This document presents an overview of islet amyloid, IAPP, and their role in type 2 diabetes. It discusses how IAPP is co-secreted with insulin from pancreatic beta cells and forms amyloid fibrils in type 2 diabetes that disrupt cell membranes and cause beta cell death. The document outlines the processing and secretion of IAPP, potential mechanisms of amyloid formation, techniques used to study aggregation, and therapeutic approaches that target inhibition of amyloid formation or removal of existing deposits.