Cancer is the uncontrolled growth of cells that can spread to other tissues. It is a major global health problem, with over 10 million new cases and 6 million deaths each year. The most common cancers worldwide are lung, breast, and colorectal cancers. Treatment options include surgery, radiation therapy, chemotherapy, immunotherapy, and biological therapy. These treatments can cause side effects like hair loss, nausea, vomiting, and reduced immune function. Turmeric contains curcumin, which has shown anti-cancer properties in pre-clinical and clinical studies. Curcumin can prevent cancer cell growth and has shown promise in preventing and treating various cancers like colon, breast, and brain cancers based on its antioxidant and anti-inflammatory properties. Further
Curcumin, the compound responsible for the yellow color of turmeric has much more to offer than just its color. Curcumin comes with a plethora of health benefits which makes it a hot topic in the nutraceutical industry. Unleash the world of curcumin and see the reasons why you need to spice it up!
HALDI BIOLOGICALLY KNOWN AS CURCUMA LONGA AND COMMONLY TURMERIC ITS PHARMACOGNOSY IS DISCUSSED HERE ALSO WHERE IT IS GROW AT HIGHER AND ITS MEDICINAL USES AND FORMULATION AVAILABLE IN MARKET.
Curcumin, the compound responsible for the yellow color of turmeric has much more to offer than just its color. Curcumin comes with a plethora of health benefits which makes it a hot topic in the nutraceutical industry. Unleash the world of curcumin and see the reasons why you need to spice it up!
HALDI BIOLOGICALLY KNOWN AS CURCUMA LONGA AND COMMONLY TURMERIC ITS PHARMACOGNOSY IS DISCUSSED HERE ALSO WHERE IT IS GROW AT HIGHER AND ITS MEDICINAL USES AND FORMULATION AVAILABLE IN MARKET.
What gives carrot & tomato their red color? What is responsible for the yellow color of papaya & mango. This presentation unlocks the secret behind these facts. Enjoy your journey to the colorful world of CAROTENOIDS.
Moringa is used for “tired blood” (anemia); arthritis and other joint pain
(rheumatism); asthma; cancer; constipation; diabetes; diarrhea; epilepsy;
stomach pain; stomach and intestinal ulcers; intestinal spasms; headache; heart
problems; high blood pressure; kidney stones; fluid retention; thyroid disorders;
and bacterial, fungal, viral, and parasitic infections.
Oil from moringa seeds is used in foods, perfume, and hair care products, and as a
machine.
Cancer is one of the fatal disease that has no known complete cure.One of approach in developing the novel drug is through unraveling the enigma of marine biodiversity.
Igennus are excited to announce the launch of our new product, Longvida® Curcumin. During this webinar, Dr Bailey reviews the research behind the therapeutic use of curcumin and why Longvida is the world’s most advanced formulation of the nutrient.
Curcumin is a polyphenol compound obtained from the rhizome of Curcuma longa, also known as turmeric. This Indian spice has a long history of use in Ayurvedic medicine as a treatment for inflammatory conditions. Curcumin is well documented for its antioxidant, anti-inflammatory and anti-cancer activities. Although it has been shown to be safe at high doses (12g/d), it is poorly absorbed, undergoes rapid intestinal and hepatic metabolism and is rapidly eliminated from the body. As such, standard curcumin demonstrates poor bioavailability, even at high doses, limiting its therapeutic potential.
After much research and discussion (it’s a big and complicated topic!) between the Igennus nutrition scientists, the decision as to which type of curcumin we would use for our Synergistic Nutrients range was actually a very straightforward one. Longvida Curcumin utilises a novel delivery system (SLCP), which protects curcumin from the harsh environment of the stomach and promotes its rapid absorption into the bloodstream and target tissues, even at low doses – resulting in an incredible 285x superior bioavaibility compared with standard curcumin, 65x higher peak plasma levels and 7x longer-lasting action. Longvida is the only formulation proven to deliver high levels of free form, unconjugated curcumin, into the bloodstream. Free form curcumin is the form required for therapeutic benefits, and the only form proven to cross the blood brain barrier.
This webinar covers:
- What curcumin is, what it does and how?
- Why free form curcumin is essential for therapeutic effects
- The research and current evidence for Longvida Curcumin’s unique health benefits
- How Longvida overcomes significant bioavailability issues associated with curcumin use
- To who, why and when you should recommend curcumin
…and more.
