Dr. s.veni priya
1
CLASSIFICATION
Based on onset
 Acute.
 Sub-acute.
 Chronic.
Based on type of Exudates
 Serous (Viral, allergic, toxic).
 Catarrhal (allergic – Ropy or thread like thick mucoid
discharge).
 Mucopurulent.
 Purulent.
 Pseudo-Membranous / Membranous.
2
1
2
CLASSIFICATION
(Continued)
Based on Conjunctival Reaction
 Follicular.
 Papillary.
 Granulomatous.
Based on Etiology
 Infectious (Bacterial, Viral, Chlamydial, Fungal and
parasitic).
 Non-infectious (Allergic, Irritants).
3
3
4
RISK FACTORS
Disruption of host defense mechanism caused by:
Dry Eye.
Exposure due to lid retraction, exophthalmos, lagophthalmos
and inadequate blinking.
Nutritional deficiencies / Avitaminosis A.
Local or Systemic Immune Deficiency:
 After topical and systemic immunosuppressive therapy
 Nasolacrimal duct obstruction and infection.
 Radiation damage .
 Trauma.
 Surgery.
 Prior Conjunctival inflammation or infection.
 Systemic Infection.
 Exogenous inoculation
4
1
2
3
4
TYPES OF ACUTE CONJUNCTIVITIS
Bacterial Conjunctivitis:
a. Acute Purulent & Muco Purulent
b. Gonococcal
c. Membraneous & Pseudo Membraneous
d. Angular
Viral – Follicular Conjunctivitis.
Chlamydial – Adult & Neonatal Inclusion Conjunctivitis.
Ophthalmia Neonatorum Conjunctivitis.
5
1
2
3
4
BACTERIAL CONJUNCTIVITIS
Acute Purulent & Muco Purulent
 Etiology
 Contagious
 Transmitted by discharge
 Staph.aureus – most common
 H.aegyptius, N.gonorrhoea.
 Clinical Features
 Hyperaemia
 Mucous discharge
 Stickiness of the lids
 Flakes of mucus & Pus in Fornices and lid margins
 Haloes
 Certain clinical features indicates likelihood of certain specific
infections.
6
BACTERIAL CONJUNCTIVITIS
Acute Purulent & Muco Purulent - Continued
7
BACTERIAL CONJUNCTIVITIS
Acute Purulent & Muco Purulent - Continued
 Treatment
 Topical fluro quinolone – ciprofloxacin, Ofloxacin,
Moxifloxacin, Gatifloxacin.
 Bacitracin or ciprofloxacin Ointment
 Oral antibiotics for patients with pharyngitis and
haemophilus infection in children.
8
BACTERIAL CONJUNCTIVITIS
Gonococcal
 Etiology
 Caused by Neisseria Gonorrhoeae (a bun- shaped
Gram-negative intracellular diplococcus).
 It is sexually transmitted disease
 Clinical Features
 Pre-auricular lymphadenopathy, tenderness and
suppuration.
 No immunity is conferred by an attack.
 Associated systemic signs – Urethritis, rise of
temperature and depression.
9
BACTERIAL CONJUNCTIVITIS
Gonococcal - Continued
 Complications
• Corneal involvement – Gonococcus is capable of
invading the normal cornea through intact cornea.
 Location of Corneal Ulcer – Central, Marginal Ulcer , all
round. Progressing rapidly depth-wise leading to
perforation and complications associated with it.
 Other complications of Gonorrhoeal Conjunctivitis–
Iritis , Iridocyclitis .
 Non Ocular complications – Arthritis, Endocarditis and
Septicaemia.
10
BACTERIAL CONJUNCTIVITIS
Gonococcal - Continued
 Treatment
 Of Gonococcal Conjunctivitis is started on confirmation
ofintracellular Gram-negative diplococci in conjunctival
scrapings in clinically suspected cases.
 Aim of therapy is to prevent or limit the corneal
involvement and to eliminate systemic source.
11
BACTERIAL CONJUNCTIVITIS
Gonoccol - Continued
 Treatment – Continued
 Systemic Treatment
 Ceftriaxone - 1 gm IM , single dose.
 Tetracycline In cases where co-existing Chlamydial
Trachomatis infection is suspected and cases with history of
allergy to Penicillin / Cephalosporins
 Topical Treatment
 Cleanliness
 Ciprofloxacin / Ofloxacin/ Gentamicin/ Tobramycin Eye
Drops 2 hrly.
