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Project: Ghana Emergency Medicine Collaborative
Document Title: Compartment Syndrome
Author(s): Chris DeFlitch (Penn State Hershey Medical Center), MD, FACEP 2012
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2
Compartment Syndrome
Chris DeFlitch, MD, FACEP
Director & Vice-Chair
Department of Emergency Medicine
Penn State Hershey Medical Center
3
Case Presentation
n 

n 

23yo deaf male with Left lower extremity
injury after motocross event
Questions?

4
History that’s Important
n 

Mechanism of Injury

n 

Associated Complaints

n 

Associated Injury

n 

PQRST

5
Physical Findings ?
n 

ABC’s
n 

Vital Signs

n 

Associated Injury

n 

Local Examination

n 

Joint Above & Below

n 

Neurovascular Status
6
What’s the Differential Dx?
n 

Life threatening

n 

Most Common

n 

Bizzare Stuff

n 

Things to Impress
your Attending
7
What YOUR Assessment & Plan ?
1. 
2. 
3. 
4. 
5. 

Anti-inflammatory medications ?
Narcotics ?
Imaging ?
Consultation ?
Ask the Attending ?

8
n 

n 

Your
Interpretation
Want
another
view ?

Source undetermined

9
n 

Diagnosis ?

n 

YEP…ITS NORMAL

Source undetermined

10
What’s the ED Disposition ?
1. 
2. 
3. 
4. 

Admission
Observation
Discharge
Consultation for Specific Procedure

3. DISCHARGE

11
Guess What…….
n 

The patient came back with…..

n 

Increasing PAIN, especially with Passive range of
motion
Paresthesia
Pallor
Pulselessness
Paralysis

n 

And had COMPARTMENT SYNDROME

n 

n 
n 
n 

12
Objectives
n 

Define Compartment Syndrome

n 

Understand the Pathophysiology

n 

Consider Anatomic Factors

n 

Identify Signs & Symptoms

n 

Define Diagnostic & Treatment Options
13
Compartment Syndrome
n 
n 

n 
n 

TRUE EMERGENCY
Increase Pressure in Closed space
(compartments)
Most Common with Leg Injury/Fracture
Can occur with thigh, forearm, arm,
hand, or foot injury
14
Mechanism Associated
n 
n 
n 
n 
n 
n 
n 

Crush Injury
Fractures (closed)
Burns
Prolonged Procedures/Pressure
Spontaneous Hemorrhage
External Pressure (cast, MAST)
Overuse Syndromes
15
Pathophysiology
n 

Increased Pressure in a CLOSED
compartment
n 
n 
n 

Increased Compartment Contents
Decreased Compartment Space/volume
Increased External Pressure

16
Cellular Physiology
n 

Compartment Pressure > Diastolic
Venous vascular congestion
n  Tissue Ischemia
n  Release of Histamine increasing membrane
permeability
n  Increasing Compartment Pressure
n 

n 

Arterial Vasospasm plays a minimal Role
17
Anatomic Considerations
n 

n 

CAN affect ANY
CLOSED COMPARTMENT
Leg
n 
n 
n 
n 

Anterior – MOST FREQUENT
Lateral
Deep Posterior
Superficial Posterior
18
Other Extremities
n 

Thigh
n 

n 

Quadriceps

Forearm
n 
n 

n 

Hand & Foot
n 

Interosseous

n 

Dorsal
Volar

Arm
n 
n 

Biceps
Deltoid

19
CLASSIC “5 P’s”
n 
n 
n 
n 
n 

n 

Pain
Paralysis
Paresthesia
Pallor
Pulselessness
Said together, but if they’re all there
…the 6th P…….PATIENT is in trouble
20
Clinical Presentation
n 

Pain
n 
n 
n 

n 

Out of Proportion to exam
Deep, burning,
Unrelenting

Frequent Revisit for MORE PAIN MEDS
n 

THEY AIN’T DRUG SEEKERS !!!!
21
Physical Exam

n 

Pain with PASSIVE stretching
Pain with Active Flexing
Paralysis (secondary to pain)

n 

Tense or “full” compartment

n 
n 

n 

Be Careful….some you can’t palpate

22
The other 3 P’s
n 

n 
n 

Paresthesia – earlier sign
PALLOR
Pulselessness
n 

LATE, OMINOUS SIGNS

23
Diagnosis
n 
n 
n 
n 
n 
n 

High Index of Suspicion
GOOD H&P
Insure neurovascularity Intact
Consider extremity XR
Early Orthopedic Consultation
Compartment Pressure Measurement
n 

