This document provides an overview of the anatomy and physiology of the heart. It begins with the functions of the heart and describes the size, shape, and location of the heart. It then discusses the layers of the heart including the pericardium, epicardium, myocardium, and endocardium. The document outlines the internal and external anatomy of the heart including the atria, ventricles, valves, vessels, and sulci. It also covers the coronary circulation, histology of cardiac muscle and conducting system, electrical properties, cardiac cycle, and heart sounds. The document contains many diagrams labeling the structures of the heart.
This document provides an overview of the cardiovascular system including blood vessels and circulation. It discusses the functions of the circulatory system and the structural features of different types of blood vessels such as arteries, veins, and capillaries. Specific topics covered include the pulmonary and systemic circulation, the major arteries and veins throughout the body, and the microstructure of different blood vessel types. The document uses diagrams and images to illustrate key anatomical structures and pathways of blood flow.
This document provides information about a course on medical histology from the University of Michigan Medical School. It discusses the copyright and terms of use for the course materials. The materials are made available under a Creative Commons license that allows for sharing and adapting with attribution. The document provides guidance on citing the materials and notes that some content may be graphic. It cautions that the materials are not meant as a replacement for medical advice.
This document summarizes the main tissue types found in animals: epithelial, connective, supportive, vascular, muscular and nervous tissue. It describes the functions and examples of each tissue type. For epithelial tissue, it distinguishes between simple and stratified epithelia. For connective tissue, it outlines the fibers, inorganic substances and organic substances that make up the matrix. It also lists the main types of connective, supportive and vascular tissues.
The document summarizes the structure and function of the respiratory system. It describes the conducting portion which includes the nasal cavity, pharynx, larynx, trachea, bronchi and bronchioles that warm and moisten air. It then describes the respiratory portion which includes respiratory bronchioles, alveolar ducts and alveoli where gas exchange occurs. It discusses the layers of the wall and types of epithelium found in the conducting portion, including ciliated columnar cells, mucous goblet cells, brush cells and basal cells.
This document contains light microscope images of decalcified compact bone and spongy bone from the Histology Department of Cairo University's Faculty of Medicine. The images show Haversian systems, Haversian canals, osteocytes, interstitial lamellae, and trabecular bone.
The respiratory system consists of conducting and respiratory portions. The conducting portion includes the nasal cavities, pharynx, larynx, trachea, and bronchi. It contains cartilage and pseudostratified ciliated columnar epithelium. The respiratory portion includes bronchioles, alveolar ducts, alveolar sacs, and alveoli. It lacks cartilage and contains simple cuboidal epithelium with Type I and II pneumocytes for gas exchange. The alveoli are surrounded by a highly vascularized connective tissue layer and are the primary sites of oxygen/carbon dioxide exchange.
The skeletal system consists of 206 bones and other tissues that provide structure, protect organs, allow movement, and produce blood cells. It includes two divisions - the axial skeleton which includes the skull, vertebral column, and thoracic cage, and the appendicular skeleton which includes the shoulder and pelvic girdles and upper and lower limbs. Bones are classified based on their shape as long, short, flat, or irregular. Joints connect bones and are classified as fibrous, cartilaginous, or synovial joints which allow different types of movement. Skeletal muscles contract through the sliding filament mechanism in response to neuronal signals at the neuromuscular junction.
Hand anatomy 2017 new microsoft power point presentationessameahady
The document summarizes the anatomy of the hand and wrist. It describes the bones that make up the skeleton of the hand including the carpus, metacarpals, and phalanges. It then discusses the muscles, ligaments, tendons, blood vessels and nerves of the hand and wrist. In particular, it outlines the structures that pass through the carpal tunnel and extensor retinaculum.
This document provides an overview of the cardiovascular system including blood vessels and circulation. It discusses the functions of the circulatory system and the structural features of different types of blood vessels such as arteries, veins, and capillaries. Specific topics covered include the pulmonary and systemic circulation, the major arteries and veins throughout the body, and the microstructure of different blood vessel types. The document uses diagrams and images to illustrate key anatomical structures and pathways of blood flow.
This document provides information about a course on medical histology from the University of Michigan Medical School. It discusses the copyright and terms of use for the course materials. The materials are made available under a Creative Commons license that allows for sharing and adapting with attribution. The document provides guidance on citing the materials and notes that some content may be graphic. It cautions that the materials are not meant as a replacement for medical advice.
This document summarizes the main tissue types found in animals: epithelial, connective, supportive, vascular, muscular and nervous tissue. It describes the functions and examples of each tissue type. For epithelial tissue, it distinguishes between simple and stratified epithelia. For connective tissue, it outlines the fibers, inorganic substances and organic substances that make up the matrix. It also lists the main types of connective, supportive and vascular tissues.
The document summarizes the structure and function of the respiratory system. It describes the conducting portion which includes the nasal cavity, pharynx, larynx, trachea, bronchi and bronchioles that warm and moisten air. It then describes the respiratory portion which includes respiratory bronchioles, alveolar ducts and alveoli where gas exchange occurs. It discusses the layers of the wall and types of epithelium found in the conducting portion, including ciliated columnar cells, mucous goblet cells, brush cells and basal cells.
This document contains light microscope images of decalcified compact bone and spongy bone from the Histology Department of Cairo University's Faculty of Medicine. The images show Haversian systems, Haversian canals, osteocytes, interstitial lamellae, and trabecular bone.
