The 308 excimer system is a handheld UVB therapy device that targets skin conditions like psoriasis and vitiligo using a narrow-band wavelength of 308 nm, allowing for effective treatment while protecting surrounding healthy skin. This system offers painless treatment, maximum targeted delivery, and can treat areas up to 16 cm². Additionally, it has low operational costs and has shown positive clinical results in numerous testimonials from medical professionals.

1. The revolutionary 308 Excimer System is the only handheld, highly effective Excimer System for monochromatic UVB therapy 308 Excimer System

2. 308 – Wavelength Optimal wavelength for UV-therapy is 300-310 nm UVC: higher risk of skin cancer UVA: more skin aging effects, effective on Psoriasis and Dermatitis, not so effective on Vitiligo NB UVB: effective and safe 200 300 400 500 600 700 800 A B C 280 320 Safety UV VISIBLE IR Efficiency 300-310nm = best ratio Efficiency / Safety

3. 308 – UVB Phototherapy – Spectral Targeting Excimer lasers and excimer systems emit narrow-band UVB Only Excimer systems are optimal for spectral targeting ! 308 Excimer systems Filtered narrow-band light Broad-band systems

4. 308 – UVB Phototherapy – Lesion Targeting The Excimer system offers lesion targeting UV booths for the entire body, expose healthy skin to UV light. This can result in over-exposure to certain areas. With the 308 Excimer System treatment is focused on lesions only, no healthy skin is exposed to UV radiation.

5. 308 Excimer System Impressive Effects UVB radiation on the skin has a stimulating effect on the skin’s immune system. This makes it possible to successfully treat skin diseases that are caused by disruptions of the immune system. UVB light has been described in medical literature as the most effective approach for the treatment of Vitiligo with the fewest side effects ᶦ ᶦ Forschner T, Bucholtz S, Stockfleth E. Current state of Vitiligo therapy-evidence based analysis of the literature. J Dtsch Dermatol Ges. 5 th June 2007, pp467-75 Applications: Psoriasis De-pigmentation Vitiligo Post CO 2 Alopecia areata

6. Psoriasis - The facts Second most common skin disorder in Western World Recurring non-contagious skin condition Raised, thickened patches of red skin Covered with silvery white scales May itch, can cause disfigurement Disruption in process of skin regeneration Built up of keratinocytes Increased cell division

7. Photographs: Courtesy from Prof. Amon, Germany 308 – Psoriasis Treatment Example Before treatment After 9 treatments

8. Vitiligo – The facts Vitiligo is depigmentation of patches of the skin Vitiligo caused by death or loss of function to the melanocyte cells Non-contagious skin condition 2 types of vitiligo: Non-Segmental (symmetry to patches of depigmentation) Segmental (aggressive and associated with dorsal roots of the spine) 1-2% affected worldwide (approx 50-60 million) 50% of cases diagnosed before the age of 20 Current treatments include: Sun cream, make-up, minigrafting, UVA and UVB light treatments

9. 308 – Vitiligo Treatment Example Before treatment After 24 treatments Photographs: Courtesy from Dr. Passeron, France

10. The system Colour touch screen Optical head (4 filters + 1 window) Connection to power supply On/Off Trigger

11. Treatment with the 308 Excimer System is painless and offers maximum protection of healthy skin through selective radiation. The 308 Excimer system can treat an area up to 16cm². Plate masks allow you to adapt the size and shape of the area you wish to treat, targeting specific lesions without exposing surrounding skin. This allows a higher light dose and reduces the number of treatment sessions.

12. Small, mobile and cost-effective Low acquisition and operating costs, maintenance No consumables, no gas needed The only handheld Excimer system worldwide Highly portable with protective carry case

13. Technical specifications Wavelength 308 nm Beam diameter 40 x 40 mm Medium output density 50 mW/cm² Power density 50 - 6000 mJ/cm² Power requirements 100 - 240 V, 0.8 A, 50/60 Hz Dimensions (L x W x H) 26 x 24 x 27 cm

14. 308 Excimer System - Testimonials “ Since 2001 we performed more than 10.000 treatments with our Excimer Laser (...) we can tell that the response time of the clinical effects in relation to the number of treatments of the Quantel Derma 308 system is absolutely equal to the Excimer Laser.” Prof. Dr. Ulrich Amon, Psorisol Klinik, Germany “ In the last years I used the Excimer laser for vitiligo and psoriasis with good clinical results. Now I use the new handheld 308 Excimer system because it is much more convenient and gives me the same clinical results.“ Moshe Lapidoth M.D., M.P.H, Dermatologist, Head of the Laser Unit, Rabin Medical Center, Israel “ After treating several patients with the 308 Excimer system, I can see that it is really powerful. The results are in some cases even better compared to my Excimer laser.“ Dr. (Univ. Istanbul) Raul Yaguboglu, DermAllegra, Germany Testimonials courtesy of Quantel Derma

15. More treatments Besides Psoriasis and vitiligo, other indications respond well to the narrowband UVB light therapy, including: Hypopigmentations Alopecia areata Mycosis fungoides Diverse atopic eczema, atopic dermatitis Erythema anulare (EAC)

16. Watch the 308 Excimer demo now http://www.youtube.com/SchucoUK Or call 020 8368 1642 for further information