Efficiency of newer generation edge wise applience /certified fixed orthodont...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Computer Navigated Medial Opening Wedge High Tibial Osteotomy- Review of Lite...CrimsonPublishersOPROJ
Computer Navigated Medial Opening Wedge High Tibial Osteotomy- Review of Literature by Kunal Dhurve* in Crimson Publishers: Orthopedic Research and Reviews Journal
Short term and long-term stability of surgically assisted rapid palatal expan...Dr Sylvain Chamberland
Introduction: The purpose of this article is to present further longitudinal data for short-term and long-term
stability, following up our previous article in the surgery literature with a larger sample and 2 years of stability
data. Methods: Data from 38 patients enrolled in this prospective study were collected before treatment, at maximum
expansion, at removal of the expander 6 months later, before any second surgical phase, at the end of
orthodontic treatment, and at the 2-year follow-up, by using posteroanterior cephalograms and dental casts.
Results: With surgically assisted rapid palatal expansion (SARPE), the mean maximum expansion at the first
molar was 7.60 6 1.57 mm, and the mean relapse was 1.83 6 1.83 mm (24%). Modest relapse after completion
of treatment was not statistically significant for all teeth except for the maxillary first molar (0.99 6 1.1 mm). A
significant relationship (P-.0001) was observed between the amount of relapse after SARPE and the posttreatment
observation. At maximum, a skeletal expansion of 3.58 6 1.63 mm was obtained, and this was stable.
Conclusions: Skeletal changes with SARPE were modest but stable. Relapse in dental expansion was almost
totally attributed to lingual movement of the posterior teeth; 64% of the patients had more than 2 mm of dental
changes. Phase 2 surgery did not affect dental relapse.
Efficiency of newer generation edge wise applience /certified fixed orthodont...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Computer Navigated Medial Opening Wedge High Tibial Osteotomy- Review of Lite...CrimsonPublishersOPROJ
Computer Navigated Medial Opening Wedge High Tibial Osteotomy- Review of Literature by Kunal Dhurve* in Crimson Publishers: Orthopedic Research and Reviews Journal
Short term and long-term stability of surgically assisted rapid palatal expan...Dr Sylvain Chamberland
Introduction: The purpose of this article is to present further longitudinal data for short-term and long-term
stability, following up our previous article in the surgery literature with a larger sample and 2 years of stability
data. Methods: Data from 38 patients enrolled in this prospective study were collected before treatment, at maximum
expansion, at removal of the expander 6 months later, before any second surgical phase, at the end of
orthodontic treatment, and at the 2-year follow-up, by using posteroanterior cephalograms and dental casts.
Results: With surgically assisted rapid palatal expansion (SARPE), the mean maximum expansion at the first
molar was 7.60 6 1.57 mm, and the mean relapse was 1.83 6 1.83 mm (24%). Modest relapse after completion
of treatment was not statistically significant for all teeth except for the maxillary first molar (0.99 6 1.1 mm). A
significant relationship (P-.0001) was observed between the amount of relapse after SARPE and the posttreatment
observation. At maximum, a skeletal expansion of 3.58 6 1.63 mm was obtained, and this was stable.
Conclusions: Skeletal changes with SARPE were modest but stable. Relapse in dental expansion was almost
totally attributed to lingual movement of the posterior teeth; 64% of the patients had more than 2 mm of dental
changes. Phase 2 surgery did not affect dental relapse.
Functional outcome of Arthroscopic reconstruction of single bundle anterior c...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Mandibular arch form the relationship between dental and basal anatomyEdwardHAngle
We investigated mandibular dental arch form at the levels of both the clinically relevant application points of the orthodontic bracket and the underlying anatomic structure of the apical base. The correlation of both forms was evaluated and examined to determine whether the basal arch could be used to derive a standardized clinical arch form.
