Antidiabetic Activity Of Plant, Plant show antidiabetic property, Which plant show antidiabetic property, Diabetic.

1. Institute-UniversityInstituteofPharmaSciences
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CHANDIGARH
UNIVERSITY
Discover. Learn. Empower
DEPARTMENT- Pharmacy
Master of Pharmacy (Pharmaceutics)
Presented by : Manoj Dalabehera
Alka Kumari
Shubham Chaudhari
22MPH10010
TOPIC- Antidiabetic Activity of Plants with there Phytoconstituents
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22MPH10041
22MPH10002

2. ANTIDIABETICACTIVITY OF PLANTS
WITH THEIR PHYTOCONSTITUENTS
Introduction
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 Diabetes mellitus is one of the most common and serious chronic disease.
 It is a group of metabolic disorder characterised by a high blood sugar level over a prolonged period of time.
 It is also known as hyperglycaemia.
 Serious long term complication include cardiovascular disease, stroke, chronic kidney disease, foot ulcers,
damage to nerve, damage to the eyes and cognitive impairment
Diabetes is due to either the pancreas not producing enough insulin, or the cells of the body not responding
properly to the insulin produced
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 Insulin is a hormone which is responsible for helping glucose from food get into cells to be used for energy.
 There are three main types of diabetes mellitus:
 Type-1 Diabetes results from failure of the pancreas to produce enough insulin due to loss of beta cells.[2] This
form was previously referred to as "insulin-dependent diabetes mellitus" or "juvenile diabetes".[2] The loss of beta
cells is caused by an autoimmune response.
 Type-2 Diabetes begins with insulin resistance, a condition in which cells fail to respond to insulin properly.[2] As
the disease progresses, a lack of insulin may also develop.[17] This form was previously referred to as "non insulin-
dependent diabetes mellitus" or "adult-onset diabetes“
 Gestational Diabetes is the third main form, and occurs when pregnant women without a previous history of
diabetes develop high blood sugar levels.
 Type 1 diabetes must be managed with insulin injections
 Prevention and treatment of type 2 diabetes involves maintaining a healthy diet, regular physical exercise, a
normal body weight, and avoiding use of tobacco
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PLANTS HAVING ANTIDIBETIC PROPERTY
CONTENT
• Botanical Name- Allium cepa Linn
• Family- Liliaceae
• Local name- Pyaz
• Botanical Name- Cinnamomumzeyla
Nees
• Family- Lauraceae
• Local Name- Dalchini
• Botanical Name- Alo vera toum
• Family- Liliaceae
• Local Name- Gheequar
•Botanical Name- Coariander Sativum
•Family- Umbelliferae
•Local Name- Dhania
•Botanical Name- Artemissia pallens Wall
•Family- Compositae
•Local Name- Davana
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5. PYAZ
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Botanical Name- Allium cepa
Linn
Family- Liliaceae
Local name- Pyaz
 Onion (Allium cepa L.) is one of the recognised medicinal plant known to posseses several medicinal properties including anti diabetic activity.
ONION
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 Sulphoxide amino acid from onion inhibit cholesterol and other lipid synthesis.
This is in keeping with lower incidence of heart attack in east asian population regularly consuming allium cepa in there diet.

6. hania
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•Botanical Name- Coariander
Sativum
•Family- Umbelliferae
•Local Name- Dhania
CORIANDER
 Coriander (Coriandrum sativum L.), which belongs to the Umbeliferae family.
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 It is one of the many plants used as traditional medicines.
 All parts of this plant are edible, but the most commonly used part are the leaves and the seeds
 Used to treat cold, thrush, gastric nflammatory, dizziness, nausea, and irregular menstruation
 Previous study had shown that the ethanol extract of coriander seed (Coriadrum sativum L.) could lower blood sugar level

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ALOE VERA
Botanical Name- Aloe vera toum
Family- Liliaceae
Local Name- Gheequar
 The effect of Aloe vera juice in combination with glibenclamide was investigated in diabetic patients.
 There was no response to glibenclamide alone but Aloe vera juice significantly reduced levels of fasting
blood glucose within two weeks and of triglycerides within four weeks.
 It showed no effect on cholesterol levels and had no toxic effects on kidney or liver function as assessed by
blood chemistry. The results support the use of Aloe vera in the treatment of diabetes.
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CINNAMON
Botanical Name- Cinnamomumzeyla
Family- Lauraceae
Local Name- Dalchini
 Anti-diabetic activity of cinnamic acid, a pure compound from cinnamon.
 The anti-diabetic effect of Cinnamomi cassiae extract (Cinnamon bark: Lauraceae) in a type
II diabetic was studied.
 Cinnamon extract was administered at different dosages (50, 100, 150 and 200 mg/kg) for 6
weeks.
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ARTEMISIA
•Botanical Name- Artemissia
pallens Wall
•Family- Compositae
•Local Name- Davana
 Artemisia species have been extensively used for the management of diabetes.
 The antidiabetic effect of single or multiple doses of aqueous and alcoholic extracts of Artemisia species was
due to the active compounds of these plants and they all are effective in lessening the blood glucose level
 Oral administration of an aqueous extract (0.39 g/kg) of the aerial parts of this plant produce Hypoglycemic
activity.
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CONCLUSION
 Herbal treatments for diabetes have been used in patients with insulin dependent and non insulin dependent
diabetes.
 There are various plant known for there anti diabetic activity and there scientific validation has also done.
 The reason behind doing this study is to focus on the various phytoconstituents present in the plant having anti
diabetic activity.
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11. REFERENCES
 Kumar GR and Reddy KP: Antidiabetic and antioxidant effect of S-methyl cysteine sulfoxide isolated from onion.
 Chithra P, Sajithalal GB and Chandrakasan G: Influence of Aloe Vera on the healing of dermal wounds anti diabetic
 PushparajP, Tan CH and Tan BK: The mechanism of hypoglycemic action
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