The male reproductive system consists of several key structures including the testes, epididymis, seminal vesicles, prostate gland, and penis. The testes produce sperm and hormones in the seminiferous tubules. Sperm mature as they move from the testes to the epididymis. The accessory sex glands, including the seminal vesicles and prostate gland, secrete fluids that nourish and transport sperm. Contraction of muscles allows for erection and ejaculation of sperm from the penis.
1. Spermatogenesis (Spermatocytogenesis, Spermiogenesis, Spermiation, Shape and function of cells inside the Testis, Semen and sperm structure, Sperm journey after synthesis to outside)
This PPT covers Anatomy and Physiology of Male Reproductive System. It includes anatomy of male reproductive organs, spermatogenesis and hormonal regulation of testis
Male reproductive system
By Prof. Dr. R. R. Deshpande
• This PPT has following Imp Contents – Introduction ,Penis ,Scrotum , Testis , Spermatogenesis , Spermatozoon, Epididymis , Vas deferance ,Accessory Glands , Seminal Vesicle , Prostate Gland , Bulbourethral Glans , Spermatozoa , Spermatogenesis , Seminiferous tubules , Control of Spermatogenesis , Fate of Spermatozoa, Metabolism of Spermatozoa , Fertilization of Ovum, Semen
• Visit – www.ayurvedicfriend.com
Phone – 922 68 10 630
1. Spermatogenesis (Spermatocytogenesis, Spermiogenesis, Spermiation, Shape and function of cells inside the Testis, Semen and sperm structure, Sperm journey after synthesis to outside)
This PPT covers Anatomy and Physiology of Male Reproductive System. It includes anatomy of male reproductive organs, spermatogenesis and hormonal regulation of testis
Male reproductive system
By Prof. Dr. R. R. Deshpande
• This PPT has following Imp Contents – Introduction ,Penis ,Scrotum , Testis , Spermatogenesis , Spermatozoon, Epididymis , Vas deferance ,Accessory Glands , Seminal Vesicle , Prostate Gland , Bulbourethral Glans , Spermatozoa , Spermatogenesis , Seminiferous tubules , Control of Spermatogenesis , Fate of Spermatozoa, Metabolism of Spermatozoa , Fertilization of Ovum, Semen
• Visit – www.ayurvedicfriend.com
Phone – 922 68 10 630
Reproductive system
Anatomy of male and female reproductive system, Functions of male and female
reproductive system, sex hormones, physiology of menstruation, fertilization,
spermatogenesis, oogenesis, pregnancy and parturition
Involved in the development, maturation, transport and deposition of the male gametes (spermatozoa).
It consists of the paired testes,
the convoluted duct of the epididymis (ductus epididymidis),
the deferent duct (ductus deferens), the urethra (pars pelvina urethra) and the accessory glands
Reproductive and hormonal functions of the male Maryam Fida
Reproductive and hormonal functions of the male 1. Primary Sex Organs
Testes are the primary sex organs or gonads in males.
Accessory Sex Organs
Accessory sex organs in males are:
1. Seminal vesicles 2. Prostate gland
3.Urethra 4. Penis
Testis contain Seminiferous Tubules. Sperms are formed in seminiferous tubules. Testis has two important types of cells. 1.Sertoli cells are the supporting cells in seminiferous tubules. Sertoli cells provide support, protection and nourishment for the spermatogenic cells present in seminiferous tubules. Sertoli cells contain hormone “INHIBIN”. 2. Leydig cells. When stimulated by LH, they secrete:
Testosterone
Androstenedione
Dehydroepiandrosterone (DHEA)
Human reproduction is any form of sexual reproduction resulting in human fertilization. It typically involves sexual intercourse between a man and a woman. During sexual intercourse, the interaction between the male and female reproductive systems results in fertilization of the woman's ovum by the man's sperm.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
2. 7
Segments in Male Reproductive
Tract
• Spermatic Cord
• Scrotum
• Testis
• Excurrent duct system
• Accessory sex glands
• Penis and muscles for protrusion, erection and
ejaculation
4. Functions of the Spermatic Cord
• Provide Vasculature, lymphatic and
neural connection to the body
• Provide a heat exchanger
• House the cremaster muscle
4
5. 5
Anatomy of Male Reproduction
• Male Gonads, the testis, lie outside abdomen
within scrotum derived from skin & fascia
• Each testis further lies within a vaginal process a
separate extension of peritoneum. They pass
through “inguinal canal|” with ‘deep’ and
‘superficial’ rings
• Blood vessels and nerves reach the testis in
spermatic cord which also lies within the vaginal
process.
