World Fastest NIR System; Non-destructive Hardness & Disintegration Analyzer; One of Largest Spectral Local Database; Speed: 180 Analyses/Second/ Probe Precision(Concentration): 0.01% Precision(Weight): 25 ppm Sensitivity: 0.1%

1. Ivy Lee
@IvyLeeSensorX
Marketing Director
@AmericanSensorX
August, 2016
One of Advanced Sensor Tech : SpectRx™ FFT-NIR
Lightning Speed & Hardness Test Game Changer
1

2. 222222
Advanced Sensor Tech
Partnering In Fashion SensorX
• Water Food Health
Climate Safety
Modernization
Cloud
• Quality Life System
Industry & Stock IoT
• Smart Dust, NASA
Style City IoT
• Quantum Color/
Hardness/ Chem/
Bio
• Positioning & ID
Chip (Standard
• Pose, V2V,
• Industry Robot)
•
• SiteSocial
M2C
(Operator Open Platform)
C2M
M&A
Corp Rating
Stock IoT
Me-Too
Nano Sensor
Natural
Infrastructure
Longevity
System OS
Nano-MEMS
MEMS Sensor
Neural Network
Robot
3D Printer
FFT
2
SensorX

3. 33
InspectRx® : um Particle
SpectRx™: Chemical Composition, 0.01% Concentration, 1 PPM Weight, 0.1% Sensitivity
Nano Positioning & ID-Chip Sensor: Deploy Micro Dot to Secure Asset, Life, Serve Business
SensorX
Advanced Nano Sensor Program in High Dynamic Device IoT
@SensorXClimate, Your 12.5 Milliseconds AQI
Wearable InspectRx® -SpectRx™-Nano Positioning & ID Chip Sensor--Environment

4. 44
Human Blood Composition and Gene Changed
by Air/ Water/ Goods with Toxic Chemical/ Heavy Mental
( You Don’t Know, Haven’t Adopted Our Right Tech Machine & Device to Find Everywhere Yet )
SensorX
Chemicals in Plastic Home Products Linked to Health Issues JULY 9, 2015, 8:13 AM
http://www.cbsnews.com/videos/chemicals-in-plastic-home-products-linked-to-health-issues

5. 55555
Fat Thickness ≤ 150mm or Requested
Structured Diffused Light Energy
(SpectRx™ Emission Spectroscopy
Fluoresce)
InspectRx® Upper Camera
Lower Camera
SensorX
Inspect-Analyze Animal Parasite, Infected Cysts, Metallic Foreign Objects & Drug Residue
Advanced Nano Sensor Program in Health IoT
SpectRx™ Fluoresce Direct & Indirect Sensing Molecular ( Virus, Tumor, Fluid, Odor, PH) - InspectRx®
Remote Sensing (Skin Color Number) - MedBed - 3D PrinterX Precision Medicine.
Track Life Intervention, Quantify Quality Yield, Analyze & Evaluate Diagnostic System, Communicate
Data, Positively Impact on Human MTBF>150 Years

6. 66
SpectRx™ FFT-NIR + InspectRx® Special Light
Analyze
• Fat/Protein/Moisture Contents
• Infected Cysts, Parasites & Drug Residue
InspectRx®
• UX Phys: Color Number
• UX Bio: Bacteria, Virus
• 3D Size
Calculate
• Area
• Thickness
• Volume
• Fat/ Protein Percentage
• Weight
• Accumulation
• Price Per Weight
SensorX
Inspect-Analyze Animal Skin/ Protein Color, Fat/ Protein Percentage, Fat/ Protein/ Moisture Contents
Advanced Nano Sensor Program in Health IoT
SpectRx™ Fluoresce Direct & Indirect Sensing Molecular (Virus, Tumor, Fluid, Odor, PH) -
InspectRx® Remote Sensing (Skin Color Number) - MedBed - 3D PrinterX Precision Medicine.
Track Life Intervention, Quantify Quality Yield, Analyze & Evaluate Diagnostic System, Communicate
Data, Positively Impact on Human MTBF>150 Years