The respiratory system consists of conducting and respiratory portions. The conducting portion includes the nasal cavities, pharynx, larynx, trachea, and bronchi. It contains cartilage and pseudostratified ciliated columnar epithelium. The respiratory portion includes bronchioles, alveolar ducts, alveolar sacs, and alveoli. It lacks cartilage and contains simple cuboidal epithelium with Type I and II pneumocytes for gas exchange. The alveoli are surrounded by a highly vascularized connective tissue layer and are the primary sites of oxygen/carbon dioxide exchange.
The skeletal system consists of 206 bones and other tissues that provide structure, protect organs, allow movement, and produce blood cells. It includes two divisions - the axial skeleton which includes the skull, vertebral column, and thoracic cage, and the appendicular skeleton which includes the shoulder and pelvic girdles and upper and lower limbs. Bones are classified based on their shape as long, short, flat, or irregular. Joints connect bones and are classified as fibrous, cartilaginous, or synovial joints which allow different types of movement. Skeletal muscles contract through the sliding filament mechanism in response to neuronal signals at the neuromuscular junction.
Hand anatomy 2017 new microsoft power point presentationessameahady
The document summarizes the anatomy of the hand and wrist. It describes the bones that make up the skeleton of the hand including the carpus, metacarpals, and phalanges. It then discusses the muscles, ligaments, tendons, blood vessels and nerves of the hand and wrist. In particular, it outlines the structures that pass through the carpal tunnel and extensor retinaculum.
The document describes the anatomy and organization of the spinal cord and spinal nerves. It discusses the following key points:
- The spinal cord is approximately 45 cm long and extends from the brainstem down to the L1-L2 vertebrae. It is divided into cervical, thoracic, lumbar, sacral and coccygeal regions.
- The spinal cord has 31 pairs of spinal nerves that emerge from it and innervate different regions of the body. These include 8 cervical, 12 thoracic, 5 lumbar, 5 sacral and 1 coccygeal nerve.
- The spinal cord contains gray matter surrounding a central canal and containing neuron cell bodies, and white matter containing axons organized into
Connective tissue is the most abundant tissue type in the body and has a wide variety of functions, including connecting structures, holding organs in place, and storing lipids. Connective tissue is composed of cells within an intercellular matrix made of protein fibers and ground substance. The composition of the matrix gives each connective tissue its characteristics, with ground substance ranging from liquid to gel-like to solid depending on the tissue. The main protein fibers are collagen, which provides structure and tensile strength, and elastic fibers, which are highly elastic but less strong.
Functional Anatomy & physiology of the Basal nucleiRafid Rashid
Provides a good description of the functional anatomy & physiology of the basal nuclei/ basal ganglia for undergraduate medical students. It also describes disorders of the basal ganglia like parkinsonism & chorea.
The document provides information on the structure and functions of the liver and pancreas. It discusses the liver's location, lobes, ligaments, vascular and biliary supply. The liver receives blood from the hepatic portal vein and hepatic arteries. It secretes bile into canaliculi between hepatocytes. The bile ducts drain into the right and left hepatic ducts. The pancreas is also mentioned. The peritoneum and its derivatives are briefly introduced.
This document provides an overview of the physiology of the cardiovascular system. It begins with an introduction and outlines the components and general functions of the CVS. It then discusses the anatomy of the heart, including its chambers and valves. It describes the pathway of blood flow through the heart and lungs. It explains cardiac muscle and the cardiac conduction system, including the sinoatrial node, atrioventricular node, bundle of His, and Purkinje fibers. It concludes with a discussion of the action potential in pacemaker cells and contractile cells in the heart.
The document provides an overview of the anatomy and physiology of the heart, including:
1) A description of the internal and external structures of the heart, including the chambers, valves, conduction system, and blood flow pathway.
2) An explanation of how the heart's valves function to direct blood flow and relate to heart sounds.
3) A discussion of the heart's conductive pathway and how it is assessed clinically using electrocardiography.
The document summarizes key aspects of heart anatomy and physiology. It describes the location of the heart in the thoracic cavity and its layers, including the epicardium, myocardium, and endocardium. It explains the heart's four chambers, valves that prevent backflow of blood, and the cardiac cycle of alternating atrial and ventricular contraction and relaxation. It also outlines the cardiac conduction system that coordinates heart contractions and generates the electrocardiogram.
The document provides an overview of the cardiovascular system, including its major components and functions. It defines blood and its functions, and describes the composition of blood and the heart. The heart has four chambers - two atria and two ventricles. It explains the cardiac cycle and conduction system, including the sinoatrial node, atrioventricular node, and Purkinje fibers. The document also describes the coronary and pulmonary circulations, and the structure and function of arteries, veins, and capillaries throughout the body.
The document provides an overview of the cardiovascular system, including:
- The heart's structure, chambers, valves, and conduction system.
- Blood flow through the heart in a cardiac cycle, including systole and diastole of the atria and ventricles.
- Major blood vessels like arteries, veins, and capillaries. Pulmonary and systemic circulation are described.
- Coronary circulation which supplies blood to the heart muscle is explained in detail. Common cardiovascular diseases like coronary artery disease and myocardial infarction are also summarized.
The document summarizes cardiovascular anatomy and physiology. It describes the heart as a four-chambered pump with two circuits - pulmonary and systemic. Blood moves through arteries, arterioles, capillary beds, venules and veins. The heart walls have three layers - epicardium, myocardium, and endocardium. The heart has four chambers - right and left atria receive blood while right and left ventricles pump blood out. The document also discusses the coronary arteries that supply blood to the heart muscle.
