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Circulatory Derangements II

            M1 โ€“ Cardiovascular/Respiratory
                      Sequence
                  Gerald Abrams, MD

Fall 2008
Circulatory Derangements
             II
      HEMORRHAGE
HEMORRHAGE
Escape of blood from the C-V system

     -onto the floor

     -into the tissues / body cavities
Clinical Patterns of Hemorrhage
โ€ขโ€ˆ   Petechiae โ€“ 1-2 mm. hemorrhages
โ€ขโ€ˆ   Ecchymoses- blotches / bruises
โ€ขโ€ˆ   Hematoma โ€“ a mass or lump of blood
โ€ขโ€ˆ   Hemothorax โ€“ blood in the pleural cavity
โ€ขโ€ˆ   Hemarthrosis โ€“ blood in a joint
โ€ขโ€ˆ   Hemopericardium, hematosalpinx, etcโ€ฆ.
โ€ขโ€ˆ   Purpura โ€“ a condition of widespread
               cutaneous and mucosal hemorrhages
Petechiae




G.D. Abrams, University of Michigan Medical School
Ecchymoses




 Medscape
Hematoma




Department of Pathology, University of Michigan
Purpura




Department of Pathology, University of Michigan
Hemostasis
    involves three components

โ€ขโ€ˆ Blood vessels

โ€ขโ€ˆ Platelets

โ€ขโ€ˆ Coagulation system
Department of Pathology, University of Michigan   Department of Pathology, University of Michigan
G.D. Abrams, University of Michigan Medical School
JoeD, wikimedia
Ecchymosis - Fresh




G.D. Abrams, University of Michigan Medical School
Ecchymosis - Resolving




G.D. Abrams, University of Michigan Medical School
Ecchymosis - Resolving




G.D. Abrams, University of Michigan Medical School
Erythrophagocytosis




G.D. Abrams, University of Michigan Medical School
Hemosiderin




G.D. Abrams, University of Michigan Medical School
Hematoidin




G.D. Abrams, University of Michigan Medical School
Hemosiderin & Hematoidin




G.D. Abrams, University of Michigan Medical School
Hemosiderin & Hematoidin
               Iron Stain




G.D. Abrams, University of Michigan Medical School
Aspirated Blood




Department of Pathology, University of Michigan
Pontine Hemorrhage




Department of Pathology, University of Michigan
Cerebral Hemorrhage
                    Mycotic Aneurysm




Department of Pathology, University of Michigan
Cerebral Hemorrhage
                       Hypertensive




Department of Pathology, University of Michigan
Cerebral Hemorrhage
                    Thrombocytopenic




Department of Pathology, University of Michigan
Subdural Hematoma




Department of Pathology, University of Michigan
Hemopericardium




Department of Pathology, University of Michigan
Hemopericardium




Department of Pathology, University of Michigan
Systemic Effects of Hemorrhage

โ€ขโ€ˆ Exsanguination

โ€ขโ€ˆ Shock

โ€ขโ€ˆ Anemia of Chronic Blood Loss
Liver - Lacerations




Department of Pathology, University of Michigan
Cecal Carcinoma




Department of Pathology, University of Michigan
Additional Source Information
                             for more information see: http://open.umich.edu/wiki/CitationPolicy


Slide 7:The Journal of Young Investigators, 2008 (jyi.org)
Slide 8: Medscape.com
Slide 9: Department of Pathology, University of Michigan
Slide 10: Department of Pathology, University of Michigan
Slide 12: Department of Pathology, University of Michigan; Department of Pathology, University of Michigan
Slide 13: G.D. Abrams, University of Michigan Medical School
Slide 14: JoeD, wikimedia
Slide 15: G.D. Abrams, University of Michigan Medical School
Slide 16: G.D. Abrams, University of Michigan Medical School
Slide 17: G.D. Abrams, University of Michigan Medical School
Slide 18: G.D. Abrams, University of Michigan Medical School
Slide 19: G.D. Abrams, University of Michigan Medical School
Slide 20: G.D. Abrams, University of Michigan Medical School
Slide 21:G.D. Abrams, University of Michigan Medical School
Slide 22: G.D. Abrams, University of Michigan Medical School
Slide 23: Department of Pathology, University of Michigan
Slide 24:Department of Pathology, University of Michigan
Slide 25: Department of Pathology, University of Michigan
Slide 26: Department of Pathology, University of Michigan
Slide 27: Department of Pathology, University of Michigan
Slide 28: Department of Pathology, University of Michigan
Slide 29: Department of Pathology, University of Michigan
Slide 30: Department of Pathology, University of Michigan
Slide 32: Department of Pathology, University of Michigan
Slide 33: Department of Pathology, University of Michigan

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11.13.08: Circulatory Derangements II

