The document presents an overview of the Ecohealth and One Health frameworks, emphasizing the interconnectedness of human, animal, and environmental health through systemic and participatory approaches. It outlines the historical development of these concepts, their key principles such as transdisciplinarity and social equity, and the importance of integrating multiple disciplines in addressing complex health issues. Additionally, it highlights challenges faced in implementing ecohealth and one health initiatives, including the need for localized research and long-term commitment to achieve sustainable outcomes.