The DISTINCT clause allows you to remove duplicate rows from the results of a SELECT statement. It can be used with one or more columns, and returns only unique combinations of values from those columns. The LIKE condition allows pattern matching in a WHERE clause using wildcard characters like % and _. It can be used to find strings that start with, end with, or contain a specific pattern. The IN function provides an alternative way to write multiple OR conditions in a WHERE clause by listing possible values for a column.