Transverse growth of the maxilla and mandible in untreated girls with low, av...EdwardHAngle
The purpose of this study was to investigate maxillary and mandibular transverse growth in
untreated female subjects with low, average, and high mandibular plane angles longitudinally from ages 6 to 18.
Purpose: To assess the amount of dental and skeletal expansion and stability after surgically assisted
rapid maxillary expansion (SARPE).
Patients and Methods: Data from 20 patients enrolled in this prospective study were collected before
treatment, at maximum expansion, at the removal of the expander 6 months later, before any second
surgical phase, and at the end of orthodontic treatment, using posteroanterior cephalograms and dental
casts.
Results: With SARPE, the mean maximum expansion at the first molar was 7.48 1.39 mm, and the
mean relapse during postsurgical orthodontics was 2.22 1.39 mm (30%). At maximum, a 3.49 1.37
mm skeletal expansion was obtained, and this expansion was stable, such that the average net expansion
was 67% skeletal.
Conclusion: Clinicians should anticipate a loss of about one third of the transverse dental expansion
obtained with SARPE, although the skeletal expansion is quite stable. The amount of postsurgical relapse
with SARPE appears quite similar to the changes in dental-arch dimensions after nonsurgical rapid palatal
expansion, and also quite similar to dental-arch changes after segmental maxillary osteotomy for
expansion.
Effects of rapid palatal expansion on the sagittal and vertical dimensions of...EdwardHAngle
The purpose of this study was to use cone-beam computed tomography imaging to examine the skeletal and dental changes in the sagittal and vertical dimensions after rapid palatal expansion.
Subjective classification and objective analysis of the mandibular dental arc...EdwardHAngle
Our objective was to evaluate the relationship between subjective classification of dental-arch shape, objective analyses via arch-width measurements, and the fitting with the fourth-order polynomial equation.
Ligamentotaxis in the Intraarticular and Juxta Articular Fracture of Wristiosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Role of polycystin 1 in bone remodeling- orthodontic tooth movement study in ...EdwardHAngle
Objective: To test the hypothesis that polycystin-1 (PC1) is involved in orthodontic tooth movement as a mechanical sensor.
Materials and Methods: The response to force application was compared between three mutant and four wild-type 7-week-old mice. The mutant mice were PC1/Wnt1-cre, lacking PC1 in the craniofacial region. An orthodontic closed coil spring was bonded between the incisor and the left first molar, applying 20 g of force for 4 days. Micro–computed tomography, hematoxylin and eosin staining, and tartrate-resistent acid phosphatase (TRAP) staining were used to study the differences in tooth movement among the groups.
Results: In the wild-type mice the bonded molar moved mesially, and the periodontal ligament (PDL) was compressed in the compression side. The compression side showed a hyalinized zone, and osteoclasts were identified there using TRAP staining. In the mutant mice, the molar did not move, the incisor tipped palatally, and there was slight widening of the PDL in the tension area. Osteoclasts were not seen on the bone surface or on the compression side. Osteoclasts were only observed on the other side of the bone—in the bone marrow.
Conclusions: These results suggest a difference in tooth movement and osteoclast activity between PC1 mutant mice and wild-type mice in response to orthodontic force. The impaired tooth movement and the lack of osteoclasts on the bone surface in the mutant working side may be related to lack of signal from the PDL due to PC1 deficiency.
International Journal of Engineering Research and DevelopmentIJERD Editor
Electrical, Electronics and Computer Engineering,
Information Engineering and Technology,
Mechanical, Industrial and Manufacturing Engineering,
Automation and Mechatronics Engineering,
Material and Chemical Engineering,
Civil and Architecture Engineering,
Biotechnology and Bio Engineering,
Environmental Engineering,
Petroleum and Mining Engineering,
Marine and Agriculture engineering,
Aerospace Engineering.
