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Mobilizing biosciences for Africa’s development	
  
Harnessing the Genetic Diversity of Goats
to Improve Productivity in Africa	
  
This	
  document	
  is	
  licensed	
  for	
  use	
  under	
  a	
  Crea3ve	
  Commons	
  A6ribu3on-­‐Noncommercial-­‐Share	
  Alike	
  3.0	
  Unported	
  License	
  	
  	
  	
  	
  	
  	
  	
  
May	
  2013	
  
BecA-ILRI Hub, ILRI, University of Dschang	
  
Exploring	
  Eastern	
  and	
  Central	
  African	
  Goat	
  
Gene3c	
  landscape	
  
Goats	
  are	
  extremely	
  diverse	
  in	
  their	
  appearance	
  and	
  the	
  ecosystems	
  they	
  occupy.	
  
We	
  are	
  interroga8ng	
  this	
  diversity	
  at	
  DNA	
  level	
  to	
  a	
  high	
  resolu8on	
  enabled	
  by	
  
modern	
  DNA	
  and	
  geo-­‐spa8al	
  analysis	
  tools.	
  DNA	
  samples	
  collected	
  from	
  goats	
  
adapted	
  to	
  hot	
  humid,	
  cool	
  highlands,	
  or	
  hot	
  dry	
  ecological	
  zones	
  	
  in	
  both	
  
Cameroon	
  and	
  Ethiopia	
  will	
  be	
  studied	
  for	
  	
  genome	
  signatures	
  consistent	
  with	
  
adapta8on	
  to	
  their	
  na8ve	
  biophysical	
  environments.	
  We	
  will	
  also	
  explore	
  the	
  
diversity	
  of	
  African	
  wild	
  ibexes	
  (e.g.	
  Nubian	
  Ibex)	
  and	
  their	
  possible	
  contribu8on	
  to	
  
African	
  domes8c	
  goat	
  gene	
  pool.	
  These	
  analysis	
  will	
  contribute	
  to	
  and	
  benefit	
  from	
  
other	
  goat	
  gene8c	
  diversity	
  studies	
  such	
  as	
  the	
  African	
  Genome	
  improvement	
  
Network	
  (AGIN)	
  and	
  the	
  ADAPTmap.	
  
Figure	
  	
  A:	
  	
  Approximate	
  distribu8on	
  of	
  Ethiopian	
  goat	
  popula8ons	
  based	
  on	
  morphological	
  characters.	
  Details	
  of	
  
special	
  aMributes	
  of	
  each	
  popula8on	
  can	
  be	
  found	
  	
  can	
  be	
  found	
  at	
  DAGRIS:	
  hMp://dagris.ilri.cgiar.org	
  
Breeding	
  for	
  Reproduc3ve	
  Efficiency	
  
Goat	
  produc8on	
  systems	
  that	
  are	
  predominantly	
  geared	
  towards	
  meat	
  produc8on	
  
which	
  necessarily	
  demand	
  high	
  animal	
  turnover	
  and	
  so	
  does	
  that	
  deliver	
  mul8ple	
  
kids	
  are	
  economically	
  desirable.	
  	
  The	
  West	
  African	
  dwarf	
  goats	
  commonly	
  give	
  
birth	
  to	
  three,	
  even	
  four	
  kids	
  per	
  birth	
  (pictured	
  below	
  with	
  four	
  kids)	
  and	
  so	
  they	
  
are	
  a	
  good	
  resource	
  to	
  discover	
  factors	
  that	
  control	
  reproduc8ve	
  efficiency.	
  
High	
  fecundity	
  rate	
  in	
  West	
  African	
  	
  Dwarf	
  goats	
  is	
  may	
  be	
  under	
  gene8c	
  control,	
  as	
  
seen	
  in	
  sheep,	
  and	
  therefore	
  amenable	
  to	
  gene8c	
  interven8on.	
  	
  We	
  will	
  aMempt	
  to	
  
iden8fy	
  the	
  gene8c	
  basis	
  of	
  high	
  fecundity	
  rates	
  in	
  goats	
  and	
  develop	
  DNA	
  marker	
  
systems,	
  or	
  other	
  means,	
  to	
  facilitate	
  its	
  introduc8on	
  in	
  other	
  popula8ons	
  where	
  it	
  
is	
  economically	
  impera8ve.	
  
A	
  typical	
  West	
  African	
  Dwarf	
  doe	
  with	
  four	
  
kids.	
  	
  This	
  picture	
  was	
  taken	
  in	
  a	
  goat	
  market	
  
in	
  Cameroon.	
  The	
  en8re	
  set	
  was	
  bought	
  for	
  
$300.	
  	
  	
  	
  Photo	
  by	
  Felix	
  Meutchieye.	
  