BREAST CANCER DRUG DISCOVERY & RESEARCH FROM VARIOUS WELL KNOWN ETHNOMEDICINAL PLANTS. ESTABLISHED PHYTOMOLECULES WITH CHEMOPREVENTIVE, ANTICANCER ACTIVITIES WITH MINIMAL TOXICITY.
What gives carrot & tomato their red color? What is responsible for the yellow color of papaya & mango. This presentation unlocks the secret behind these facts. Enjoy your journey to the colorful world of CAROTENOIDS.
Moringa is used for “tired blood” (anemia); arthritis and other joint pain
(rheumatism); asthma; cancer; constipation; diabetes; diarrhea; epilepsy;
stomach pain; stomach and intestinal ulcers; intestinal spasms; headache; heart
problems; high blood pressure; kidney stones; fluid retention; thyroid disorders;
and bacterial, fungal, viral, and parasitic infections.
Oil from moringa seeds is used in foods, perfume, and hair care products, and as a
machine.
Cancer is one of the fatal disease that has no known complete cure.One of approach in developing the novel drug is through unraveling the enigma of marine biodiversity.
Igennus are excited to announce the launch of our new product, Longvida® Curcumin. During this webinar, Dr Bailey reviews the research behind the therapeutic use of curcumin and why Longvida is the world’s most advanced formulation of the nutrient.
Curcumin is a polyphenol compound obtained from the rhizome of Curcuma longa, also known as turmeric. This Indian spice has a long history of use in Ayurvedic medicine as a treatment for inflammatory conditions. Curcumin is well documented for its antioxidant, anti-inflammatory and anti-cancer activities. Although it has been shown to be safe at high doses (12g/d), it is poorly absorbed, undergoes rapid intestinal and hepatic metabolism and is rapidly eliminated from the body. As such, standard curcumin demonstrates poor bioavailability, even at high doses, limiting its therapeutic potential.
After much research and discussion (it’s a big and complicated topic!) between the Igennus nutrition scientists, the decision as to which type of curcumin we would use for our Synergistic Nutrients range was actually a very straightforward one. Longvida Curcumin utilises a novel delivery system (SLCP), which protects curcumin from the harsh environment of the stomach and promotes its rapid absorption into the bloodstream and target tissues, even at low doses – resulting in an incredible 285x superior bioavaibility compared with standard curcumin, 65x higher peak plasma levels and 7x longer-lasting action. Longvida is the only formulation proven to deliver high levels of free form, unconjugated curcumin, into the bloodstream. Free form curcumin is the form required for therapeutic benefits, and the only form proven to cross the blood brain barrier.
This webinar covers:
- What curcumin is, what it does and how?
- Why free form curcumin is essential for therapeutic effects
- The research and current evidence for Longvida Curcumin’s unique health benefits
- How Longvida overcomes significant bioavailability issues associated with curcumin use
- To who, why and when you should recommend curcumin
…and more.
BREAST CANCER DRUG DISCOVERY & RESEARCH FROM VARIOUS WELL KNOWN ETHNOMEDICINAL PLANTS. ESTABLISHED PHYTOMOLECULES WITH CHEMOPREVENTIVE, ANTICANCER ACTIVITIES WITH MINIMAL TOXICITY.
Excellent presentation on cancer
A book written by Professor Richard Beliveau and Dr Denis Ginger on “foods to fight cancer” have the following findings:
Statistic shows that one out of three people is affected by cancer before the age of 75
This represents 12 per cent of all reported deaths on Earth.
However, fear not, there is hope.
Cancer- Types, Pathophysiology, Epidemiology, Management, Available Drugs, MOA, Total Market, Limitations of presently available drugs, brand names of available brands with their company name
Herbal remedies for cancer such as those commonly found in Thai traditional medicine contain antimutagenic, anti-inflammatory, and apoptosis-inducing compounds that help in slowing the development of cancer.
This is a presentation which was sent to me by a friend. Being a topic which remains a perennial cause of concern I felt that I should share it with everyone - hence this upload.
Welcome to TechSoup New Member Orientation and Q&A (May 2024).pdfTechSoup
In this webinar you will learn how your organization can access TechSoup's wide variety of product discount and donation programs. From hardware to software, we'll give you a tour of the tools available to help your nonprofit with productivity, collaboration, financial management, donor tracking, security, and more.