6. Functions of the testes
• To produce spermatozoa
• To produce hormones and proteins
• To produce fluids
6
• Testicular capsule
• Parenchyma
• Mediastinum
• Rete tubules
The testis consists of
7. Testicular parenchyma consists of
• Seminiferous tubules
• Interstitial cells of Leydig
• Capillaries
• Lymphatics
• Connective tissue
7
• Seminiferous epithelium
• Sertoli cells
• Developing germ cells
• Peritubular cells
The tubular compartments consists of
8. 8
Thermoregulation of Testis
• Testis for effective functioning must be maintained at the
temperature lower than that of body.
• Temperature receptors are present in the scrotal skin
• In cold conditions contraction of the smooth muscles, and
elevation of the testis and wrinkling of the skin occur.
• In hot conditions muscles relaxes and lowering testis in
pendulous scrotum
• Testicular artery is a convoluted structure & arterial coils
are enmeshed by ‘pampiniform plexus’ of testicular vein
• By virtue of countercurrent mechanism arterial blood is
cooled by venous blood leaving the testis
10. 10
Development
Descent of the testis.
• Inguinal ligament of the gonad is called the gubernaculum
testis
• Failure of testis to enter scrotum cryptorchidism
(unilateral or bilateral)
Postnatal development
• Capacity for erection of the penis precedes the appearance
of sperm in ejaculate by several months
• The period of rapid development that precedes puberty is
known as pre pubertal period
• The period after puberty is called as post pubertal
• During the post pubertal period development continues and
the reproductive tract reaches full sexual maturity months
or several years later
12. 12
Basal Compartment
Adluminal
Compartment
Sertoli cells (FSH)
Large, diffused cytoplasm of
tubule forms a barrier which
isolate the difference ting
germ cells from general
circulation.
Spermatogonium
Lies in the outermost
Spermatocyte
Located inside the
layer of Sg and Sc
Spermatids, round
Located internally to
spermatocyte
Spermatozoa production: main
function
Germinal Cells & Sertoli Cells
Arrangments in Seminiferous Tubule
BLOOD TESTIS
BARRIER
15. 15
Development of Male Reproductive
Tract in Farm Animals
Bull
(Holstein)
(weeks)
Buffalo Bull
Weeks (months)
(Ahmad et al., 1987)
Ram
(weeks)
P. Spermatocyte in SNT 24 48 (12) 12
Sperm in SNT 32 72 (18) 16
Sperm in cauda epididymis 40 72 (18) 16
Sperm in ejaculate 42 96 (24) 18
Separation between penis
and penile part of prepuce
32 60 (15) >10
Age of sexual maturity 150 192 (36) >24
17. 17
Epididymis
• Caput, (head) corpus (body) and cauda (tail)
• Progressive decrease in height of the epithelium
and stereocilia and widening of lumen
• Maturation of sperms occur during transmit
through epididymis
• Sperm stored in epididymis retain fertilizing
capacity for several weeks, cauda stores ~75% of
the total epididymal sperm
• Do the sperm in the testis have the ability to
fertilize?
• What is the fate of unejaculated Spermatozoa?
19. Seminal Plasma is produced by the
• Epididymis
• Ampulla
• Vesicular gland
• Prostate gland
• Bulbouretheral glands (Cowper’s
gland)
19
20. 20
Accessory Glands
• Seminal vesicles, in ruminants are compact
lobulated glands, lies laterally to the terminal part
of ductus deferens. They provide liquid vehicle for
the transport sperm, Contribution in the addition
of specific chemical agents to the ejaculate eg.,
fructose and citric acid.
• Prostrate glands are lobulated, external part of
the body lies out side the thick uretheral muscle.
• Bulbouretheral gland is dorsal to the urethera in
bull hidden by bulbo spongiosus muscle.
21. 21
Erection and Protrusion
• Sexual stimulation, produces dilatation of arteries,
supplying cavernous bodies of penis.
• Stiffening and straightening of the penis is caused
by ischiocavernosus muscle.
• Intromission in the bull lasts for about few
seconds.
• Straightening of the penis after withdrawal occurs
abruptly.
• Erectile dysfunction (ED) = impotence, whereas
male infertility = temporary impairment of the
semen picture