Efficiency of newer generation preadjusted edgewise appliances Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Forces in orthodontics /certified fixed orthodontic courses by Indian dental...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
00919248678078
Functional outcome of Arthroscopic reconstruction of single bundle anterior c...iosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Mandibular arch form the relationship between dental and basal anatomyEdwardHAngle
We investigated mandibular dental arch form at the levels of both the clinically relevant application points of the orthodontic bracket and the underlying anatomic structure of the apical base. The correlation of both forms was evaluated and examined to determine whether the basal arch could be used to derive a standardized clinical arch form.
Transverse growth of the maxilla and mandible in untreated girls with low, av...EdwardHAngle
The purpose of this study was to investigate maxillary and mandibular transverse growth in
untreated female subjects with low, average, and high mandibular plane angles longitudinally from ages 6 to 18.
Purpose: To assess the amount of dental and skeletal expansion and stability after surgically assisted
rapid maxillary expansion (SARPE).
Patients and Methods: Data from 20 patients enrolled in this prospective study were collected before
treatment, at maximum expansion, at the removal of the expander 6 months later, before any second
surgical phase, and at the end of orthodontic treatment, using posteroanterior cephalograms and dental
casts.
Results: With SARPE, the mean maximum expansion at the first molar was 7.48 1.39 mm, and the
mean relapse during postsurgical orthodontics was 2.22 1.39 mm (30%). At maximum, a 3.49 1.37
mm skeletal expansion was obtained, and this expansion was stable, such that the average net expansion
was 67% skeletal.
Conclusion: Clinicians should anticipate a loss of about one third of the transverse dental expansion
obtained with SARPE, although the skeletal expansion is quite stable. The amount of postsurgical relapse
with SARPE appears quite similar to the changes in dental-arch dimensions after nonsurgical rapid palatal
expansion, and also quite similar to dental-arch changes after segmental maxillary osteotomy for
expansion.
Effects of rapid palatal expansion on the sagittal and vertical dimensions of...EdwardHAngle
The purpose of this study was to use cone-beam computed tomography imaging to examine the skeletal and dental changes in the sagittal and vertical dimensions after rapid palatal expansion.
Subjective classification and objective analysis of the mandibular dental arc...EdwardHAngle
Our objective was to evaluate the relationship between subjective classification of dental-arch shape, objective analyses via arch-width measurements, and the fitting with the fourth-order polynomial equation.
Ligamentotaxis in the Intraarticular and Juxta Articular Fracture of Wristiosrjce
IOSR Journal of Dental and Medical Sciences is one of the speciality Journal in Dental Science and Medical Science published by International Organization of Scientific Research (IOSR). The Journal publishes papers of the highest scientific merit and widest possible scope work in all areas related to medical and dental science. The Journal welcome review articles, leading medical and clinical research articles, technical notes, case reports and others.
Role of polycystin 1 in bone remodeling- orthodontic tooth movement study in ...EdwardHAngle
Objective: To test the hypothesis that polycystin-1 (PC1) is involved in orthodontic tooth movement as a mechanical sensor.
Materials and Methods: The response to force application was compared between three mutant and four wild-type 7-week-old mice. The mutant mice were PC1/Wnt1-cre, lacking PC1 in the craniofacial region. An orthodontic closed coil spring was bonded between the incisor and the left first molar, applying 20 g of force for 4 days. Micro–computed tomography, hematoxylin and eosin staining, and tartrate-resistent acid phosphatase (TRAP) staining were used to study the differences in tooth movement among the groups.
Results: In the wild-type mice the bonded molar moved mesially, and the periodontal ligament (PDL) was compressed in the compression side. The compression side showed a hyalinized zone, and osteoclasts were identified there using TRAP staining. In the mutant mice, the molar did not move, the incisor tipped palatally, and there was slight widening of the PDL in the tension area. Osteoclasts were not seen on the bone surface or on the compression side. Osteoclasts were only observed on the other side of the bone—in the bone marrow.
Conclusions: These results suggest a difference in tooth movement and osteoclast activity between PC1 mutant mice and wild-type mice in response to orthodontic force. The impaired tooth movement and the lack of osteoclasts on the bone surface in the mutant working side may be related to lack of signal from the PDL due to PC1 deficiency.