The document summarizes cardiovascular anatomy and physiology. It describes the heart as a four-chambered pump with two circuits - pulmonary and systemic. Blood moves through arteries, arterioles, capillary beds, venules and veins. The heart walls have three layers - epicardium, myocardium, and endocardium. The heart has four chambers - right and left atria receive blood while right and left ventricles pump blood out. The document also discusses the coronary arteries that supply blood to the heart muscle.
The heart is a hollow, muscular pump located in the chest cavity. It has four chambers - two upper chambers called atria and two lower chambers called ventricles. The heart's electrical conduction system controls the heartbeat and ensures blood flows in one direction through the heart's four valves. Blood enters the right atrium from the body and is pumped to the right ventricle then to the lungs, and enters the left atrium from the lungs and is pumped by the left ventricle out to the body. The heart receives its own blood supply from the left and right coronary arteries.
The cardiovascular system consists of the heart and blood vessels. The heart is a muscular pump located in the chest cavity that pumps blood through two circuits - the pulmonary circulation and the systemic circulation. It has four chambers - two upper atria and two lower ventricles. The right side pumps deoxygenated blood to the lungs and the left side pumps oxygenated blood to the body. Important structures include the valves that ensure one-way blood flow and the specialized conduction system that coordinates heart contractions. The heart is supplied with oxygenated blood from the coronary arteries on its surface.
The document provides an overview of cardiac anatomy and physiology. It describes the layers of the heart including the epicardium, myocardium, and endocardium. It outlines the four chambers of the heart and the three types of circulation - pulmonary, systemic, and coronary. Key components of the cardiac cycle are explained such as systole, diastole, and the roles of the heart valves. The conduction system and how electrical signals trigger mechanical contraction are summarized. Factors that determine cardiac output like heart rate, preload, contractility, and afterload are also defined.
This document provides an overview of the structure and function of the heart. It describes the heart's location in the mediastinum of the thoracic cavity. It details the four chambers of the heart, as well as the layers of the heart wall. Key structures like the valves, sulci, and coronary vessels are defined. The orientation and projection points of the heart on the chest are outlined. The function of the atrioventricular and semilunar valves in regulating blood flow is summarized.
The document provides information on the cardiovascular system and heart anatomy. It discusses the heart chambers, which include the right and left atria and ventricles. It also describes the major blood vessels associated with the heart and the pathway of blood flow from the heart to the lungs and throughout the body. Additionally, it covers the layers of the heart wall, heart valves that prevent backflow of blood, and the conducting system which coordinates heart contractions.
The document describes the structure and function of the heart. It discusses the location of the heart in the mediastinum and its external and internal anatomy. The four chambers of the heart (right and left atria and ventricles) are described along with the valves that regulate blood flow. The circulations of blood through the pulmonary system and systemic circulation are also summarized. Key details about the layers of the heart wall, coronary circulation and blood flow through arteries, capillaries and veins are provided.
The document provides a detailed overview of the cardiovascular system, including the anatomy and function of the heart and circulation. It describes the layers of the heart wall, the cardiac muscle, valves, conducting system, and blood flow through the heart. It also discusses the pulmonary and systemic circuits, blood vessel anatomy, veins, capillaries, and fetal circulation. Finally, it reviews the composition of blood and the functions of red blood cells, white blood cells, and platelets.
The document describes the anatomy and organization of the spinal cord and spinal nerves. It discusses the following key points:
- The spinal cord is approximately 45 cm long and extends from the brainstem down to the L1-L2 vertebrae. It is divided into cervical, thoracic, lumbar, sacral and coccygeal regions.
- The spinal cord has 31 pairs of spinal nerves that emerge from it and innervate different regions of the body. These include 8 cervical, 12 thoracic, 5 lumbar, 5 sacral and 1 coccygeal nerve.
- The spinal cord contains gray matter surrounding a central canal and containing neuron cell bodies, and white matter containing axons organized into
Connective tissue is the most abundant tissue type in the body and has a wide variety of functions, including connecting structures, holding organs in place, and storing lipids. Connective tissue is composed of cells within an intercellular matrix made of protein fibers and ground substance. The composition of the matrix gives each connective tissue its characteristics, with ground substance ranging from liquid to gel-like to solid depending on the tissue. The main protein fibers are collagen, which provides structure and tensile strength, and elastic fibers, which are highly elastic but less strong.
Functional Anatomy & physiology of the Basal nucleiRafid Rashid
Provides a good description of the functional anatomy & physiology of the basal nuclei/ basal ganglia for undergraduate medical students. It also describes disorders of the basal ganglia like parkinsonism & chorea.
The document provides information on the structure and functions of the liver and pancreas. It discusses the liver's location, lobes, ligaments, vascular and biliary supply. The liver receives blood from the hepatic portal vein and hepatic arteries. It secretes bile into canaliculi between hepatocytes. The bile ducts drain into the right and left hepatic ducts. The pancreas is also mentioned. The peritoneum and its derivatives are briefly introduced.
This document provides an overview of the physiology of the cardiovascular system. It begins with an introduction and outlines the components and general functions of the CVS. It then discusses the anatomy of the heart, including its chambers and valves. It describes the pathway of blood flow through the heart and lungs. It explains cardiac muscle and the cardiac conduction system, including the sinoatrial node, atrioventricular node, bundle of His, and Purkinje fibers. It concludes with a discussion of the action potential in pacemaker cells and contractile cells in the heart.
The document provides an overview of the anatomy and physiology of the heart, including:
1) A description of the internal and external structures of the heart, including the chambers, valves, conduction system, and blood flow pathway.
