In these times of low oil and gas prices, the drive to provide 'more for less' has never been greater. One key component in achieving this is the ability to accurately monitor the production rates along a wellbore and across a reservoir. Ideally a range of different measurements should be available on-demand from all points in all wells. Clearly conventional sensors such as downhole pressure and temperature gauges, flow meters, geophone arrays and production logging tools can provide part of the solution but the cost of all these different sensors limits their widespread deployment. Fibre-optic Distributed Acoustic Sensing, or DAS for short, is changing that. Using an optical fibre deployed in a cable from surface to the toe of a well DAS, often in combination with fibre-optic Distributed Temperature Sensing (DTS), provides a means of acquiring high resolution seismic, acoustic and temperature data at all points in real-time. Since the first downhole demonstrations of DAS technology in 2009 there has been rapid progress in developing the technology and applications, to the point where today it is being used to monitor the efficiency of hydraulic fracture treatments, provides continuous flow profiling across the entire wellbore and is used as a uniquely capable tool for borehole seismic acquisition. With optical fibre installed in your wells and DAS acquiring data, there is now the ability to cost effectively and continuously monitor wells and reservoirs to manage them in real-time in order to optimise production.
Modern oil and gas field management is increasingly reliant on detailed and precise 3D reservoir characterisation, and timely areal monitoring. Borehole seismic techniques bridge the gap between remote surface-seismic observations and downhole reservoir evaluation: Borehole seismic data provide intrinsically higher-resolution, higher-fidelity images than surface-seismic data in the vicinity of the wellbore, and unique access to properties of seismic wavefields to enhance surface-seismic imaging. With the advent of new, operationally-efficient very large wireline receiver arrays; fiber-optic recording using Distributed Acoustic Sensing (DAS); the crosswell seismic reflection technique, and advanced seismic imaging algorithms such as Reverse Time Migration, a new wave of borehole seismic technologies is revolutionizing 3D seismic reservoir characterization and on-demand reservoir surveillance. New borehole seismic technologies are providing deeper insights into static reservoir architecture and properties, and into dynamic reservoir performance for conventional water-flood production, EOR, and CO2 sequestration – in deepwater, unconventional, full-field, and low-footprint environments. This lecture will begin by illustrating the wide range of borehole seismic solutions for reservoir characterization and monitoring, using a diverse set of current- and recent case study examples – through which the audience will gain an understanding of the appropriate use of borehole seismic techniques for field development and management. The lecture will then focus on DAS, explaining how the technique works; its capability to deliver conventional borehole seismic solutions (with key advantages over geophones); then describing DAS’s dramatic impact on field monitoring applications and business-critical decisions. New and enhanced borehole seismic techniques – especially with DAS time-lapse monitoring – are ready to deliver critical reservoir management solutions for your fields.
PSC-Best Practices for Using Near Infrared Instrumentation for the Frac Sand ...Bob Schumann
An overview of using near infrared (NIR) instrumentation to measure moisture in frac sand. Presented by Marty Peters at 2020 North America Frac Sand Conference
In these times of low oil and gas prices, the drive to provide 'more for less' has never been greater. One key component in achieving this is the ability to accurately monitor the production rates along a wellbore and across a reservoir. Ideally a range of different measurements should be available on-demand from all points in all wells. Clearly conventional sensors such as downhole pressure and temperature gauges, flow meters, geophone arrays and production logging tools can provide part of the solution but the cost of all these different sensors limits their widespread deployment. Fibre-optic Distributed Acoustic Sensing, or DAS for short, is changing that. Using an optical fibre deployed in a cable from surface to the toe of a well DAS, often in combination with fibre-optic Distributed Temperature Sensing (DTS), provides a means of acquiring high resolution seismic, acoustic and temperature data at all points in real-time. Since the first downhole demonstrations of DAS technology in 2009 there has been rapid progress in developing the technology and applications, to the point where today it is being used to monitor the efficiency of hydraulic fracture treatments, provides continuous flow profiling across the entire wellbore and is used as a uniquely capable tool for borehole seismic acquisition. With optical fibre installed in your wells and DAS acquiring data, there is now the ability to cost effectively and continuously monitor wells and reservoirs to manage them in real-time in order to optimise production.