International Journal of Engineering Research and DevelopmentIJERD Editor
Electrical, Electronics and Computer Engineering,
Information Engineering and Technology,
Mechanical, Industrial and Manufacturing Engineering,
Automation and Mechatronics Engineering,
Material and Chemical Engineering,
Civil and Architecture Engineering,
Biotechnology and Bio Engineering,
Environmental Engineering,
Petroleum and Mining Engineering,
Marine and Agriculture engineering,
Aerospace Engineering.
Efficiency of newer generation preadjusted edgewise appliances Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Forces in orthodontics /certified fixed orthodontic courses by Indian dental...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
00919248678078
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Expansion in orthodontics /certified fixed orthodontic courses by Indian dent...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Ortho wires /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Segmented arch technique /certified fixed orthodontic courses by Indian denta...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Anchorage1 (2)/certified fixed orthodontic courses by Indian dental academy /...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Initial alignment and arch leveling with SPEED Appliance, 2nd editionDr Sylvain Chamberland
How to align and level teeht with SPEED brackets? What is the recommended archwire progression? Biomechanics tips and tricks with SPEED. How to avoid problem in the 3rd order plane of space.
Ortho force systems /certified fixed orthodontic courses by Indian dental aca...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Space closure 2 /certified fixed orthodontic courses by Indian dental academy Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Evolution of orthodontic brackets /certified fixed orthodontic courses by In...Indian dental academy
Welcome to Indian Dental Academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
00919248678078
Description :
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Effect of lacebacks in maxillary canine retraction /certified fixed orthodont...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
Effects on the dental arch form using a /certified fixed orthodontic courses ...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
En masse retraction and two step retraction of maxillary /certified fixed ort...Indian dental academy
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and offering a wide range of dental certified courses in different formats.
Indian dental academy provides dental crown & Bridge,rotary endodontics,fixed orthodontics,
Dental implants courses.for details pls visit www.indiandentalacademy.com ,or call
0091-9248678078
A three dimensional finite element analysis of tilted or parallel implant.ppt...enochrao
In the Nobel biocare's model , the so-called All-on-Four protocol, four dental implants are placed in the interforaminal region of the edentulous mandible to support full-arch fixed prostheses.In Nobel biocare’s design, the posterior implants are tilted distally to a maximum of 45 degrees. The soul purpose of this finite element study was to determine and evaluate the stress concentration in peri-implant bone during two different loading conditions and the values obtained , will be used to compare with another design in which the four implants are placed parallel to each other and perpendicular to the occlusal plane. Three-dimensional finite element models consisted of mandibular bone, four dental implants inserted in two different configurations—with the distal implants tilted (model A) or four parallel implants (model S)—and hybrid superstructures. Two loading conditions (178 N/central incisors or 300 N/left first molar) were considered, and von Mises stress values were determined. During anterior loading, higher stress concentrations were detected in the peri-implant bone of all four implants in model A. During posterior loading, lower stress concentrations were observed around the anterior implants of model A; however, the tilted posterior implants were subjected to higher stresses in every condition. Application of either of these designs was successful in reducing peri-implant stress in one loading condition. However, neither design demonstrated better performance in both loading conditions; therefore, within the limitations of this study, neither design demonstrated clearly superior performance.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
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Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Anchorage condition during canine retraction using transpalatal arch with continuous and segmented arch mechanics
1. Anchorage condition during
canine retraction using
transpalatal arch with
continuous and segmented
arch mechanics.
Adel Alhadlaq; Thamer Alkhadra; Tarek
El-
Bialy.
Angle Orthodontist, Vol 86, No 3, 2016
2. INTRODUCTION:
Tooth extraction is an important
step in orthodontic treatment.
The mechanics of closing the
extraction spaces depend on the
diagnostic criteria that dictate the
required type of anchorage.