2) An explanation of how the heart's valves function to direct blood flow and relate to heart sounds.
3) A discussion of the heart's conductive pathway and how it is assessed clinically using electrocardiography.
The document summarizes key aspects of heart anatomy and physiology. It describes the location of the heart in the thoracic cavity and its layers, including the epicardium, myocardium, and endocardium. It explains the heart's four chambers, valves that prevent backflow of blood, and the cardiac cycle of alternating atrial and ventricular contraction and relaxation. It also outlines the cardiac conduction system that coordinates heart contractions and generates the electrocardiogram.
The document provides an overview of the cardiovascular system, including its major components and functions. It defines blood and its functions, and describes the composition of blood and the heart. The heart has four chambers - two atria and two ventricles. It explains the cardiac cycle and conduction system, including the sinoatrial node, atrioventricular node, and Purkinje fibers. The document also describes the coronary and pulmonary circulations, and the structure and function of arteries, veins, and capillaries throughout the body.
The document provides an overview of the cardiovascular system, including:
- The heart's structure, chambers, valves, and conduction system.
- Blood flow through the heart in a cardiac cycle, including systole and diastole of the atria and ventricles.
- Major blood vessels like arteries, veins, and capillaries. Pulmonary and systemic circulation are described.
- Coronary circulation which supplies blood to the heart muscle is explained in detail. Common cardiovascular diseases like coronary artery disease and myocardial infarction are also summarized.
The document summarizes cardiovascular anatomy and physiology. It describes the heart as a four-chambered pump with two circuits - pulmonary and systemic. Blood moves through arteries, arterioles, capillary beds, venules and veins. The heart walls have three layers - epicardium, myocardium, and endocardium. The heart has four chambers - right and left atria receive blood while right and left ventricles pump blood out. The document also discusses the coronary arteries that supply blood to the heart muscle.
The document summarizes cardiovascular anatomy and physiology. It describes the heart as a four-chambered pump with two circuits - pulmonary and systemic. Blood moves through arteries, arterioles, capillary beds, venules and veins. The heart walls have three layers - epicardium, myocardium, and endocardium. The heart has four chambers - right and left atria receive blood while right and left ventricles pump blood out. The document also discusses the coronary arteries that supply blood to the heart muscle.
The heart is a hollow, muscular pump located in the chest cavity. It has four chambers - two upper chambers called atria and two lower chambers called ventricles. The heart's electrical conduction system controls the heartbeat and ensures blood flows in one direction through the heart's four valves. Blood enters the right atrium from the body and is pumped to the right ventricle then to the lungs, and enters the left atrium from the lungs and is pumped by the left ventricle out to the body. The heart receives its own blood supply from the left and right coronary arteries.
The cardiovascular system consists of the heart and blood vessels. The heart is a muscular pump located in the chest cavity that pumps blood through two circuits - the pulmonary circulation and the systemic circulation. It has four chambers - two upper atria and two lower ventricles. The right side pumps deoxygenated blood to the lungs and the left side pumps oxygenated blood to the body. Important structures include the valves that ensure one-way blood flow and the specialized conduction system that coordinates heart contractions. The heart is supplied with oxygenated blood from the coronary arteries on its surface.
The document provides an overview of cardiac anatomy and physiology. It describes the layers of the heart including the epicardium, myocardium, and endocardium. It outlines the four chambers of the heart and the three types of circulation - pulmonary, systemic, and coronary. Key components of the cardiac cycle are explained such as systole, diastole, and the roles of the heart valves. The conduction system and how electrical signals trigger mechanical contraction are summarized. Factors that determine cardiac output like heart rate, preload, contractility, and afterload are also defined.
This document provides an overview of the structure and function of the heart. It describes the heart's location in the mediastinum of the thoracic cavity. It details the four chambers of the heart, as well as the layers of the heart wall. Key structures like the valves, sulci, and coronary vessels are defined. The orientation and projection points of the heart on the chest are outlined. The function of the atrioventricular and semilunar valves in regulating blood flow is summarized.
The document provides information on the cardiovascular system and heart anatomy. It discusses the heart chambers, which include the right and left atria and ventricles. It also describes the major blood vessels associated with the heart and the pathway of blood flow from the heart to the lungs and throughout the body. Additionally, it covers the layers of the heart wall, heart valves that prevent backflow of blood, and the conducting system which coordinates heart contractions.
The document describes the structure and function of the heart. It discusses the location of the heart in the mediastinum and its external and internal anatomy. The four chambers of the heart (right and left atria and ventricles) are described along with the valves that regulate blood flow. The circulations of blood through the pulmonary system and systemic circulation are also summarized. Key details about the layers of the heart wall, coronary circulation and blood flow through arteries, capillaries and veins are provided.
The document provides a detailed overview of the cardiovascular system, including the anatomy and function of the heart and circulation. It describes the layers of the heart wall, the cardiac muscle, valves, conducting system, and blood flow through the heart. It also discusses the pulmonary and systemic circuits, blood vessel anatomy, veins, capillaries, and fetal circulation. Finally, it reviews the composition of blood and the functions of red blood cells, white blood cells, and platelets.