7. 7
SpectRx™ FFT-NIR Tech
Frost & Sullivan Spectroscopy Inspection Tech Excellence
2006-

8. 8
 World Fastest Speed:
Type1: 180 Analyses/Second/Probe
Type2: 80 Analyses/Second/Probe
 Precision(Concentration): 0.01%
 Precision(Weight):
Type1: 25 PPM
Type2: 1 PPM
 Sensitivity: 0.1%
 Penetrate 5mm Depth
 Spectra: Millions
 Wave Length: 830-2500nm
 Real Time Production
 Close-Loop System
 Total Integration with Production
Machine
 Incoming Inspection and
Verifications
 In-process Inspection
 Maintains Consistent Quality
8
IR-Based Vision System
8
Solid – Powder – Liquids – Semi-Solid – Gas
SensorX

9. 9
Probe
Object
Fiber Optic CablesDetector
Spectrometer
Multi-online Process Apps—Pharma, Food, Polymer
Product Streams under 2, 80 Probes
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80 SpectRx™ Probes
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10. 10
Redesigned for JNJ Stent
10Analysis of Stents of Same Polymers
with Different Active Concentrations
Stents of Different Polymers
with Same Constant of Active Layer
Each Stent Includes
Micro-composition of Drug Contents
Deposited between Polymer Layers SpectRx ™-Stent Online Process
SensorX

11. 1111
Redesigned for FilleRx® Inspection & Packaging System
-- NIR Light Source ( Compact Probe )
SensorX
Type1 Speed
5 Milliseconds/ Analyse/ Probe
Light Source Intensity
 Stronger beam divided by 10 mm Prism
 Cover glass in sensor (detect UV
radiation) is made of UV permeable
quartz glass
Competitive: NIR Light Source Signal Transmission
Reflected Signal Detection Data Analysis Process

12. 12121212
Lab App - Pharm, Food, Agri, Oil & Gas, Chemical
Samples on Turntable
Three Plug and Play Modules
1. Near Infrared Fiber Optic, Probe
2. InSb Detector
• Analogue-to-digital Converter
• Electromagnetic Interferometer
(100 + times data)
• Digital Signal Processor
3. An Automated Indexer
A PLC
Sensors
Competitive: NIR Light Source Signal Transmission
Reflected Signal Detection Data Analysis Process
SensorX

13. 1313
 Quantum Hardness UX:
electronegativity & hardness predict
chemical behavior (ionization energy,
electrophilic & toxicity), correlate with
visible-UV spectra.
 Hardness: governed dissolution from
tablet to smallest particles after broken
by ―disintegration‖ (energy) over all
stages (time)
Sabrie Index (FDA Approved)
 Widely used among scientists &
physicists.
 Non-destructive identification
hardness & disintegration by the
InspectRx® & SpectRx™ correlation
with the energy absorbed or reflected
 InspectRx® vision inspects in physical
properties.(U.S. Patent 5,679,954)
 SpectRx™ FFT-NIR analyzes organic
and inorganic in compound
properties.(U.S. Patent 5,900,634)
13• The only automated system can detect hardness & disintegration without destroying
• Achieved by applying neural network analysis using Sabrie’s Index.
Tech Advantage 1. IR-Based Vision System
Analyze Compound Property – Hardness by Sabrie Index
(Sabrie Soloman Law of Solid Dosage Disintegration & Light Absorbed Energy)
SensorX