Goats	
  Ma6er	
  
Goats	
  are	
  important	
  but	
  oWen	
  undervalued	
  component	
  of	
  the	
  live	
  stock-­‐mix	
  in	
  the	
  
dominant	
  farming	
  systems	
  in	
  Africa.	
  They	
  are	
  found	
  in	
  the	
  dry	
  lands	
  	
  where	
  they	
  
graze	
  extensively	
  in	
  mixed	
  herds	
  with	
  caMle	
  	
  and	
  or	
  sheep	
  or	
  alone.	
  Goats	
  are	
  also	
  
kept	
  in	
  small	
  tethered	
  flocks	
  in	
  small	
  holder	
  systems	
  in	
  mixed	
  farming.	
  	
  Goats	
  
provide,	
  meat,	
  milk	
  and	
  income.	
  	
  Consequently	
  Goats	
  are	
  an	
  important	
  rung	
  in	
  
climbing	
  ladder	
  for	
  nutri8onal	
  and	
  financial	
  security	
  and	
  liquidity.	
  
	
  
The	
  project	
  aims	
  to	
  use	
  innova8on	
  pla[orm	
  to	
  iden8fy	
  and	
  respond	
  to	
  challenges	
  
in	
  the	
  goat	
  produc8on	
  value	
  chain	
  in	
  Ethiopia	
  and	
  Cameroon.	
  	
  The	
  main	
  focus	
  
being	
  on	
  gene8c	
  improvement,	
  effec8ve	
  management	
  of	
  goat	
  breeding	
  and	
  health	
  
and	
  make	
  the	
  marke8ng	
  of	
  goat	
  products	
  more	
  effec8ve	
  in	
  improving	
  the	
  incomes	
  
of	
  farmers.	
  
Project	
  Focus	
  
The	
  principal	
  research	
  focus	
  of	
  this	
  project	
  is	
  to	
  improve	
  profitability	
  of	
  goats	
  by	
  
promo3ng	
  innova3ons	
  in	
  the	
  goat	
  value	
  chain;	
  promo8ng	
  use	
  of	
  produc3ve	
  and	
  
adapted	
  goat	
  genotypes;	
  and	
  reducing	
  the	
  nega8ve	
  environmental	
  impacts	
  the	
  
rumen	
  handicap.	
  
	
  
	
  
Key	
  research	
  ac3vi3es	
  
1.  Innova8on	
  pla[orm	
  and	
  community	
  based	
  breeding	
  in	
  Cameroon	
  and	
  
Ethiopia	
  
2.  Gene8c	
  characteriza8on	
  of	
  goat	
  popula8ons	
  in	
  central	
  and	
  eastern	
  Africa	
  –	
  
Ethiopia,	
  Cameroon,	
  The	
  Sudan,	
  South	
  Sudan	
  and	
  Tanzania.	
  
3.  Explore	
  the	
  poten8al	
  of	
  African	
  wild	
  ibexes	
  for	
  conserva8on	
  and	
  produc8on.	
  
4.  Decipher	
  the	
  role	
  of	
  rumen	
  microbial	
  diversity	
  and	
  func8on	
  in	
  goat	
  
produc8on	
  efficiency.	
  
	
  
	
  
	
  
	
  
	
  
	
  
	
  
	
  
	
  
	
  
	
  
	
  	
  
Project	
  
Countries	
  
Affiliate	
  
countries	
  
	
  1.	
  Next	
  genera8on	
  on	
  animal	
  breeders	
  –	
  	
  
3	
  PhD	
  and	
  6	
  MSc	
  Students	
  in	
  Ethiopia	
  
and	
  Cameroon.	
  
	
  
2.	
  	
  Gene8c	
  makers	
  to	
  aid	
  breeding,	
  and	
  
biological	
  insight	
  into	
  adap8ve	
  traits	
  and	
  
reproduc8on	
  	
  of	
  goats.	
  
	
  
3.	
  	
  Transforma8ve	
  tools	
  and	
  processes	
  to	
  
that	
  add	
  value	
  to	
  the	
  goat	
  value	
  chain.	
  
