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International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 03 | Mar 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 1288
A New Real Time Clinical Decision Support System Using Machine
Learning for Critical Care Unit
D. GAYATHRI1, BOLLINENI SANDEEP SAI2, CHILAKA VENKATA MOHITH3
1Assistant Professor, Department of Computer Science and Engineering, SCSVMV, Kanchipuram
2B.E Graduate (IV year), Department of Computer Science and Engineering, SCSVMV, Kanchipuram
3B.E Graduate (IV year), Department of Computer Science and Engineering, SCSVMV, Kanchipuram
----------------------------------------------------------------------***---------------------------------------------------------------------
Abstract: - In intensive care units, mean arterial pressure
(MAP) is a key clinical measure for estimating the health of
critically ill patients. As a result, real-time clinical decisions
support systems that detect irregularities and diversions in
Chart can assist prevent major consequences by intervening
early. At the bedside, state-of-the-art decisionsupportsystems
are built on a three-phase systemthatincludesofflinetraining,
transfer literacy, and retraining. With imprisonment and
journey, their relationship in critical care units is difficult.
Using a new machine literacy structure, we offer a real-time
clinical decision assistance system vaticinating the Chart
status at the bedside in this composition. Thesuggestedsystem
operates in real time at the bedside, eliminating the need for
an offline training phase with big datasets. There are two
levels to the proposed machine literacy framework. Stage I
uses hierarchical temporal memory (HTM)andonlineliteracy
to enable real-time data processing and unsupervised
prognostications. This is the first time it's been used on
medical signals, to the best of our knowledge. Stage II is a long
short-term memory (LSTM) classifier that predicts the status
of the case's Chart in advance based on Stage I stream
forecasts. We assess the proposed system's performance
thoroughly and compare it to state-of-the-artsystemsthatuse
logistic retrogression (LR). The proposed system beats LR in
terms of bracket delicacy, recall, perfection, and area under
the receiver operation wind, according to the comparison
(AUROC).
Keywords: Critical care, feature extraction, machine
learning.
1. INTRODUCTION
The intensive care unit (ICU) is a hospital that specialises in
treating critically ill patients who require life-saving
therapies. Many forerunners of the ultramodern ICU were
developed in the late 1950s to provide respiratory support
during a polio epidemic; many forerunners of the
ultramodern ICU were established in the late 1950s to
provide respiratory support duringa polioepidemic.Studies
have revealed that ICUs had a lower rate of mortality, a
shorter duration of stay in the hospital, and fewer sickness
complicationsthanothersanitariumdepartments,validating
the efficacy of the fierce monitoring technique. Nonetheless,
real-world limits limit the number of nursers and croakers
assigned to ICU cases. The number of sanitarium beds in the
United States decreased by 4.2 between 2000 and 2005,
although critical care beds climbed by 6.5, and residency
increased by 4.5.
A medical surroundings in which data reliance comes to the
fore is the critical care department (CCD) in any of its
general or technical forms ferocious care unit (ICU),surgical
ferocious care units (SICU), neonatal ferocious care unit
(NICU), or pediatric ferocious care unit (PICU), is has
practical counteraccusations for the useofMDSSatthepoint
of care (7). As egregious as it may feel to say, the ICU cares
for acutely ill cases. Numerous of these, and particularly
SICU cases, are technologically dependent on life-sustaining
bias similar as infusion pumps, mechanical ventilators,
catheters, etc. Besides treatment, the assessment of
prognostic in critical care and case stratifcation combining
miscellaneous data sources are extremely important in a
terrain similar as this, which is so fully centered on the case.
CCD conditions obviously put a strain on data accession and
operation tasks. To evaluation of clinical requirements may
change depending on the perceptivity of the case and on the
being conditions at the point of care. The type and volume of
data captured by the bedside attestation are conditioned by
changes in patient status, either through paper and
electronic records, or flow wastes. It may also be necessary
to include farther electronic health record and monitoring
bias data. These may include, amongstothers,fluidinputand
patient affair, laboratory blood draw analysis, medical
images, demographics, and so on.
1.1 Scope of the Project:
In critical care units, it's essential to prognosticate adverse
events as it allows for preventative interventions and
reduces clinical complications. Occurrences of anomalous
mean arterial pressure
(Chart) values are frequent at the bedside as they're
frequently associated with anesthesia. These occurrences
are linked to cardiovascular pitfalls, multiple organ failure,
and life- hanging complications, especially in critically ill
cases. The use of machineliteracyinclinical decisionsupport
systems has come a current exploration hotspot. These
systems are grounded on offline analysis to save the
challenge of processing aqueducts in real time.