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Solid - Tablets-Capsules-Polymer
 Diffused Reflectance
 Tablet Hardness & Friability
 Tablet Disintegration
 Chemical Composition
Active Ingredients
Impurities
Moisture Content
Homogeneity
 Tablet Cracks
 Capsule Deterioration
14
Tech Advantage 1. IR-Based Vision System
Analyze Physical & Chemical Properties by Solid/ Liquid/ Gas Probe
Liquid - Gels – Ointments - Gas
• Transmission
• Chemical Composition
Active Ingredients
Impurities
Concentration
Homogeneity
• Air-Bubbles
• Oxygen
• Acidity
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15. 1515
Tech Advantage 2. Speed
Time Dispersion and Time / Spatial Separation beyond Classical FFT(Fast
Fourier Transform) Spectrometer
Classical advantages of FFT spectrometry
over dispersive spectrometry:
• Multiplexing  all wavelengths fall on
the detector at all times
• Throughput  the aperture vs resolution
limitation is reduced
• Wavelength accuracy  the internal
laser ensures stability in ppm levels
SpectRx™ further superior:
It relies on time not spatial dispersion of the
spectral information. This limits the number
of moving components and provides a more
reliable observation geometry. In practice, it
is
• Higher spectral resolution.
• Larger bandwidth, more spectral channels
• Flexibility: because of the complete
separation of spectral information
(performed in the time domain) and spatial
information (performed in the spatial
domain),The spectral resolution can be
instantly changed by computer. The field of
view configuration can be changed in the
field, simply by changing telescope
modules.
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SensorX
Competitive: NIR Light Source Signal Transmission
Reflected Signal Detection Data Analysis Process

16. 1616
Tech Advantage 3. Radiometric Accuracy
Influenced by
1. Calibration Source Errors
Relative radiometric errors at 5000
cm-1, 2860 cm-1, and 2000 cm-1
(2 m, 3.5 m, and 5 m) due to the
uncertainty of the calibration source
temperature, assuming a blackbody
relative temperature accuracy of 0.2%
and an absolute accuracy of 1°.
The maximum error is 5% for the
coldest source (TS=373K) at the
highest frequency(=2860cm-1). This
is a very pessimistic value.
.
2. Calibration Drift
InSb detectors exhibit much less
variation of responsively with
respect to temperature.
We typically use 2% as the relative
radiometric accuracy due to drift,
and assume that the corresponding
time interval between
characterisation and scene
measurement is long enough to
allow measurement.
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17. 1717
3.Spectrometer Intrinsic linearity
Detector Non-Linearity Error
The saturation level is never reached
because the feedback resistors used
are high enough so that preamplifier
saturation occurs before there is
detector saturation. We therefore do
not anticipate detector non-linearity
problems in InSb detectors.
Channel Spectrum Error
A certain degree of wedging a
parallel-face protective window would
further reduce the channel spectrum
but at the cost of introducing the
phenomenon of ghost images.
Spectral Aliasing Error
An optical filter provides both a sharp
cut-off and very high attenuation
outside the spectral range of interest.
This method also reduces photon
noise.
Tech Advantage 3. Radiometric Accuracy
Influenced by
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18. 181818
Tech Advantage 4. Sensitivity: 0.1%
Signal / Peak Noise Amplitude = 3 (SNR 300%, as Signal Quality 25-30% is
Usable in Practice)
18
Really Simple
Syndication
Scene Radiation
Detector Irradiance
Detector Current
Photon Noise Johnson Noise
Jitter Noise
ADC Noise
Dark Noise
Noise Equivalent Spectral Radiance
Signal to Noise Ratio
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19. 191919
Input – Use Spectra
as Input Layer - Data
Output
Input
Hidden Layers
Input Layers
Output Layers
Output – Such As Active Ingredients
by Weight
Tech Advantage 5.
SensorX Sophisticated Neural Network Analysis
SensorX

20. 20
Windows-based data
manipulation and processing
module
• View, process, and organise
data. It allows easy data and
graphics exchange with other
Windows applications such
as spreadsheet and word
processors.
• Data processing capabilities
are fast and accurate. It
includes a built-in
programming language,
Array Basic, so that
advanced users can modify
existing algorithms or create
new ones for the individual
requirements of specific
experiments.
―C++/Visual Basic‖ Windows® based acquisition
module—Research Acquire
1. Necessary functions:
• Raw interferograms
• Un calibrated spectra
• Radiometric reference spectra using calibrated
sources
• Calibrated spectra
• FFTNIR or FFTIR-type data in transmission, such as
raw, reference, transmittance and absorbance spectra,
which can be useful for quick diagnostics in such
things as the measuring of stability, the transmission
capacity of optical filters, and a general examination of
the spectral content of the source observed.
2. A basic display system and a set of post-processing
functions
• Perform radiometric calibration
• Conversion to temperature units
• Integration over programmable bands
• Computation of theoretical Planck functions, addition,
subtraction, multiplication, and ratios.
20
Tech Advantage 6.
Software Philosophy
SensorX

