Indatech Beyond Spectroscopy is an innovative company, with expertise in optical measurements for on-line monitoring and controlling industrial processes. Raman NIR UV Spectroscopy; Hyperspectral imaging; Spatialy Resolved Spectroscopy

1. Make your process :
 Faster to develop
 Efficient
 Safer

2.  INDATECH designs, builds, sells and
supports optical solutions for process
development and monitoring
 Products: Spatially Resolved
Spectroscopy (SRS) solutions, Raman
spectroscopy systems
 Market: research laboratories,
pharmaceutical, biotechnological,
chemical industries
 Differentiators:
• Exclusive patented technology (SRS)
• Solutions for non-destructive, real-
time control on-line or in laboratories
• Systems adapted to all product types
(solid, liquid, complex)
• Simultaneous measurement of both
chemical and physical properties (SRS)
Activity
Management & Shareholders
 Date of creation: 2009
 Management: Dr Sylvie Roussel (PhD),
CEO
Dr Fabien Chauchard (PhD), General
Director
 Shareholders:
Management
Venture funds (Sofimac, Soridec)
Pellenc Selective Technologies
 Location: Clapiers (34)
 ISO9001
2
A French Spectroscopy Innovator
We provide Non-invasive and non-destructive Industrial Analyzer based on
innovative optical technologies

3. High-Tech References and Prospects
3
 Accomplishments:
 Experience of meeting the needs of large multinationals
 High Tech solutions adaptable to different customers
 Various fields of application (types of products and processes controlled)
 Successful use by clients for at least 2 years (selected references listed below)
 A technology valided by technical application research center:
2010
GlaxoSmithKline (UK)
Indatech’s Hy-Ternity®
Detection of API
agglomerate and powder
homogeneity
2012
Imeca Process (FR)
Indatech’s SPOT4Line®
Cleaning In Place
Control
2013
Servier Laboratoires (FR)
Indatech’s ®/Hy-Ternity ®
Real time measurements of
pharmaceutical drug dosage
and uniformity
2014
Procter & Gamble (B)
Indatech’s Viserion ®
Liquid products analysis
& control (RAMAN)
SPOT4LINE

4. Different processes
4
API concentration
Weight
Moisture content
Particle size
Polymorphism
Density
Porosity
Crystal attrition
Moisture
content
Homogeneity
Homogeneity
Mean particle
size
Integrity
Weight
Hardness
Thickness
friability
Moisture
Coating
thickness
Wet or Dry
granulation
Drying and
freeze-drying
Blending,
extrusion,
milling and
Mixing Compression
Coating
Process optimisation
and End point detection
Crystallisation
Mean particle size
Polymorphism
Solvent
composition
Toward Real Time Release
Lyophylisate
Upstream
Downstream
Purity
CPP (Glucoe
etc..)
Moisture,
homogeneity

5. What are the
Different level of need
5
Better understanding of processes
More robust scale-up
Decrease of qualification costs
Reduction of non-conformities
Reduced Time to market

6. 6
Hyternity®
APPLICATIONS :
FREEZE DRIED
PRODUCT
CAPSULE FILLING
MIXING
 Accurate analysis of weight and API
 Other critical parameter analysis:
dosage, uniformity, hardness, moisture
 Works also with tablets
98 % Filled capsule Capsule capacity API-NESS accuracy
standard 100-550mg 30mg
micro 3-80mg 0.3mg
Example of weight accurcay
Specifications
 VIS/NIR sensor : several option available 400-1000nm (ccd), 950-1700nm
(InGaAs), 1000-2000nm (InGaAs).
 27 simultaneous measuring points:
 Fast: Typical acquisition speed for 27 measurement 3ms, lower on demand.
 Unique SRS capabilities : can work with one or several SRS probes
 IP54 (65 on demand)
 CF21Part 11 Software :, SRS Ready software + CAMO process pulse II,
machine communication capabilities
probes

7. 7
Hyternity®
Specifications
 VIS/NIR sensor : several option available 400-1000nm (ccd), 950-1700nm
(InGaAs), 1000-2000nm (InGaAs).
 27 simultaneous measuring points:
 Fast: Typical acquisition speed for 27 measurement 3ms, lower on demand.
 Unique SRS capabilities : can work with one or several SRS probes
 IP54 (65 on demand)
 CF21Part 11 Software :, SRS Ready software + CAMO process pulse II,
machine communication capabilities
APPLICATIONS :
FREEZE DRIED
PRODUCT
CAPSULE FILLING
MIXING
 Accurate analysis of residual moisture : threshold detection of
residual moisture 0.2%, Range 0.2 to 5% water content
 Critical parameter analysis : dosage, uniformity, contamination (glass
plastic, melt)
 Fast Analysis without consumable