  • 1. Author(s): Gerald Abrams, M.D., 2009 License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution โ€“ Noncommercial โ€“ Share Alike 3.0 License: http://creativecommons.org/licenses/by-nc-sa/3.0/ We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize your ability to use, share, and adapt it. The citation key on the following slide provides information about how you may share and adapt this material. Copyright holders of content included in this material should contact open.michigan@umich.edu with any questions, corrections, or clarification regarding the use of content. For more information about how to cite these materials visit http://open.umich.edu/education/about/terms-of-use. Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosis or a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Please speak to your physician if you have questions about your medical condition. Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers.
  • 2. Citation Key for more information see: http://open.umich.edu/wiki/CitationPolicy Use + Share + Adapt { Content the copyright holder, author, or law permits you to use, share and adapt. } Public Domain โ€“ Government: Works that are produced by the U.S. Government. (USC 17 ยง105) Public Domain โ€“ Expired: Works that are no longer protected due to an expired copyright term. Public Domain โ€“ Self Dedicated: Works that a copyright holder has dedicated to the public domain. Creative Commons โ€“ Zero Waiver Creative Commons โ€“ Attribution License Creative Commons โ€“ Attribution Share Alike License Creative Commons โ€“ Attribution Noncommercial License Creative Commons โ€“ Attribution Noncommercial Share Alike License GNU โ€“ Free Documentation License Make Your Own Assessment { Content Open.Michigan believes can be used, shared, and adapted because it is ineligible for copyright. } Public Domain โ€“ Ineligible: Works that are ineligible for copyright protection in the U.S. (USC 17 ยง 102(b)) *laws in your jurisdiction may differ { Content Open.Michigan has used under a Fair Use determination. } Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (USC 17 ยง 107) *laws in your jurisdiction may differ Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses and we DO NOT guarantee that your use of the content is Fair. To use this content you should do your own independent analysis to determine whether or not your use will be Fair.
  • 3. Circulatory Derangements II M1 โ€“ Cardiovascular/Respiratory Sequence Gerald Abrams, MD Fall 2008
  • 4. Circulatory Derangements II HEMORRHAGE
  • 5. HEMORRHAGE Escape of blood from the C-V system -onto the floor -into the tissues / body cavities
  • 6. Clinical Patterns of Hemorrhage โ€ขโ€ˆ Petechiae โ€“ 1-2 mm. hemorrhages โ€ขโ€ˆ Ecchymoses- blotches / bruises โ€ขโ€ˆ Hematoma โ€“ a mass or lump of blood โ€ขโ€ˆ Hemothorax โ€“ blood in the pleural cavity โ€ขโ€ˆ Hemarthrosis โ€“ blood in a joint โ€ขโ€ˆ Hemopericardium, hematosalpinx, etcโ€ฆ. โ€ขโ€ˆ Purpura โ€“ a condition of widespread cutaneous and mucosal hemorrhages
  • 7. Petechiae G.D. Abrams, University of Michigan Medical School
  • 9. Hematoma Department of Pathology, University of Michigan
  • 10. Purpura Department of Pathology, University of Michigan
  • 11. Hemostasis involves three components โ€ขโ€ˆ Blood vessels โ€ขโ€ˆ Platelets โ€ขโ€ˆ Coagulation system
  • 12. Department of Pathology, University of Michigan Department of Pathology, University of Michigan
  • 13. G.D. Abrams, University of Michigan Medical School
  • 15. Ecchymosis - Fresh G.D. Abrams, University of Michigan Medical School
  • 16. Ecchymosis - Resolving G.D. Abrams, University of Michigan Medical School
  • 17. Ecchymosis - Resolving G.D. Abrams, University of Michigan Medical School
  • 18. Erythrophagocytosis G.D. Abrams, University of Michigan Medical School
  • 19. Hemosiderin G.D. Abrams, University of Michigan Medical School
  • 20. Hematoidin G.D. Abrams, University of Michigan Medical School
  • 21. Hemosiderin & Hematoidin G.D. Abrams, University of Michigan Medical School
  • 22. Hemosiderin & Hematoidin Iron Stain G.D. Abrams, University of Michigan Medical School
  • 23. Aspirated Blood Department of Pathology, University of Michigan
  • 24. Pontine Hemorrhage Department of Pathology, University of Michigan
  • 25. Cerebral Hemorrhage Mycotic Aneurysm Department of Pathology, University of Michigan
  • 26. Cerebral Hemorrhage Hypertensive Department of Pathology, University of Michigan
  • 27. Cerebral Hemorrhage Thrombocytopenic Department of Pathology, University of Michigan
  • 28. Subdural Hematoma Department of Pathology, University of Michigan
  • 31. Systemic Effects of Hemorrhage โ€ขโ€ˆ Exsanguination โ€ขโ€ˆ Shock โ€ขโ€ˆ Anemia of Chronic Blood Loss
  • 32. Liver - Lacerations Department of Pathology, University of Michigan
  • 33. Cecal Carcinoma Department of Pathology, University of Michigan
  • 34. Additional Source Information for more information see: http://open.umich.edu/wiki/CitationPolicy Slide 7:The Journal of Young Investigators, 2008 (jyi.org) Slide 8: Medscape.com Slide 9: Department of Pathology, University of Michigan Slide 10: Department of Pathology, University of Michigan Slide 12: Department of Pathology, University of Michigan; Department of Pathology, University of Michigan Slide 13: G.D. Abrams, University of Michigan Medical School Slide 14: JoeD, wikimedia Slide 15: G.D. Abrams, University of Michigan Medical School Slide 16: G.D. Abrams, University of Michigan Medical School Slide 17: G.D. Abrams, University of Michigan Medical School Slide 18: G.D. Abrams, University of Michigan Medical School Slide 19: G.D. Abrams, University of Michigan Medical School Slide 20: G.D. Abrams, University of Michigan Medical School Slide 21:G.D. Abrams, University of Michigan Medical School Slide 22: G.D. Abrams, University of Michigan Medical School Slide 23: Department of Pathology, University of Michigan Slide 24:Department of Pathology, University of Michigan Slide 25: Department of Pathology, University of Michigan Slide 26: Department of Pathology, University of Michigan Slide 27: Department of Pathology, University of Michigan Slide 28: Department of Pathology, University of Michigan Slide 29: Department of Pathology, University of Michigan Slide 30: Department of Pathology, University of Michigan Slide 32: Department of Pathology, University of Michigan Slide 33: Department of Pathology, University of Michigan