Safalta Digital marketing institute in Noida, provide complete applications that encompass a huge range of virtual advertising and marketing additives, which includes search engine optimization, virtual communication advertising, pay-per-click on marketing, content material advertising, internet analytics, and greater. These university courses are designed for students who possess a comprehensive understanding of virtual marketing strategies and attributes.Safalta Digital Marketing Institute in Noida is a first choice for young individuals or students who are looking to start their careers in the field of digital advertising. The institute gives specialized courses designed and certification.
for beginners, providing thorough training in areas such as SEO, digital communication marketing, and PPC training in Noida. After finishing the program, students receive the certifications recognised by top different universitie, setting a strong foundation for a successful career in digital marketing.
How to Make a Field invisible in Odoo 17Celine George
It is possible to hide or invisible some fields in odoo. Commonly using “invisible” attribute in the field definition to invisible the fields. This slide will show how to make a field invisible in odoo 17.
Embracing GenAI - A Strategic ImperativePeter Windle
Artificial Intelligence (AI) technologies such as Generative AI, Image Generators and Large Language Models have had a dramatic impact on teaching, learning and assessment over the past 18 months. The most immediate threat AI posed was to Academic Integrity with Higher Education Institutes (HEIs) focusing their efforts on combating the use of GenAI in assessment. Guidelines were developed for staff and students, policies put in place too. Innovative educators have forged paths in the use of Generative AI for teaching, learning and assessments leading to pockets of transformation springing up across HEIs, often with little or no top-down guidance, support or direction.
This Gasta posits a strategic approach to integrating AI into HEIs to prepare staff, students and the curriculum for an evolving world and workplace. We will highlight the advantages of working with these technologies beyond the realm of teaching, learning and assessment by considering prompt engineering skills, industry impact, curriculum changes, and the need for staff upskilling. In contrast, not engaging strategically with Generative AI poses risks, including falling behind peers, missed opportunities and failing to ensure our graduates remain employable. The rapid evolution of AI technologies necessitates a proactive and strategic approach if we are to remain relevant.
Model Attribute Check Company Auto PropertyCeline George
In Odoo, the multi-company feature allows you to manage multiple companies within a single Odoo database instance. Each company can have its own configurations while still sharing common resources such as products, customers, and suppliers.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
Acetabularia Information For Class 9 .docxvaibhavrinwa19
Acetabularia acetabulum is a single-celled green alga that in its vegetative state is morphologically differentiated into a basal rhizoid and an axially elongated stalk, which bears whorls of branching hairs. The single diploid nucleus resides in the rhizoid.
2. Presented by:
Debolina Kundu
Sem : 7th Year : 4th
University Roll no: 20101916054
Registration no: 162010210015 of 2016-2017
Guidance by :
Dr.Nityananda Mondal
Associate Professor
B.C.D.A. College Of Pharmacy & Technology
3. cancer
• Cancer is commonly defined as the uncontrolled growth of cells, with loss
of differentiation and commonly, with metastasis, spread of the cancer to
other tissues and organs.
• Cancers are malignant growths.
4. Cancer problem statement
• Worldwide
Every year 10 million people are diagnosed and more then 6 million
die
22.4 million peoples were living with cancer in 2000
• Most common cancer worldwide are
Lungs cancer (12.3%)
Breast cancer (10.4%)
Colorectal cancer (9.4%)
5. Treatment
• In localized cancer surgery typicall attempts to
remove the entire mass.
• Biological therapy/immunotherapy
• Monoclonal antibodies, interferon, interleukin-
2, and colony-stimulating factors.
surgery
• High-energy rays are used to kill cancer cells
• Stop them from growing and dividing.
• radiotherapy is a local treatment; it can affect cancer
cells only in the treated area.
Radiation
therapy
• Drugs used to kill cancer cells; disrupt some aspect
of cell division.
• Toxic to healthy cells; hair, bone marrow,
lymphocytes, and epithelial cells of intestinal lining .
chemotherapy
6. Side effects of anticancer therapy
Chemotherapy
Radiation
therapy
Surgery
therapy
• hair loss
• nausea
• Vomiting
• reduced immune responses
• Tiredness,
• skin reactions such as rash or
redness, and loss of appetite.
• Temporary lowering of the
WBC count
• Temporary flu-like symptoms
such as fever and chills,
muscle aches and weakness,
loss of appetite and diarrhea
7. Turmeric
• Turmeric is the ancient and sacred spice of India known as ‘Indian saffron’
is an important commercial spice crop grown in India.
• Turmeric has been used extensively in Ayurvedic medicine for centuries
• It has anti cancer property.
• Curcumin is a major biological active compound that prevent cancer cell
growth.
8. Biological source
Turmeric consists of dried as well as fresh rhizomes of the plant known as
curcuma longa Linn(C.domestica).
family: Zingiberaceae
10. Geographical source
• The plant is a native to southern Asia and is cultivated extensively in
temperate regions.
