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BULLOUS DISORDERS
INTRODUCTION
• BSD are skin conditions characterised by blister formation.
• A blister is an accumulation of fluid between cells of the
epidermis or upper dermis.
• Causes of blister could be genetic, physical, inflammatory,
immunologic and as a reaction to drugs.
• BSDs are mostly autoimmune .
CAUSES
• Exposure to ultraviolet light
• Radiation therapy
• Drugs like:- furosemide
• Non steroidal anti-inflammatory agents,
• captopril
• Penicillamine
• antibiotics.
TYPES
1. Genetic Blistering Diseases:
A. Epidermolysis Bullosa B . Hailey-Hailey disease ( Benign
familial pemphigus)
2. Immunobullous Diseases:
A. Intraepidermal Immunobullous Diseases:
1.Pemphigus Vulgaris (PV) 2. Pemphigus vegetans .
3. Pemphigus foliaceus 4. Pemphigus erythematosus
5. Paraneoplastic P
B. Subepidermal Immunobullous Diseases:
1.Bullous Pemphigoid 4. Pemphigoid Gestations
2. Linear IgA disease 5. Epidermolysis Bullosa Acquisita
3. Dermatitis Herpitiforms
IMMUNOLOGIC BULLOUS
DISORDERS
• Pemphigus
• Pemphigoid
• Dermatitis Herpetiformis (DH)
• Chronic dermatoses of childhood (linear IgA dis.)
PEMPHIGUS
• Pemphigus is a rare group of blistering autoimmune diseases
that affect the skin and mucous membranes.
BULLOUS PEMPHIGOID
• an autoimmune blistering disorder
• Antibodies binds to normal skin at the BMZ(basement
membrane zone)
• It is more common than pemphigus
• Mainly affect the elderly
• Mucosal involvement is rare
BULLOUS PEMPHIGOID
• Duhring’s disease is a chronic blistering
skin condition, characterised by blisters filled with a watery
fluid.
• It is also known as Dermatitis herpetiformis
ICD-10-CM GUIDELINES
• Pemphigus-L10
• Other acantholytic disorders-L11
• Pemphigoid-L12
• Other bullous disorders-L13
• Bullous disorders in diseases classified elsewhere-L14
• Code first underlying disease.
• https://www.medesunglobal.com
THANK YOU

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Bullous disorders

  • 2. INTRODUCTION • BSD are skin conditions characterised by blister formation. • A blister is an accumulation of fluid between cells of the epidermis or upper dermis. • Causes of blister could be genetic, physical, inflammatory, immunologic and as a reaction to drugs. • BSDs are mostly autoimmune .
  • 3. CAUSES • Exposure to ultraviolet light • Radiation therapy • Drugs like:- furosemide • Non steroidal anti-inflammatory agents, • captopril • Penicillamine • antibiotics.
  • 4. TYPES 1. Genetic Blistering Diseases: A. Epidermolysis Bullosa B . Hailey-Hailey disease ( Benign familial pemphigus) 2. Immunobullous Diseases: A. Intraepidermal Immunobullous Diseases: 1.Pemphigus Vulgaris (PV) 2. Pemphigus vegetans . 3. Pemphigus foliaceus 4. Pemphigus erythematosus 5. Paraneoplastic P B. Subepidermal Immunobullous Diseases: 1.Bullous Pemphigoid 4. Pemphigoid Gestations 2. Linear IgA disease 5. Epidermolysis Bullosa Acquisita 3. Dermatitis Herpitiforms
  • 5. IMMUNOLOGIC BULLOUS DISORDERS • Pemphigus • Pemphigoid • Dermatitis Herpetiformis (DH) • Chronic dermatoses of childhood (linear IgA dis.)
  • 6. PEMPHIGUS • Pemphigus is a rare group of blistering autoimmune diseases that affect the skin and mucous membranes.
  • 7. BULLOUS PEMPHIGOID • an autoimmune blistering disorder • Antibodies binds to normal skin at the BMZ(basement membrane zone) • It is more common than pemphigus • Mainly affect the elderly • Mucosal involvement is rare
  • 9. • Duhring’s disease is a chronic blistering skin condition, characterised by blisters filled with a watery fluid. • It is also known as Dermatitis herpetiformis
  • 10. ICD-10-CM GUIDELINES • Pemphigus-L10 • Other acantholytic disorders-L11 • Pemphigoid-L12 • Other bullous disorders-L13 • Bullous disorders in diseases classified elsewhere-L14 • Code first underlying disease. • https://www.medesunglobal.com