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 03 | Mar 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 1289
1.2 Literature Survey:
Digital access to data has revolutionized ways of doing
wisdom in the natural and biomedical fields. In recent
decades, there has been a major shift in the way
experimenters process and understand scientific data.
Digital access to data has revolutionized ways of doing
wisdom in the natural and biomedical fields, leading to a
data-ferocious approach to exploration that uses innovative
styles to produce, store, distribute, and interpret huge
quantities of data. Leonelli is the first scholar to use a study
of contemporary data-ferocious wisdom to give a
philosophical analysis of the epistemology of data.
A composition in Nature moment outlines the challengesof
handling large volumes of data in biology. A composition in
Nature moment outlines the challenges of handling large
volumes of data in biology. It describes ELIXIR as"a design to
help scientists across Europe safeguard and partake their
data, and to support being coffers similar as databases and
calculating installations in individual countries. Whereas
CERN has one supercollider producing data in one position,
natural exploration generating high volumes of data is
distributed across numerous labs pressing the need to
partake coffers."
The goal of this study is to look at past and current medical
decision support systems, as well as the terrain in which
they operate, and to suggest particular research paths that
will improve the integration and relinquishment of these
systems in today's health care systems. Medical decision
support tools were mostly developed from a specialist
capability standpoint, and this viewpointhashamperednew
development and integration of these critical technologies
into patient operation work flows and clinical information
systems. Clinical decision support faces significant hurdles.
High-quality, effective methods for planning, producing,
presenting, and implementing patients with co-morbidities
are urgently needed.
2. PROJECT DESCRIPTION:
This review has epitomized the rearmost trends in machine
literacy in critical care. Focus has been given to all factors
necessary in this field accession of data,assuranceofquality,
and final analysis. A large quantum of trouble has been
invested in the processing and confirmationofdata acquired
within the ICU. Numerous of these styles are necessary due
to the fairly unique format of data collection in the ICU.
When developing algorithms in other disciplines, similar as
aircraft health monitoring or finance, experimenters will
specifically collect data for the purpose of analysis. Still,
utmost operations of machine literacy in the ICU are
secondary, that is, the data is collected for a purpose other
than for the proposed. Constantly, the data collected is
acquired during routine clinical care wheretherearelittle to
no impulses for accession of accurate data. Infact,thosewho
record the data are constantly averted from auditing and
correcting the compliances due to extreme time constraints.
2.1 Problem Statement:
Edward Labs has developed an LR- grounded model of
real- time hypotension vatic nation grounded on
waveform analysis in. LR was also used to calculate the
reliance between hypertensive events and acute order
injury in and diastolic and systolic blood pressure in.
Colorful logical tools are presently used in clinical
practice to support decision- making on colorful clinical
parameters, including Chart. These clinical decision-
making tools substantially employ machine literacy ways
using algorithms similar as LR, arbitrary timber (RF),
supported vector machine (SVM), and deep literacy.
Several studies have been performed on the early
identification of events with blood pressure and
supporting opinions.
2.2 Proposed Method:
The suggested system works in real time at the bedside,
eliminating the need for an offline training phase with big
datasets. As a result, timely actions and better healthcare
services are possible. There are two steps to the
suggested machine learning structure. Stage I uses
hierarchical temporal memory (HTM) and online learning
to enable real-time stream processing and deliver
unsupervised predictions. This is the first time it has been
applied to medical signals, to the best of our knowledge.
Stage II is a long short-term memory (LSTM) classifier
that uses Stage I stream predictions to forecast the
patient's MAP status ahead of time.
1. We assess the proposed system's performance and
compare it to current state-of-the-art systems that use
logistic regression (LR).
In terms of classification accuracy, recall, precision, and
area under the receiver operation curve, the suggested
system surpasses LR (AUROC).
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 03 | Mar 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 1290
Architecture:
Re-train algorithm
Train MI
Process
2.3 Modules Description:
 Upload dataset
Using this module dataset is uploaded.
 preprocess dataset
Using this module preprocess for data take
Place.
 Feature selection
Using this module data is loaded.
 DTRF GNB KNN
Using this module data analysis takes place.
 Predicting With Model
Using this module prediction model is build.
 Input Tokenization
Using this module input data is read.
 Based On ML Types
Using this module machine learning model
Generated.