• It is grown on a larger scale in India, China, East Indies and Pakistan
11. Macroscopic character
• Externally , the drug is yellowish-brown in colour with characteristic odour
and slightly bitter taste.
• Round turmeric rhizomes are oblong, while long variety is cylindrical and
short branched.
• Root scars and annulations are present.
• The fracture is horny and internal surface is orange.
• Rhizomes are 5 to 10 × 2 to 4 cm. in size.
12. Microscopic character
• 4 to 6 layers of brick shaped parenchymatous cork
• The cortex consists of thin walled rounded
parenchymatous cells containing scattered
vascular bundles.
• Oleo resin cells: brownish
suberised cell walls
• Vascular bundle present in cortex.
• Vascular bundle in pith region
forming endodermis
• Starch grains abundant.
15. Cancer prevention
• Neutralizes substances and conditions that cause cancer.
• Helps cells retain integrity if infected by carcinogen.
• Curcumin can destroy tumor growth.
• Possibly inhibits synthesis of protein that causes tumor growth and
preventing development of additional blood supply necessary for cell
growth.
• Tumors of esophagus, mouth, intestines, stomach, breast and skin
• In animal testing, cancer growth is slowed, inhibited and mass
reduced
• Natural COX-2 inhibitor3
– Block an enzyme called cyclooxygenase-2. This is beneficial because
the COX-2 enzyme
– helps make carcinogens more active in the body and allows cancerous
cells to survive by growing new blood vessels.
• Colon cells protected from free radical that damage DNA because of
curcumin's antioxidant actions.
16. Types of cancer that prevent
curcumin
• Colon cancer
• Rectal cancer
• Pancreatic cancer
• Osteosarcoma
• Melanoma
• Brain tumors
• Breast cancer
17. Clinical trials
condition sites intervention Trial phase Completion
date
Colon cancer
prevention
University of
pennsylvania
Curcuminoid
complex, 4g daily
Phase II June 2009
Rectal cancer MD Anderson
cancer centre
Curcumin, 4g
daily
Phase II July 2010
Panceratic cancer MD Anderson
cancer centre
Curcumin, 8g
daily
Phase II December 2009
osteosarcoma Tata Memorial
Hospital
Curcumin and
ashwaganda
Phase I and II May 2012
18. SAFETY AND TOXICOLOGY
Pregnancy and lactation
While studies in pregnant rats, mice, guinea pigs, and monkeys
suggested that the use of turmeric or curcumin is safe for those
animals in pregnancy, there have been no studies involving pregnant
women subjects reported to date.
Based on studies on possible interactions of turmeric with other herbs or
medicines, it can be advised that turmeric (or curcumin supplements)
should not be used in the following
1. People who are on blood thinning medications, e.g., warfarin,
aspirin, etc.
2. People who are on nonsteroidal anti-inflammatory drugs, e.g.,
indomethacin, ibuprofen, etc.
3. People who are on the hypotensive drug, reserpine.
19. DOSAGE
Turmeric as a spice
can also be
incorporated into the
diet as way to
promote health.
Many people take
400-600 mg. of
turmeric three times
per day in capsules or
tablets
21. Conclusions
• Accumulating preclinical studies have shown that curcumin can interfere
with an increasing number of molecular targets, pathways and processes
involved in cancer.
• As a natural product, curcumin is both non-toxic as well as diversified in its
inhibitory effects involved in carcinogenesis and tumor formation.
22. Reference
• Aggarwal BB, Kumar A, Bharti AC. Anticancer potential of curcumin: preclinical and
clinical studies. Anticancer Res. 2003;23:363–398
• Ammon HP, Wahl MA. Pharmacology of Curcuma longa. Planta Med. 1991;57:1–7.
doi: 10.1055/s-2006-960004.
• Chattopadhyay I, Biswas K, Bandyopadhyay U, Banerjee RK. Turmeric and
curcuminBiological actions and medicinal applications. Curr Sci. 2004;87:44–50
• C.K.Kokate; A.P.Purohit; S.B.Gokhale. pharmacognosy( 14.132-14.134)
• K.D. Tripathi .Essentials Medical Pharmacology, fifth edition (769-782)
• Hsu CH, Cheng AL, Clinical studies with curcumin: Adv Exp Med Biol 595: 471-
480, 2007
• Agrawal DK, Mishra PK,Curcumin and its analogs: potential anti-cancer
agents. Med Res Rev 30: 818-860, 2010.