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Anthrax
Created by Danny Mills
Anthrax

• Anthrax is a bacteria
• Bacillus anthracis
• Comes in Two forms
  – Vegetative, spore
• Reproduce by asexual fission and
sporulation
Spore Form

• Spores occur when:
  – Poor nutrient conditions
  – Presence of oxygen

  – Very resistant
  – Survive for decades
News Reports
Primary Hosts

• The primary hosts of Anthrax
warm blooded animals such as:
Humans
Cattle
Sheep
Ways Humans can Get it

• Cutaneous (Skin)
  – Contact with infected
    tissues or animal fibers
• Inhalational
  – Tanning hides,
    processing wool or bone
• Gastrointestinal
  – Undercooked meat
Where Humans can get it


• Tanneries
• Textile mills
• Slaughterhouses
Anthrax Around the World




    Anywhere from 30,000 to 100,000
Cutaneous (Skin) Anthrax

•   A form of Anthrax -
•   95% of all cases
•   Incubation: 2 to 3 days
•   Spores enter skin through open wound
•   Skin infection begins as a raised itchy bump
Gastrointestinal Anthrax

• Incubation: 2 to 5 days
• Case fatality rate: 25 to 75%
• has not been documented in
  U.S.
• nausea, loss of appetite, vomiting, fever
  followed by abdominal pain and vomiting of
  blood
Inhalational Anthrax

• Incubation: 1 to 7 days
• Usually Fatal
• resemble a common cold – sore throat, mild
  fever, muscle aches and malaise
• Then severe breathing problems and shock
History of Anthrax
• United States 2001 – Postal Services
  – 13 reported cases
• The largest reported food-borne epidemic
  was in Zimbabwe, in the 1970s.
  – From eating animals that died of Anthrax
Ways to Treat it

• Ciprofloxacin, doxycycline and penicillin
• Course of treatment: 60 days
Prevention

• Humans protected by preventing disease in
  animals
• Safety practices in laboratories
Vaccination

• People who are at risk include
  – Livestock handlers
  – Military personnel
• Vaccine/Immunity Shots
  – Five injections over 18-week period
Interesting Facts (Bioterrorism)
• 100 lbs of spores
  – Urban area of 5 million
  – Estimated impact
     • 250,000 cases of anthrax
     • 100,000 deaths
• 220 lbs of spores
  – Upwind of Wash D.C.
  – Estimated impact
     • 130,000 to 3 million deaths
Some Interesting Facts

• Thousands of anthrax spores are required for
  human infection, of which all can fit in the
  area of a single pinhead.
• Anthrax is a seasonal disease that is controlled
  by temperature fluctuations, amount of rain
  received, and soil type.
• 143 nations around the world have signed a
  treaty banning the use of weapons loaded
  with anthrax spores.
http://vetmed.iastate.edu/vdpam/new-vdpam-employees/food-
supply-veterinary-medicine/swine/swine-diseases/anthrax-0
http://www.cfsph.iastate.edu/Factsheets/pdfs/anthrax.pdf
http://www.cfsph.iastate.edu/FastFacts/pdfs/anthrax_F.pdf
http://www.cfsph.iastate.edu/DiseaseInfo/notes/Anthrax.pdf
http://www.pbs.org/wgbh/nova/military/keim-anthrax.html
http://www.vetmed.lsu.edu/whocc/mp_world.htm
http://chestjournal.chestpubs.org/content/116/5/1369.long
http://www.bt.cdc.gov/agent/anthrax/faq/signs.asp
http://www.ph.ucla.edu/epi/bioter/detect/antdetect_intro.html
http://bioweb.uwlax.edu/bio203/s2008/cottor_mick/index_files/Page
969.htm

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Anthrax