Modern oil and gas field management is increasingly reliant on detailed and precise 3D reservoir characterisation, and timely areal monitoring. Borehole seismic techniques bridge the gap between remote surface-seismic observations and downhole reservoir evaluation: Borehole seismic data provide intrinsically higher-resolution, higher-fidelity images than surface-seismic data in the vicinity of the wellbore, and unique access to properties of seismic wavefields to enhance surface-seismic imaging. With the advent of new, operationally-efficient very large wireline receiver arrays; fiber-optic recording using Distributed Acoustic Sensing (DAS); the crosswell seismic reflection technique, and advanced seismic imaging algorithms such as Reverse Time Migration, a new wave of borehole seismic technologies is revolutionizing 3D seismic reservoir characterization and on-demand reservoir surveillance. New borehole seismic technologies are providing deeper insights into static reservoir architecture and properties, and into dynamic reservoir performance for conventional water-flood production, EOR, and CO2 sequestration – in deepwater, unconventional, full-field, and low-footprint environments. This lecture will begin by illustrating the wide range of borehole seismic solutions for reservoir characterization and monitoring, using a diverse set of current- and recent case study examples – through which the audience will gain an understanding of the appropriate use of borehole seismic techniques for field development and management. The lecture will then focus on DAS, explaining how the technique works; its capability to deliver conventional borehole seismic solutions (with key advantages over geophones); then describing DAS’s dramatic impact on field monitoring applications and business-critical decisions. New and enhanced borehole seismic techniques – especially with DAS time-lapse monitoring – are ready to deliver critical reservoir management solutions for your fields.
PSC-Best Practices for Using Near Infrared Instrumentation for the Frac Sand ...Bob Schumann
An overview of using near infrared (NIR) instrumentation to measure moisture in frac sand. Presented by Marty Peters at 2020 North America Frac Sand Conference
Groundwater and CO2CRC - insights from the Otway project and monitoring activ...Global CCS Institute
The Groundwater and Storage interactions project arose out of a meeting on the shoulder of the Greenhouse Gas Technologies Conference in Amsterdam in 2010. It was decided to concentrate initially on the Australian Flagships projects. On 3 May 2011 Australian researchers and government agencies met and presented their work to date.
In these slides, Allison Hortle, Senior Researcher, Petroleum Hydrogeology, Cooperative Research Centre for Greenhouse Gas Technologies (CO2CRC), presents Groundwater and CO2CRC - Insights from the Otway Project and Monitoring Activities
Drilling systems automation is the real-time reliance on digital technology in creating a wellbore. It encompasses downhole tools and systems, surface drilling equipment, remote monitoring and the use of models and simulations while drilling. While its scope is large, its potential benefits are impressive, among them: fewer workers exposed to rig-floor hazards, the ability to realize repeatable performance drilling, and lower drilling risk. While drilling systems automation includes new drilling technology, it is most importantly a collaborative infrastructure for performance drilling. In 2008, a small group of engineers and scientists attending an SPE conference noted that automation was becoming a key topic in drilling and they formed a technical section to investigate it further. By 2015, the group reached a membership of sixteen hundred as the technology rapidly gaining acceptance. Why so much interest? The benefits and promises of an automated approach to drilling address the safety and fundamental economics of drilling. What will it take? Among the answers are an open collaborative digital environment at the wellsite, an openness of mind to digital technologies, and modified or new business practices. What are the barriers? The primary barrier is a lack of understanding and a fear of automation. When will it happen? It is happening now. Digital technologies are transforming the infrastructure of the drilling industry. Drilling systems automation uses this infrastructure to deliver safety and performance, and address cost.
Ultrasonic pulse echo testing has been proven to be complementary to other NDT techniques. The leading products by Proceq help to identify defects that are not detectable e.g. with radar or eddy current tests. In particular, deep scanning of walls and linings, finding of deep and second or third layer rebars and tendon duct analysis deliver unrivalled results compared to other techniques. However, the case studies presented in this paper also highlight some of the issues that need to be looked at in order to increase the value of on site pulse echo testing. Scanning speed has been one key issue that has been partially addressed through the introduction of real time B-scan imaging incl. an immediate onboard feature to create panoramic scan images out of individual scans. It has also been recognized that 3D imaging and variable slicing of the scan data help a great deal in visualizing the structural features.
A few recent advancements have been laid out in this paper, however, the authors realize that further steps are needed to fully explore the power of this NDT technology. One further step in this is use artificial intelligence positioning systems and improved image stitching to expedite and ease on-site usage of the system. Also an onboard data interpretation system is underway and ready for release to the markets, which can be particular helpful when the initial test reports are already created on-site. Finally, an on-site 3D analysis will be introduced into the next generation of instruments as well to bring ultrasonic pulse echo testing of concrete structures to the next level.
Slides discuss Neodren®, an alternative subsurface seawater intakes technology utilizing horizontal directional drilling (HDD) to insert horizontal sub-seafloor drain, including current operating plant performance data.
