This ppt contains information on the classification, structures, uses and SAR related to macrolide antibiotics, lincomycins and chloramphenicol. It was prepared according to PCI syllabus for B.Pharma graduates
This ppt contains information on the classification, structures, uses and SAR related to macrolide antibiotics, lincomycins and chloramphenicol. It was prepared according to PCI syllabus for B.Pharma graduates
the presentation include the different type of mechanism used by cancer cells to protect them from anticancer agents lead to produce resistance. the slide include definition of cancer as per WHO, type of tumors, treatment of cancer, goal of treatment, problem associated with chemotherapeutic agents, need of studing mechanisms of resistance for anticancer agents, resistance, different mechanism of drug resistance, epigenetics, drug efflux, drug inactivation, DNA damage repair, drug target alteration and cell death inhibitiond
Clinical Pharmacology MCQS
PART CHEMOTHERAPY . Chemotherapy are part of clinical pharmacoloy deal with the infections. this learn about the medicine curing viral infection , bacterial infection , and other parasites such as ascaris , trichomonas etc,.....It ie better that this kind ofmedicne are handled carefully and used properly since the misuse of them cause many socialproblemof death increasing due to the resistance of microbe .
The medical term for tumor (or) cancer is Neoplasm, Which means a relatively autonomous growth (or) un corodinated cell proliferation of body tissue.The branch of medicine which deals with the excessive study of neoplasm (tumor) and its development diagnosis and treatment is called “Oncology.”
The term cancer was translated from a Latin word carcino i.e. Crab by celsus.
For the first time Hippocrates coined the Greek word Karkinos i.e. (crab/cray fish) for malignant breast cancer
Agents used to treat such abnormal cell productions are known as anti neoplastic agents.they are 1.Alkylating agents:-
Nitrogen mustards
Cyclophosphamide
Meclorethamine
2.Antimetabolites:-
purine antagonist:-6-mercaptopurine
Folic acid antagonist:-methotrexate
Pyrimidine antagonist:-5-flurouracil
3.Plant products:-
Vinca alkaloids
Vincrystine
vinblastine
4.Anti biotics:-
Doxorubicin
Actinomycin
5.Hormonal agents:
Tamoxifen
Glucocorticosteroids
6.Miscellaneous:-
Hydroxy urea
Asparginase
Public education campaigns are important in highlighting the dangers of smoking, because possibly as many as 30% of cancers are caused by smoking, excessive drinking, and hazardous solvents, as well as promoting healthy diets and lifestyles.
30% of cancers are diet related that’s why everybody should take healthy diets and lifestyles.
The benefits of eating high-fibre foods, fruit, and vegetables are clear.
Infact, there have been various research projects aimed at identifying the specific chemicals in these foods which are responsible for this protective property.
cancer chemotherapy
Introduction,Types of cancer,Aetiology of cancer,Pathogenesis of cancer,Diagnosis of cancer,Treatment of cancer,Novel drugs for cancer,Future prospects
the presentation include the different type of mechanism used by cancer cells to protect them from anticancer agents lead to produce resistance. the slide include definition of cancer as per WHO, type of tumors, treatment of cancer, goal of treatment, problem associated with chemotherapeutic agents, need of studing mechanisms of resistance for anticancer agents, resistance, different mechanism of drug resistance, epigenetics, drug efflux, drug inactivation, DNA damage repair, drug target alteration and cell death inhibitiond
Clinical Pharmacology MCQS
PART CHEMOTHERAPY . Chemotherapy are part of clinical pharmacoloy deal with the infections. this learn about the medicine curing viral infection , bacterial infection , and other parasites such as ascaris , trichomonas etc,.....It ie better that this kind ofmedicne are handled carefully and used properly since the misuse of them cause many socialproblemof death increasing due to the resistance of microbe .
The medical term for tumor (or) cancer is Neoplasm, Which means a relatively autonomous growth (or) un corodinated cell proliferation of body tissue.The branch of medicine which deals with the excessive study of neoplasm (tumor) and its development diagnosis and treatment is called “Oncology.”
The term cancer was translated from a Latin word carcino i.e. Crab by celsus.
