Alzheimer's disease is a neurological disorder that causes memory loss and cognitive decline. It was first described by Dr. Alois Alzheimer in 1901 when examining patient Auguste D. The causes are not fully understood but involve genetic, environmental, and lifestyle factors. Early signs include memory problems and other cognitive declines. As it progresses, damage occurs in areas controlling language, reasoning, and thought, and patients have trouble recognizing family and friends. By the final stage, plaques and tangles have spread throughout the brain, causing severe impairment and dependence on others for care. While some drugs can temporarily stabilize symptoms, there is no cure for Alzheimer's disease.

1. Alzheimer's Disease
The Worst Plague of The 21st Century

2. What is Alzheimer's disease?
Alzheimer's disease is a neurological
disorder in which the death of brain
cells causes memory loss and cognitive
decline.

3. Dr. Alois Alzheimer
The first person to describe this disease

4. The first Alzheimer Patient in History
Auguste Deter

5. The Haunting case of Auguste D.
A 51 years old women, a patient who had
profound memory loss, unfounded suspicions
about her family, shrinkage in her brain and other
worsening psychological changes like, cognitive
and language deficits, auditory hallucinations,
delusions, paranoia and aggressive behaviour.

6. What causes Alzheimer's disease
Scientists don’t yet fully understand what causes
Alzheimer’s disease, but it is clear that it develops because
of a complex series of events that take place in the brain
over a long period of time. It is likely that the causes
include genetic, environmental, and lifestyle factors.
Because people differ in their genetic make-up and lifestyle,
the importance of these factors for preventing or delaying
Alzheimer’s differs from person to person.

7. Signs and Symptoms
Very early sign and symptoms
Memory problems are typically one of the first
warning signs of cognitive loss, possibly due to the
development of Alzheimer’s disease. A decline in
other aspects of cognition, such as word-finding,
vision/spatial issues, and impaired reasoning or
judgment, may also signal the very early stages of
Alzheimer’s disease.

8. Mild Alzheimer's Disease
Alzheimer’s disease progresses,
memory loss worsens, and changes in
other cognitive abilities which are
evident.

9. Moderate Alzheimer’s disease
In this stage, damage occurs in areas of the
brain that control language, reasoning,
sensory processing, and conscious thought.
Memory loss and confusion grow worse,
and people begin to have problems
recognizing family and friends.

10. Severe Alzheimer’s disease
By the final stage, plaques and tangles have
spread throughout the brain, and brain tissue has
shrunk significantly. People with severe
Alzheimer’s cannot communicate and are
completely dependent on others for their care.
Near the end, the person may be in bed most or all
of the time as the body shuts down.

11. Healthy and Affected Neurons

12. Changes occurring in brain on every
stage of Alzheimer’s disease

14. Genetics
Alzheimer's disease have a tendency to
pass from generation to generation. It is
a genetic disease which has maximum
chances of getting inherited from
parents.

15. Diagnosing Alzheimer's disease
To diagnose Alzheimer’s, doctors may:
● Ask questions about overall health, past medical
problems, ability to carry out daily activities, and
changes in behaviour and personality.
● Conduct tests of memory, problem solving, attention,
counting, and language.
● Carry out standard medical tests, such as blood and
urine tests, to identify other possible causes of the
problem.
● Perform brain scans, such as computed tomography
(CT) or magnetic resonance imaging (MRI), to
distinguish Alzheimer’s from other possible causes
for symptoms, like stroke or tumor.

16. Treatment
There is no specific treatment to cure Alzheimer’s
disease completely with the prescribed medicines
as it is most complex disease ever found in history.
There are some prescribed medicines by U.S. food
and drug administration to treat Alzheimer’s
disease but can’t cure it completely, it can just
stabilize the memory and some brain function for
limited period of time.

17. References
http://www.medicalnewstodayhttp://www.medicinenet.com/dementia
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http://www.medicalnewstoday.com/articles/159442.php
http://www.alz.org/alzheimers_disease_what_is_alzheimers.asp
http://www.alzheimers.org.uk/site/scripts/documents_info.php?docu
mentID=100
http://www.nytimes.com/health/guides/disease/alzheimersdisease/overview.html.com/articles/159442.php