Catch The Vision

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Cryptic Masons Medical Research Foundation

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Catch The Vision

  1. 1. “ Catch the Vision” Cryptic Masons Medical Research Foundation
  2. 2. General Grand Council, Cryptic Masons, International <ul><li>The Vision </li></ul><ul><li>A World Class </li></ul><ul><li>Philanthropy for World </li></ul><ul><li>Class Medical Research </li></ul>
  3. 3. <ul><li>Your General Grand Council , Cryptic Masons, International and Cryptic Masons Medical Research Foundation is Advancing the Scope of Atherosclerosis Research with the Cryptic Masons Chair in Vascular Biology Research. </li></ul>
  4. 4. Purpose of CMMRF Research is “ BECAUSE ” <ul><li>Cardiovascular disease is the Number One Killer in the United States. </li></ul><ul><li>You Know Someone Who’s had a Heart Attack or Stroke. </li></ul><ul><li>You Are Committed to Improving Medicine for Future Generations. </li></ul><ul><li>YOU CARE. </li></ul>
  5. 5. Cryptic Masons Medical Research Foundation <ul><li>Since January 1, 1986 all contributions have been cumulative. </li></ul><ul><li>Located at Indiana University, Indianapolis, Indiana. </li></ul><ul><li>Many recognition levels for donations. </li></ul><ul><li>Donations are tax deductible. </li></ul><ul><li>Your Donations will live forever. They are “Never” spent. </li></ul>
  6. 6. Indiana Center for Vascular Biology& Medicine (ICVBM) Cryptic Masons Medical Research Center Indiana University, Indianapolis,Indiana
  7. 7. Mission Statement <ul><li>The Indiana Center for Vascular Biology and Medicine (ICVBM) is committed to the rapid development, testing and extension to clinical application and commercialization of new knowledge in vascular biology. The ICVBM operates with the purpose of promoting research while impacting delivery of novel and innovative medical treatment in order to achieve positive results within the health care community. </li></ul>
  8. 8. General Grand Council, Cryptic Masons, International Has Already Accomplished With the ICVBM the Following in Vascular Biology: <ul><li>1. Established a Center for Vascular Research. (ICVBM) </li></ul><ul><li>2. Establish Dr. March as Director of our Center. </li></ul><ul><li>3. Dr. March has more than 16 medical Patents </li></ul><ul><li>4. The “Closer”is being used on more than 500,000 </li></ul><ul><li>patients annually. </li></ul><ul><li>5. Several Patents deal with the delivery of medicine </li></ul><ul><li>to a damaged area. </li></ul><ul><li>6. Attracting a World Class Research Team to our </li></ul><ul><li>Center. </li></ul><ul><li>7. The Research Team has over 300 Peer reviewed </li></ul><ul><li>scientific publications to their credit. </li></ul>
  9. 9. Our Medical Director Keith March, M.D., Ph.D.
  10. 10. Dr. Keith March, M.D., Ph.D. <ul><li>Born June 4, 1963 </li></ul><ul><li>Five Children </li></ul><ul><li>Indiana University Ph. D. 1983 </li></ul><ul><li>with Highest Distinction </li></ul><ul><li>Indiana University School of Medicine </li></ul><ul><li>M.D./Ph.D. with highest Distinction 1985 </li></ul><ul><li>Post Doctoral: Indiana U. Medical Center </li></ul><ul><li>Medical Article Author & Editorial </li></ul>
  11. 11. General Grand Council has donated over $1,884,000.00
  12. 12. World Class Researchers <ul><li>Our Center includes clinicians, biologists, physicists, chemists, engineers, and technology transfer support. The participants within the center are also interacting with a highly complementary ensemble of industrial partners forming an overall consortium, with boundaries extending beyond the center itself. </li></ul>
  13. 13. Our Participants <ul><li>Our key collaborators have been found at Indiana University, Methodist Research Institute, Indiana State University, Purdue University and Rose-Hulman Institute of Technology. These participants provide across-the-board applied research, technology and experimental design to support the basic science projects. </li></ul>
  14. 14. Research Medical Team Dr. Dongming Hou <ul><li>M.D., Ph.D. -People’s Repub. of China; Post Doc – Univ. of Heidelberg,Germany Asst. Scientist – IU </li></ul><ul><li>Investigating the mechanism of restenosis and examining techniques to prevent it. </li></ul>
  15. 15. Research Medical Team Dr. Dan Meldrum <ul><li>M. D. Michigan State </li></ul><ul><li>Residency, Univ. of Colorado; Fellowship, Johns Hopkins University </li></ul><ul><li>Asst. Prof. of Surgery at Indiana University. </li></ul>
  16. 16. Dr Meldrun’s Research Team <ul><li>Standing from Left: Rajakumar Sankula Ashley Streitmatter </li></ul><ul><li>Seated from Left: Meijing Wang Ben Tsai </li></ul>
  17. 17. Dr. Dan Meldrum’s Research <ul><li>Investigating the mechanism of how the heart produces cell damaging cytokines (agents) during heart attacks or heart surgeries and targeting therapies to determine if blocking cytokines such as tumor necrosis factor (TNF) aids the heart. </li></ul><ul><li>Dr. Meldrum has authored over 100 peer reviewed scientific publications. </li></ul>
  18. 18. Research Medical Team Dr. Jalees Rehman
  19. 19. Dr. Rehman's Research <ul><li>The Rehman lab is currently researching the biology of endothelial progenitor cells as well as other stem and progenitor cells in the cardiovascular system. </li></ul><ul><li>The goal is to understand the physiological role of such cells in a healthy environment as well as how diseases can impact such cells. Understanding the biology of progenitor and stem cells may lead to novel cardiovascular therapies based on the modification of endogenous cells, and thus complement current cell therapies that involve cell transplantation. </li></ul>