For the first time Hippocrates coined the Greek word Karkinos i.e. (crab/cray fish) for malignant breast cancer
Agents used to treat such abnormal cell productions are known as anti neoplastic agents.they are 1.Alkylating agents:-
Nitrogen mustards
Cyclophosphamide
Meclorethamine
2.Antimetabolites:-
purine antagonist:-6-mercaptopurine
Folic acid antagonist:-methotrexate
Pyrimidine antagonist:-5-flurouracil
3.Plant products:-
Vinca alkaloids
Vincrystine
vinblastine
4.Anti biotics:-
Doxorubicin
Actinomycin
5.Hormonal agents:
Tamoxifen
Glucocorticosteroids
6.Miscellaneous:-
Hydroxy urea
Asparginase
Public education campaigns are important in highlighting the dangers of smoking, because possibly as many as 30% of cancers are caused by smoking, excessive drinking, and hazardous solvents, as well as promoting healthy diets and lifestyles.
30% of cancers are diet related that’s why everybody should take healthy diets and lifestyles.
The benefits of eating high-fibre foods, fruit, and vegetables are clear.
Infact, there have been various research projects aimed at identifying the specific chemicals in these foods which are responsible for this protective property.
cancer chemotherapy
Introduction,Types of cancer,Aetiology of cancer,Pathogenesis of cancer,Diagnosis of cancer,Treatment of cancer,Novel drugs for cancer,Future prospects
Aminoglycosides(medicinal chemistry by p.ravisankar)Dr. Ravi Sankar
Aminoglycosides,Aminocyclitols,Source,Structures of streptomycin,Dihydrostreptomycin,A mention of other aminoglycoside antibiotics,Acid hydrolysis,Mechanism of action,SAR,Dihydrostreptomycin and its importance,therapeutic uses, toxicity.
Kanamycin Injection USP 500mg, 1g Taj Pharma: Uses, Side Effects, Interactions, Pictures, Warnings, Kanamycin Dosage & Rx Info | Kanamycin Uses, Side Effects Kanamycin: Indications, Side Effects, Warnings, Kanamycin -Drug Information –Taj Pharma, Kanamycin dose Taj pharmaceuticals Kanamycin interactions, Taj Pharmaceutical Kanamycin contraindications, Kanamycin price, Kanamycin Taj Pharma Kanamycin SmPC-Taj Pharma Stay connected to all updated on Kanamycin Taj Pharmaceuticals Mumbai. Patient Information Leaflets, SmPC.
This ppt covers the classification of anti psychotics with structures and IUPAC names, MOA, uses, metabolism and side effects. Dopaminergic pathways also given
This ppt covers the classification, structures and IUPAC names, Mechanism of action and uses of individual drugs...under anticonvulsants topic..Side effects/metabolism are also given for few
Beta lactam antibiotics, PCI syllabus for B.Pharm.Purna Nagasree K
This ppt contains beta lactum antibiotics for B.pharm people. the mechanism of action, classification was well explained. Degradations and generations of penicillins and cephalosporins was covered.
It contains classification, SAR, MOA, metabolism and usd of hypnotics and sedatives. Barbiturates and benzodiazepines were discussed as per PCI syllabus. This helps B.Pharm students to learn with focus
This presentation covers about the classification of diuretics, structures with mechanism of action and SAR and therapeutic uses of drugs according to PCI syllabus
This PPT on hypnotics and sedatives covers the Introduction, SAR classification and mechanism of action of drugs listed as per PCI syllabus for in medicinal chemistry for B. Pharmacy
Calcium channel blockers - Medicinal chemistry for B.Pharm.Purna Nagasree K
This ppt describes about the drugs used as calcium channel blockers, their mechanism of action, metabolism and Structure activity relationship of dihydropyridines
Students, digital devices and success - Andreas Schleicher - 27 May 2024..pptxEduSkills OECD
Andreas Schleicher presents at the OECD webinar ‘Digital devices in schools: detrimental distraction or secret to success?’ on 27 May 2024. The presentation was based on findings from PISA 2022 results and the webinar helped launch the PISA in Focus ‘Managing screen time: How to protect and equip students against distraction’ https://www.oecd-ilibrary.org/education/managing-screen-time_7c225af4-en and the OECD Education Policy Perspective ‘Students, digital devices and success’ can be found here - https://oe.cd/il/5yV
The Art Pastor's Guide to Sabbath | Steve ThomasonSteve Thomason
What is the purpose of the Sabbath Law in the Torah. It is interesting to compare how the context of the law shifts from Exodus to Deuteronomy. Who gets to rest, and why?