8. 8
Hyternity®
APPLICATIONS :
FREEZE DRIED
PRODUCT
CAPSULE FILLING
MIXING
 Accurate analysis of : Mean particle(or globule) size down to 200nm,
Chemical concentration, turbidity.
 Understanding of critical phenomenon: sedimentation, attrition,
local fouling, dead zone identification, unstability
 Different product : powder solid/solid, solid into liquid, emulsion
liquid/liquid
 Multipoint and quick analysis (can be used to improve simulation)
Specifications
 VIS/NIR sensor : several option available 400-1000nm (ccd), 950-1700nm
(InGaAs), 1000-2000nm (InGaAs).
 27 simultaneous measuring points:
 Fast: Typical acquisition speed for 27 measurement 3ms, lower on demand.
 Unique SRS capabilities : can work with one or several SRS probes
 IP54 (65 on demand)
 CF21Part 11 Software :, SRS Ready software + CAMO process pulse II,
machine communication capabilities

9. Viserion®785
9
Specifications
 Excitation laser : 785nm, 500mW , stabilized laser diode robust and
long life
 High sensitivity detector: 2048 x70 pixels, low noise, deep cooled
sensor. 300-3200cm-1 (200-3000cm-1 also available)
 Flexibility : Different probes and immersion tube available. Dedicate
probe for biotechnology
 IP54 (65 on demand)
 Software : CF21Part 11, Viserion® Ready software + CAMO process
pulse II, machine communication capabilities
APPLICATIONS :
Cell culture
monitoing
Chemical liquid
analysis
 Up Stream and Down stream solution
 Critical process parameter :Glucose, polysaccharide, Lactate, vitamin,
protein…
 Accurate prediction : typical 0.2g.l
 Specific design for biotech : PG13.5 connector, different tube length,
autoclavable

10. Viserion®785
10
Specifications
 Excitation laser : 785nm, 500mW , stabilized laser diode robust and
long life
 High sensitivity detector: 2048 x70 pixels, low noise, deep cooled
sensor. 300-3200cm-1 (200-3000cm-1 also available)
 Flexibility : Different probes and immersion tube available. Dedicate
probe for biotechnology
 IP54 (65 on demand)
 Software : CF21Part 11, Viserion® Ready software + CAMO process
pulse II, machine communication capabilities
APPLICATIONS :
Cell culture
monitoing
Chemical liquid
analysis
 Identification : Direct identification of laundry product (more than 20
different)
 Quantification : accurate prediction of surfactant with less than2.5%
 Tranferability : Several instrument uses the same calibration
 Specific design for production lab: no keyboard, barcode reader
fundtionnality, sepcicic sampling box, low cost plastic vial

11. SPOT4LINE
11
Specifications
 Several UV VIS NIR LED : 375,465,525,625,860nm + temperature
sensor
 Multi-parameter capabilities: turbidity 0-10000NTU, liquid
identification in pipe, color monitoring
 Easy and quick to integrate : BN25 clamp or SMS connexion IP 65
 High cleanability
 Software : MODBUS communication (machine) , USB (Computer)
APPLICATIONS :
Cleaning in place
monitoring
 Identification : Direct identification of liquid in pipe
 Quantification : accurate color prediction, mean particle size and
turbidity
 Optimisation of membrane filtration : efficient predition both for
filtrate and concentrate
Current S4L
Water 550 m3 230 m3
Heating (Kw/h) 28 000 14 000
Additive (euros) 795 159
CIP time (h) 1.21 0.75

12. UK,
Phone:
+33 (0)6 61 63 10 13
Richard ESCOTT, PAT Expert
rescott@indatech.eu
Headquarters
Z.A. La Plaine
4 rue Georges Besse
F-34 830 CLAPIERS
FRANCE
Germany, Switzerland, Austria
Kisselweg 10
76646 Bruchsal-Obergrombach
Deutschland
Jérôme MONJUVENT, Sales Engineer
jmonjuvent@indatech.eu
Phone:
+49 (0)176 70 31 93 68
Sales
Arnaud BONET, Sales engineer
+33 (0)7 62 83 59 45
abonet@indatech.eu
Customer service
Yann TURCANT, Technical Manager
+33 (0)4 67 67 97 80
support@indatech.eu
Administration and Invoicing
Cécile FONTANGE
+33 (0)4 67 67 97 80
contact@indatech.eu