3. Introduction Continues…
Maximum Anchorage means when less
than one-third of the extraction space is
lost by forward movement of the
posterior teeth.
Moderate anchorage when up to half of
the extraction space is lost by forward
movement of the posterior teeth
Minimum anchorage when more than
two-thirds of the extraction space is lost
by forward movement of the posterior
teeth.
4. Introduction Continues…
The TPA has been widely
used in orthodontics
either with Continuous or
segmented arch
mechanics to minimize
anchorage loss and/or
control rotation of the
upper first molars.
5. Introduction Continues…
It has been recently
suggested that TPA can
control anchorage,
especially when it is
combined with TAD’s.
6. Introduction Continues…
In segmented arch
mechanics, canine retraction
T-loops have been used to
control anchorage during
space closure by modulating
moments of the posterior
teeth part of the T-loop.
7. Introduction Continues…
The aim of this study was to
compare anchorage loss between
two groups of patients who were
treated either with continuous arch
or segmented arch technique
using T-loops to close extraction
spaces while TPA was used to
support the upper first molars.
8. MATERIALS AND METHODS:
Records of 20 orthodontic patients
treated either by continuous arch
technique (n =10) or segmented arch
technique using T-loops and TPA were
studied.
Analyzed records included lateral
cephalometric radiographs before
treatment (T0) and immediately after
complete canine retraction (T1).
This study was approved by the Health
Ethics Review Board at the University of
Alberta, Canada (protocol
9. MATERIALS AND METHODS:
The bracket system used in all
patients was the Synergy bracket
system (0.022 × 0.025 inches;
RMO,Denver, Colo).
The TPA was fabricated from 0.036
stainless steel wire soldered to
previously fit upper first molar bands.
10. MATERIALS AND METHODS:
In the continuous arch wire group,
sliding of upper canines was
performed along 0.018 × 0.025-inch
stainless steel wire using an
elastomeric chain connected between
the upper canines and upper molars’
band hooks (Energy chain, RMO).
11. MATERIALS AND METHODS:
In the segmented arch technique
cases, initial leveling within the buccal
segment was performed using 0.018-
inch round nickel titanium wire (RMO),
and then the posterior teeth (second
premolar to second molar) were
stabilized by rigid 0.018 × 0.025-inch
stainless steel wires (RMO)
12. MATERIALS AND METHODS:
Canine retraction was
performed using a T-loop
fabricated from 0.019 ×
0.025-inch titanium-
molybdenum alloy (RMO).
13. MATERIALS AND METHODS:
The anterior part of the T-loop (alpha)
was bent 35˚ apical, while the
posterior part (beta) was bent 60˚
apical to produce a posterior moment-
to-force ratio of about 12 in the
posterior segment.
14. MATERIALS AND METHODS:
The anterior segment would
produce a moment-to-force ratio of
approximately 6 at 6-mm
activation of the T-loop that is
positioned initially off center
mesially.
15. MATERIALS AND METHODS:
This way, the constructed T-loop
would produce retraction of the
canines with a controlled tipping
movement while the higher moment at
the posterior segment would minimize
the forward movement of the posterior
teeth.
16. MATERIALS AND METHODS:
Also, anterior and posterior toe-in
bends were added to prevent rotation
of the canine during retraction.
The T-loops were reactivated after 3
mm of space closure.
17. Figure 1. (A) T-loop side view. (B) T-loop top view. (C) T-
loop side
intraoral view ; used in segmented arch mechanics.
18. MATERIALS AND METHODS:
Cephalometric radiographs were
obtained at the beginning of the
treatment and after space closure.
All cephalometric radiographs were
digitized using Dolphin imaging
software (Dolphin Imaging &
Management Solution, Chatsworth,
Calif), and Ricketts cephalometric
analysis was used.
19. • Anchorage was assessed by
evaluating the anteroposterior
movement of the distal surface of
the upper first molar to a vertical
line drawn from the Pt point
perpendicular to the Frankfurt
plane
20.