This is a presentation by Dada Robert in a Your Skill Boost masterclass organised by the Excellence Foundation for South Sudan (EFSS) on Saturday, the 25th and Sunday, the 26th of May 2024.
He discussed the concept of quality improvement, emphasizing its applicability to various aspects of life, including personal, project, and program improvements. He defined quality as doing the right thing at the right time in the right way to achieve the best possible results and discussed the concept of the "gap" between what we know and what we do, and how this gap represents the areas we need to improve. He explained the scientific approach to quality improvement, which involves systematic performance analysis, testing and learning, and implementing change ideas. He also highlighted the importance of client focus and a team approach to quality improvement.
How to Split Bills in the Odoo 17 POS ModuleCeline George
Bills have a main role in point of sale procedure. It will help to track sales, handling payments and giving receipts to customers. Bill splitting also has an important role in POS. For example, If some friends come together for dinner and if they want to divide the bill then it is possible by POS bill splitting. This slide will show how to split bills in odoo 17 POS.
Palestine last event orientationfvgnh .pptxRaedMohamed3
An EFL lesson about the current events in Palestine. It is intended to be for intermediate students who wish to increase their listening skills through a short lesson in power point.
The Roman Empire A Historical Colossus.pdfkaushalkr1407
The Roman Empire, a vast and enduring power, stands as one of history's most remarkable civilizations, leaving an indelible imprint on the world. It emerged from the Roman Republic, transitioning into an imperial powerhouse under the leadership of Augustus Caesar in 27 BCE. This transformation marked the beginning of an era defined by unprecedented territorial expansion, architectural marvels, and profound cultural influence.
The empire's roots lie in the city of Rome, founded, according to legend, by Romulus in 753 BCE. Over centuries, Rome evolved from a small settlement to a formidable republic, characterized by a complex political system with elected officials and checks on power. However, internal strife, class conflicts, and military ambitions paved the way for the end of the Republic. Julius Caesar’s dictatorship and subsequent assassination in 44 BCE created a power vacuum, leading to a civil war. Octavian, later Augustus, emerged victorious, heralding the Roman Empire’s birth.
Under Augustus, the empire experienced the Pax Romana, a 200-year period of relative peace and stability. Augustus reformed the military, established efficient administrative systems, and initiated grand construction projects. The empire's borders expanded, encompassing territories from Britain to Egypt and from Spain to the Euphrates. Roman legions, renowned for their discipline and engineering prowess, secured and maintained these vast territories, building roads, fortifications, and cities that facilitated control and integration.
The Roman Empire’s society was hierarchical, with a rigid class system. At the top were the patricians, wealthy elites who held significant political power. Below them were the plebeians, free citizens with limited political influence, and the vast numbers of slaves who formed the backbone of the economy. The family unit was central, governed by the paterfamilias, the male head who held absolute authority.
Culturally, the Romans were eclectic, absorbing and adapting elements from the civilizations they encountered, particularly the Greeks. Roman art, literature, and philosophy reflected this synthesis, creating a rich cultural tapestry. Latin, the Roman language, became the lingua franca of the Western world, influencing numerous modern languages.
Roman architecture and engineering achievements were monumental. They perfected the arch, vault, and dome, constructing enduring structures like the Colosseum, Pantheon, and aqueducts. These engineering marvels not only showcased Roman ingenuity but also served practical purposes, from public entertainment to water supply.
Unit 8 - Information and Communication Technology (Paper I).pdfThiyagu K
This slides describes the basic concepts of ICT, basics of Email, Emerging Technology and Digital Initiatives in Education. This presentations aligns with the UGC Paper I syllabus.
