Arsenic is a naturally occurring element that can contaminate aquaculture systems and harm fish and humans. It accumulates in fish through their food and water. In aquaculture, arsenic in the water and sediments can build up in fish and cause diseases like black spot disease, reducing fish production. Humans are also at risk if they consume contaminated fish or drink arsenic-laden water, as arsenic exposure has been linked to cancers and other health issues. Treatment methods aim to remove arsenic from water sources or aid detoxification. Further efforts are needed to address arsenic contamination and protect aquatic and human health.