21. RESULTS:
In the continuous arch group, cephalometric
analysis and superimposition showed that
the upper first molars moved forward
significantly (4.5±3, P<.05) compared with
the segmented arch group. (-.7±1.4, P<05)
The molar relationship has become more
class II in the continuous arch group
compared with the segmented arch group
due to the forward movement of the upper
molars ( loss of anchorage).
The Frankfurt-Mandibular plane angle
(FMA) showed a greater increase after
canine retraction in the continuous arch
group than in the segmented arch group, but
the difference was not statistically significant
22. Figure 4. Graph showing anchorage loss in
both segmented and continuous arch
mechanics.
23. Figure 3. Cephalometric tracing
superimposition of a case treated with
continuous arch mechanics.
24. Figure 2. Cephalometric tracing
superimposition of a case treated with
segmented arch mechanics.
25. DISCUSSION:
Although TADs have shown
significant anchorage control in the
literature, their risk of failure and
complications, including loosening or
fracture of the TADs, pain, and soft
tissue inflammation, remain a concern
for some clinicians.
Segmented arch mechanics have not
received wide acceptance in orthodontic
clinical practice, possibly because of
their complexity and challenges facing
the clinician in maintaining a continuous
and reproducible force system.
26. The minimum anchorage loss when
using the segmented arch mechanics
in our study agrees with previous
reports that showed anchorage control
using the beta bend in the retraction T-
loop while using TPA mainly to prevent
the rotation of upper molars.
27. Despite the maximum anchorage
control shown in our study when
retracting the upper canines with the
segmented arch technique, other
reports have shown greater
anchorage conservation when an en
masse vs two-step retraction
approach has been used for maximum
anchorage treatment.
28. The increased FMA after canine
retraction in the continuous arch group
confirms anchorage loss. When the
upper molars move forward, there is
always tendency for them to tip
mesially, which leads to extrusion of
their distal part and consequently
backward rotation of the mandible—
hence, increased FMA.
29. This study is a retrospective study with
a small number of cases.
More prospective controlled clinical
trials may be needed to confirm these
results with a larger sample size and
wide distribution of cases with respect
to their facial forms and anchorage
requirements.
30. CONCLUSION:
The use of a TPA when combined with
segmented arch mechanics results in
more anchorage control than when
used with continuous arch sliding
mechanics during upper canine
retraction.
31. REFERENCES:
1. Burstone CJ. Rationale of the segmented arch. Am J Orthod.
1962;48:805–822.
2. Dalessandri D, Salgarello S, Dalessandri M, et al. Determinants
for success rates of temporary anchorage devices in orthodontics: a
meta-analysis (n . 50). Eur J Orthod. 2014; 36:303–313.
3. Burstone CJ. The segmented arch approach to space closure.
Am J Orthod. 1982;82:361–378.
4. Mezomo M, de Lima ES, de Menezes LM, Weissheimer A
Allgayer S. Maxillary canine retraction with self-ligating and
conventional brackets. Angle Orthod. 2011;81:292–297.
5. Oz AA, Arici N, Arici S. The clinical and laboratory effects of
bracket type during canine distalization with sliding mechanics.
Angle Orthod. 2011;82:326–332.
6. Burrow SJ. Canine rvs conventional edgewise brackets. Angle
Orthod. 2010;80: 438–445.
7. Machibya FM, Bao X, Zhao L, Hu M. Treatment time, outcome,
and anchorage loss comparisons of self-ligating and conventional
brackets. Angle Orthod. 2013;83:280–285.etraction rate with self-
ligating brackets
32. 8. de Almeida MR, Herrero F, Fattal A, Davoody AR, Nanda R,
Uribe F. A comparative anchorage control study between
conventional and self-ligating bracket systems using differential
moments. Angle Orthod. 2013;83:937–942.
9. Moninia AC, Juniorb LG, Martinsc RP, Vianna AP. Canine
retraction and anchorage loss: self-ligating versus conventional
brackets in a randomized split-mouth study. Angle Orthod.