Ethnobotany and Ethnopharmacology:
Ethnobotany in herbal drug evaluation,
Impact of Ethnobotany in traditional medicine,
New development in herbals,
Bio-prospecting tools for drug discovery,
Role of Ethnopharmacology in drug evaluation,
Reverse Pharmacology.
2024.06.01 Introducing a competency framework for languag learning materials ...Sandy Millin
http://sandymillin.wordpress.com/iateflwebinar2024
Published classroom materials form the basis of syllabuses, drive teacher professional development, and have a potentially huge influence on learners, teachers and education systems. All teachers also create their own materials, whether a few sentences on a blackboard, a highly-structured fully-realised online course, or anything in between. Despite this, the knowledge and skills needed to create effective language learning materials are rarely part of teacher training, and are mostly learnt by trial and error.
Knowledge and skills frameworks, generally called competency frameworks, for ELT teachers, trainers and managers have existed for a few years now. However, until I created one for my MA dissertation, there wasn’t one drawing together what we need to know and do to be able to effectively produce language learning materials.
This webinar will introduce you to my framework, highlighting the key competencies I identified from my research. It will also show how anybody involved in language teaching (any language, not just English!), teacher training, managing schools or developing language learning materials can benefit from using the framework.
1. MEDICINAL CHEMISTRY III
B. Pharmacy III/IV (Scond sem.)
Dr. K. Purna Nagasree
M.Pharm. (BITS, Pilani), Ph.D., PDF (DST, WOSA)
Associate Professor
VIGNAN INSTITUTE OF PHARMACEUTICAL
TECHNOLOGY
(Approved by PCI, AICTE New Delhi and affiliated to JNTUK)
ANISO 9001:2015, ISO 14001:2015, OHSAS 18001:2007 Certified institution, beside VSEZ, Duvvada,
Vishakapatnam-530049, Andhra Pradesh, India
2021
3. The aminoglycosides each contains one or more amino
sugars, such as glucosamine or neosamine, linked by
glycosidic linkages to a basic (amino or guanidine) six-
membered carbon ring.
These are broadspectrum antibiotics, and in general they
have greater activity against gram-negative than gram-
positive bacteria.
Aminoglycosides
4. The toxicity of these agents is dose-related, and therefore every
individual can get these side effects provided the dose is
sufficiently high enough.
Because of their potential for ototoxicity and nephrotoxicity,
aminoglycosides are administered in doses based on body
weight.
Vestibular damage, hearing loss, and tinnitus are irreversible, so
care must be taken not to achieve a sufficiently high dose.
Toxicity
5. Concomitant administration of a cephalosporin may lead to
increased risk of nephrotoxicity, while administration with a
loop diuretic increases the risk of ototoxicity.
These properties have limited the use
Some can be administered for ophthalmic and topical
purposes
Toxicity
6. Aminoglycosides work by binding to the bacterial 30S
ribosomal subunit, so causing misreading of mRNA,
leaving the bacterium unable to synthesise proteins
vital to its growth
Mechanism of action
8. Waksman (1944) and his associates, who isolated it from a strain
of Streptomyces griseus
The organism, S. griseus, releases the other substances, such as
hydroxystreptomycin, mannisidostreptomycin, and
cycloheximide, but do not reach up to the required
activity/potenc y level.
resistant strains of bacteria and chrnic toxicity major drawbacks
It is an aminoglycoside antibacterialo also used as an
antitubercular drug
Streptomycin
9.
10. Neomycin is a mixture of closely related epimers, neomycin B,
and C. Neomycin B differ from neomycin C by the nature of the
sugar attached terminally to D-ribose, this sugar called
neosamine.
It is photosensitive and its main use is in the treatment of the
ear, eye, and skin infections; these include burns, wounds,
ulcer, and infected dermatoses.
Neomycin
11.
12. The mixture consists of three related structures, that is,
Kanamycin A, B, and C.
The kanamycins do not possess D-ribose molecule that is present
in neomycins and paramomycins.
kanamycins used treat to infections of the intestinal tract and to
systemic infections.
Kanamycin
