tests or diagnostic procedures forblood tests or diagnostic procedures for
psoriasis. Sometimes a skin biopsy, or scraping,psoriasis. Sometimes a skin biopsy, or scraping,
may be needed to rule out other disorders and tomay be needed to rule out other disorders and to
confirm the diagnosis. Skin from a biopsy willconfirm the diagnosis. Skin from a biopsy will
show clubbed pegs if positive for psoriasis.show clubbed pegs if positive for psoriasis.
Another sign of psoriasis is that when theAnother sign of psoriasis is that when the
plaques are scraped, one can see pinpointplaques are scraped, one can see pinpoint
bleeding from the skin below (Auspitz's sign).bleeding from the skin below (Auspitz's sign).
17. Treatment optionsTreatment options
There can be substantial variation between individualsThere can be substantial variation between individuals
in the effectiveness of specific psoriasis treatments.in the effectiveness of specific psoriasis treatments.
Because of this, dermatologists often use a trial-and-Because of this, dermatologists often use a trial-and-
error approach to finding the most appropriateerror approach to finding the most appropriate
treatment for their patient.treatment for their patient.
The decision to employ a particular treatment is basedThe decision to employ a particular treatment is based
on the type of psoriasis, its location, extent and severity.on the type of psoriasis, its location, extent and severity.
The patient’s age, gender, quality of life, comorbidities,The patient’s age, gender, quality of life, comorbidities,
and attitude toward risks associated with the treatmentand attitude toward risks associated with the treatment
are also taken into consideration.are also taken into consideration.
18. Medications with the least potential for adverseMedications with the least potential for adverse
reactions are preferentially employed.reactions are preferentially employed.
As a first step, medicated ointments or creams areAs a first step, medicated ointments or creams are
applied to the skin. If topical treatment fails to achieveapplied to the skin. If topical treatment fails to achieve
the desired goal then the next step would be to exposethe desired goal then the next step would be to expose
the skin to ultraviolet (UV) radiation. This type ofthe skin to ultraviolet (UV) radiation. This type of
treatment is called phototherapy.treatment is called phototherapy.
The third step involves the use of medications whichThe third step involves the use of medications which
are taken internally by pill or injection : systemicare taken internally by pill or injection : systemic
treatment.treatment.
Over time, psoriasis can become resistant to a specificOver time, psoriasis can become resistant to a specific
therapy. Treatments may be periodically changed totherapy. Treatments may be periodically changed to
prevent resistance developing (tachyphylaxis) and toprevent resistance developing (tachyphylaxis) and to
reduce the chance of adverse reactions occurring:reduce the chance of adverse reactions occurring:
treatment rotation.treatment rotation.
21. Coal TarCoal Tar
- Prefered for limited or scalp psoriasisPrefered for limited or scalp psoriasis
- Can be effective in widespread psoriasisCan be effective in widespread psoriasis
- Antimitotic, anti-pruriticAntimitotic, anti-pruritic
- No quick onset but longer remissionNo quick onset but longer remission
- Often combined with SA, UV light therapyOften combined with SA, UV light therapy
- 2 types: Crude coal tar and Liquor picis carbonis2 types: Crude coal tar and Liquor picis carbonis
22. DithranolDithranol
May restore normal epidermal proliferation andMay restore normal epidermal proliferation and
keratinizationkeratinization
Useful in thick plaque psoriasisUseful in thick plaque psoriasis
Commonly used with SACommonly used with SA
2 treatment approach: long contact and short2 treatment approach: long contact and short
contactcontact
Stains clothes, irritating to normal skinStains clothes, irritating to normal skin
23. Topical CSTopical CS
Anti-inflammatory, immunosuppressiveAnti-inflammatory, immunosuppressive
Quick onset than coal tar and dithranolQuick onset than coal tar and dithranol
Tachyphylaxis can occurTachyphylaxis can occur
High potent agents used in severe cases, thickHigh potent agents used in severe cases, thick
plaquesplaques
AE local and systemicAE local and systemic
Should not be stopped abruptly – reboundShould not be stopped abruptly – rebound
psoriasispsoriasis
24. PhototherapyPhototherapy
UVA, UVB, PUVAUVA, UVB, PUVA
UVB preferedUVB prefered
Administered by lamp, sunlight exposure aloneAdministered by lamp, sunlight exposure alone
or in combo with another topical agentor in combo with another topical agent
PUVA (methoxsalen) given PO 2 hours beforePUVA (methoxsalen) given PO 2 hours before
UVA or lotion applied 30mins before exposureUVA or lotion applied 30mins before exposure
AE: itch, edemaAE: itch, edema
25. Systemic TherapySystemic Therapy
ImmunomodulatorsImmunomodulators
- Cyclosporin, methotrexate commonly usedCyclosporin, methotrexate commonly used
- Antibiotics in case of secondary bacterialAntibiotics in case of secondary bacterial
infectionsinfections
26. Systemic agents are generally recommended forSystemic agents are generally recommended for
patients with moderate-to-severe disease.patients with moderate-to-severe disease.
Moderate disease is defined as greater than 5%Moderate disease is defined as greater than 5%
body-surface area involvement; severe disease isbody-surface area involvement; severe disease is
defined by greater than 10%defined by greater than 10%
27. Psoriasis is a lifelong condition.Psoriasis is a lifelong condition.
There is currently no cure but various treatments canThere is currently no cure but various treatments can
help to control the symptoms. Many of the mosthelp to control the symptoms. Many of the most
effective agents used to treat severe psoriasis carry aneffective agents used to treat severe psoriasis carry an
increased risk of significant morbidity including skinincreased risk of significant morbidity including skin
cancers, lymphoma and liver disease.cancers, lymphoma and liver disease.
Psoriasis does get worse over time but it is not possiblePsoriasis does get worse over time but it is not possible
to predict who will go on to develop extensiveto predict who will go on to develop extensive
psoriasis or those in whom the disease may appear topsoriasis or those in whom the disease may appear to
vanish.vanish.
Individuals will often experience flares and remissionsIndividuals will often experience flares and remissions
throughout their lives. Controlling the signs andthroughout their lives. Controlling the signs and
symptoms typically requires lifelong therapy.symptoms typically requires lifelong therapy.
SummarySummary