 Bacitracin Eye Ointment 6 hrly.
 Cycloplegic (Atropine) – in cases of Corneal involvement .
12
BACTERIAL CONJUNCTIVITIS
Membranous & Pseudo Membranous
 Etiology
 Caused by C.diphtheriae, Beta haemolytic strettocci,
H.aegyptius, Staph.aureus & E.coli
 Occurs in children in assosiation with neasels , searlet
fever, influenza & whooting cough.
 Clinical Features
 Swelling of lids
 Eucopurulant discharge
 White Membrane on everting lid
 Great danger of corneal ulcerations – 6 to 10 days.
 Increase risk of symbletharon.
13
BACTERIAL CONJUNCTIVITIS
Membranous & Pseudo Membranous - Continued
 Treatment
 Systemic Treatment
 4,000 to 10,000 units of anti diphtheretic serum.
 Penicillin
 Topical Treatment
 Topical 10,000 units / ml drops made from injectable
preparations.
14
BACTERIAL CONJUNCTIVITIS
Angular
 Etiology
 Caused by Staphylococci and more typically by
Moraxella Lacunata.
 Incubation period is usually 4 days .
 Symptoms - Redness, discomfort, frequent blinking,
sharp pricking pain and mucopurulent discharge.
 Clinical Features
 Congestion limited to intermarginal strip at inner and
outer canthi and neighbouring bulbar conjunctiva.
Excoriation of skin at inner and outer palpabral angles .
15
BACTERIAL CONJUNCTIVITIS
Angular - Continued
 Complications
 Chronic conjunctivitis, Blepheritis, corneal ulcer
(marginal or central associated with hypopyon) .
 Attack does not confer immunity, and relapses may
occur. Swelling of lids.
 Treatment
 Topical Treatment
 Tetracycline eye ointment .
 Eye drops containing Zinc also beneficial, acts by
inhibiting proteolytic ferment.
16
VIRAL CONJUNCTIVITIS
 TYPES
• Acute Follicular Conjunctivitis
• Sub Acute or Chronic Follicular Conjunctivitis
• Epidemic Keroto Conjunctivitis.
• Pharyngo Conjuctival fever.
• Heaymorrhagic Conjunctivitis
• Acute Herpitic Conjunctivitis
• Herps Simplex Conjunctivitis
17
VIRAL CONJUNCTIVITIS
(Continued)
 Clinical Features
 Serous or watery discharge
 Conjunctival foillicals.
 Sub Conjunival haemorrhage
 Punctate epithelial opacities
 Preoricular lymph node.
 Decreased corneal sensation.
 Treatment
 Topical Treatment
 Artificial Tears
 Antibiotic eye drops to prevent secondary infection.
18
OPHTHALMIA NEONATORUM
 Etiology
 Neisseria Gonorrhoeae, Streptococcus Pneumoniae,
Staphylococcus etc.
 Chlamydial Trachomatis, Chalmydial Oculogenitalis
 Chemical Conjunctivitis due to Silver Nitrate 1or 2%
(used as Crede’s method)
 Clinical Features
 Purulent bilateral conjuntival discharge
 Hyper acute blenorrhoea
 Swelling of lids
 Mucopurulent discharge
19
OPHTHALMIA NEONATORUM
(Continued)
 Complications
 Corneal Ulcer : Oval ulcer, just below the centre of
cornea, rarely oval marginal ulcer, progressive ulcer
resulting in – perforation of corneal ulcer, prolapse of
uveal tissue, purulent uveitis, prolapse of lens, prolapse
of vitreous.
 Scarring of cornea, adherent leucoma, anterior
staphyloma, anterior capsular cataract, anophthalmitis.
 Non development of fixation due to corneal opacity
during first 3 weeks.
 Nystagmus due to non-development of macular fixation
20
OPHTHALMIA NEONATORUM
(Continued)
 Treatment
 Systemic Treatment
 Ceftriaxone – 25 to 50 mg/kg single dose.
 Cefatoxine – 100 mg / kg single dose.
 Topical Treatment
 Saline irrigation
 Topical flouro quinolones.
 Topical cycloplejia.