Echocardiography, Class II, Introduction to Echocardiography - Anatomy of the heart, cardiac hemodynamic concepts, coronary arteries, coronary artery branches, coronary distribution, 17 segment model, coronary perfusion, the pathway of the heart, cardiovascular blood flow, the cardiac cycle, semilunar valve function, cardiac intrinsic function, electrophysiology of the heart, electrocardiogram, phases of the cardiac cycle (chart), cardiac output, stroke volume, preload & afterload of the heart, calculation of target heart rate
The document describes the anatomy and structure of the cardiovascular system, including the heart and blood vessels. It details the layers that make up the heart walls and pericardium. It explains the coronary circulation that supplies blood to the heart muscle and lists the major arteries and veins involved in systemic and pulmonary circulation. Key anatomical features like heart valves and chambers are defined along with common congenital defects. Microscopic views of heart muscle and blood vessels are provided.
The document provides information about the cardiovascular system and the heart. It discusses the structure and functions of the heart, including the chambers, valves, conduction system, and blood flow pathways. It also covers topics like the cardiac cycle, heart sounds, electrocardiography, regulation of heart rate and blood pressure, and the different types of blood vessels. The heart pumps over 1 million gallons of blood per year to circulate oxygen and nutrients to tissues throughout the body.
Cardiovascular physiology for university studentsItsOnyii
A detailed pdf document on cardiovascular physiology for university students including structure and functions of heart, Electrocardiogram, echocardiography, chest and limb leads, Diseases and disorders of the heart.
Deep Behavioral Phenotyping in Systems Neuroscience for Functional Atlasing a...Ana Luísa Pinho
Functional Magnetic Resonance Imaging (fMRI) provides means to characterize brain activations in response to behavior. However, cognitive neuroscience has been limited to group-level effects referring to the performance of specific tasks. To obtain the functional profile of elementary cognitive mechanisms, the combination of brain responses to many tasks is required. Yet, to date, both structural atlases and parcellation-based activations do not fully account for cognitive function and still present several limitations. Further, they do not adapt overall to individual characteristics. In this talk, I will give an account of deep-behavioral phenotyping strategies, namely data-driven methods in large task-fMRI datasets, to optimize functional brain-data collection and improve inference of effects-of-interest related to mental processes. Key to this approach is the employment of fast multi-functional paradigms rich on features that can be well parametrized and, consequently, facilitate the creation of psycho-physiological constructs to be modelled with imaging data. Particular emphasis will be given to music stimuli when studying high-order cognitive mechanisms, due to their ecological nature and quality to enable complex behavior compounded by discrete entities. I will also discuss how deep-behavioral phenotyping and individualized models applied to neuroimaging data can better account for the subject-specific organization of domain-general cognitive systems in the human brain. Finally, the accumulation of functional brain signatures brings the possibility to clarify relationships among tasks and create a univocal link between brain systems and mental functions through: (1) the development of ontologies proposing an organization of cognitive processes; and (2) brain-network taxonomies describing functional specialization. To this end, tools to improve commensurability in cognitive science are necessary, such as public repositories, ontology-based platforms and automated meta-analysis tools. I will thus discuss some brain-atlasing resources currently under development, and their applicability in cognitive as well as clinical neuroscience.
Travis Hills' Endeavors in Minnesota: Fostering Environmental and Economic Pr...Travis Hills MN
Travis Hills of Minnesota developed a method to convert waste into high-value dry fertilizer, significantly enriching soil quality. By providing farmers with a valuable resource derived from waste, Travis Hills helps enhance farm profitability while promoting environmental stewardship. Travis Hills' sustainable practices lead to cost savings and increased revenue for farmers by improving resource efficiency and reducing waste.
When I was asked to give a companion lecture in support of ‘The Philosophy of Science’ (https://shorturl.at/4pUXz) I decided not to walk through the detail of the many methodologies in order of use. Instead, I chose to employ a long standing, and ongoing, scientific development as an exemplar. And so, I chose the ever evolving story of Thermodynamics as a scientific investigation at its best.
Conducted over a period of >200 years, Thermodynamics R&D, and application, benefitted from the highest levels of professionalism, collaboration, and technical thoroughness. New layers of application, methodology, and practice were made possible by the progressive advance of technology. In turn, this has seen measurement and modelling accuracy continually improved at a micro and macro level.
Perhaps most importantly, Thermodynamics rapidly became a primary tool in the advance of applied science/engineering/technology, spanning micro-tech, to aerospace and cosmology. I can think of no better a story to illustrate the breadth of scientific methodologies and applications at their best.
The debris of the ‘last major merger’ is dynamically youngSérgio Sacani
The Milky Way’s (MW) inner stellar halo contains an [Fe/H]-rich component with highly eccentric orbits, often referred to as the
‘last major merger.’ Hypotheses for the origin of this component include Gaia-Sausage/Enceladus (GSE), where the progenitor
collided with the MW proto-disc 8–11 Gyr ago, and the Virgo Radial Merger (VRM), where the progenitor collided with the
MW disc within the last 3 Gyr. These two scenarios make different predictions about observable structure in local phase space,
because the morphology of debris depends on how long it has had to phase mix. The recently identified phase-space folds in Gaia
DR3 have positive caustic velocities, making them fundamentally different than the phase-mixed chevrons found in simulations
at late times. Roughly 20 per cent of the stars in the prograde local stellar halo are associated with the observed caustics. Based
on a simple phase-mixing model, the observed number of caustics are consistent with a merger that occurred 1–2 Gyr ago.
We also compare the observed phase-space distribution to FIRE-2 Latte simulations of GSE-like mergers, using a quantitative
measurement of phase mixing (2D causticality). The observed local phase-space distribution best matches the simulated data
1–2 Gyr after collision, and certainly not later than 3 Gyr. This is further evidence that the progenitor of the ‘last major merger’
did not collide with the MW proto-disc at early times, as is thought for the GSE, but instead collided with the MW disc within
the last few Gyr, consistent with the body of work surrounding the VRM.