 Prediction
Using this module predication take place.
 Display the Result
It display result on screen
Algorithm:
DecisionTree:
Each Machine Learning algorithm has its own set of
advantages and reasons for being implemented. One such
widely used algorithm is the decision tree algorithm. A
decision tree is a type of upside-down tree that makes
decisions based on the data conditions. The question now
is, why use a decision tree? Why not use different
algorithms? The reason is simple: when the data is
primarily categorical and dependent on circumstances,
the decision tree produces outstanding results. Is it still
perplexing you? Let's have a look at an example to make
things clearer. Let's start with a dataset and presume
we're going to use a decision tree to develop our final
model. As a result, the algorithm will create a decision
tree internally.
RandomForest:
The supervised literacy system is used by Random Forest,
a well- known machine literacy algorithm. It can be used
for both bracket and retrogression problems in machine
literacy. It's grounded on ensemble literacy, which is a
fashion for combining multiple classifiers to attack a
complex problem and ameliorate the model's
performance. According to the name, "Random Forest is a
classifier that contains a number of decision trees on
colorful subsets of a given dataset and takes the average
to boost the dataset's projected delicacy."The arbitrary
timber collects vaticinations from each tree and predicts
the final affair grounded on the maturity votes of
protrusions, rather than depending on a single decision
tree.
NaiveBayes:
Naive Bayes is a classification technique based on Bayes'
theorem that naively assumes feature independence and
assigns all characteristics in a dataset the same weight
(degree of importance). As a result, the approach is based
on the assumption that no one feature in a dataset is
linked to or influences another.
KNearestNeighbour:
The K-Nearest Neighbour algorithm is predicated on the
Supervised Learning technique and is one among the
foremost basic Machine Learning algorithms. The K-NN
method assumes that the new case/data and existing
cases are similar and places the new case within the
category that's most almost like the prevailing categories.
The K-NN method stores all available data and classifies a
replacement datum supported its similarity to the
prevailing data. This means that new data are often
quickly sorted into a well-defined category using the K-NN
method. The K-NN approach can be used for both
regression and classification, but it is more commonly
utilized for classification tasks.
Training Data
D
Training MI
Algorithm
New Input
Data
Prediction
False Result
Correct
Output
Result
International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056
Volume: 09 Issue: 03 | Mar 2022 www.irjet.net p-ISSN: 2395-0072
© 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 1291
3. CONCLUSIONS:
This paper offers a novel personalized real-time decision-
making support system based on a hybrid prediction-
and-classification machine learning system. Because it
runs directly at the bedside, the suggested system is
considered a breakthrough when compared to state-of-
the-art real-time systems using three phase-based
models. It eliminates the need for substantial offline
modeling, unpredictability, and delays that come with
traditional systems.
The suggested novel machine learning architecture
consists of two stages: a hierarchical temporal memory
(HTM) predictor stage, which was first applied to medical
signals, and an LSTM classifier.
REFERENCES
 Leonelli S. Data-centric biology: a philosophical
study. Chicago: University of Chicago Press; 2016.
 Marx V. Biology: The big challenges of Big Data.
Nature. 2013; 498(7453):255–60.
 Fieschi M, Dufour JC, Staccini P, Gouvernet J,
Bouhaddou O. Medical Decision Support Systems:
old dilemmas and new paradigms. Method Inform
Med. 2003;42(3):190–8.
 Bates DW, Kuperman GJ, Wang S, Gandhi T, Kittler
A, Volk L, Spurr C, Khorasani R, Tanasijevic M,
Middleton B. Ten commandments for efective
clinical decision support: making the practice of
evidence-based medicine a reality.JAmMedInform
Assoc. 2003;10(6):523–30.
 Sittig DF, Wright A, Osherof JA, Middleton B, Teich
JM, Ash JS, Campbell E, Bates DW. Grand challenges
in clinical decision support. J Biomed Inform.
2008;41(2):387–92.
BIOGRAPHIES
 Ms. D. Gayathri is an Assistant Professor in
Computer Science and Engineering Sri
Chandrasekharendra Saraswathi Viswa
Mahavidyalaya deemed to be university, Enathur,
Kanchipuram, India.
 Mr. Bollineni Sandeep Sai, Student, B.E. Computer
Science and Engineering, Sri Chandrasekharendra
Saraswathi Viswa Mahavidyalaya deemed to be
university, Enathur, Kanchipuram, India.