>30 mmHg
24
Pressure Measurement
n 

Stryker Machine (needle with transducer)
n 

Baseline machine to atmosphere pressure
n 

n 
n 

Prep Area
18 G Needle into Compartment
n 

n 
n 

Should Read ZERO

Sometime hard with SMALL compartment

Inject small amount of Saline
Measure Plateau Pressure At Least 2 times
25
Tissue Pressure Gradient

n 

0 mmHg
NORMAL
10-30 mmHg Variable
30 mmHg
Microcirculation Impaired

n 

Within 30 mmHg of diastolic BP

n 
n 

n 

Tissue Ischemia
26
Complications
n 

Tissue Necrosis & Loss
n 
n 
n 
n 

n 
n 
n 

Nerve damage
Contractures
Amputation
Cosmetic Deficit

Rhabdomyolysis---Renal Failure
Hyperkalemia
Myoglobinuria
27
Fasciotomy
n 

Definitive Treatment
n 

n 

OPEN the Closed Compartment

Indication For Fasciotomy
Pressures >30
n  Pressures within 30mmHg of Mean Arterial
Pressure
n 

28
Back to the Patient
n 

Had Clinical findings of Compartment
syndrome
n 
n 
n 
n 

LATE Findings
Flown to Tertiary Care Medical Center
Fasciotomy
Prolonged Course

29
The OUTCOME
n 

n 

He still has his Leg
BUT with a
Significant Cosmetic
& Functional Defect

30
QUESTIONS ?
THANK YOU !!!!!

31

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GEMC- Compartment Syndrome- Resident Training