Or: Beyond linear.
Abstract: Equivariant neural networks are neural networks that incorporate symmetries. The nonlinear activation functions in these networks result in interesting nonlinear equivariant maps between simple representations, and motivate the key player of this talk: piecewise linear representation theory.
Disclaimer: No one is perfect, so please mind that there might be mistakes and typos.
dtubbenhauer@gmail.com
Corrected slides: dtubbenhauer.com/talks.html
ANAMOLOUS SECONDARY GROWTH IN DICOT ROOTS.pptxRASHMI M G
Abnormal or anomalous secondary growth in plants. It defines secondary growth as an increase in plant girth due to vascular cambium or cork cambium. Anomalous secondary growth does not follow the normal pattern of a single vascular cambium producing xylem internally and phloem externally.
Current Ms word generated power point presentation covers major details about the micronuclei test. It's significance and assays to conduct it. It is used to detect the micronuclei formation inside the cells of nearly every multicellular organism. It's formation takes place during chromosomal sepration at metaphase.
ESR spectroscopy in liquid food and beverages.pptxPRIYANKA PATEL
With increasing population, people need to rely on packaged food stuffs. Packaging of food materials requires the preservation of food. There are various methods for the treatment of food to preserve them and irradiation treatment of food is one of them. It is the most common and the most harmless method for the food preservation as it does not alter the necessary micronutrients of food materials. Although irradiated food doesn’t cause any harm to the human health but still the quality assessment of food is required to provide consumers with necessary information about the food. ESR spectroscopy is the most sophisticated way to investigate the quality of the food and the free radicals induced during the processing of the food. ESR spin trapping technique is useful for the detection of highly unstable radicals in the food. The antioxidant capability of liquid food and beverages in mainly performed by spin trapping technique.
EWOCS-I: The catalog of X-ray sources in Westerlund 1 from the Extended Weste...Sérgio Sacani
Context. With a mass exceeding several 104 M⊙ and a rich and dense population of massive stars, supermassive young star clusters
represent the most massive star-forming environment that is dominated by the feedback from massive stars and gravitational interactions
among stars.
Aims. In this paper we present the Extended Westerlund 1 and 2 Open Clusters Survey (EWOCS) project, which aims to investigate
the influence of the starburst environment on the formation of stars and planets, and on the evolution of both low and high mass stars.
The primary targets of this project are Westerlund 1 and 2, the closest supermassive star clusters to the Sun.
Methods. The project is based primarily on recent observations conducted with the Chandra and JWST observatories. Specifically,
the Chandra survey of Westerlund 1 consists of 36 new ACIS-I observations, nearly co-pointed, for a total exposure time of 1 Msec.
Additionally, we included 8 archival Chandra/ACIS-S observations. This paper presents the resulting catalog of X-ray sources within
and around Westerlund 1. Sources were detected by combining various existing methods, and photon extraction and source validation
were carried out using the ACIS-Extract software.
Results. The EWOCS X-ray catalog comprises 5963 validated sources out of the 9420 initially provided to ACIS-Extract, reaching a
photon flux threshold of approximately 2 × 10−8 photons cm−2
s
−1
. The X-ray sources exhibit a highly concentrated spatial distribution,
with 1075 sources located within the central 1 arcmin. We have successfully detected X-ray emissions from 126 out of the 166 known
massive stars of the cluster, and we have collected over 71 000 photons from the magnetar CXO J164710.20-455217.
ESPP presentation to EU Waste Water Network, 4th June 2024 “EU policies driving nutrient removal and recycling
and the revised UWWTD (Urban Waste Water Treatment Directive)”
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...University of Maribor
Slides from talk:
Aleš Zamuda: Remote Sensing and Computational, Evolutionary, Supercomputing, and Intelligent Systems.
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Inter-Society Networking Panel GRSS/MTT-S/CIS Panel Session: Promoting Connection and Cooperation
https://www.etran.rs/2024/en/home-english/
7. 20-7
20.2 Size, Shape, Location of the Heart
• Size of a closed fist
• Shape
– Apex: Blunt rounded point
of cone
– Base: Flat part at opposite
of end of cone
• Located in thoracic cavity
in mediastinum (central
core of the thoracic cavity;
everything in the thoracic
cavity except the lungs.)
– Important clinically when
using a stethoscope,
performing an ECG, or
performing CPR
10. 20-10
20.3 Anatomy of the Heart
• Pericardium or pericardial sac
– Fibrous pericardium: tough fibrous outer layer. Prevents over
distention; acts as anchor
– Serous pericardium: thin, transparent, inner layer. Simple squamous
epithelium
• Parietal pericardium: lines the fibrous outer layer
• Visceral pericardium (epicardium): covers heart surface
• The two are continuous and have a pericardial cavity between them filled
with pericardial fluid
13. 20-13
Heart Wall
• Three layers of tissue
– Epicardium: Serous membrane;
smooth outer surface of heart
– Myocardium: Middle layer
composed of cardiac muscle cell
and responsibility for heart
contracting
– Endocardium: Smooth inner
surface of heart chambers
• Pectinate muscles: muscular
ridges in auricles and right atrial
wall
• Trabeculae carnae: muscular
ridges and columns on inside
walls of ventricles
25. 20-25
Coronary Circulation:
Arteries
• Right coronary artery exits aorta
just superior to point where aorta exits
heart; lies in coronary sulcus. Smaller
than left. Extends to posterior aspect
of heart
– Right marginal artery to lateral wall of
right ventricle
– Posterior interventricular artery lies in
posterior interventricular sulcus, supplies
posterior and inferior aspects of heart
• Left coronary artery exits aorta near right coronary. Branches
– Anterior interventricular artery (left anterior descending artery) in
anterior interventricular sulcus
– Left marginal artery supplies lateral wall of left ventricle
– Circumflex artery extends to posterior aspect
26. Rt. Coronary Artery Branches
Anterior
Rt. ant. ventricular a.