 Mr. Chilaka Venkata Mohith, Student,B.E.Computer
Science and Engineering, Sri Chandrasekharendra
SarswathiViswa Mahavidyalaya deemed to be
university, Enathur, Kanchipuram, India.

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A New Real Time Clinical Decision Support System Using Machine Learning for Critical Care Unit

  • 1. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 03 | Mar 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 1288 A New Real Time Clinical Decision Support System Using Machine Learning for Critical Care Unit D. GAYATHRI1, BOLLINENI SANDEEP SAI2, CHILAKA VENKATA MOHITH3 1Assistant Professor, Department of Computer Science and Engineering, SCSVMV, Kanchipuram 2B.E Graduate (IV year), Department of Computer Science and Engineering, SCSVMV, Kanchipuram 3B.E Graduate (IV year), Department of Computer Science and Engineering, SCSVMV, Kanchipuram ----------------------------------------------------------------------***--------------------------------------------------------------------- Abstract: - In intensive care units, mean arterial pressure (MAP) is a key clinical measure for estimating the health of critically ill patients. As a result, real-time clinical decisions support systems that detect irregularities and diversions in Chart can assist prevent major consequences by intervening early. At the bedside, state-of-the-art decisionsupportsystems are built on a three-phase systemthatincludesofflinetraining, transfer literacy, and retraining. With imprisonment and journey, their relationship in critical care units is difficult. Using a new machine literacy structure, we offer a real-time clinical decision assistance system vaticinating the Chart status at the bedside in this composition. Thesuggestedsystem operates in real time at the bedside, eliminating the need for an offline training phase with big datasets. There are two levels to the proposed machine literacy framework. Stage I uses hierarchical temporal memory (HTM)andonlineliteracy to enable real-time data processing and unsupervised prognostications. This is the first time it's been used on medical signals, to the best of our knowledge. Stage II is a long short-term memory (LSTM) classifier that predicts the status of the case's Chart in advance based on Stage I stream forecasts. We assess the proposed system's performance thoroughly and compare it to state-of-the-artsystemsthatuse logistic retrogression (LR). The proposed system beats LR in terms of bracket delicacy, recall, perfection, and area under the receiver operation wind, according to the comparison (AUROC). Keywords: Critical care, feature extraction, machine learning. 1. INTRODUCTION The intensive care unit (ICU) is a hospital that specialises in treating critically ill patients who require life-saving therapies. Many forerunners of the ultramodern ICU were developed in the late 1950s to provide respiratory support during a polio epidemic; many forerunners of the ultramodern ICU were established in the late 1950s to provide respiratory support duringa polioepidemic.Studies have revealed that ICUs had a lower rate of mortality, a shorter duration of stay in the hospital, and fewer sickness complicationsthanothersanitariumdepartments,validating the efficacy of the fierce monitoring technique. Nonetheless, real-world limits limit the number of nursers and croakers assigned to ICU cases. The number of sanitarium beds in the United States decreased by 4.2 between 2000 and 2005, although critical care beds climbed by 6.5, and residency increased by 4.5. A medical surroundings in which data reliance comes to the fore is the critical care department (CCD) in any of its general or technical forms ferocious care unit (ICU),surgical ferocious care units (SICU), neonatal ferocious care unit (NICU), or pediatric ferocious care unit (PICU), is has practical counteraccusations for the useofMDSSatthepoint of care (7). As egregious as it may feel to say, the ICU cares for acutely ill cases. Numerous of these, and particularly SICU cases, are technologically dependent on life-sustaining bias similar as infusion pumps, mechanical ventilators, catheters, etc. Besides treatment, the assessment of prognostic in critical care and case stratifcation combining miscellaneous data sources are extremely important in a terrain similar as this, which is so fully centered on the case. CCD conditions obviously put a strain on data accession and operation tasks. To evaluation of clinical requirements may change depending on the perceptivity of the case and on the being conditions at the point of care. The type and volume of data captured by the bedside attestation are conditioned by changes in patient status, either through paper and electronic records, or flow wastes. It may also be necessary to include farther electronic health record and monitoring bias data. These may include, amongstothers,fluidinputand patient affair, laboratory blood draw analysis, medical images, demographics, and so on. 1.1 Scope of the Project: In critical care units, it's essential to prognosticate adverse events as it allows for preventative interventions and reduces clinical complications. Occurrences of anomalous mean arterial pressure (Chart) values are frequent at the bedside as they're frequently associated with anesthesia. These occurrences are linked to cardiovascular pitfalls, multiple organ failure, and life- hanging complications, especially in critically ill cases. The use of machineliteracyinclinical decisionsupport systems has come a current exploration hotspot. These systems are grounded on offline analysis to save the challenge of processing aqueducts in real time.