  • 1. Project: Ghana Emergency Medicine Collaborative Document Title: Compartment Syndrome Author(s): Chris DeFlitch (Penn State Hershey Medical Center), MD, FACEP 2012 License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution Share Alike-3.0 License: http://creativecommons.org/licenses/by-sa/3.0/ We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize your ability to use, share, and adapt it. These lectures have been modified in the process of making a publicly shareable version. The citation key on the following slide provides information about how you may share and adapt this material. Copyright holders of content included in this material should contact open.michigan@umich.edu with any questions, corrections, or clarification regarding the use of content. For more information about how to cite these materials visit http://open.umich.edu/privacy-and-terms-use. Any medical information in this material is intended to inform and educate and is not a tool for self-diagnosis or a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional. Please speak to your physician if you have questions about your medical condition. Viewer discretion is advised: Some medical content is graphic and may not be suitable for all viewers. 1
  • 2. Attribution Key for more information see: http://open.umich.edu/wiki/AttributionPolicy Use + Share + Adapt { Content the copyright holder, author, or law permits you to use, share and adapt. } Public Domain – Government: Works that are produced by the U.S. Government. (17 USC § 105) Public Domain – Expired: Works that are no longer protected due to an expired copyright term. Public Domain – Self Dedicated: Works that a copyright holder has dedicated to the public domain. Creative Commons – Zero Waiver Creative Commons – Attribution License Creative Commons – Attribution Share Alike License Creative Commons – Attribution Noncommercial License Creative Commons – Attribution Noncommercial Share Alike License GNU – Free Documentation License Make Your Own Assessment { Content Open.Michigan believes can be used, shared, and adapted because it is ineligible for copyright. } Public Domain – Ineligible: Works that are ineligible for copyright protection in the U.S. (17 USC § 102(b)) *laws in your jurisdiction may differ { Content Open.Michigan has used under a Fair Use determination. } Fair Use: Use of works that is determined to be Fair consistent with the U.S. Copyright Act. (17 USC § 107) *laws in your jurisdiction may differ Our determination DOES NOT mean that all uses of this 3rd-party content are Fair Uses and we DO NOT guarantee that your use of the content is Fair. To use this content you should do your own independent analysis to determine whether or not your use will be Fair. 2
  • 3. Compartment Syndrome Chris DeFlitch, MD, FACEP Director & Vice-Chair Department of Emergency Medicine Penn State Hershey Medical Center 3
  • 4. Case Presentation n  n  23yo deaf male with Left lower extremity injury after motocross event Questions? 4
  • 5. History that’s Important n  Mechanism of Injury n  Associated Complaints n  Associated Injury n  PQRST 5
  • 6. Physical Findings ? n  ABC’s n  Vital Signs n  Associated Injury n  Local Examination n  Joint Above & Below n  Neurovascular Status 6
  • 7. What’s the Differential Dx? n  Life threatening n  Most Common n  Bizzare Stuff n  Things to Impress your Attending 7
  • 8. What YOUR Assessment & Plan ? 1.  2.  3.  4.  5.  Anti-inflammatory medications ? Narcotics ? Imaging ? Consultation ? Ask the Attending ? 8
  • 11. What’s the ED Disposition ? 1.  2.  3.  4.  Admission Observation Discharge Consultation for Specific Procedure 3. DISCHARGE 11
  • 12. Guess What……. n  The patient came back with….. n  Increasing PAIN, especially with Passive range of motion Paresthesia Pallor Pulselessness Paralysis n  And had COMPARTMENT SYNDROME n  n  n  n  12
  • 13. Objectives n  Define Compartment Syndrome n  Understand the Pathophysiology n  Consider Anatomic Factors n  Identify Signs & Symptoms n  Define Diagnostic & Treatment Options 13
  • 14. Compartment Syndrome n  n  n  n  TRUE EMERGENCY Increase Pressure in Closed space (compartments) Most Common with Leg Injury/Fracture Can occur with thigh, forearm, arm, hand, or foot injury 14
  • 15. Mechanism Associated n  n  n  n  n  n  n  Crush Injury Fractures (closed) Burns Prolonged Procedures/Pressure Spontaneous Hemorrhage External Pressure (cast, MAST) Overuse Syndromes 15
  • 16. Pathophysiology n  Increased Pressure in a CLOSED compartment n  n  n  Increased Compartment Contents Decreased Compartment Space/volume Increased External Pressure 16
  • 17. Cellular Physiology n  Compartment Pressure > Diastolic Venous vascular congestion n  Tissue Ischemia n  Release of Histamine increasing membrane permeability n  Increasing Compartment Pressure n  n  Arterial Vasospasm plays a minimal Role 17
  • 18. Anatomic Considerations n  n  CAN affect ANY CLOSED COMPARTMENT Leg n  n  n  n  Anterior – MOST FREQUENT Lateral Deep Posterior Superficial Posterior 18
  • 19. Other Extremities n  Thigh n  n  Quadriceps Forearm n  n  n  Hand & Foot n  Interosseous n  Dorsal Volar Arm n  n  Biceps Deltoid 19
  • 20. CLASSIC “5 P’s” n  n  n  n  n  n  Pain Paralysis Paresthesia Pallor Pulselessness Said together, but if they’re all there …the 6th P…….PATIENT is in trouble 20
  • 21. Clinical Presentation n  Pain n  n  n  n  Out of Proportion to exam Deep, burning, Unrelenting Frequent Revisit for MORE PAIN MEDS n  THEY AIN’T DRUG SEEKERS !!!! 21
  • 22. Physical Exam n  Pain with PASSIVE stretching Pain with Active Flexing Paralysis (secondary to pain) n  Tense or “full” compartment n  n  n  Be Careful….some you can’t palpate 22
  • 23. The other 3 P’s n  n  n  Paresthesia – earlier sign PALLOR Pulselessness n  LATE, OMINOUS SIGNS 23
  • 24. Diagnosis n  n  n  n  n  n  High Index of Suspicion GOOD H&P Insure neurovascularity Intact Consider extremity XR Early Orthopedic Consultation Compartment Pressure Measurement n  >30 mmHg 24
  • 25. Pressure Measurement n  Stryker Machine (needle with transducer) n  Baseline machine to atmosphere pressure n  n  n  Prep Area 18 G Needle into Compartment n  n  n  Should Read ZERO Sometime hard with SMALL compartment Inject small amount of Saline Measure Plateau Pressure At Least 2 times 25
  • 26. Tissue Pressure Gradient n  0 mmHg NORMAL 10-30 mmHg Variable 30 mmHg Microcirculation Impaired n  Within 30 mmHg of diastolic BP n  n  n  Tissue Ischemia 26
  • 27. Complications n  Tissue Necrosis & Loss n  n  n  n  n  n  n  Nerve damage Contractures Amputation Cosmetic Deficit Rhabdomyolysis---Renal Failure Hyperkalemia Myoglobinuria 27
  • 28. Fasciotomy n  Definitive Treatment n  n  OPEN the Closed Compartment Indication For Fasciotomy Pressures >30 n  Pressures within 30mmHg of Mean Arterial Pressure n  28
  • 29. Back to the Patient n  Had Clinical findings of Compartment syndrome n  n  n  n  LATE Findings Flown to Tertiary Care Medical Center Fasciotomy Prolonged Course 29
  • 30. The OUTCOME n  n  He still has his Leg BUT with a Significant Cosmetic & Functional Defect 30