Rt. marginal a.Rt. marginal a.
Rt. atrial a.Rt. atrial a.
Rt. conus aRt. conus a..
Rt. coronary a.
27. Rt. Coronary Artery Branches
Posterior
Rt. post. ventricular a. Rt. coronary a.
28. Lt. Coronary Artery Branches
Posterior
Posterior circumflex a.Lt. marginal a.
Lt. coronary a.
29. Lt. Coronary Artery Branches
Anterior
Lt. marginal a.
Lt. interventricular a.
Lt. ant. ventricular a.
30. Lt. Coronary Artery Branches
Posterior
Lt. marginal a. Posterior circumflex a.
32. 20-32
Coronary Circulation: Veins
• Great cardiac vein
and small cardiac vein
drain right margin of
heart
• Coronary sinus: veins
empty here then into
the right atrium
• Number of small veins
drain the rest of the
heart
39. 20-39
Heart Chambers
• Atria
– Right atrium: three major openings to
receive blood returning from the body
(superior vena cava, inferior vena cava,
coronary sinus)
– Left atrium: four openings that receive
blood from pulmonary veins
– Interatrial septum: wall between the atria.
Contains a depression, the foramen ovale, a
remnant of the fetal opening between the
atria
• Ventricles
– Atrioventricular canals: openings between
atria and respective ventricles
– Right ventricle opens to pulmonary trunk
– Left ventricle opens to aorta
– Interventricular septum between the two.
47. 20-47
Structure of the Heart Valves
• Atrioventricular valves (AV valves). Each valve has
leaf-like cusps that are attached to cone-shaped
papillary muscles by tendons (chordae tendineae).
Right has three cusps (tricuspid). Left has two cusps
(bicuspid, mitral). When valve is open, canal is
atrioventricular canal.
• Semilunar valves. Right (pulmonary); left (atrial).
Each cusp is shaped like a cup. When cusps are filled,
valve is closed; when cusps are empty, valve is open.
58. 20-58
20.5 Histology
• Heart Skeleton
– Consists of plate of
fibrous connective tissue
between atria and
ventricles
– Fibrous rings around
valves to support
– Serves as electrical
insulation between atria
and ventricles
– Provides site for muscle
attachment
59. 20-59
Cardiac Muscle
• Elongated, branching cells containing 1-2 centrally located nuclei
• Contains actin and myosin myofilaments
• Intercalated disks: specialized cell-cell contacts.
– Cell membranes interdigitate
– Desmosomes hold cells together
– Gap junctions allow action potentials to move from one cell to the next.
• Electrically, cardiac muscle of the atria and of the ventricles behaves as single
unit
64. 20-64
Conducting System
• SA node: sinoatrial node. Medial to opening of superior vena
cava. The pacemaker. Specialized cardiac muscle cells.Generate
spontaneous action potentials. Action potentials pass to atrial
muscle cells and to the AV node
• AV node: atrioventricular node. Medial to the right
atrioventricular valve. Action potentials conducted more slowly
here than in any other part of system. Ensures ventricles receive
signal to contract after atria have contracted
• AV bundle: passes through hole in cardiac skeleton to reach
interventricular septum
• Right and left bundle branches: extend beneath endocardium
to apices of right and left ventricles
• Purkinje fibers: Large diameter cardiac muscle cells with few
myofibrils. Many gap junctions. Conduct action potential to
ventricular muscle cells
66. 20-66
Differences Between Skeletal and
Cardiac Muscle Physiology
• Cardiac: action potentials conducted from cell to
cell. In skeletal, action potential conducted along
length of single fiber
• Cardiac: rate of action potential propagation is
slow because of gap junctions and small
diameter of fibers. In skeletal it is faster due to
larger diameter fibers.
• Cardiac: calcium-induced calcium release
(CICR). Movement of Ca2+
through plasma
membrane and T tubules into sarcoplasm
stimulates release of Ca2+
from sarcoplasmic
reticulum
68. 20-68
Refractory Period
• Absolute: Cardiac muscle cell completely
insensitive to further stimulation
• Relative: Cell exhibits reduced sensitivity
to additional stimulation
• Long refractory period prevents tetanic
contractions
69. 20-69
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70. 20-70
Electrocardiogram
• Record of electrical event in the
myocardium that can be correlated
with mechanical events
• P wave: depolarization of atrial
myocardium and signals onset of atrial
contraction
• QRS complex: ventricular
depolarization and signals onset of
ventricular contraction. Repolarization
of atria simultaneously.
• T wave: repolarization of ventricles;
precedes ventricular relaxation
• PQ interval or PR interval: 0.16 sec; atria contract and begin to
relax, ventricles begin to contract
• QT interval: 0.36 sec; ventricles contract and begin to relax
71. 20-71
20.7 Cardiac Cycle
• Heart is two pumps that work together, right
and left half
• Repetitive contraction (systole) and
relaxation (diastole) of heart chambers
• Blood moves through circulatory system
from areas of higher to lower pressure.
– Contraction of heart produces the pressure
73. 20-73
Period of Isovolumetric Contraction
• Begins at the completion of the QRS complex.