2014;84:846–852.
10. Kuhlberg AJ, Burstone CJ. T-loop position and anchorage
control. Am J Orthod Dentofacial Orthop. 1997;112:12–18.
11. Braun S, Marcotte MR. Rationale of the segmented approach
to orthodontic treatment. Am J Orthod Dentofacial Orthop.
1995;108:1–8.
12. Katona TR, Isikbay SC, Chen J. Effects of first- and
secondorder gable bends on the orthodontic load systems
produced by T-loop archwires. Angle Orthod. 2014;84:350–357.
13. Burstone CJ, Koenig HA. Precision adjustment of the
transpalatal lingual arch: computer arch form predetermination.
Am J Orthod. 1981;79:115–134.
14. Gollner P, Bantleon HP, Ingervall B. Force delivery from a
transpalatal arch for the correction of unilateral first molar cross-
bite. Eur J Orthod. 1993;15:411–420.
33. 15. Ingervall B, Honigl KD, Bantleon H. Moments and
forces delivered by transpalatal arches for symmetrical
first molar rotation. Eur J Orthod. 1996;18:131–139.
16. Ten Hoeve A. Palatal bar and lip bumper in
nonextraction treatment. J Clin Orthod. 1985;19:272–
291.
17. Gunduz E, Zachrisson BU, Honigl KD, Crismani
AG, Bantleon HP. An improved transpalatal bar
design. Part I. Comparison of moments and forces
delivered by two bar designs for symmetrical molar
derotation.
18. Dahlquist A, Gebauer U, Ingervall B. The effect of
a transpalatal arch for the correction of first molar
rotation. Eur J Orthod. 1996;18:257–267.
19. Ingervall B, Gollner P, Gebauer U, Frohlich K. A
clinical investigation of the correction of unilateral first
molar crossbite with a transpalatal arch. Am J Orthod
Dentofacial Orthop. 1995;107:418–425.
34. 20. Kuhlberg AJ, Priebe D. Testing force systems
and biomechanics— measured tooth movements
from differential moment closing loops. Angle
Orthod. 2003;73:270–280.
21. Zablocki HL, McNamara JA Jr, Franchi L,
Baccetti T. Effect of the transpalatal arch during
extraction treatment. Am J Orthod Dentofacial
Orthop. 2008;133:852–860.
22. Bobak V, Christiansen RL, Hollister SJ, Kohn
DH. Stressrelated molar responses to the
transpalatal arch: a finite element analysis. Am J
Orthod Dentofacial Orthop. 1997; m112:512–518.
23. Ingervall B, Go¨ llner P, Gebauer U, Fro¨ hlich
K. A clinical investigation of the correction of
unilateral first molar crossbite with a transpalatal
arch. Am J Orthod Dentofacial
35. 24. Borsos G, Voko´ Z, Gredes T, Kunert-Keil C, Vegh
A. Tooth movement using palatal implant supported
anchorage compared to conventional dental
anchorage. Ann Anat. 2012;194:556–560.
25. Lee J, Miyazawa K, Tabuchi M, Sato T, Kawaguchi
M, Goto S. Effectiveness of en-masse retraction using
midpalatal miniscrews and a modified transpalatal
arch: treatment duration and dentoskeletal changes.
Korean J Orthod. 2014; 44:88–95.
26. Wilmes B, Olthoff G, Drescher D. Comparison of
skeletal and conventional anchorage methods in
conjunction with pre-operative decompensation of a
skeletal class III malocclusion. J Orofac Orthop.
2009;70:297–305.
27. Ricketts RM. New perspectives on orientation and
their benefits to clinical orthodontics—part I. Angle
Orthod. 1975; 45:238–248.
28. Xu TM, Zhang X, Oh HS, Boyd RL, Korn EL,
Baumrind S. Randomized clinical trial comparing
control of maxillary anchorage with 2 retraction