  • 2. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 03 | Mar 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 1289 1.2 Literature Survey: Digital access to data has revolutionized ways of doing wisdom in the natural and biomedical fields. In recent decades, there has been a major shift in the way experimenters process and understand scientific data. Digital access to data has revolutionized ways of doing wisdom in the natural and biomedical fields, leading to a data-ferocious approach to exploration that uses innovative styles to produce, store, distribute, and interpret huge quantities of data. Leonelli is the first scholar to use a study of contemporary data-ferocious wisdom to give a philosophical analysis of the epistemology of data. A composition in Nature moment outlines the challengesof handling large volumes of data in biology. A composition in Nature moment outlines the challenges of handling large volumes of data in biology. It describes ELIXIR as"a design to help scientists across Europe safeguard and partake their data, and to support being coffers similar as databases and calculating installations in individual countries. Whereas CERN has one supercollider producing data in one position, natural exploration generating high volumes of data is distributed across numerous labs pressing the need to partake coffers." The goal of this study is to look at past and current medical decision support systems, as well as the terrain in which they operate, and to suggest particular research paths that will improve the integration and relinquishment of these systems in today's health care systems. Medical decision support tools were mostly developed from a specialist capability standpoint, and this viewpointhashamperednew development and integration of these critical technologies into patient operation work flows and clinical information systems. Clinical decision support faces significant hurdles. High-quality, effective methods for planning, producing, presenting, and implementing patients with co-morbidities are urgently needed. 2. PROJECT DESCRIPTION: This review has epitomized the rearmost trends in machine literacy in critical care. Focus has been given to all factors necessary in this field accession of data,assuranceofquality, and final analysis. A large quantum of trouble has been invested in the processing and confirmationofdata acquired within the ICU. Numerous of these styles are necessary due to the fairly unique format of data collection in the ICU. When developing algorithms in other disciplines, similar as aircraft health monitoring or finance, experimenters will specifically collect data for the purpose of analysis. Still, utmost operations of machine literacy in the ICU are secondary, that is, the data is collected for a purpose other than for the proposed. Constantly, the data collected is acquired during routine clinical care wheretherearelittle to no impulses for accession of accurate data. Infact,thosewho record the data are constantly averted from auditing and correcting the compliances due to extreme time constraints. 2.1 Problem Statement: Edward Labs has developed an LR- grounded model of real- time hypotension vatic nation grounded on waveform analysis in. LR was also used to calculate the reliance between hypertensive events and acute order injury in and diastolic and systolic blood pressure in. Colorful logical tools are presently used in clinical practice to support decision- making on colorful clinical parameters, including Chart. These clinical decision- making tools substantially employ machine literacy ways using algorithms similar as LR, arbitrary timber (RF), supported vector machine (SVM), and deep literacy. Several studies have been performed on the early identification of events with blood pressure and supporting opinions. 2.2 Proposed Method: The suggested system works in real time at the bedside, eliminating the need for an offline training phase with big datasets. As a result, timely actions and better healthcare services are possible. There are two steps to the suggested machine learning structure. Stage I uses hierarchical temporal memory (HTM) and online learning to enable real-time stream processing and deliver unsupervised predictions. This is the first time it has been applied to medical signals, to the best of our knowledge. Stage II is a long short-term memory (LSTM) classifier that uses Stage I stream predictions to forecast the patient's MAP status ahead of time. 1. We assess the proposed system's performance and compare it to current state-of-the-art systems that use logistic regression (LR). In terms of classification accuracy, recall, precision, and area under the receiver operation curve, the suggested system surpasses LR (AUROC).