• Ventricular muscles start to contract, increasing the
pressure inside the ventricles. This causes the AV
valves to close, which is the beginning of ventricular
systole. The semilunar valves were closed in the
previous diastole and remain closed during this event.
• 120-130 mL of blood are in the ventricles, left from
the last diastole when the atria emptied into the
ventricles. This is referred to as the end diastolic
volume.
74. 20-74
Period of Ejection
• Pressure in the ventricle has increased to the point where it is
greater than the pressure in the pulmonary trunk/aorta. This
pushes the cusps of the semilunar valves against the walls of the
vessels, opening the valve.
• Blood is ejected from the ventricles.
• The pressures in the two ventricles are different: 120 mm Hg in
the left ventricle; 25 mm Hg in the right ventricle. Remember:
blood in the left ventricle must be pumped to the whole body;
blood in the right ventricle is pumped to the lungs.
• After the first initial spurt, pressure starts to drop.
• At the end of the period of ejection, 50-60 mL remain: end-
systolic volume.
75. 20-75
Period of Isovolumetric Relaxation
• Completion of T wave results in ventricular
repolarization and relaxation.
• Ventricular pressure falls very rapidly.
• Pulmonary trunk/aorta pressure is higher than
ventricular pressure.
• Elastic recoil of the arteries causes blood to flow
back toward the relaxed ventricles: the semilunar
valves close, which is the beginning of ventricular
diastole.
• Note that the AV valves are also closed.
76. 20-76
Passive Ventricular Filling
• While the ventricles were in systole, the atria
were filling with blood.
• Atrial pressure rises above ventricular pressure
and the AV valves open.
• Blood flows into the relaxed ventricles,
accounting for most of the ventricular filling
(70%).
77. 20-77
Active Ventricular Filling
• Depolarization of the SA node generates action potentials
that spread over the atria (P wave) and the atria contract.
This completes ventricular filling.
• At rest, contraction of atria not necessary for heart
function.
• During exercise, atrial contraction necessary for function
as heart pumps 300-400%.
80. 20-80
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81. 20-81
Heart Sounds
• First heart sound or “lubb”
– Atrioventricular valves and surrounding fluid vibrations
as valves close at beginning of ventricular systole
• Second heart sound or “dupp”
– Results from closure of aortic and pulmonary semilunar
valves at beginning of ventricular diastole, lasts longer
• Third heart sound (occasional)
– Caused by turbulent blood flow into ventricles and
detected near end of first one-third of diastole
83. 20-83
Aortic Pressure Curve
• Dicrotic notch (incisura): when the aortic
semilunar valve closes, pressure within the
aorta increases slightly
• Blood pressure measurement taken in the
arm is a reflection of aortic pressures, not
ventricular
84. 20-84
20.8 Mean Arterial Pressure
• Average blood pressure in aorta
• MAP = CO x PR
– CO is amount of blood pumped by heart per
minute
• CO = SV x HR
– SV: Stroke volume (blood pumped during each heart beat)
– HR: Heart rate (number of times heart beats per minute)
• Cardiac reserve: Difference between CO at rest and
maximum CO
– PR is total resistance against which blood must be
pumped
86. 20-86
20.9 Regulation of the Heart
• Intrinsic regulation: Results from normal
functional characteristics, not on neural or
hormonal regulation
– Preload: Starling’s law of the heart
• Preload is the amount of stretch of the
ventricular walls. The greater the stretch
(preload), the greater the force of
contraction.
– Afterload: pressure the contracting ventricles
must produce to overcome the pressure in the
aorta and move blood into the aorta. Heart not
as sensitive to this as it is to changes in preload.
87. 20-87
Regulation of the Heart
• Extrinsic regulation: Involves neural and hormonal control
– Parasympathetic stimulation
• Supplied by vagus nerve, decreases heart rate, acetylcholine is
secreted and hyperpolarizes the heart
– Sympathetic stimulation
• Supplied by cardiac nerves. Innervate the SA and AV nodes,
coronary vessels and the atrial and ventricular myocardium. Increases
heart rate and force of contraction. Epinephrine and norepinephrine
released.
• Increased heart beat causes increased cardiac output. Increased force
of contraction causes a lower end-systolic volume; heart empties to a
greater extent. Limitations: heart has to have time to fill.
– Hormonal Control. Epinephrine and norepinephrine from the adrenal
medulla. Occurs in response to increased physical activity, emotional
excitement, stress
88. 20-88
20.10 Heart and Homeostasis
• Effect of blood pressure
– Baroreceptors monitor blood pressure; in walls of internal carotids and
aorta. This sensory information goes to centers in the medulla
oblongata
• Effect of pH, carbon dioxide, oxygen
– Receptors that measure pH and carbon dioxide levels found in
hypothalamus
– Chemoreceptors monitoring oxygen levels found in aorta and internal
carotids. Prolonged lowered oxygen levels causes increased heart rate,
which increases blood pressure and can thus deliver more oxygen to the
tissues.
• Effect of extracellular ion concentration
– Increase or decrease in extracellular K+
decreases heart rate
• Effect of body temperature
– Heart rate increases when body temperature increases, heart rate
decreases when body temperature decreases
92. 20-92
20.11 Effects of Aging on the Heart
• Gradual changes in heart function, minor
under resting condition, more significant
during exercise
• Hypertrophy of left ventricle
• Maximum heart rate decreases
• Increased tendency for valves to function
abnormally and arrhythmias to occur
• Increased oxygen consumption required to
pump same amount of blood