21. 21
Tech Advantage 7. Data Flow Outlines
Data: Notions of Size, Type, Transfer Rate
SpectRx™ Functions: Scan Speed, Spectral Resolution, Spectral Range
Temporal & Spectral Data Types: 1. Involved in FT Spectroradiometer ; 2. Are Linked by Fourier Transform
• The scan length is a function of resolution.
• All wavelengths are acquired
simultaneously whatever the scan length
is.
• SpectRx™ systems acquire double-sided
interferograms.
• The sampling rate is a function of the
scanning speed and of the number of
samples per fringe or oversampling factor.
• The maximum observable spectral range
is determined by the oversampling factor.
In the SpectRx™ the oversampling factor
can be 1 (no oversampling) or 2, this
provides for spectral ranges of 0 to 7899
cm-1 and 15798cm-1 respectively.
• Each data point is stored as a 16-bit
number. Coherent addition or signal
averaging is done with 32 bit numbers.
• The maximum number of interferograms,
which can be recorded in kinetic mode,
depends on the size of the DRAM buffer.
This is 4 MB (expandable to 64 MB) in the
case of the SpectRx™ 100, and 64 MB in
the SpectRx™ 200.
• The required scanning speed is dictated
by how fast an event is to be resolved; it
is limited by the ADC speed, the detector
response time, and the throughput of the
electronics, including the communication
links. It is 1 cm/s in the SpectRx™ 100
and 25 cm/s in the SpectRx™ 200.
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Tech Advantage 8.
One of World Largest Spectral Database (Millions)
Comparing to stored ―gold standard
sample‖
It can enter the verification and
validation to maintain quality and
consistency.
In case of unknown composition
A 95% chance of unknown
composition can be found through
millions of spectral diagram ( local
database), unless the composition of
signal to noise ratio is too small.
SensorX

23. Tech Advantage 9.
SpectRx ™ FFT – NIR Spectroscopic Methods
23
Emission Spectroscopy
Fluorescence
Light Source
Measurement
Reflection Absorbancy
Infrared
Spectroscopy
UV
spectroscopy
Laser
Spectroscopy
Transmission
Every sample has its own specific spectral ―fingerprint.‖
Unlike other analytical procedures, the samples do not need time-consuming preparation.
SensorX

24. Emission Spectroscopy Fluorescence
In Biology, Materials, Production Oversight
(Refer to Biosensor Dev.)
Measure an excitation spectrum,
• The fluorescent sample is
illuminated with different
wavelengths one after another.
• The intensity of the fluorescent
radiation is measured at a fixed
wavelength.
• The intensity measured at this
wavelength is applied at the
excitation wavelength.
Measure an emission spectrum,
• with a fixed wavelength.
• The sample emits fluorescent
radiation over a wide range of
wavelengths.
• The intensity emitted is applied at
the particular emission wavelength.
24Light source measurement is commonly used in emission spectroscopy area.
UV Spectroscopy is primarily executed as absorption and fluorescence spectroscopy.
SensorX

25. Light Source Measurement
In Physiological Criteria Evaluation
Calibration source errors, the first type of three
errors influence radiometric accuracy(P8), are
deviations in the production of a perfect
calibration source.
These errors include the accuracy of blackbody
temperature and the accuracy of its emissivity
over the operational spectral range.
25Light source measurement is commonly used in emission spectroscopy area.
SensorX

26. 26
Laser Spectroscopy
As Light Source
The laser is used
• A light source for excitation
• Illuminating the sample for
absorption measurement.
• If the sample is excited by the laser,
the sample itself begins to emit
radiation. The spectrometer records
the radiation at a right angle to the
direction of the radiation excitations.
• If the sample absorbs the laser beam,
the sample is placed between the
laser and the spectrometer.
26Light source measurement is commonly used in emission spectroscopy area.
SensorX