21
ACUTE CONJUNCTIVITIS
22
QUESTION & ANSWER SESSION
Thank you
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Thank you
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Thank you
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Thank you
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acute conj 10.02.16

  • 1.
  • 2.
    CLASSIFICATION Based on onset Acute.  Sub-acute.  Chronic. Based on type of Exudates  Serous (Viral, allergic, toxic).  Catarrhal (allergic – Ropy or thread like thick mucoid discharge).  Mucopurulent.  Purulent.  Pseudo-Membranous / Membranous. 2 1 2
  • 3.
    CLASSIFICATION (Continued) Based on ConjunctivalReaction  Follicular.  Papillary.  Granulomatous. Based on Etiology  Infectious (Bacterial, Viral, Chlamydial, Fungal and parasitic).  Non-infectious (Allergic, Irritants). 3 3 4
  • 4.
    RISK FACTORS Disruption ofhost defense mechanism caused by: Dry Eye. Exposure due to lid retraction, exophthalmos, lagophthalmos and inadequate blinking. Nutritional deficiencies / Avitaminosis A. Local or Systemic Immune Deficiency:  After topical and systemic immunosuppressive therapy  Nasolacrimal duct obstruction and infection.  Radiation damage .  Trauma.  Surgery.  Prior Conjunctival inflammation or infection.  Systemic Infection.  Exogenous inoculation 4 1 2 3 4
  • 5.
    TYPES OF ACUTECONJUNCTIVITIS Bacterial Conjunctivitis: a. Acute Purulent & Muco Purulent b. Gonococcal c. Membraneous & Pseudo Membraneous d. Angular Viral – Follicular Conjunctivitis. Chlamydial – Adult & Neonatal Inclusion Conjunctivitis. Ophthalmia Neonatorum Conjunctivitis. 5 1 2 3 4
  • 6.
    BACTERIAL CONJUNCTIVITIS Acute Purulent& Muco Purulent  Etiology  Contagious  Transmitted by discharge  Staph.aureus – most common  H.aegyptius, N.gonorrhoea.  Clinical Features  Hyperaemia  Mucous discharge  Stickiness of the lids  Flakes of mucus & Pus in Fornices and lid margins  Haloes  Certain clinical features indicates likelihood of certain specific infections. 6
  • 7.
    BACTERIAL CONJUNCTIVITIS Acute Purulent& Muco Purulent - Continued 7
  • 8.
    BACTERIAL CONJUNCTIVITIS Acute Purulent& Muco Purulent - Continued  Treatment  Topical fluro quinolone – ciprofloxacin, Ofloxacin, Moxifloxacin, Gatifloxacin.  Bacitracin or ciprofloxacin Ointment  Oral antibiotics for patients with pharyngitis and haemophilus infection in children. 8
  • 9.
    BACTERIAL CONJUNCTIVITIS Gonococcal  Etiology Caused by Neisseria Gonorrhoeae (a bun- shaped Gram-negative intracellular diplococcus).  It is sexually transmitted disease  Clinical Features  Pre-auricular lymphadenopathy, tenderness and suppuration.  No immunity is conferred by an attack.  Associated systemic signs – Urethritis, rise of temperature and depression. 9
  • 10.
    BACTERIAL CONJUNCTIVITIS Gonococcal -Continued  Complications • Corneal involvement – Gonococcus is capable of invading the normal cornea through intact cornea.  Location of Corneal Ulcer – Central, Marginal Ulcer , all round. Progressing rapidly depth-wise leading to perforation and complications associated with it.  Other complications of Gonorrhoeal Conjunctivitis– Iritis , Iridocyclitis .  Non Ocular complications – Arthritis, Endocarditis and Septicaemia. 10
  • 11.
    BACTERIAL CONJUNCTIVITIS Gonococcal -Continued  Treatment  Of Gonococcal Conjunctivitis is started on confirmation ofintracellular Gram-negative diplococci in conjunctival scrapings in clinically suspected cases.  Aim of therapy is to prevent or limit the corneal involvement and to eliminate systemic source. 11
  • 12.
    BACTERIAL CONJUNCTIVITIS Gonoccol -Continued  Treatment – Continued  Systemic Treatment  Ceftriaxone - 1 gm IM , single dose.  Tetracycline In cases where co-existing Chlamydial Trachomatis infection is suspected and cases with history of allergy to Penicillin / Cephalosporins  Topical Treatment  Cleanliness  Ciprofloxacin / Ofloxacin/ Gentamicin/ Tobramycin Eye Drops 2 hrly.  Bacitracin Eye Ointment 6 hrly.  Cycloplegic (Atropine) – in cases of Corneal involvement . 12
  • 13.
    BACTERIAL CONJUNCTIVITIS Membranous &Pseudo Membranous  Etiology  Caused by C.diphtheriae, Beta haemolytic strettocci, H.aegyptius, Staph.aureus & E.coli  Occurs in children in assosiation with neasels , searlet fever, influenza & whooting cough.  Clinical Features  Swelling of lids  Eucopurulant discharge  White Membrane on everting lid  Great danger of corneal ulcerations – 6 to 10 days.  Increase risk of symbletharon. 13
  • 14.
    BACTERIAL CONJUNCTIVITIS Membranous &Pseudo Membranous - Continued  Treatment  Systemic Treatment  4,000 to 10,000 units of anti diphtheretic serum.  Penicillin  Topical Treatment  Topical 10,000 units / ml drops made from injectable preparations. 14
  • 15.
    BACTERIAL CONJUNCTIVITIS Angular  Etiology Caused by Staphylococci and more typically by Moraxella Lacunata.  Incubation period is usually 4 days .  Symptoms - Redness, discomfort, frequent blinking, sharp pricking pain and mucopurulent discharge.  Clinical Features  Congestion limited to intermarginal strip at inner and outer canthi and neighbouring bulbar conjunctiva. Excoriation of skin at inner and outer palpabral angles . 15
  • 16.
    BACTERIAL CONJUNCTIVITIS Angular -Continued  Complications  Chronic conjunctivitis, Blepheritis, corneal ulcer (marginal or central associated with hypopyon) .  Attack does not confer immunity, and relapses may occur. Swelling of lids.  Treatment  Topical Treatment  Tetracycline eye ointment .  Eye drops containing Zinc also beneficial, acts by inhibiting proteolytic ferment. 16
  • 17.
    VIRAL CONJUNCTIVITIS  TYPES •Acute Follicular Conjunctivitis • Sub Acute or Chronic Follicular Conjunctivitis • Epidemic Keroto Conjunctivitis. • Pharyngo Conjuctival fever. • Heaymorrhagic Conjunctivitis • Acute Herpitic Conjunctivitis • Herps Simplex Conjunctivitis 17
  • 18.
    VIRAL CONJUNCTIVITIS (Continued)  ClinicalFeatures  Serous or watery discharge  Conjunctival foillicals.  Sub Conjunival haemorrhage  Punctate epithelial opacities  Preoricular lymph node.  Decreased corneal sensation.  Treatment  Topical Treatment  Artificial Tears  Antibiotic eye drops to prevent secondary infection. 18
  • 19.
    OPHTHALMIA NEONATORUM  Etiology Neisseria Gonorrhoeae, Streptococcus Pneumoniae, Staphylococcus etc.  Chlamydial Trachomatis, Chalmydial Oculogenitalis  Chemical Conjunctivitis due to Silver Nitrate 1or 2% (used as Crede’s method)  Clinical Features  Purulent bilateral conjuntival discharge  Hyper acute blenorrhoea  Swelling of lids  Mucopurulent discharge 19
  • 20.
    OPHTHALMIA NEONATORUM (Continued)  Complications Corneal Ulcer : Oval ulcer, just below the centre of cornea, rarely oval marginal ulcer, progressive ulcer resulting in – perforation of corneal ulcer, prolapse of uveal tissue, purulent uveitis, prolapse of lens, prolapse of vitreous.  Scarring of cornea, adherent leucoma, anterior staphyloma, anterior capsular cataract, anophthalmitis.  Non development of fixation due to corneal opacity during first 3 weeks.  Nystagmus due to non-development of macular fixation 20
  • 21.
    OPHTHALMIA NEONATORUM (Continued)  Treatment Systemic Treatment  Ceftriaxone – 25 to 50 mg/kg single dose.  Cefatoxine – 100 mg / kg single dose.  Topical Treatment  Saline irrigation  Topical flouro quinolones.  Topical cycloplejia. 21
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  • 24.
  • 25.
  • 26.