  • 3. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 03 | Mar 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 1290 Architecture: Re-train algorithm Train MI Process 2.3 Modules Description:  Upload dataset Using this module dataset is uploaded.  preprocess dataset Using this module preprocess for data take Place.  Feature selection Using this module data is loaded.  DTRF GNB KNN Using this module data analysis takes place.  Predicting With Model Using this module prediction model is build.  Input Tokenization Using this module input data is read.  Based On ML Types Using this module machine learning model Generated.  Prediction Using this module predication take place.  Display the Result It display result on screen Algorithm: DecisionTree: Each Machine Learning algorithm has its own set of advantages and reasons for being implemented. One such widely used algorithm is the decision tree algorithm. A decision tree is a type of upside-down tree that makes decisions based on the data conditions. The question now is, why use a decision tree? Why not use different algorithms? The reason is simple: when the data is primarily categorical and dependent on circumstances, the decision tree produces outstanding results. Is it still perplexing you? Let's have a look at an example to make things clearer. Let's start with a dataset and presume we're going to use a decision tree to develop our final model. As a result, the algorithm will create a decision tree internally. RandomForest: The supervised literacy system is used by Random Forest, a well- known machine literacy algorithm. It can be used for both bracket and retrogression problems in machine literacy. It's grounded on ensemble literacy, which is a fashion for combining multiple classifiers to attack a complex problem and ameliorate the model's performance. According to the name, "Random Forest is a classifier that contains a number of decision trees on colorful subsets of a given dataset and takes the average to boost the dataset's projected delicacy."The arbitrary timber collects vaticinations from each tree and predicts the final affair grounded on the maturity votes of protrusions, rather than depending on a single decision tree. NaiveBayes: Naive Bayes is a classification technique based on Bayes' theorem that naively assumes feature independence and assigns all characteristics in a dataset the same weight (degree of importance). As a result, the approach is based on the assumption that no one feature in a dataset is linked to or influences another. KNearestNeighbour: The K-Nearest Neighbour algorithm is predicated on the Supervised Learning technique and is one among the foremost basic Machine Learning algorithms. The K-NN method assumes that the new case/data and existing cases are similar and places the new case within the category that's most almost like the prevailing categories. The K-NN method stores all available data and classifies a replacement datum supported its similarity to the prevailing data. This means that new data are often quickly sorted into a well-defined category using the K-NN method. The K-NN approach can be used for both regression and classification, but it is more commonly utilized for classification tasks. Training Data D Training MI Algorithm New Input Data Prediction False Result Correct Output Result
  • 4. International Research Journal of Engineering and Technology (IRJET) e-ISSN: 2395-0056 Volume: 09 Issue: 03 | Mar 2022 www.irjet.net p-ISSN: 2395-0072 © 2022, IRJET | Impact Factor value: 7.529 | ISO 9001:2008 Certified Journal | Page 1291 3. CONCLUSIONS: This paper offers a novel personalized real-time decision- making support system based on a hybrid prediction- and-classification machine learning system. Because it runs directly at the bedside, the suggested system is considered a breakthrough when compared to state-of- the-art real-time systems using three phase-based models. It eliminates the need for substantial offline modeling, unpredictability, and delays that come with traditional systems. The suggested novel machine learning architecture consists of two stages: a hierarchical temporal memory (HTM) predictor stage, which was first applied to medical signals, and an LSTM classifier. REFERENCES  Leonelli S. Data-centric biology: a philosophical study. Chicago: University of Chicago Press; 2016.  Marx V. Biology: The big challenges of Big Data. Nature. 2013; 498(7453):255–60.  Fieschi M, Dufour JC, Staccini P, Gouvernet J, Bouhaddou O. Medical Decision Support Systems: old dilemmas and new paradigms. Method Inform Med. 2003;42(3):190–8.  Bates DW, Kuperman GJ, Wang S, Gandhi T, Kittler A, Volk L, Spurr C, Khorasani R, Tanasijevic M, Middleton B. Ten commandments for efective clinical decision support: making the practice of evidence-based medicine a reality.JAmMedInform Assoc. 2003;10(6):523–30.  Sittig DF, Wright A, Osherof JA, Middleton B, Teich JM, Ash JS, Campbell E, Bates DW. Grand challenges in clinical decision support. J Biomed Inform. 2008;41(2):387–92. BIOGRAPHIES  Ms. D. Gayathri is an Assistant Professor in Computer Science and Engineering Sri Chandrasekharendra Saraswathi Viswa Mahavidyalaya deemed to be university, Enathur, Kanchipuram, India.  Mr. Bollineni Sandeep Sai, Student, B.E. Computer Science and Engineering, Sri Chandrasekharendra Saraswathi Viswa Mahavidyalaya deemed to be university, Enathur, Kanchipuram, India.  Mr. Chilaka Venkata Mohith, Student,B.E.Computer Science and Engineering, Sri Chandrasekharendra SarswathiViswa Mahavidyalaya deemed to be university, Enathur, Kanchipuram, India.