  20. 20. Dr. Jalees Rehman <ul><li>M.D. Munich, Germany; Post Doc. At Univ. of Calif.; Residency at IU Internal Med.; Cardiology Fellow, IU </li></ul><ul><li>Investigating the role of stem cells and progenitor cells in cardiovascular disease. Also studying growth factors secreted by fat tissue to investigate the relationship between obesity and heart disease. </li></ul>
  21. 21. Dr. Mike Murphy <ul><li>Adult Stem Cells </li></ul><ul><li>a vascular surgeon from Duke University </li></ul><ul><li>Peripheral artery disease (PAD) </li></ul><ul><li>Enrolled five patients in the Phase I (safety) trial </li></ul>
  22. 22. Research Medical Team Dongni Feng, Research Technician <ul><li>Studying molecular mechanisms directing artery remodeling </li></ul><ul><li>NanKai University, People’s Republic of China </li></ul>
  23. 23. Research Medical Team Catharine Williams, Lab. Tech. <ul><li>Animal Science, Purdue University </li></ul><ul><li>Cell isolation to differentiate cultured cells </li></ul><ul><li>General Laboratory support and cell culture experiments. </li></ul>
  24. 24. Dr March consults with Emily Judy an IU student learning about vascular research .
  25. 25. What are our current projects? <ul><li>“ I am looking at ways for people to grow new blood vessels (angiogenesis) using special delivery methods for genes and even using one’s own cells to convey the genes. I like to think that researchers today are working to develop the medicine for tomorrow.” </li></ul><ul><li>Dr. March 7-12-2002 </li></ul>
  26. 26. CMMRF Director’s Projects: <ul><li>1. The “Closer” </li></ul><ul><li>2. Stimulating vessel growth around the </li></ul><ul><li>heart. </li></ul><ul><li>3. Extensive research investigating the role </li></ul><ul><li>of a variety of genes and cells and how </li></ul><ul><li>they interact in vascular biology. </li></ul><ul><li>4. Implement clinical programs to provide </li></ul><ul><li>excellent care to patients with all </li></ul><ul><li>vascular diseases. </li></ul>
  27. 27. “ The Closer” A Completed successful Cryptic Masons Director’s Medical Project
  28. 28. ICVBM Project #1 The Closer
  29. 29. The Vascular Closer <ul><li>Patent in place and completed </li></ul><ul><li>Produced by Abbott Vascular </li></ul><ul><li>500,000 sold in 2001 </li></ul><ul><li>Increased production in the future </li></ul><ul><li>Royalties returned to CMMRF Medical Center at Indiana University (IVCBM). </li></ul>
  30. 30. ICVBM Project #2 <ul><li>Recently ICVBM investigators have been experimenting with a groundbreaking technique to extract a special population of a patient’s own cells from the fat tissue using liposuction. We have found that we can select cells that are like stem cells and may soon be able to re-introduce them into the patient’s heart to enhance the growth of new blood vessels and possibly regenerate heart tissue. </li></ul>
  31. 31. ICVBM Project #3 Electronic Pulsation Device <ul><li>Non-Invasive device that uses electronic pulses to stimulate cell growth that produces a natural bypass around trouble areas in the coronary arteries. </li></ul>
  32. 32. Project #4 Adult Stem Cell Mediated Angiogenesis Study <ul><li>Dr. Murphy has enrolled five patients in the Phase I (safety) trial where patients’ own adult stem cells are extracted from the hip bone before being injected into the leg along the calf. Four additional patients are scheduled for treatment in February 2006. </li></ul><ul><li>Current articles listed on our Website </li></ul><ul><li>www.cmmrf.org </li></ul>
  33. 33. Dr Murphy’s Stem Cell Mediated Angiogenesis Study
  34. 34. Why is our research so Important? <ul><li>“ Due to the length of time involved in developing a device like the Closer, it is necessary to think way ahead and advance research solutions to hasten clinical applications. To shorten this process, research dollars are critical. The more parallel efforts in place, the quicker solutions are found.” </li></ul><ul><li>Dr. March 7-12-2002 </li></ul>
  35. 35. Maintaining open arteries after Angioplasty <ul><li>One novel approach being developed and tested in the ICVBM involves the use of devices emitting ultrasound energy inside arteries following stenting to help perform gene therapy and keep such vessels open. </li></ul>
  36. 36. Early diagnosis of Coronary Artery Disease <ul><li>Your ICVBM investigators are developing techniques that will detect early abnormalities in the blood vessels by imaging inflamed areas of blood vessels entirely non-invasively. </li></ul>
  37. 37. Our Cryptic Mason Goals <ul><li>1. Continued monetary support of the ICVBM. </li></ul><ul><li>2. $10,000,000 Foundation corpus for continued funding of future research. </li></ul><ul><li>3. Your commitment/pledge today will ensure our future success. </li></ul><ul><li>Visit our Website for more information </li></ul><ul><li>www.cmmrf.org </li></ul>
  38. 38. Cryptic Masons Medical Research Foundation <ul><li>“ What We Have Done For Ourselves Alone Dies With US; What We Have Done For Others And The World Is Immortal ” </li></ul><ul><li>Albert Pike </li></ul>
  39. 39. General Grand Council, Cryptic Masons, International <ul><li>Cryptic Freemasonry and World Class Medical Research </li></ul><ul><li>Working together for Tomorrow's </li></ul><ul><li>“ Visions” </li></ul><ul><li>Created for our future by </li></ul><ul><li>Andrew R. Jackson, PIM Indiana </li></ul><ul><li>CMMRF Graphic by Stephen McKim, CM Indiana </li></ul><ul><li>Copywrite protected </li></ul>

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