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Year wise total cancer prevalence in India [ICMR, 2006; ICMR, 2009]](https://image.slidesharecdn.com/presentationoncancer-140809230658-phpapp02/85/Presentation-on-cancer-13-320.jpg)
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Presentation on cancer
This document discusses cancer, including types, causes, epidemiology, management, and prevention. It notes that lung, breast, colon, rectal, endometrial, pancreatic, kidney, prostate, thyroid, and leukemia are common cancer types. Environmental factors like tobacco, alcohol, diet, occupation, viruses, parasites, and lifestyle habits contribute to cancer risk. Genetic factors can also play a role. The global cancer burden is expected to increase, with more deaths in developing countries by 2020. Cancer rates vary between developed and developing economies and within India based on etiological factors like smoking, betel nut chewing, and air pollution. Lifestyle changes, physical activity, and healthy diets can help prevent cancer. Recent studies found
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Presentation on cancer
- 1. CANCER Shantanu Sen Product Specialist TheHimalaya Drug Company
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- 4. TYPES OF CANCER •lung cancer • Breast cancer • Colon and rectal cancer • Endometrial cancer • Pancreatic cancer • Kidney cancer • Prostrate cancer • Thyroid cancer • leukemia
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- 8. Environmental factors • Tobacco •Alcohol • Dietary Factors • Occupational exposures • Viruses • Parasites • Customs ,habits, Lifestyles • Others – sunlight, pollution, drugs Genetic Eg • Retinoblastoma in Children • Leukemia in Mongols CAUSES OF CANCER
- 9. Factors Believed toContribute to Global Causes of Cancer
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- 12. CANCER CAUSES INDEVELOPED AND DEVELOPING ECONOMIES
- 13. Cancer scenario inIndia Year wise total cancer prevalence in India [ICMR, 2006; ICMR, 2009]
- 14. ETIOLOGICAL FACTORS FORDIFFERENT CANCERS IN INDIA SMOKING & HOOKAH BIDI & HOOKAH SMOKING SMOKED MEAT,TOBACCO, HOOKAH BETEL NUT, PANMASALA, ALCOHOL BETEL CHEWING PAN MASALAAND ALCOHOL NUCLEAR POLLUTION AIR POLLUTION PAN MASALA & GUTKA Etiological factors for the prevalence of different cancers in India [Koul et al, 2010; ICMR, 2001; Somdatta et al, 2008; Sharma et al, 2009; Gaur et al, 2006; Prasad et al, 2005; Malothu et al, 2010; Sumathi et al, 2009; (b): http// TOBACCO USE IN DIFFERENT FORM TUIBUR GALL STONES
- 15. COMPARISON OF CANCER INDIAWITH GLOBAL SCENARIO • 2020- 10 million deaths,70% in developing countries ( Murray et al,1996) • Incidence in India less than developed countries (Fenley et al ,2001) • Lung cancer worldwide 14%,all of india 6.8%(Nandakumar,2001) • South east asian countries including India, lower rates of stomach cancer (Parkin et al,1999,WHO,2001),mizoram shows increased no cases ( Hadjiiski et al, 2006)
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- 17. Management Of Cancer •Surgery • Radiotherapy • Chemotherapy • Immunotherapy • Hormone therapy • Gene therapy • Cancer-specific immune system cells to treat cancer
- 18. Preventive measures ofcancer o physical activities o avoiding obesities o healthy dietary practices o reducing occupational and environmental exposures o reducing alcohol uses o immunization against hepatitis B virus o safe sexual practices for avoiding cancer genesis
- 19. RECENT STUDIES • Lifestylechanges reduce the risk of prostate cancer( published in the journal Nutrition and Cancer, was carried out by researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC).) • Researchers Aiming To Suppress Therapy Resistance In Brain Cancer (http://www.medicalnewstoday.com/releases/262571.php) • Fish Oils Reduce Risk Of Breast Cancer (http://www.medicalnewstoday.com/articles/262612.php)
- 20. Life style changesreduce the risk of prostate cancer (Nutrition and Cancer" Lenore Arab, PhD, et al. Nutrition and Cancer Jun-2013) • Focuses on 8 new lifestyle recommendation by WCRF • Encouraged physical activity and consumption of food low in caloric density(under 125kcal/100 grams of food) • who followed less than 4 recommendation at higher risk(38%)
- 21. Research aiming tosuppress therapy resistance in brain cancer (Helmholtz Association of German Research Centres. Medical News Today. MediLexicon, Intl., 29 Jun. 2013. Web) • Gliomas are malignant brain tumors, treatment combines radiotherapy with anticancer drug temozolomide • Some cases shows resistance , DNA repair mechanism aided by NAD+ molecule • QRTP enzyme break down quinolinic acid to NAD+ molecule • Agent directed against enzyme help suppress therapy resistance in brain
- 22. Fish oil reducesthe risk of breast cancer (Nordqvist, Joseph. "Fish Oils Reduce Risk Of Breast Cancer." Medical News Today. MediLexicon, Intl., 28 Jun. 2013. Web.) • Links fish,n-3PUFA intake and risk of breast cancer • Marine n-3PUFA intake associated with 14% reduced risk of breast cancer • For every 0.1g/day increase in consumption ,risk reduced by 5%
- 23. Anticancer Drugs WithTheir MOA
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- 25. Limitations Of PresentlyAvailable Drugs • Myelotoxicity • Alopecia • loss of appetite & weight • nausea & vomitus • taste change • stomatitis, esophagitis, constipation, diarrhea •Cardiotoxicity •Neurotoxicity •lung damage •sterility & teratogenicity •hepatotoxicity & nefrotoxicity •↓ wound healing •↓ growth (children) •carcinogenicity
- 26. Anticancer Drugs InThe Market
- 27. Market share ofAnticancer Drug Makers
- 28. Growth In CancerMarket
- 29. REFERENCE • All aboutcancer http://www.medicalnewstoday.com/info/cancer-oncology/ • Imran Ali,Waseem A. Wani and Kishwar Saleem,( 2011)Cancer Scenario in India with Future Perspectives, Cancer Therapy Vol 8, 56-70 • National cancer institute, http://www.cancer.gov/ • Gobal cancer facts and figures, http://www.cancer.org/acs/groups/content/@epidemiology surveilance/documents/document/acspc-027766.pdf
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