Nick - Benefits of Using Combined Bathymetry and Side Scan Sonar in Shallow W...Codevintec Italiana srl
Codevintec Days 2018 - Trieste
EDGETECH - Nick - Benefits of Using Combined Bathymetry and Side Scan Sonar in Shallow Water Surveys
Codevintec Days 2018 - Trieste
Relazione di Nick Lawrence - Edgetech
Groundwater and CO2CRC - insights from the Otway project and monitoring activ...Global CCS Institute
The Groundwater and Storage interactions project arose out of a meeting on the shoulder of the Greenhouse Gas Technologies Conference in Amsterdam in 2010. It was decided to concentrate initially on the Australian Flagships projects. On 3 May 2011 Australian researchers and government agencies met and presented their work to date.
In these slides, Allison Hortle, Senior Researcher, Petroleum Hydrogeology, Cooperative Research Centre for Greenhouse Gas Technologies (CO2CRC), presents Groundwater and CO2CRC - Insights from the Otway Project and Monitoring Activities
Drilling systems automation is the real-time reliance on digital technology in creating a wellbore. It encompasses downhole tools and systems, surface drilling equipment, remote monitoring and the use of models and simulations while drilling. While its scope is large, its potential benefits are impressive, among them: fewer workers exposed to rig-floor hazards, the ability to realize repeatable performance drilling, and lower drilling risk. While drilling systems automation includes new drilling technology, it is most importantly a collaborative infrastructure for performance drilling. In 2008, a small group of engineers and scientists attending an SPE conference noted that automation was becoming a key topic in drilling and they formed a technical section to investigate it further. By 2015, the group reached a membership of sixteen hundred as the technology rapidly gaining acceptance. Why so much interest? The benefits and promises of an automated approach to drilling address the safety and fundamental economics of drilling. What will it take? Among the answers are an open collaborative digital environment at the wellsite, an openness of mind to digital technologies, and modified or new business practices. What are the barriers? The primary barrier is a lack of understanding and a fear of automation. When will it happen? It is happening now. Digital technologies are transforming the infrastructure of the drilling industry. Drilling systems automation uses this infrastructure to deliver safety and performance, and address cost.
Ultrasonic pulse echo testing has been proven to be complementary to other NDT techniques. The leading products by Proceq help to identify defects that are not detectable e.g. with radar or eddy current tests. In particular, deep scanning of walls and linings, finding of deep and second or third layer rebars and tendon duct analysis deliver unrivalled results compared to other techniques. However, the case studies presented in this paper also highlight some of the issues that need to be looked at in order to increase the value of on site pulse echo testing. Scanning speed has been one key issue that has been partially addressed through the introduction of real time B-scan imaging incl. an immediate onboard feature to create panoramic scan images out of individual scans. It has also been recognized that 3D imaging and variable slicing of the scan data help a great deal in visualizing the structural features.
A few recent advancements have been laid out in this paper, however, the authors realize that further steps are needed to fully explore the power of this NDT technology. One further step in this is use artificial intelligence positioning systems and improved image stitching to expedite and ease on-site usage of the system. Also an onboard data interpretation system is underway and ready for release to the markets, which can be particular helpful when the initial test reports are already created on-site. Finally, an on-site 3D analysis will be introduced into the next generation of instruments as well to bring ultrasonic pulse echo testing of concrete structures to the next level.
Slides discuss Neodren®, an alternative subsurface seawater intakes technology utilizing horizontal directional drilling (HDD) to insert horizontal sub-seafloor drain, including current operating plant performance data.
Nick - Benefits of Using Combined Bathymetry and Side Scan Sonar in Shallow W...Codevintec Italiana srl
Codevintec Days 2018 - Trieste
EDGETECH - Nick - Benefits of Using Combined Bathymetry and Side Scan Sonar in Shallow Water Surveys
Codevintec Days 2018 - Trieste
Relazione di Nick Lawrence - Edgetech
The webinar is all about Ultra High Pressure Liquid Chromatography (UHPLC) performance and how new column technology can deliver the best separation power and be married with the best UHPLC system to ensure an outstanding result. It covers how chromatographers can ensure that even very complex and unfamiliar samples are assayed with the highest scrutiny possible? The webinar discusses how to get the most out of solid core column technology with the right UHPLC system. It covers the use of an extremely long column approach for ultra-high resolution assays and the outlines the importance of robustness and retention time stability.
No more sampling! The Distek Opt-Diss 410 in-situ fiber optic UV system measures directly in the vessel, eliminating the need for conventional sampling, and with-it consumables like filters, tubing and syringes, saving time, labor, and money. Moving light rather than liquids also allows generating near real-time dissolution data and nearly limitless sample points as frequently as every five seconds.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
What is greenhouse gasses and how many gasses are there to affect the Earth.moosaasad1975
What are greenhouse gasses how they affect the earth and its environment what is the future of the environment and earth how the weather and the climate effects.
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.