	
  Outputs:	
  

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Harnessing the genetic diversity of goats to improve productivity in Africa

  • 1. Mobilizing biosciences for Africa’s development   Harnessing the Genetic Diversity of Goats to Improve Productivity in Africa   This  document  is  licensed  for  use  under  a  Crea3ve  Commons  A6ribu3on-­‐Noncommercial-­‐Share  Alike  3.0  Unported  License                 May  2013   BecA-ILRI Hub, ILRI, University of Dschang   Exploring  Eastern  and  Central  African  Goat   Gene3c  landscape   Goats  are  extremely  diverse  in  their  appearance  and  the  ecosystems  they  occupy.   We  are  interroga8ng  this  diversity  at  DNA  level  to  a  high  resolu8on  enabled  by   modern  DNA  and  geo-­‐spa8al  analysis  tools.  DNA  samples  collected  from  goats   adapted  to  hot  humid,  cool  highlands,  or  hot  dry  ecological  zones    in  both   Cameroon  and  Ethiopia  will  be  studied  for    genome  signatures  consistent  with   adapta8on  to  their  na8ve  biophysical  environments.  We  will  also  explore  the   diversity  of  African  wild  ibexes  (e.g.  Nubian  Ibex)  and  their  possible  contribu8on  to   African  domes8c  goat  gene  pool.  These  analysis  will  contribute  to  and  benefit  from   other  goat  gene8c  diversity  studies  such  as  the  African  Genome  improvement   Network  (AGIN)  and  the  ADAPTmap.   Figure    A:    Approximate  distribu8on  of  Ethiopian  goat  popula8ons  based  on  morphological  characters.  Details  of   special  aMributes  of  each  popula8on  can  be  found    can  be  found  at  DAGRIS:  hMp://dagris.ilri.cgiar.org   Breeding  for  Reproduc3ve  Efficiency   Goat  produc8on  systems  that  are  predominantly  geared  towards  meat  produc8on   which  necessarily  demand  high  animal  turnover  and  so  does  that  deliver  mul8ple   kids  are  economically  desirable.    The  West  African  dwarf  goats  commonly  give   birth  to  three,  even  four  kids  per  birth  (pictured  below  with  four  kids)  and  so  they   are  a  good  resource  to  discover  factors  that  control  reproduc8ve  efficiency.   High  fecundity  rate  in  West  African    Dwarf  goats  is  may  be  under  gene8c  control,  as   seen  in  sheep,  and  therefore  amenable  to  gene8c  interven8on.    We  will  aMempt  to   iden8fy  the  gene8c  basis  of  high  fecundity  rates  in  goats  and  develop  DNA  marker   systems,  or  other  means,  to  facilitate  its  introduc8on  in  other  popula8ons  where  it   is  economically  impera8ve.   A  typical  West  African  Dwarf  doe  with  four   kids.    This  picture  was  taken  in  a  goat  market   in  Cameroon.  The  en8re  set  was  bought  for   $300.        Photo  by  Felix  Meutchieye.   Goats  Ma6er   Goats  are  important  but  oWen  undervalued  component  of  the  live  stock-­‐mix  in  the   dominant  farming  systems  in  Africa.  They  are  found  in  the  dry  lands    where  they   graze  extensively  in  mixed  herds  with  caMle    and  or  sheep  or  alone.  Goats  are  also   kept  in  small  tethered  flocks  in  small  holder  systems  in  mixed  farming.    Goats   provide,  meat,  milk  and  income.    Consequently  Goats  are  an  important  rung  in   climbing  ladder  for  nutri8onal  and  financial  security  and  liquidity.     The  project  aims  to  use  innova8on  pla[orm  to  iden8fy  and  respond  to  challenges   in  the  goat  produc8on  value  chain  in  Ethiopia  and  Cameroon.    The  main  focus   being  on  gene8c  improvement,  effec8ve  management  of  goat  breeding  and  health   and  make  the  marke8ng  of  goat  products  more  effec8ve  in  improving  the  incomes   of  farmers.   Project  Focus   The  principal  research  focus  of  this  project  is  to  improve  profitability  of  goats  by   promo3ng  innova3ons  in  the  goat  value  chain;  promo8ng  use  of  produc3ve  and   adapted  goat  genotypes;  and  reducing  the  nega8ve  environmental  impacts  the   rumen  handicap.       Key  research  ac3vi3es   1.  Innova8on  pla[orm  and  community  based  breeding  in  Cameroon  and   Ethiopia   2.  Gene8c  characteriza8on  of  goat  popula8ons  in  central  and  eastern  Africa  –   Ethiopia,  Cameroon,  The  Sudan,  South  Sudan  and  Tanzania.   3.  Explore  the  poten8al  of  African  wild  ibexes  for  conserva8on  and  produc8on.   4.  Decipher  the  role  of  rumen  microbial  diversity  and  func8on  in  goat   produc8on  efficiency.                             Project   Countries   Affiliate   countries    1.  Next  genera8on  on  animal  breeders  –     3  PhD  and  6  MSc  Students  in  Ethiopia   and  Cameroon.     2.    Gene8c  makers  to  aid  breeding,  and   biological  insight  into  adap8ve  traits  and   reproduc8on    of  goats.     3.    Transforma8ve  tools  and  processes  to   that  add  value  to  the  goat  value  chain.    Outputs: