The document discusses various types of abortion including spontaneous, induced, threatened, inevitable, complete, incomplete, missed, and septic abortion. It defines each type, describes their signs and symptoms, causes, investigations, and management. Spontaneous abortions occur in approximately 20% of pregnancies while 80% are terminated by induction within 2-5 months of gestation. Threatened abortion involves bleeding with no cervical changes, inevitable abortion has progressed bleeding with cervical changes, and missed abortion is a silent miscarriage with fetal demise but retained placenta. Management involves evacuation/dilatation and curettage, antibiotics, and controlling hemorrhage depending on the abortion type and gestational age.
Abortion - Presented By Mohammed Haroon Rashid Haroon Rashid
Subject - Medical Surgical Nursing - II , Topic - Abortion, Presented by Mohammed Haroon Rashid, Basic B.Sc Nursing 3rd Year in Florence College Of Nursing
Abortion - Presented By Mohammed Haroon Rashid Haroon Rashid
Subject - Medical Surgical Nursing - II , Topic - Abortion, Presented by Mohammed Haroon Rashid, Basic B.Sc Nursing 3rd Year in Florence College Of Nursing
A condition in which the volume of amniotic fluid exceeds 2000ml during the last half of pregnancy.Clinical DefinationAmniotic fluid index more than 25cm for gestational age.
vertical pocket more than 8cm ( normal vertical pocket 2 to 8 cm)
AFI - It measure sonographocally by dividing abdomen in four quadrants and calculate the distance of each quadrant from umbilicus to peripheral point.
Normal AFI = 5 to 25 cm
Causes
Fetal anomalies(20%)
I) Twin to twin transfusion syndrome
(II) Ancephalophaly( in 50% cases)
(iii) Open spina bifida
(Iv) Esophageal or Duodenal Atresia
(v) Facial cleft and neck massess
(vi) Hydrops Fetalis
(vii) Aneuploidy
. placental anomolies
3. MULTIPLE PREGNANCY
Types
Acute polyhydromnias Develop suddenly by a rapid increase in volume, between 20 to 24 week's of gestation.
A condition in which the volume of amniotic fluid exceeds 2000ml during the last half of pregnancy.Clinical DefinationAmniotic fluid index more than 25cm for gestational age.
vertical pocket more than 8cm ( normal vertical pocket 2 to 8 cm)
AFI - It measure sonographocally by dividing abdomen in four quadrants and calculate the distance of each quadrant from umbilicus to peripheral point.
Normal AFI = 5 to 25 cm
Causes
Fetal anomalies(20%)
I) Twin to twin transfusion syndrome
(II) Ancephalophaly( in 50% cases)
(iii) Open spina bifida
(Iv) Esophageal or Duodenal Atresia
(v) Facial cleft and neck massess
(vi) Hydrops Fetalis
(vii) Aneuploidy
. placental anomolies
3. MULTIPLE PREGNANCY
Types
Acute polyhydromnias Develop suddenly by a rapid increase in volume, between 20 to 24 week's of gestation.
It is the expulsion or extraction from its mother of an embryo or fetus weighing 500 gm or less when it is not capable of independent survival (WHO).
The 500gm of fetal development is attained approximately at 22 weeks of gestation.
Expelled fetus- Abortus
complcations of third stage of labour, includes PPH, Inversion of uterus, retained placenta, placenta accreta, increta, percreta, amniotic fluid embolism
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
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New Drug Discovery and Development .....NEHA GUPTA
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micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
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Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
1. Abortion
Prepared By : Syed Hassnain Shah
Group # 02
Semester # 07
Submitted to : Dr. Kahkashan
2. Any bleeding in pregnancy is
abnormal. It is also known as
haemorrhage in early
pregnancy.
The term miscarriage and
abortion are synonymous.
3. The expulsion or extraction of the fetus or
embryo from the uterus weighing less than
1000gm is called abortion.
OR
Termination of pregnancy before 28wks. Of
gestation or before the period of viability
either spontaneously or by induction is called
abortion
5. Approximately 20% of all
pregnancies are terminated
spontaneously and 80% are
terminated by induction with in
2- 5 months of gestation.
6. Spontaneous abortion is defined
as the involuntary loss of the
products of conception prior to
28 weeks of gestation, when the
fetus weighs approximately 1,000
gm or less.
7. Maternal cause.
Structural abnormalities of the genital organ
such as retroversion of uterus, bicornuate
uterus and fibroids.
Maternal Infections such as rubella, UTI,
hyperpyrexia, hepatitis.
Medical condition such as diabetes, renal
disease and thyroid dysfunction, when not
well controlled.
Genetic factor.
8. Immunological factor- placental infarction,
placental thrombosis.
Blood group incompatibility
Drugs- antimalarial, antipsychotic,
anticonvulsant drugs.
Environmental factors- excessive consumption
of alcohol & smoking
Lack of iron & vitamin in diet.
Exposure to radiation
10. 1.Threatened abortion-
It is a clinical entity where the process of abortion has
started but has not progressed to a state from which
the recovery is impossible.
Signs & symptoms-
Amenorrhea more than 6 wks.
it is an abortion characterized by vaginal bleeding
with or without uterine contraction.
The blood loss may be scanty with or without
accompanying backache and cramp like
pain(resembling dysmenorrhoea).
11.
12. The cervix and uterus feels soft
Os may be closed, and blood seen in the
external os.
The outcome of a threatened abortion
could be either stoppage of bleeding by
management and continuation of
pregnancy to term.
continuation of bleeding and uterine
contraction to expel the products of
conception if not treated.
13. Blood- HB estimation, ABO & RH
factor, cross match, VDRL, HIV, torch
test, thyroid function test.
USG- sometimes a blood clot may be
seen around the gestational sac.
Urine test- UPT is always +ve. Culture
test, sugar & albumin .
14. 1. complete bed rest
2. drugs- hormonal supportive therapy-
HCG 5000 IU ( inj. Proluton 500mg(2ml)
deep I/M twice a week)
Sedative- T. phenobarb- 30mg HS
T. diazepam 5 mg bd
Laxative- milk of mag or cremaffin 2tsf- HS
enema should be avoided.
15. Advice the woman to Preserve all the vulval pads to
observe amount of bleeding.
Anything is expelled out from the vagina should be
reported immediately.
Note the vital signs.
If bleeding & abdominal pains is aggravated should
be reported immediately.
Advice patient should limit her activities at least 2
wks.
Avoid heavy weight lifting
Avoid unnecessary journey
Coitus should be avoided in this period
16. 2. Inevitable abortion-
It is a clinical type of abortion where the changes
have progressed to a state from where
continuation of pregnancy is impossible.
Signs & symptoms-
In this type of abortion the women present with
bleeding, often heavy, with clots or products of
conception.
The vaginal examination cervix feels soft, os is
open & blood clot may be seen in the vagina or
protruding through the os.
17. ↑ pain in the lower abdomen which may
be colicky or like labour pains
Cervical dilatation & uterine contraction
are present
Patient may look pallor due to blood loss
Tachycardia, hypotension, cold &
clammy extrimities, patient may go in
shock.
Investigations- HB%, bloodgroup, RH
factor, USG.
18. If pregnancy is less than 12 wks. S/E is done
Intravenous fluids & blood transfusion to treat
shock.
If pregnancy is more than 12 wks. Tab.
Misoprost 400 µg p/v or Inj. Oxytocin 20 unit
with 5% dext. Should be given for spontaneous
expulsion.
If fetus is expelled out & placenta is retained
should be removed by D&C.
Inj. T.T should be given
19. If mother is RH-ve than Anti-D 50-
150 µmg. I/M given.
If bleeding is excessive should be
controlled by administering inj.
Methargin (0.2mg) or
inj. Prostadin 250 mg I/M.
20. 3 . Complete abortion –
when the products of conception is expelled
Completely from the uterus & the uterine
cavity is empty it is called complete abotion.
S/S- decreased amount of vaginal bleeding &
lower abdominal pain.
- Uterus is smaller than the period of
amenorrhea.
- Cervical os is closed .
22. 4. Incomplete abortion-
When the entire products of conception are
partialy expelled and some products are left
inside the uterine cavity is called incomplete
abotion.
S/S- continous and profuse vaginal bleeding
Lower abdominal pain
Pallor and signs of shock
Internal os is open
Uterus feels soft, smaller than the period of
amenorrhea.
23. If pregnancy is less than 12 wks. S/E done.
If pregnancy is more than 12 wks. I/V oxytocin 20
unit may be given for spontaneous expulsion
If fetus is expelled & placenta is retained should be
removed by D&C. if placenta is not separated than
S/E is done under G.A
Inj. Morphine 15 mg should be given before S/E.
inj.T.T, antibiotic should be given before D&C
Excessive bleeding may be controlled by
administering inj. Methergin/ prostadin or tab.
Misoprost 200µg P/R
24. 5. Missed abortion-
This is also known as silent miscarriage
The embryo dies despite the presence
of viable placenta and retained inside
of the uterus
Death of the embryo occurs but the
mothers body fails to recognize the
demise.
25. H/O brownish vaginal discharge or spotting
Retrogression of breast changes
Ceasation of uterine growth
FHS may not be audible (after 20 wks.) in late
pregnancy
Cervix feels firm, internal os closed
↓fetal movement in late pregnancy
Uterus size is smaller than period of gestation
26. UPT- becomes –ve
USG- reveals absence of FHS
X-ray- shows patchy skeletal
shadows
Blood- B.T,C.T, platelet count, HB
should be done
27. If pregnancy is less than 12 wks.- D&C/ S&E
of uterine cavity under G.A
Antibiotic should be given without delay
If more than 12 wks.- induction is done by
oxytocin (10-20 unit with 5%D) at the rate of
30 drops/min
Prostaglandin ( tab. misoprost/carboprost)
should be given for cervical dilatation
28. Occurrence of spontaneous abortion in 3 or more
successive pregnancy is called recurrent of
habitual abortion, it may be occur in first or
second trimester
Causes-
maternal diseases- syphilis, diabetes, chronic
nephritis, hypertension, RH incompatibility,
metritis, TORCH test is +ve
Progestrone defficiency- luteal phase defect
29. Blood group & Rh factor.
HB, complete blood count.
Urine- routine, microscopic & culture.
Glucose tolerance test.
Liver, thyroid, renal function test.
TORCH test.
Cervical swab culture.
USG, hysterosalpingogram- to visualize the uterus &
fallopian tube for any infection.
30. Systemic illness should be treated promptly
Hormonal therapy is useful in case of luteal defects.
The patient should be advice for adequate rest &
appropriate diet
In case of cervical incompetence cervical encircling
should be done between 3- 4 month of pregnancy (
this operation is called shirodkar suture/ macdonald
suture)
At the time of delivery(37- 38wks.)this suture is cut
to allow the vaginal delivery.
31. 7. Septic abortion- characterized by infection
of the products of conception in uterus, this
condition is mostly common in induced or
incomplete abortion, some illegal abortion
carried out in non- sterile conditions often lead to
septic abortion.
C/M- pyrexia 100.4 & above chills with rigor
c/o vomiting & diarrohea
Abdominal pain
Foul smelling vaginal discharge which is often
purulent
Vaginal bleeding with products of conception
32. Pallor & sweating
Tachycardia and ↓ B.P
Abdominal distension and tenderness
Signs of toxemia
Clinical grading of infection-
Grade-I- localized in the uterus- involves
endometrium & myometrium
Grade-II- infection spread beyond the uterus,
tubes, ovaries & pelvic structure also.
Grade-III- generalized peritonitis or endotoxic
shock, jaundice & acute renal failure.
34. Hemorrhage
Injury may occur to uterus & other
organs
Peritonitis
Perforation of the uterus
Endotoxic shock
Acute renal failure
thrombophlebitis
35. Hospitalized the patient- start I/V fluids
Broad spectrum antibiotics I/V should be started
Take high vaginal swab & blood culture for
investigations
If pelvic abscess is present should be drain out
Vital signs should be monitored- if pyrexia
should be treated with antipyretic
Strict I/O charting
Uterus should be evacuated to remove the source
of infection