The document introduces new products from AB SCIEX for 2012, including the 6500 Series triple quadrupole and QTRAP mass spectrometers with IonDrive Technology. IonDrive Technology features an IonDrive Turbo V source to produce more ions, an IonDrive QJet ion guide to better transmit and focus ions, and an IonDrive HE detector. The new instruments offer up to 10x increased sensitivity and 20x increased dynamic range over previous models. The document also highlights SelexION technology for improved selectivity and the ekspert microLC 200 for faster micro-UHPLC separations.

1. New Products in 2012
The New TripleQuad™ 6500 & QTRAP® 6500
Systems
with IonDrive™ Technology
The new AB SCIEX 6500 Series with
multi-component IonDrive™ Technology
AB SCIEX’s most sensitive triple quad
• up to 10X increase in sensitivity
• Up to 20X increase in detector
dynamic range
- all with no compromise in mass range.
1 © 2012 AB SCIEX

2. IonDrive™ Technology Key Innovations
IonDrive™ Turbo V Source IonDrive™ QJet Guide IonDrive™ HE Detector
Driving Performance by Driving More Ions While Maintaining Ruggedness
Higher sensitivity
Extended mass range m/z 5 – 2,000 with advanced dual RF
electronics
Extended dynamic range
SelexION™ technology compatible
Faster MRM3
2 © 2012 AB SCIEX

3. IonDrive™ Turbo V Source – Produce More Ions
Original Turbo V™ New IonDrive Turbo V
3 © 2012 AB SCIEX

4. IonDrive™ QJet Ion Guide – A Dual Stage RF Ion
Guide
Computed gas flow model showing flow through the ion guide
Larger diameter of first stage  Better ion capture
Smaller diameter of second stage  Better focusing into Q0
End Result: More ions transmitted, fewer neutrals reaching Q0
4 © 2012 AB SCIEX

5. Two Software Selectable Mass Ranges
5 © 2012 AB SCIEX

6. New Products in 2012
SelexION™ Technology - A higher level of Selectivity
Salmeterol without SelexION Salmeterol with SelexION
S/N = 3
S/N = 252
6 © 2012 AB SCIEX

7. New Products in 2012
ekspert™ microLC 200
The world’s only dedicated
micro-UHPLC designed to
deliver up to fivefold faster
separations and up to
fourfold improved sensitivity
• Reduction in mobile phase
costs up to 95%
• Designed specifically for
high throughput mass
spectrometry laboratories
• Ideal for pharmaceutical
applications – small
molecules and biologics
7 © 2012 AB SCIEX