27. Absorbance
For Materials In Water and Gas
Measure monochromatic radiation
For materials in water solution or gas,
optical density is directly proportional
to the concentration of the material.
Measure cloudy samples
• A sensible choice of reference
measurements must be made.
• Both absorption and reflection
measurement values change as a
result of the dispersion of the radiation.
In order to get real spectra, the
reference measurements in the
observed wavelength range must be
transparent but display a comparable
dispersion.
27UV Spectroscopy is primarily executed as absorption and fluorescence spectroscopy.
SensorX

28. Reflection
The sample reflects the radiation
diffusely; the directly reflected radiation
is coupled out through the gloss
trap. Only the diffuse reflection is
coupled into the optical fiber.
The reference measurement is measured
against a comparable strongly diffuse
reflecting white reference standard
(Spectralon).
The spectrometer is reset to reflection
measurement. The reflectance from the
wavelength can be read off on the
spectrometer
28
SensorX

29. Transmission
1.The spectrometer is set to absorption.
• First, the radiation intensity and
special diffusion of the light source
are measured. This reading is the
reference measurement.
• The sample is then fixed into the
holder.
2.Set to transmission
• A spectrum is then taken.
•
• Depending on the setting, the
transmission can be displayed as a
percentage or transmittance from the
wavelength.
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SensorX

30. Infrared Spectroscopy in Organic Materials
UV Spectroscopy in Drinking Water, Chlorophyll &
Photosynthesis
They are separate fields, places special
demands on the spectrometer.
IR spectroscopy has become extremely
important because the molecular
vibrations have an effect on the
spectrum in infrared. Nearly all organic
materials exhibit specific absorptions
in the near infrared.
30
UV Spectroscopy is primarily executed as absorption and fluorescence spectroscopy.
SensorX

31. 31
SpectRx™ Software Programming Guide
Run Manual Mode
1. Set sample standard
• In case of known conditions as P12-
P13, for instance,
① Hardness, disintegration, sabrie index
② Weight : chemical compositions, active
ingredients
③ Content : air humidity, sample moisture
• In case of unknown composition, 95%
can be found in local database.
2. Set upper & lower control limits on
production screen
3.Set spectroscopic methods.
Run Auto Mode
1. Accept – Reject - Quarantined
An acceptable product must fall
between upper & lower control limits
2. Data Storage, implementation,
validation
Training and Development
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32. 3232323232Auto Mode / Manual Mode
Chemical Composition Spectrum Deviation
Set as (Golden) Standard
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33. 333333Active Ingredients Weight & Spectrum Deviation
Air Humidity, Product Moisture Content
Set as (Golden) Standard
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34. 34
Sabrie Index, Hardness, Disintegration & Spectrum Deviation 34
Set as (Golden) Standard
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35. 353535Production Screen Describing UCL & LCL
An Acceptable Product Must Fall
Between Upper & Lower Control Limits
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36. 3636
Data Storage & Implement & Validation
Experience Lab-Precision, Online Production-Speed in Large Corps
• UI
 (Production) Monitor Interface(MI)
 Operator/Supervisor/Admin
Interface(OI)
 Global Program Parameters
Interface (PI)
• FDA Compliance Package
( Data Storage & Implement)
• Data Security (Massive,
Permanent E-Document / Image
Classification & Records)
• Global Sites Network
• Servers
36Currently, 50% of global production data are inactive.
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37. 3737
American SensoRx, Inc. USA
The SpectRx™ FFT-NIR Technology
Advanced Sensor Technology
Ms. Ivy Lee
Online Marketing & Finance Director
31 North Monroe Street
Ridgewood, New Jersey, 07450 USA
in: IvyLee@AmericanSensorX.com
WeChat / t: @IvyLeeSensorX
Tel: 001 201 447 8999 Fax: 001 201 447 8998
Linkedln Company Page
https://plus.google.com/+IvyLee/about ( Links- Contributor to )
www.facebook.com/SmartSensorX
http://www.slideshare.net ( Search “SensorX” , 2 pages )
www.AmericanSensorX.com